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    Alternative Health

    Biohacking Beauty: The Anti-Aging Skincare Podcast

    Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond “single-molecule” trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ.

    We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.

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    Copyright: © Copyright 2026 Young Goose

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    Latest Episodes:
    NAD 101: Unlocking The Secrets To Youthful Skin Apr 12, 2024
    Show notes

    Are you currently using NAD in your skincare routine? As we age, the levels of NAD in our bodies naturally decline and play a factor in both decreased energy levels and more visible fine lines and wrinkles. The good news? You can make a major impact on your NAD levels with simple lifestyle changes like exercising regularly, eating a balanced diet rich in foods like fish and vegetables, as well as minimizing alcohol consumption.

    In this bonus episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, talks through what NAD is and why it should be utilized in your skincare routine. Amitay also discusses how UV external aggressors like UV rays, pollution, and blue light threaten to deplete our NDA and harm our DNA.


    Listen in as we learn that skincare and beauty are not just the foundation of outside appearances, but the ability to foster an internal, holistic, and healthy environment where your skin can thrive despite the challenges that may be posed by the outside world.


    What we discuss:

    (01:40) An introduction to NAD - the powerhouse molecule that has been a game changer for health, wellness and maintaining youthful, radiant skin

    (3:35) NAD and why environmental aggressors break down our skin, showing signs of aging

    (6:06) The impact of NAD in our expression of DNA and how it helps fuel enzymes to repair damage

    (8:18) DNA starvation causes dysfunction in the skin

    (11:19) How Young Goose is revolutionizing skincare through NAD

    (12:18) How serums and creams can protect and enhance your skin against environmental stressors

    (14:49) How the NDA molecule is broken down to be used in a lipid layer for skincare


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare



    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788



    Dr. Amy Killen: Resveratrol, Hyaluronic Acid, and Why All Supplements Aren't Created Equal Apr 10, 2024
    Show notes

    What would you do if all the essential vitamins you needed to hack aging were $438? Hopbox is revolutionizing health and wellness by stacking essential vitamins in one pack for you to consume, versus having to purchase hundreds of dollars worth of different vitamins. Changes to your vitamin intake can have long-lasting effects like better energy, deeper sleep, and even improvement in your metabolism due to increased mitochondrial production.

    In this episode of the Biohacking Beauty podcast, deep dive into the science of vitamins with Amitay, CEO of Young Goose, and Dr. Amy Killen, founder of Hopbox. Learn why not all supplements are created equal and why specific combinations of vitamins can impact our adaptability. Dr. Amy Killen draws connections between cellular care, radiant skin, and improved sexual health - all through daily supplementation.

    Start making deposits into your health and watch the dividends pay off in energy, metabolism, and skin health, as Amitay and Dr. Amy Killen connects the dots between cellular care and the holistic well-being of our bodies.


    What we discuss:

    (7:52) An introduction to Dr. Amy Killen and how her experiences led to biohacking

    (9:50) The Hot Box story: why quality ingredients matter

    (14:55) Investing in a better product for a better future you

    (17:46) Embracing your control mindset over aging

    (22:29) Resveratrol and how it may be overrated when it comes to antiaging

    (30:32) The Robin Hood vitamin, and how compounding vitamins can address various aspects of aging

    (42:17) How Hopbox can positively impact skin and sexual health

    (47:51) Supplements and their impact on essential lifestyle: sleep, exercise, and nutrition

    (52:41) Incorporating supplements into your daily routine for overarching skin health


    Dr. Killen is a leading regenerative medicine and longevity-focused physician. She is a clinical practice owner, educator, entrepreneur, and international speaker who focuses on aspects of health previously found at the margins - sexual health, skin health, hormones, longevity promoters, and stem cells.


    Dr. Killen is the founder of the Human Optimization Project (HOPBox.life) and is on the core team of Reputable.health.


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Dr. Amy Killen:

    Instagram:

    HopBox Life: https://hopbox.life/

    Use code YOUNGGOOSE for 20% OFF your first purchase.


