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The Human Upgrade: Biohacking for Longevity & Performance — Alternative Health
The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey – the Father of Biohacking and creator of Bulletproof Coffee – has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ – a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement – it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey – and learn how to live longer, think faster, and perform better.

Copyright: © Copyright © Bulletproof Media 2023

Latest Episodes:

Up-level Your Approach to Food - Izabella Wentz : 571 Feb 28, 2019

Show notes

I care a lot about food, and I fundamentally think food is the single biggest tool you have to increase your performance, to change how you look, and to change how your brain works.

In this episode of Bulletproof Radio, I talk with Dr. Izabella Wentz, PharmD, an internationally acclaimed thyroid specialist and licensed pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto’s Thyroiditis in 2009. She also cares about food in the same way that I do. She developed the term “food pharmacology” to explain the profound effect that food has on our physiology and biology.

From her self-described “nerdy pharmacist” perspective, food works in ways similar to medication in the human body. She wants people to become their own food gurus and ask: “If I have this symptom, what do I need to modify? Is there a digestive enzyme that I need to take? Or is there a nutrient that can really up-level my response to nutrition?” Our conversation also touches on adaptive physiology, food sensitivities, mold and essential self-care.

She believes food can be a powerful ally in your healing journey. “My goal is to establish a communication pathway for people between their bodies and the things that they're ingesting,” she says.

As a patient advocate, researcher, clinician, educator and also a best-selling author of two previous books and a new one publishing in March, she is committed to raising awareness on how to overcome autoimmune thyroid disease, how to use food as medicine, and how to manage the stresses and toxins in our everyday environments.

Enjoy the show!

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Live and Die in L.A. with Neil Strauss : 570 Feb 26, 2019

Show notes

One of my favorite authors is back on the show! Neil Strauss is an award-winning, 10-time New York Times best-selling author. He was a music critic, cultural reporter, investigative journalist and columnist at The New York Times for a decade and has been a contributing editor at Rolling Stone for more than 20 years. He's well-known for earning the trust of some of the most guarded and secretive celebrities in the world.

His life has been enthralling and complex: Remarkably insightful interviews with celebrities and musicians, award-winning journalism, successful authorship and ghostwriting, becoming a pick-up artist, reforming himself and his relationships, becoming a parent and hosting programs focused on healing trauma and transforming lives.

In this episode of Bulletproof Radio, we talk about facing fears, discomfort and anxieties—how to tell the difference among them and what we get wrong about them. That leads us to a cognitive bias called the neglect of probability. As you may know, running from failure versus moving towards success is a very different mindset.

Neil shares his fascination with how beliefs get implanted and reinforced, and offers up a theory as to why so many people go off track when they're working on finding their passion and purpose. He says, “Do something you love enough that you care about each detail of it.” And that’s our cue to share some highlights of his intriguing new podcast—will it be called “’Gonzo?!”—that debuts this month.

Enjoy the show!

More about Neil Strauss

In addition to being an author of The Game, The Truth, Emergency and other books about his own personal experiences, he’s a respected and sought-after ghostwriter. He has co-authored numerous books, such as Jenna Jameson's How to Make Love Like a Porn Star; Mötley Crue’s, The Dirt (currently being produced by Netflix as a theatrical film); Marilyn Manson's The Long Hard Road; and Dave Navarro's Don't Try This at Home. Kevin Hart's I Can't Make This Up: Life Lessons, entered The New York Times bestseller list at No. 1 while topping the best-selling audiobook list at the same time.

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Biohacker News - Feb 2019 : 569 Feb 25, 2019

Show notes

Biohacking is the art and science of changing the environment around you, and inside of you, so you have full control of your own biology.

In this Episode, Dave tackles everything from scientists discovering a new way to grow neural stem cells from blood to hacking your brown fat to feel better, to the impacts of sleep on heart disease, to a claim that carbs are good for you, to diagnosing genetic orders with a selfie.

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Scientists Disrupt the Aging Game - James Peyer : 569 Feb 21, 2019

Show notes

James Peyer is the founder and managing partner of Apollo Ventures, an early stage life science investment fund investing in Europe and the U.S. focused exclusively on breakthrough therapeutics arising from the study of the biology of aging. Apollo founds companies with scientists, invests in early stage therapeutics projects, and works with scientific teams to build biotech companies. The company invests in core technologies that show promise in reversing aging and extending human lifespan.

“My whole group thinks of ourselves as scientists first and investors second, and so we really get super, super excited about a specific mechanism of action or a cool new way to develop a drug or a way to target aging,” James says. “That's kind of the hook that brings us into a project much more than some of the traditional financial metrics.”

He also gives talks all over the world on the topic of aging, discussing how our newfound knowledge of what makes us age will enable the greatest medical breakthroughs of the 21st century.

In this episode of Bulletproof Radio, we talk about what venture capital has to do with aging and why it matters that deep investments are being made in the arena of longevity. We touch on bio-freedom, as well as how working intentionally within a system can persuade skeptics and change the world. We cover a lot of ground, including the population effects of longevity, genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, altered intercellular communication, mitochondrial dysfunction and more.

