The Melanie Avalon Biohacking Podcast

Latest Episodes:

#099 - Dr. Robert Lustig: Secrets Of The Food Industry, Processed & Ultra Processed Foods, The Hazard Of Added Sugar, Mitochondrial Dysfunction, Metabolic Disease, Whole Food As Medicine, And More! Jun 24, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/metabolical 2:10 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:20 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 8:10 - Dr. Lustig's Background 10:10 - What Is Processed Food? 12:40 - The Nova System (Classes Of Processing) 14:45 - Class 4 Ultra Processed Food 16:50 - The Diet Debate 18:20 - Leaky Gut 19:25 - Could The Microbiome Adapt To Processed Food? 23:55 - What's Better: Quality Food Or Fasting? 28:10 - NAFLD 29:40 - Liver Fat & Metabolic Disease 32:40 - Visceral Fat And Clinical Depression 34:40 - Burning Liver Fat With Fasting 37:20 - Which Comes First: Insulin Resistance Or Weight Gain? 42:40 - Overproducing Insulin And Blocking Leptin 43:50 - The Role Of Personal Responsibility 46:10 - De Novo Lipogenesis With Carb Intake 46:55 - The Role Of Choline 47:55 - Is Over-Processing Food A Moral Hazard 50:30 - Health Insurance 51:10 - The Immoral Hazard 51:50 - Commercialization Of Organics And Whole Food 54:05 - Pesticides 54:45 - Labeling Processed Foods As Toxic 57:45 - The Real Disease; The 8 Pathologies 1:00:35 - Low Fiber High Sugar 1:01:20 - Fixing The Problem 1:03:20 - Research With Fiber And CGM 1:04:35 - UCSF Soda Ban 1:06:40 - Expanding The Soda Ban 1:07:45 - GRAS List 1:10:15 - Removing Items From The GRAS List 1:11:40 - Addictive Food robertlustig.com metabolical.com
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#098 - Dr. Will Cole: Intuitive Fasting, Intuitive Eating, Toxic Diet Culture Food Peace, Mindfulness In The Body, Metabolic Flexibility, The Power Of The Microbiome, And More! Jun 17, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/intuitivefasting 2:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 3:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 8:40 - Will's Background 12:30 - The Controversy 15:25 - The Problems With Intuitive Eating 19:10 - The Insulin Resistance Inflammation Spectrum 23:50 - Can You Intuitively Eat Processed Foods? 25:00 - Who Is Intuitive Eating/Fasting For? 27:40 - Gaining Metabolic Flexibility 29:05 - Healthy Control And Food Peace 30:50 - The Evolution Of Fasting In Culture 31:20 - How Does Fasting Become Intuitive? 34:00 - Using Food And Fasting As A Mindfulness Practice 36:25 - Teaching Intuitiveness 39:00 - Fasting In Spiritual Tradition 41:00 - What Is Required For Change In Our Culture? 46:00 - Transparency In Industry 46:35 - Plant-Based Vs Animal Inclusive Diets And Food Labeling 54:00 - Nutritional Ketosis 55:25 - Being Able To Pivot And Being Comfortable In Evolving 57:45 - The Power Of The Microbiome 59:40 - Intestinal Gluconeogenesis 1:03:00 - Tea 1:07:30 - Tea's Effect On Insulin