    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Jean Fallacara: Health discoveries to hack aging and unlock the fountain of youth Apr 03, 2024
    Show notes

    Have you ever considered that no one solution or supplement can solve your potential health problems? The same is true even with your skin. Our biology is quite complex, and even within the biohacking space, we should consider that small changes can make a huge difference to our biology.

    In this episode of the Biohacking Beauty podcast, navigate through the cutting-edge intersection of neuroscience, fitness, and technology as Amitay, CEO of Young Goose, and Jean Fallacara discuss the secrets to beauty and longevity. Learn how brain optimization is essential to unlocking your potential and how you should establish a baseline of health before dabbling into advanced biohacking techniques.

    Amitay and Jean also discuss the future implications of biohacking and health technology with insights on wearable tech’s potential to truly aid the average consumers' perspective of their health and wellness by monitoring glucose levels in place of step counts, plus much more.


    What we discuss:

    (05:15) How biohacking can improve health and skin vitality

    (12:49) What extreme longevity looks like, and how early action to skin renewal can cause you to look more frail

    (18:11) Will manipulation of biology cause additional future health problems?

    (24:03) Peptides and Ozempic: the loss of ethics

    (29:27) Marketing weapons in the biohacking space

    (35:27) Being at peace without noise for the ultimate state of enlightenment

    (45:32) Glucose monitors the future of health tracking over fitness wearables

    (50:04) How life extension brings more wealth to the world

    (56:28) Skincare advice from a biohackers perspective




    Known as Cyborggainz, born in France, Jean Fallacara is a Serial Entrepreneur, Scientist, Athlete, Public Speaker, Art collector & Master of Endurance- Engineer in biotechnology with a specialization in virtual reality and augmented reality from MIT.


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Jean Fallacara:

    Website: https://jeanfallacara.com/

    Instagram: https://www.instagram.com/cyborggainz



    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Dr. Stephanie Estima: Understanding your hormones and their connection to your health Mar 27, 2024
    Show notes

    Did you know that as a woman your body’s receptiveness to fitness fluctuates based on your menstrual cycle? According to Dr. Stephanie Estima, women should look at their monthly cycle as a report card for health, using the cycle to make informed choices that resonate with the bodies' natural rhythms.

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, discusses the holistic view on women’s health and fitness and the impact that it has on aging with Dr. Stephanie Estima. Listen in as they unpack the benefits of aligning self-care practices with hormonal fluctuations, and learn why the right timing can make all the difference in achieving peak performance and beauty,

    Dr. Stephanie Estima is a doctor of chiropractic with a special interest in metabolism, body composition, functional neurology, and female physiology. She's been featured on Thrive Global, of the Huffington Post, has over 3.5 million article reads on Medium.com, and has helped thousands of women lose weight, regulate hormones, and get off medications with her signature program, The Estima Diet. You can hear her every week on her podcast, Better! With Dr. Stephanie.


    What we discuss:

    (00:06) How your metabolism can impact your skin wellness

    (12:17) Uncover the misconceptions about health and fitness, and why your cycle is a report card

    (20:26) How your skincare and workout routines should be synchronized with your menstrual cycle

    (32:05) Muscle building, and unexpected benefits for females when they focus on maintaining strength

    (44:06) Why strength training is crucial for individuals in their late 40s, 50s, and 60s

    (53:26) Discover how the connection between sugar consumption can affect skin elasticity and collagen production

    (1:07:00) The minimum amount of protein needed per pound of ideal body weight

    (01:12:41) How the body uses amino acids to repair and create new tissue, while also providing a number of additional benefits




    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Stephanie Estima:

    Website: https://hellobetty.club/

    Instagram: https://www.instagram.com/dr.stephanie.estima/?hl=en

    Podcast: https://hellobetty.club/podcast


    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Joe Cohen: How autoimmune struggles lead to optimal health through biohacking Mar 20, 2024
    Show notes

    Is genetic testing a future key indicator for achieving optimal skin health? With the emergence of cutting-edge software, we now can minimize the guesswork regarding our generic insights. However, it is not a foolproof system… yet, as there is a vital difference between data-driven health solutions and faulty tests.

