The DUTCH Podcast

Latest Episodes:

The Estrogen Myth: Rethinking Hormone Therapy & Breast Cancer Risk May 12, 2026

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Join us for this episode with Dr. Jenn Simmons, an integrative breast surgeon and oncologist, alongside host Dr. Jaclyn Smeaton and DUTCH founder Mark Newman. This conversation deepens the discussion from a previous episode on hormones and breast cancer risk, challenging widely held clinical assumptions rooted in the Women's Health Initiative (WHI) study.

This episode also explores:

The critical distinction between progestins and progesterone
The role of metabolic dysfunction in cancer development
Breast cancer as a disease of hormone deficiency, particularly progesterone deficiency, rather than hormone excess
The impact of estrogen metabolism, especially the 4-hydroxy pathway, and how the DUTCH Test can provide insight into these pathways
Individualized hormone therapy for breast cancer survivors

Show Notes

Listen to our previous episode with Dr. Jenn Simmons!

Check out the aging human breast study, the study on menopausal hormone therapy after breast cancer, and the transdermal testosterone study mentioned in this episode.

Learn more about Dr. Jenn Simmons and follow her on Instagram @drjennsimmons!

Become a DUTCH Provider to get access to comprehensive patient reports, peer-reviewed and validated research, and expert clinical support.

How Estrogen Shapes Women’s Health & Longevity May 05, 2026

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In this episode, Dr. Asare Christian and Dr. Jaclyn Smeaton discuss female longevity and health span. Dr. Christian brings his unique perspective as a former pain specialist who discovered that many of the chronic conditions he was treating were rooted in hormone imbalance.

This episode also highlights:

· Three main factors that can contribute to women living longer

· The protective qualities of estrogen as well as the effects of its decline during perimenopause

· The importance of testing early and getting baseline hormone levels before symptoms appear

· How the DUTCH Test provides a picture of hormone metabolism, leading to clarity around estrogen metabolites, the HPA axis, and more

· Treating the hormonal root cause rather than prescribing medications for each symptom

Show Notes

Learn more about Dr. Asare Christian and his practice, Aether Medicine. Follow him on Instagram @aether_medicine!

Become a DUTCH Provider to get access to free educational resources, expert clinical support, comprehensive patient reports, and peer-reviewed and validated research.

A Practitioner’s Guide to Stress Patterns, Cortisol & Recovery Apr 28, 2026

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In this episode, Dr. Jaclyn Smeaton and Dr. Donielle Wilson discuss Dr. Donielle’s clinical philosophy, research findings, and personal journey around understanding and treating stress.

Their discussion also covers:

The stress response and how it’s highly individualized, shaped by genetics, and impacted by prior stress exposure
How standard cortisol testing misses most of the cortisol picture
Chronic stress and its cascade to multiple body systems, including the reproductive system in women
The five clinical stress patterns practitioners should be aware of
Small, consistent actions toward stress recovery, like mindfulness and deep breathing, can make a big difference

Show Notes

Learn more about Dr. Donielle Wilson and follow her on Instagram @drdoniwilson!

Check out the study mentioned in this episode, and learn more about Dr. Wilson’s book, Master Your Stress, Reset Your Health and her podcast, How Humans Heal.

Become a DUTCH Provider today to see how the DUTCH Test can profoundly change the lives of your patients.

Hormones, Sleep & Brain Health: Understanding Alzheimer’s Prevention Apr 21, 2026

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In this insightful episode, Dr. Heather Sandison and Dr. Jaclyn Smeaton discuss the root causes of cognitive decline and Alzheimer's, how a naturopathic approach differs from conventional medicine, and practical strategies for brain health at any age.

This episode also highlights:

The six drivers of cognitive decline
The impact of hormones, especially the steep drop in estrogen at menopause
How infections like Lyme disease, shingles, and COVID-19 can be linked to cognitive decline
Tips for early intervention, including the importance of sleep hygiene along with diet, exercise, and stress management
Using genetics to inform and optimize early intervention strategies

Show Notes

Learn more about Dr. Sandison and follow her on Instagram @dr.heathersandison!

Read the ovarian aging study mentioned by Dr. Smeaton in this episode.

Become a DUTCH Provider today to see how the DUTCH Test can profoundly change the lives of your patients.

What Triggers Acne? Optimizing Hormones & Gut Health Apr 14, 2026

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In this episode, Dr. Jaclyn Smeaton sits down with Dr. Bryant Esquejo, ND to unpack acne through a functional medicine lens, moving far beyond the surface to explore what’s really happening inside the body.

Dr. Esquejo and Dr. Smeaton also discuss:

Acne as not just a skin condition, but a reflection of imbalances involving hormones, blood sugar, inflammation, and the gut microbiome
The science behind acne development, from bacterial activity and oil production to deeper drivers like insulin resistance, androgen metabolism, and chronic inflammation
The influence of diet, stress, sleep, and gut health
How advanced testing, like hormone metabolite analysis, can reveal hidden imbalances in the body
Treating acne as an opportunity to better understand and optimize whole-body health

Learn more about Dr. Esquejo and follow him on Instagram @dr.bryant!