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#097 - Dr. Terry Wahls: The Wahls Protocol, Mitochondrial Dysfunction, Neuromuscular Electrical Stimulation, Reversing Neurological Disorders, Healing The Myelin Sheath, And More! Jun 10, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/wahls 2:00 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 7:30 - Dr. Whals' Story 11:30 - Multiple Sclerosis 14:15 - Myelin and Mitochondria 15:05 - Myelin Dysfunction 15:50 - Mitochondrial Strain In Autoimmune Diseases 17:35 - Supplement Support 20:30 - Electrical Stimulation For Muscle Growth 23:40 - Muscle Atrophy In MS 24:05 - The Shift Of Metabolism 24:50 - Diseases Of Insulin In MS Patients 27:20 - Insulin Sensitivity In Astronauts 29:20 - Neuromuscular Electrical Stimulation Devices 30:05 - E-Stim In Athletes 31:45 - E-Stim In Bed Ridden Patients 32:50 - Recovery With The Paleo Diet And Lifestyle 40:25 - Clinical Trials On The Diet Protocol 47:05 - Healing The Myelin 49:40 - Remineralizing Teeth 52:00 - The Timeline Of Accepting New Concepts In Science 55:15 - Proving The Wahls Protocol 56:50 - The Early Adopters 57:45 - The Importance Of Being Strict For The First 100 Days 59:10 - Accidently Triggering New Autoimmune Disease 1:02:40 - Working As A Family 1:03:00 - Terry's Current Protocol 1:05:05 - Longevity Genes
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#096 - Casey Means, MD (Levels): Continuous Glucose Monitors, Blood Sugar And Inflammation, Insulin Resistance, Metabolic Fitness, Healthy Blood Sugar Ranges, Diabetes Prevention, And More! Jun 03, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/levels Skip The (115,000 person!) Waitlist By Going To Melanieavalon.Com/LevelsCGM With The Coupon Code MelanieAvalon! 2:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 9:25 - Casey's Background 14:20 - What Is A CGM? 20:50 - What Is The Levels Experience Like? 21:20 - How Is The Prescription Accessible? 23:10 - The Application Process 25:15 - What Is It Measuring? 26:20 - What Is Insulin's Role In The Interstitial Fluid? 27:15 - How Accurate Is It? 28:40 - The Highest Saturation Levels 30:15 - CGM Compared To A Finger Prick And/Or A Lab Draw 31:30 - Why The 14 Day Time Limit? 33:00 - Recommendations For Placement 35:20 - Placing A Patch Over The Sensor 35:50 - Night-Time Accuracy 40:45 - What Is A Good Range? 48:10 - CRP (C-Reactive Protein) And Inflammation 50:00 - The Negative Effects Of Glycation 51:20 - Insulin Resistance 53:30 - Metabolic Fitness 54:40 - The Most Insulinogenic Foods 55:50 - The "Area Under The Curve" 1:00:00 - Reactive Hypoglycemia 1:02:35 - How To Bring Back Carbs After HFLC 1:10:15 - The Differences In Glucose Response Person To Person 1:11:50 - Glucose Levels In A Diabetic Individual 1:12:35 - The Influences On Insulin Resistance 1:16:15 - Berberine 1:16:50 - Glucose-Lowering Probiotics 1:18:50 - Is 2 Weeks Enough Time To Learn Your Patterns? 1:21:50 - Can Listeners Subscribe To Levels? 1:23:30 - Using The App And The Zone Score 1:27:00 - How The Zone Score Is Valuated 1:28:10 - Updates To The App 1:28:45 - Data Storage Of The Sensor 1:31:00 - Calibration 1:31:20 - The Bluetooth And EMF 1:31:50 - The Difference Between Glucose Levels, HbA1c And Serum Fructosamine 1:37:20 - Testing Gestational Diabetes Skip The (115,000 person!) Waitlist By Going To Melanieavalon.com/LevelsCGM With The Coupon Code MelanieAvalon!