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, catches up with Joe Cohen, the founder of Self Decode, to discuss the evolution of personal health optimization through data analysis and technology. Hear from Joe as he recounts his own experiences with self-experimentation and how it paved the way for improved health.

    Listen as Amitay and Joe discuss the intricacies of genetic testing and metabolomics, as well as how important real-time data can craft individualized health strategies. Joe Cohen is recognized as a biohacker and entrepreneur who has helped over 150,000+ customers achieve optimal health using the most advanced genetic analysis.

    What we discuss:

    (1:30) Growing up with health problems and biohacking

    (15:22) Experimenting with your health and trusting the data

    (23:23) What is Self Decode and how it can help identify opportunities in your health

    (31:49) The snipping of genetic code and why you should proceed with caution

    (37:02) Why supplements are not the answer to your health problems

    (43:50) The dimensions of mapping your goals and using genetic testing to achieve them

    (53:38) How genetic testing can impact skin health

    (1:06:57) Metabolomics and amino acids, and the role they play in your health

    (1:19:12) Health education and the gap within the healthcare system

    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Joe Cohen:

    Instagram: https://www.instagram.com/mrbiohacker/?hl=en

    Self Decode: https://selfdecode.com/?utm_source=Instagram&utm_medium=joe_social&utm_campaign=linkinbio&nab=1&utm_referrer=https%3A%2F%2Flinktr.ee%2F



    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Jodi Duval: NAD+, Skincare Science + The Future of Skincare Mar 13, 2024
    Show notes

    Did you know that the skincare you are using may be providing you with results, while harming the other systems in your body? Biohacking skincare is a holistic and proactive way to optimize skin health and appearance through personalized experimentation.

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, connects with Jodi Duval to discuss the Young Goose story and how leveraging scientific research and innovative techniques can lead to achieving desired results from your daily skincare routine. Explore the key ingredients that make Young Goose unique in the skincare industry, as well as Amitay’s recommendations for what mechanisms are revolutionizing skincare.

    Jodi Duval is a naturopathic physician and CEO of HOMeHOPe, a nonprofit organization teaching doctors and practitioners a foundational approach to health.

    What we discuss:

    (01:21) The story of Young Goose and importance of biohacking skincare

    (09:43) The importance of the skincare results you want without harming other systems in the body

    (21:42) Defining the hallmarks of aging, and how key ingredients play a role in skin maintenance

    (33:33) The impact of peptides on the skin

    (44:55) Resolving skin trauma, and the impact that trauma can have on the skin

    (58:36) The negative effects of chemical sunscreen on skin and why you should avoid it

    (1:08:12) The power of quality ingredients to fuel the skin

    (1:15:16) The world's strongest antioxidant that rebuilds your skin barrier, and how Young Goose is biohacking it

    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare

    To learn more about Jodi Duval:

    Instagram: https://www.instagram.com/jodi.duval/

    Website: https://homehope.org/

    Podcast: Revital Health


    Dr. Cameron Chesnut: Injectables, Plastic Surgery, Non-Invasive Cosmetics + The Ice Bath Approach for a Younger Appearance Mar 06, 2024
    Show notes

    Did you realize that subtle cosmetic enhancements through plastic surgery can aid in facial rejuvenation? Embracing a holistic approach to plastic surgery yields more natural and long-lasting results while also reducing recovery time and extending the efficacy of the procedure.

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, sits down with Dr. Cameron Chesnut to explore how minimally invasive cosmetic enhancements can achieve facial rejuvenation. We delve into the notion of 'perception drift' concerning facial fillers and underscore the significance of striking a balance between surgical and non-surgical interventions.