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Meditation: The Ultimate High-Performance Tool— Emily Fletcher : 568 Feb 19, 2019

Show notes

Emily Fletcher is the founder of Ziva Meditation, the creator of The Ziva Technique that focuses on mindfulness, meditation and manifesting. She’s also created the world’s first online meditation training. Her work has been featured in national newspapers and magazines, as well as on television. She is regarded as a leading expert in meditation for high performance.

Her meditation journey began on Broadway and led her to India. Over the past decade, she has been named one of the top 100 women in wellness to watch, has taught more than 15,000 students around the world, and has spoken on meditation for performance at Google, Harvard Business School, Viacom and Wanderlust.

She’s taught Oscar, Grammy, Emmy and Tony award-winners, as well as NBA players, CEOs, entrepreneurs, and busy parents that meditation is a performance tool. The Ziva style is entertaining, accessible and easy to adopt.

In this episode of Bulletproof Radio, we talk about how releasing the stress from your past is essential and controlling your way through your life just doesn’t work. Meditation encompasses “the art and the beauty and the power of surrender.” And by manifesting—getting intentional about what you want your life to look like—you can consciously create a life you love.

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Tailor Your Brain’s Neurotransmission with Nutrients — William J. Walsh, Ph.D. : 567 Feb 14, 2019

Show notes

Dr. Bill Walsh is an international speaker on topics related to brain chemistry and behavior, learning, and mental health disorders. Over more than three decades as a research scientist and engineer, Dr. Walsh developed a science-based nutrient system that has helped thousands of people challenged by these disorders and is used by doctors throughout the world.

His approach recognizes that nutrient imbalances can alter brain levels of key neurotransmitters, disrupt gene expression of proteins and enzymes, and cripple the body’s protection against environmental toxins.

In this episode of Bulletproof Radio, we talk about Dr. Walsh’s exciting new research that includes significant developments in the areas of nutrient therapy and nutritional psychiatry, particularly Bipolar disorder. You’ll also learn the importance of the NMDA receptor and why antioxidant therapy is on its way to becoming mainstream.

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The Psychological Cost of Being Entertained - Lt. Col. Dave Grossman : 566 Feb 12, 2019

Show notes

Lieutenant Colonel Dave Grossman is a retired US Army Ranger and paratrooper, and a former West Point Psychology Professor. He is also the director of the Killology Research Group and actually developed the term “killology,” considered the study of the psychological and physiological effects of killing and combat on the human psyche.

Dave is an accomplished author who has published four novels, two children’s’ books, and six non-fiction books, which include his perennial bestseller On Killing.

Since his retirement from the US Army in 1998, he has been on the road almost 300 days a year for two decades as one of our nation’s leading trainers for military, law enforcement, mental health providers, and school safety organizations.

In this episode of Bulletproof Radio, we talk about developing a “bulletproof mind,” the effect that violent visual entertainment has on children, as well as ways to bulletproof your marriage and your kids.

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Understanding the Behaviour of Mitochondria - Martin Picard : 565 Feb 07, 2019

Show notes

Martin Picard, Ph.D. is an Assistant Professor of Behavioral Medicine in Psychiatry and Neurology at Columbia University. For over a decade, Martin has been studying mitochondria and has worked closely with leading experts in the field of mitochondrial research.

In 2015, he joined the faculty at Columbia University where he established the Mitochondrial Signaling Laboratory. He’s currently investigating mechanisms of mind-body interactions, specifically regarding novel principles that underlie mitochondrial responses to stressors, the maintenance of human health, and the influence of mitochondrial defects on complex cellular and physiological processes including aging.

In this episode, we talk about the exciting research happening in his lab and what mitochondria tell us about our health.

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What Medical Cannabis Can Do - Ricki Lake & Abby Epstein : 564 Feb 05, 2019

Show notes

On this episode, the guests are filmmakers Ricki Lake and Abby Epstein who, through their new movie "Weed the People" hope to help people make an informed choice. "Expanding people’s knowledge of something; having them be able to make a judgment and decision that’s best for them and their bodies.”

Ricki is someone you will likely know. She is a beloved pop-culture actress, had her own talk show for a dozen years, and now is a documentary filmmaker.

Abby is an award-winning director and producer of documentary films. The two have teamed up creatively for more than a decade to make films that inform, educate and portray incredible humanity.

I talk with them both about cannabis—and specifically about the use of it to help treat children’s cancer, which is the topic of their current documentary, “Weed the People.”

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How to Fall in Love With Your Work - Stella Grizont : 563 Jan 31, 2019

Show notes

Stella Grizont is a three-peat on the show who makes us all happier each time she is on. She is a speaker, executive coach, founder of WOOPAAH, and creator of The Work Happiness Method. She works with overachievers who are seeking deeper career fulfillment and with organizations who are dedicated to engaging their employees.

Stella is also one of the first 150 people to earn a master’s degree in Applied Positive Psychology (aka the science of happiness) from the University of Pennsylvania.

In this episode, you will find out how to fall in love with your work—whether it is where you are at right now or striking off in a new direction.

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