Check out Dr. Esquejo’s blog post on blood sugar, insulin, and acne, and read our whitepaper on 5a-Androstanediol as a marker of androgen status in women.

Become a DUTCH Provider to get access to free educational resources, expert clinical support, comprehensive patient reports, and peer-reviewed and validated research.

Test Before You Prescribe: A Low Testosterone Case Study Review Apr 07, 2026

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In this episode, Dr. Jaclyn Smeaton and DUTCH Founder Mark Newman discuss a case study published in Integrative Medicine: A Clinician’s Journal in which Mark himself was the patient. The case covers the step-by-step hormonal and metabolic effects of using HCG to boost endogenous testosterone, revealing how increasing testosterone can cascade into elevated estrogen, impaired estrogen clearance, and strained methylation capacity.

Their conversation also highlights:

The benefits of combining serum testing and DUTCH testing to monitor dosing as well as metabolism, clearance, and methylation
How methylation is affected by raising testosterone
The value of tracking step-by-step supplementation plans with repeated testing
The importance of baseline testing before beginning testosterone therapy
An upcoming research publication that compares hormone testing methods for testosterone monitoring

Read the DUTCH article and access the full IMCJ case report.

Become a DUTCH Provider to see how the DUTCH Test can profoundly change the lives of your patients.

What the DUTCH Test Reveals About Stress, Inflammation & Immune Health Mar 31, 2026

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Join Dr. Allison Smith and Dr. Jaclyn Smeaton for this episode as they share expert insights into how hormones, the HPA axis, and lifestyle factors influence immune health, injury risk, sleep, and overall well-being during perimenopause and menopause.

Dr. Smeaton and Dr. Smith also discuss:

The relationship between hormonal changes, stress, and inflammation
How cortisol and estrogen can impact sleep quality and inflammation in perimenopausal women
Patterns seen on DUTCH tests indicating inflammation, immune overactivation, or hormone resistance
Inflammation markers like quinolinate and melatonin and how they can help assess immune health
How hormonal fluctuations alter immune responses, leading to symptoms like itchy ears, joint pain, and autoimmunity

Show Notes

Check out our DUTCH Education Hub for more resources on perimenopause, menopause, stress, and inflammation!

Become a DUTCH Provider today to learn how the DUTCH Test can profoundly change the lives of your patients.

Menopausal Hair Loss & Innovations in Hair Restoration Mar 24, 2026

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In this episode, Dr. Alan Bauman and Dr. Jaclyn Smeaton discuss the complexities of hair restoration, particularly focusing on menopausal hair loss in women.

This discussion also explores:

Understanding female pattern hair loss
Emotional and hormonal factors affecting hair health
Innovative therapies that can aid in hair restoration, including stem cell therapy
The importance of nutrition and stress management in hair health
How personalized treatment plans can help effectively address hair loss in women

Show Notes:

Learn more about Dr. Bauman and follow him on Instagram @dralanbauman!

Become a DUTCH Provider to gain access to comprehensive patient reports, peer-reviewed and validated research, and expert clinical support.

How Holistic Health Transforms Fitness For Women Mar 17, 2026

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In this episode, Dr. Jaclyn and Jenn Pike explore the complexities of women's health, particularly in relation to exercise, nutrition, and hormonal balance. Jenn also shares her journey from working with professional athletes to focusing on everyday women.

This episode also highlights:

The evolution of women's fitness goals
How stress and inflammation affect overall well-being
The role of recovery, nutrition, and self-care
The pressures modern women face and how a supportive environment can help
How hormone health plays a role in fitness and in understanding the root cause of health concerns

Show Notes:

Learn more about Jenn Pike and follow her on Instagram @jennpike!

Become a DUTCH Provider to gain access to free educational resources, comprehensive patient reports, peer-reviewed and validated research, and expert clinical support.

Thriving in Perimenopause: How to Navigate Hormonal Shifts & Weight Gain Mar 10, 2026

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In this insightful episode, Dr. Mariza Snyder and Dr. Jaclyn Smeaton delve into the often-overlooked topic of perimenopause, shedding light on its complexities and the challenges women face during this transitional phase.

This episode also explores:

The role of estrogen in insulin sensitivity and how fluctuations can lead to weight gain, cravings, and muscle loss
Recognizing the signs of perimenopause, which can often be subtle and easily dismissed
The need for better education and support for both women and clinicians regarding perimenopause
The significance of DUTCH testing in providing a clearer picture of hormonal health
Empowering women to advocate for their health and seek support during perimenopause

Show Notes:

Check out Dr. Mariza’s book, The Perimenopause Revolution, and her podcast, Energized with Dr. Mariza! Follow Dr. Mariza on Instagram @drmariza.

Become a DUTCH Provider today to get access to free educational resources like our Perimenopause Management course, expert clinical support, peer-reviewed and validated research, and comprehensive patient reports.

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