    Dr. Cameron Chesnut is recognized worldwide as a key opinion leader and innovator in both minimally invasive and non-surgical cosmetic procedures. His training background is uniquely cross-pollinated with integrated fellowship training in facial plastic surgery, oculoplastic surgery, dermatologic surgery and general plastic surgery.

    What we discuss:

    (0:36) A holistic approach to plastic surgery to benefit consumers.

    (5:57) The classification of qualitative (non-invasive procedures) and quantitative (invasive procedures.

    (8:50) Proactive plastic surgery to lengthen results through aging.

    (16:41) The impact of injectors and easy go-to cosmetic procedures on aging, and how injectors can change the movement within the face over time.

    (35:15) How overall functional health impacts the quality and longevity of surgical procedures.

    (46:40) The future of plastic surgery and redefining anti-aging through more minimally invasive surgeries.

    (53:54) A holistic approach to health to positively impact your skin and appearance, with key daily practices to be conductive to anti-aging.


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Dr. Cameron Chesnut:

    Instagram: https://www.instagram.com/chesnut.md/

    Website: https://www.clinic5c.com/


    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Mark Young: Secrets to Ageless Skin & a Thriving Life Feb 28, 2024
    Show notes

    Ageless beauty is not an elusive concept reserved for the chosen few with perfect genetics or those who follow strict diets. It is accessible to everyone who is willing to listen to their body, respect its needs, and embrace a holistic approach to health that includes mind, body, and spirit. It's about the synergy of lifestyle choices, from what we eat to how we move, and how we manage stress and environmental factors.

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, is joined by Mark Young, CEO of Rise Agency, to discuss the importance of taking a holistic approach to health and beauty. We discuss the role of personal health narratives and lifestyle choices in wellness and beauty and the intricacies of genetics, diet, and lifestyle on skin health.


    Mark Young, CEO of Rise Agency, is an entrepreneur, educator, author, and philanthropist noted for his explorations in marketing for biohacking and health optimization. His story is a testament to his drive for self-improvement and his dedication to understanding the correlation between lifestyle and health.


    What we discuss:

    (0:02:06) - The intersection of professional and personal dedication to wellness and aesthetics, including the role of biohacking and health optimization.


    (0:14:07) - The holistic approach to health, diet, detoxification, exercise myths, and the interconnectedness of bodily systems for preserving youth.


    (0:23:47) - Reflection on the philosophy of striving for excellence, the importance of commitment, setting challenging goals, and the concept of "active meditation" for personal growth.


    (0:32:59) - The significance of genetics, skincare, nutrition, and environmental factors on skin health, and the importance of foundational health practices.


    (0:46:21) - Addressing a listener's question about Profhilo, a hyaluronic acid-based skin treatment, and discussing skin biochemistry, the importance of treatment purity and safety, and patient awareness.


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Mark Young:

    Instagram: https://www.instagram.com/themarkyoung/

    Website: https://www.ryzeagency.com/


    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Don Moxley: Using Spermidine to Reverse Skin Aging Feb 21, 2024
    Show notes

    Spermidine plays a powerful role in our health and longevity, but why should we integrate it into our skincare routine to achieve a radiant, youthful glow?

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, is joined by Don Moxley, an expert in longevity and performance optimization, who dives into the benefits of spermidine, a polyamine compound. This exceptional ingredient enhances both internal health and external beauty, providing a holistic approach to skincare that is both revolutionary and deeply rooted in the science of cellular regeneration.

    We discuss the potency of spermidine, which enhances cellular function and combats skin aging in a fusion of regenerative medicine principles and modern skincare. We also underscore the significance of maintaining a balanced lifestyle for optimal skin health, including the ways in which resilience-building and mindful choices can mirror the benefits of an effective skincare routine. Finally, we explore the world of personalized skincare and topical applications as means to enhance beauty and health, emphasizing the importance of finding a balance between internal and external approaches for optimal efficacy and radiance.