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#095 - Jonathan Bailor: Body Weight Setpoint, Burning Calories, Food Quality, Obesity & Diabetes Epidemic, Brain Inflammation, Hormonal Dysregulation & Gut Dysbiosis, The SANE Solution, And More! May 27, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/setpoint 1:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 6:40 - Jonathan's Personal History 11:35 - Why Do People Gain Or Lose Weight? 13:10 - The Global Economic Impact Of Diabetes 14:50 - What Happens With Calories That We Eat? 16:45 - The Calorie Is A Measure Of Energy Alone 18:00 - Why Does The Body Burn Or Store Calories? 19:50 - Dietary Induced Thermogenesis 20:00 - N.E.A.T. (Non-Exercise Activity Thermogenesis) 23:20 - Perceived Rate Of Exertion 24:20 - Eat Less, Move Less 24:30 - What Is The Stress Response To A Crash Diet? 25:10 - Long Term Outcomes Of Crash Dieting 26:15 - Yo-Yo Dieting And The Extracellular Matrix 27:00 - Defining The "Set Point" 29:55 - How Do We Get Our Set Point? How Does It Change? 33:00 - Obesity As A Disease State 34:00 - The Quality Of The Food We Eat 35:00 - The Overconsumption Of Food 36:40 - Hormone "Clogging" 39:35 - Parabiotic Studies 40:45 - The Communication Between Brain, Gut, And Hormones 43:40 - The Genetic Component 47;55 - The Pervasive Shame In Being "Over-Fat" In Society 48:30 - SANESolution 50:25 - Evaluating Foods On A Spectrum For Optimal Health 52:10 - The SANE Food Groups 55:30 - What About Lower Fat Or Lower Carb? 57:05 - Metabolic Conditioning 59:10 - The Randall Cycle 59:25 - The Myth Of Exercise 1:02:50 - Mechanical Removal Of Fat Cells
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#094 - Marty Kendall: Big Fat Keto Lies, Energy Toxicity & Insulin Toxicity, Diabetes, Burning Fat In the Krebs Cycle, The Obesity Epidemic, Data Driven Fasting, Nutrient Density & Satiety, And More! May 20, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/ketolies 2:30 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:45 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 8:00 - Marty's Personal Story 9:55 - Misconceptions Around Controlling Diabetes 11:55 - Insulin's Role In Each Type of Diabetes 13:45 - Understanding The Lack Of Insulin: T1D Vs. T2D 14:30 - Diabulimia 15:44 - Basal Insulin 16:25 - Insulin In Fat Storage And Release 17:15 - Insulin Is Anti-Catabolic 18:30 - Non-Insulin Mediated Glucose Uptake 19:00 - The Role Of Insulin In Fat Storage 19:40 - Oxidative Priority 20:55 - Does Fat Illicit A Fat Response? 22:05 - Can You Take In Too Much Fat? 23:50 - More Fat Over The Long Term Leads To More Insulin 24:50 - Burning The Energy In Your Body 26:55 - Consuming Bulletproof Coffee And MCT Oil, Etc 28:40 - Experiments With C8 MCT 31:05 - Factors That Effect Fatty Acid Esterification 32:00 - The Idea Of Burning Fat Exclusively In The Absence Of Carbs 34:00 - Burning Fat In The Krebs Cycle 33:30 - Energy Toxicity And Ketone Levels 39:00 - Is Burning Ketones "Cleaner"? 39:40 - The Different Types Of Ketones 45:50 - Low Glucose And High Breath Ketones 47:00 - Nutritional Ketosis 51:20 - The Real Goal Of Low Carb Diets 52:25 - Charts Of Energy Distribution 54:20 - Long Term Fasting 55:10 - What Has Caused The Obesity Epidemic? 57:00 - Lack Of Nutrient Density In Our Food System 59:00 - The Bliss Point Of Fake Foods 1:00:45 - Satiety 1:02:00 - MUFA, PUFA, And Saturated Fat Satiety 1:03:40 - Omega 3 Satiety 1:06:45 - Micronutrient And Macronutrient Satiety Index 1:08:25 - The Triage Theory 1:09:15 - Is It Possible To Get All Nutrients From The Diet? 1:25:35 - Taking Concentrated Supplements 1:13:05 - Are Animal Products Less Depleted Of Nutrients? 