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    Health & Fitness

    Physionic

    I translate health studies for the public – from ‘the macro to the micro’.

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    Copyright: © Nicolas Verhoeven

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    Latest Episodes:
    Your Nutrition affects your Mitochondria (Fasting vs Overconsumption) [Study 32] Mar 03, 2022
    Show notes

    In this episode, we'll be diving into two ways your mitochondria change their "behavior" to the exposure to different nutrition situations (high vs low nutrient presence).
    Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure
    Video: https://www.youtube.com/watch?v=KQBmtzT4VTU
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6
    Study:
    Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
    Marc Liesa


    Saturated vs Unsaturated Fats: One is Worse for Insulin Resistance [Study 30] Feb 18, 2022
    Show notes

    In this episode, we'll be going over a new study that wanted to find out the effects a saturated fat heavy consumption would have on insulin resistance and signaling against an unsaturated fat heavy consumption.
    Video: https://youtu.be/QfII7CANt14
    Study: https://www.physionic.org/examine/%5Bs30%5D-dietary-palmitate-and-oleate-differently-modulate-insulin-sensitivity-in-human-skeletal-muscle
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6
    Sarabhai, T., Koliaki, C., Mastrototaro, L., Kahl, S., Pesta, D., Apostolopoulou, M., Wolkersdorfer, M., Bönner, A. C., Bobrov, P., Markgraf, D. F., Herder, C., & Roden, M. (2022). Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle. Diabetologia, 65(2), 301–314. https://doi.org/10.1007/s00125-021-05596-z


    Unsaturated Fat to the Rescue: Insulin Signaling and Mitochondrial Health [Study 28] Feb 10, 2022
    Show notes

    In this episode, we continue our quest for understanding the effect saturated fats have on muscle insulin signaling and mitochondrial health - however, beyond that, we'll be looking at how unsaturated fats may protect against the deleterious effects of saturated fat? Let's see..
    Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs28%5D-different-effects-of-oleate-vs.-palmitate-on-mitochondrial-function%2C-apoptosis%2C-and-insulin-signaling-in-l6-skeletal-muscle-cells%3A-role-of-oxidative-stress-
    Video: https://youtu.be/TiO16KoH0Fs
    Study Title: Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Larysa Yuzefovych


    Saturated Fat - Friend or Foe for Insulin Sensitivity and Mitochondrial Function? [Study 27] Feb 04, 2022
    Show notes

    In this episode, I'm kicking off a new format that's more tailored to the podcast listeners, so there's less need to head to the video versions of the podcast to understand half of what I'm talking about. In this episode, we'll be discussing saturated fat (palmitate) and it's effects in relation to insulin signaling in muscle cells, as well as mitochondrial function. What are the effects? What are the implications?
    Video: https://youtu.be/zMkV91E2Bic
    Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249685/


    Body Fat is lost from THIS - NOT HORMONES Nov 04, 2021
    Show notes

    In this episode, I attempt to make sense of calories in vs out and reconcile that with the hormone argument for fat loss.
    Video Podcast: https://youtu.be/x1ZjjDzCdc0
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6


    THIS is how Mitochondria DESTROY your Cells. Oct 28, 2021
    Show notes

    Mitochondria have a dark side, find out how.
    Video Podcast: https://www.youtube.com/watch?v=HPx7cv1I7eU
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6


    Long Term Effects from Fat Loss - Hormones, Weight Regain? [Study Breakdown] Oct 14, 2021
    Show notes

    In this podcast, we look at a study that investigates how weight loss affects hormones and long term weight regain - is the deck stacked against you?
    Study: https://www.nejm.org/doi/full/10.1056/nejmoa1105816
    Video Podcast: https://youtu.be/-t5d0S5MRwE
    0:00 - Introduction
    2:47 - Study Design
    6:58 - Weight Loss & Weight Regain Results
    9:45 - Long Term Hormonal Changes from Weight Loss
    34:12 - Conclusions/Take Aways
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6


    Does Intermittent Fasting, WITHOUT WEIGHT LOSS, improve your Health? [Study Breakdown] Oct 06, 2021
    Show notes

    How does intermittent fasting affect your health, even when you do not lose weight with it? Let's find out.
    Study: https://pubmed.ncbi.nlm.nih.gov/29754952/#:~:text=Men%20with%20Prediabetes-,Early%20Time%2DRestricted%20Feeding%20Improves%20Insulin%20Sensitivity%2C%20Blood%20Pressure%2C,Cell%20Metab.
    Video Podcast: https://youtu.be/1t0HUSlFNiQ
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6
    0:00 - Introduction
    3:23 - Study Design
    9:03 - Intermittent Fasting on Health Results
    18:24 - "Fasting Increases Inflammation"
    20:08 - Intermittent Fasting on Health Continued
    23:00 - Conclusions/Take Aways


    You asked for it: My Lifetime Workout Routine, Health Habits, and Supplements Sep 22, 2021
    Show notes

    Title says it all...
    Video Podcast: https://youtu.be/u4XirePJKfg
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6


    Sirtuins, Mitochondria, and Insulin Resistance Sep 15, 2021
    Show notes

    In this episode, we'll be discussing how sirtuins play their role in mitochondrial health and insulin resistance.
    Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432223/
    Video Podcast: https://youtu.be/M9INrzrfsu4
    0:00 - Introduction
    3:10 - Diabetes Background
    8:30 - Mitochondria Background
    13:33 - Mitochondria & Insulin Resistance
    20:33 - Sirtuins
    43:40 - Conclusions/Take Aways
    MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
    - 'Understanding Creatine' Book: https://bit.ly/31GxkSN
    - Hire Me: https://bit.ly/3dmUl2H
    - Content Requests: https://bit.ly/2QOVHLX
    SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
    - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
    - Facebook (Physionic): http://bit.ly/2PlIOaB
    - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs
    - Email List: http://bit.ly/2AXIzK6


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