    Don Moxley is an exercise physiologist and Director of Applied Science and Brand Development at Longevity Labs, a nutritional supplement company founded in Austria. Their flagship product is SpermidineLife, a daily nutritional supplement that has been shown to trigger a key element of longevity, autophagy.


    What we discuss:

    (0:02:07) - How aging is a multifaceted process and the introduction of Young Goose’s new skincare products with spermidine


    (0:14:24) - The layered approach to aging and beauty and how incremental lifestyle changes help with resilience


    (0:22:55) - Spermidine's properties, the concept of the entourage effect, and the importance of spermidine in skincare


    (0:36:44) - Stress, perspective, and healthy living, and the importance of marginal techniques for extending life and the interconnectedness of mind and body


    (0:43:09) - The transformative power of cellular care in skin aging, regenerative medicine, and the role of spermidine in cellular maintenance and skin health.


    (0:58:09) - The impact of spermidine on cellular health and the importance of timing in supplementation, especially for individuals over 50


    (1:01:39) - Addressing aesthetic procedures and the importance of considering both internal and external factors


    (1:17:00) - Q&A on managing rosacea, gut health, and the effects of radiofrequency treatments like Morpheus 8 on skin texture and collagen production


    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Don Moxley:

    LinkedIn: https://www.linkedin.com/in/donmoxley/

    Instagram: https://www.instagram.com/spermidinelife.us/

    Website: https://spermidinelife.us/


    Resources:

    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Alyssa Blue: Anti-Aging Benefits of PEMF (+ for Your Skin!) Feb 14, 2024
    Show notes

    There's no denying the profound impact technology can have on our health and wellness, but can it really merge with ancient healing practices to optimize our well-being?

    In this episode of the Biohacking Beauty podcast, Amitay, CEO of Young Goose, is joined by Alyssa Blue, an aerospace engineer turned wellness innovator, shares how she is aiming to achieve this with her groundbreaking Align Mat. This innovative tool marries the benefits of modern technology with the healing properties of Earth's natural frequencies, providing a holistic approach to wellness that is both revolutionary and deeply rooted in time-tested wisdom.


    We discuss the Align Mat, which combines PEMF therapy and far-infrared heat in a blend of ancient healing practices and modern technology. We also explore the importance of maintaining a connection with nature for optimal health, including the ways in which technology like the Align Mat can replicate the benefits of natural environments. Finally, we delve into the world of biohacking and PEMF therapy as means to enhance human performance and health, underlining the necessity of finding a balance between low-intensity and high-intensity treatments for optimal safety and efficacy.


    Alyssa Blue is a Functional Diagnostic Nutrition Practitioner and cofounder of LYFEH2O water systems & ALIGN Quantum Mat.


    What we discuss:

    (0:02:08) - Alyssa Blue's transition from aerospace engineering to wellness innovation and the introduction of the Align Mat with PEMF therapy and far infrared heat.


    (0:14:47) - The complex relationship between humans and nature, and the healing effects of the Schumann resonance on our well-being.


    (0:19:51) - The role of biohacking and PEMF therapy in enhancing human performance, and the benefits for pain reduction, wound healing, and relaxation.


    (0:28:59) - Using PEMF therapy mats with adjustable hertz settings for both elite athletes and individuals with chronic inflammation, and the importance of natural frequencies.


    (0:38:27) - The multifaceted benefits of using a PEMF mat, setting your vibrational frequency, and the importance of taking a moment for oneself.


    (0:51:19) - Low vs high-intensity healing devices, safety concerns, and the cumulative benefits of gentle frequencies.


    (0:55:48) - Pain management, skin health, and the need for medical clearance when using extremely low-frequency devices for specific populations.


    (1:01:21) - Causes of premature skin aging, the significance of skin type and consistency in using anti-aging products, and holistic health practices to support skin health.



    To learn more about Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    To learn more about Alyssa Blue:

    Instagram: https://www.instagram.com/myalignmat/

    Website: https://myalignmat.com/


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