1:16:10 - Regenerative Agriculture 1:17:20 - Vegan Vs. Carnivore 1:18:50 - Carnivore As An Elimination Diet 1:21:35 - High Blood Sugar In Keto And Carnivore 1:22:35 - Gluconeogenesis Driving Insulin Resistance 1:26:40 - Elevated Glucose Due To Gluconeogenesis 1:27:45 - Chicken Or The Egg? Is Insulin Resistance Or Obesity First? 1:28:15 - Insulin Resistance In Thin People Vs Obese People 1:30:10 - Insulin Response From Food 1:31:45 - Seasonal Eating 1:34:45 - Checking Glucose Before Eating 1:37:40 - Blood Sugar SetPoint 1:38:40 - Eating With High Blood Glucose; A Hack 1:39:40 - Using Berberine 1:39:55 - Alcohol 1:41:50 - Biggest Lesson 1:43:20 - Data-Driven Fasting 1:45:20 - Macros, Calories, And Nutrients
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#093 - Shawn Wells: Quality Supplements, Berberine, Resveratrol, CBD, NMN, New Biohacking Compounds, Polyphenols & Adaptogens, Whole Foods Vs. Supplementation, Ketogenic Diets & Fasting, And More! May 13, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/energyformula 2:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:10 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 8:25 - Shawn's Beginnings 14:00 - Orthorexia 16:00 - The Role Of Fear In Health 21:40 - Being A Bio-Hacktivist 24:25 - The Relationship With Biohacking And Supplements 25:25 - Bad Supplements On The Market 27:35 - Is There Any Type Of Certification? 32:00 - How Are Vitamins And Supplements Made? 35:20 - What About Transdermal Patches? 38:15 - NMN Vs NR 38:00 - Intranasal Application 41:10 - Glutathione Supplementation 42:35 - L-Ergothioneine 44:10 - The Power Of Mushrooms 44:55 - Taking Exogenous Antioxidants; Vitamin C 47:00 - Polyphenols And Xenohormesis 49:40 - Whole Food Vs Supplements 53:20 - CBD 56:00 - Isolated Vs Full Spectrum CBD 57:00 - Powdered Processed Foods 59:20 - Whey Protein 1:00:30 - Collagen 1:02:20 - Importance Of Amino Acid Ratios 1:04:10 - Glycine 1:06:00 - What Is CD38? 1:08:20 - Berberine 1:10:30 - Berberine's Anti-Viral Properties 1:19:20 - How Do You Know If Your Supplements Are Effective? 1:22:55 - Shawn's Top Picks 1:24:15 - Thoughts On Breaking A Fast 1:29:10 - Exogenous Ketones; RBHB Sodium 1:31:45 - MCTs 1:35:40 - BAIBA 1:37:45 - Anandamide 1:41:45 - Dehydrozingerone 1:45:10 - Nucleotides 1:46:10 - Tetrahydrocurcumin 1:50:00 - Raspberry Ketones
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#092 - Dr. Steven Gundry: The Energy Paradox, The Chronic Fatigue Cause, Mastering Your Mitochondria, Energy Generation, Prebiotics, Probiotics, & Postbiotics, Healing Leaky Gut, And More! May 06, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/energyparadox 2:15 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:30 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon At Facebook.com/groups/cleanbeautymelanieavalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter, And Safe Skincare! 8:30 - The Energy Paradox: The Beginning 10:15 - Fatigue & Malaise 11:15 - The Myths Surrounding Fatigue 12:25 - Adrenal Resistance 14:30 - Cellular Energy Crisis; How Do We Generate Energy 20:25 - Coupling In ATP 21:45 - The Warburg Effect 23:10 - The Origin Of Mitochondrial DNA 27:25 - What Is The Mitochondria's Preferred Fuel? 30:00 - Processed And Ultra Processed Foods 31:30 - Fuel Processing In The Mitochondria 32:25 - Mono-Diets 34:40 - Failing At Mono-Diets 35:20 - The Drinking Man's Diet 36:35 - The Ketogenic Diet 41:00 - Postbiotics 43:15 - Hydrogen Sulfide 47:00 - Deuterium Depleted Water 48:40 - Gas In The Gut Vs The Blood 50:00 - Damage To The Gut & Autoimmune Disorders 51:35 - Antibiotic Usage 52:50 - Glyphosate 54:55 - Plant-Based Meat Products 55:30 - Vitamin D Deficiency 56:10 - UVB Exposure From Tanning Beds 57:10 - The Hadza Energy Paradox 1:04:00 - Inflammation And Overwhelming The Mitochondria 1:05:25 - Percentage Of Energy Need Met By Ketones 1:06:00 - Exogenous Vs Endogenous Fuel 1:08:00 - Free Fatty Acids Converting To Ketones 1:10:45 - Studying Calorie Restriction And Longevity 1:15:50 - The Benefit Of A Short Eating Window 1:17:40 - The Literature On Lectins
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#091 - Melanie Dale: Calm The H*ck Down, Managing Your Sanity, Raising Kids, Expectations Vs. Reality, Instilling Honesty And Integrity, Responsibility With Social Media, And More! Apr 29, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/parenting 2:30 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:40 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon At Facebook.com/groups/cleanbeautymelanieavalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter, And Safe Skincare! 10:00 - Melanie's Background 13:00 - Focusing On The Mindset Of Parenthood 14:00 - Expectations Vs Reality 15:40 - Non-Negotiables And Places Where You Can Give In A Little 16:30 - Parenting In A Pandemic 17:50 - Parenting Styles For Different Kids 19:25 - Age Appropriate Chores And Independent Activities 25:30 - Teaching With Movies 28:15 - Kids And Social Media 34:15 - Setting Rules 35:35 - The Importance Of Honesty 38:25 - How To Stay Calm When You're Overwhelmed 39:45 - G.R.A.C.E: Gratitude, Read, Adapt, Create, Engage, & The Value Of Laughter 45:00 - The Story Of The Stolen Golf Cart 47:55 - How To React When Your Child Is Attention Seeking 51:50 - The Role Of Therapists For Parent And Child 55:30 - Body Image And Insecurity 59:50 - Food, Diet, And Eating 1:06:15 - Kids & Bedtime Go To BluBlox.com And Use The Code melanieavalon For 15% Off! 1:11:10 - Working Parents 1:14:30 - Religion And Spirituality
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#090 - Shawn Stevenson: Microbiome Mysteries, The Natural Human Diet, Food Sensitivities, Dietary Fat & Burning Body Fat, Environmental Toxins, Gut Dysbiosis, And More! Apr 22, 2021

Show notes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/eatsmarter 1:45 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon At Facebook.com/groups/cleanbeautymelanieavalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare! 7:50 - Shawn's Background 9:20 - Unique Metabolic Protocols 12:10 - Empowering Patients 13:20 - Clinical Trial To Clinical Practice 16:20 - Deciphering The Science Literature 16:55 - The Microbiome, Diet & Metabolism 19:20 - The Prevalence Of Statins 20:00 - Statins And Diabetes 21:55 - The Microbiome Of Obesity And Leanness 25:30 - Pesticides Effect On Microbiome 30:25 - Probiotics 33:20 - The Human Immune System 35:25 - Epigenetics And The Microbiome 38:30 - Obesity In America 39:50 - Adapting To A Change In Diet 40:50 - Microbes And Longevity 43:05 - Prebiotics 44:00 - Improving The Microbiome Diversity 44:30 - Weight Regain And Other Symptoms 45:15 - The Microbiome Of Real Food 46:00 - "Post"-Biotics 46:30 - Washing Fruit And Vegetables 47:30 - Exposure To Pesticides 49:20 - Pesticides And Environmental Toxins In Food 50:40 - The Immune System In Your Gut 52:10 - Grains In The Human Diet 54:10 - Gluten And Leptin Resistance 56:10 - Gluten Crossing The Gut Barrier 57:30 - Creating Dysbiosis By Accident 1:01:10 - Food Sensitives 1:03:20 - Sprouting To Reduce Antinutrients 1:06:30 - Food Becoming Fat, And Burning Fat 1:09:20 - The Need To Rename Dietary Fat 1:11:00 - Subcutaneous Fat 1:12:45 - Visceral Fat 1:14:05 - Intramuscular Fat 1:15:40 - Structural Fats 1:15:40 - Brown Adipose Tissue (BAT) 1:16:50 - Beige Adipose Tissue 1:19:20 - Does Keto Increase Intramuscular Fat? 1:20:15 - The Quality Of The Macronutrients 1:21:00 - Do Fat Cells Want To Be Full? 1:23:30 - Resiliency Of Fat Cells 1:26:00 - The Role Of Hunger And Calories In Over-Restriction
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