Physionic

Latest Episodes:

United States Medicine in the 1800s; Zoonotic Origin of Viruses Jun 10, 2020

Show notes

Hey everyone, in this episode, I'll be going into a bit of history on how the United States handled their medical practices in the 1800s by comparison to Europe. I talk about the impact Johns Hopkins University had on the entire medical field in the United States, and then I discuss a bit on zoonotic viruses (viruses that jump from animals to humans).
Medical History: 1:36
Zoonotic Virus: 23:04
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Spices on Food that fight Cardiovascular Disease & Inflammation; Pain Perception in the Brain Jun 03, 2020

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In this episode, we'll be going into a bit of research on pain perception mediated by a particular area of the brain that wasn't pegged as one related to pain. Beyond that, do spices on food reduce inflammation and cardiovascular disease? If so, which ones?
Pain (2:01): Thuy Hua, Bin Chen, Dongye Lu, Katsuyasu Sakurai, Shengli Zhao, Bao-Xia Han, Jiwoo Kim, Luping Yin, Yong Chen, Jinghao Lu, Fan Wang. General anesthetics activate a potent central pain-suppression circuit in the amygdala. Nature Neuroscience, 2020; DOI: 10.1038/s41593-020-0632-8
Spices (10:17): Connie J Rogers, Penny M Kris-Etherton, Kristina S Petersen, Ester S Oh. Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial. The Journal of Nutrition, 2020; DOI: 10.1093/jn/nxaa063

How much does being Overweight INCREASE Risk of Severe CoVID-19 symptoms? Why are Fit people Dying? May 20, 2020

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In this episode, I go into two reviews discussing some of the data surrounding being overweight or obese and how much it increases risk of serious issues when dealing with CoVID-19. Also, why are fit people struggling with this infection, and what are some of the presented reasons/mechanisms?
Review 1: https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22842
Review 2: https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047659
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Understanding Microbes and How Fungi impact Us, ft. Alex Soare May 13, 2020

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In this episode, I had the absolute pleasure of having yet another smart scientist on the podcast. Alex Soare is on to discuss a bit of basic immunology and microbiology for the first half of the podcast, then we dive into fungi and her expertise on mucormycosis. I hope this proves as informative as I found it (considering I knew nothing about fungi).
Alex's Twitter: https://twitter.com/AlexandraYSoare
National AWIS Link: https://www.awis.org/
Baltimore AWIS: https://twitter.com/AWISBalt
https://www.instagram.com/awisbaltimore/
https://www.facebook.com/AWISBaltimore/
http://www.awisbaltimore.org/home
Time Stamps:
2:41 - Alex Education
4:34 - What is a microbe?
7:13 - Is a microbe a pathogen?
9:05 - Pathogen in a Host always causing disease?
15:53 - How do we fight disease? 21:53 - What is a fungus?
27:09 - Increase in fungal infections in the news - why?
31:57 - Do fungi mutate? 32:59 - What is Mucormycosis?
37:45 - How does it affect the body?
40:45 - Cures for Mucormycosis?
43:25 - Fungal infections are rare although they’re everywhere, why?
46:11 - Where is fungal research headed?
48:50- Is there an area in fungal research you’re excited?
50:32 - AWIS background
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How do Muscles convert Mechanical Force to Molecular signals? Well, its Confusing. May 07, 2020

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In this episode, I'll (attempt) walk us through two papers that have tried to answer how our muscles convert mechanical force/stimulus into a molecular signal that produce change. It's definitely not concrete and you will have to bear with me, but we're slowly getting to an answer.
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Hydroxychloroquine & Remdesivir work against CoVID-19? How? Apr 29, 2020

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In this episode, we dive into the big two drug players on the front against CoVID-19 - hydroxycloroquine and remdesivir. Do they work? If so, how do they work?
References:
Remdesivir:
https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins
https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056
Hydroxycloroquine:
https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v3
https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2
https://www.nature.com/articles/s41584-020-0372-x
https://www.nature.com/articles/s41421-020-0156-0

How CoVID-19 affects our Organs (other than the Lungs); Why your Mask is Ineffective and how to Fix it. Apr 22, 2020

Show notes

In this episode, I dive into a bit of less covered information related to coronavirus CoVID-19 related to the variety of organ systems it affects and how it might be exerting it's effect. I also give some quick information on how to effectively improve your mask that you produce for yourself.
Reference:
https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes?fbclid=IwAR1ZjxcdJiFXwSI_FfxhdBscZdT6G6jLc_RPEsnEL99CDe09_r8WE_p9VJc#
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420971/?fbclid=IwAR3Z4zChhXgvZPXk8M0We92wrneMF9h-tSnG8hxJ4fPOj_nCMaYwnXkd09c#__ffn_sectitle

Transhumanism: Uploading our Consciousness for the Future, ft. Neuroscientist Garrett Bunce Apr 15, 2020

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Hi everyone, this is a really special episode, because I had the absolute pleasure of having a super smart friend of mine come on the podcast to discuss a topic he's quite passionate about and on which knows a wealth of information. In this podcast, I discuss the topic of "Transhumanism" with Garrett Bunce. Transhumanism is moored in the idea of traveling consciousness beyond our current existence - can we "upload" our consciousness to a machine and continue our existence? If so, what hurdles are in the way and where are we in the process so far? Garrett takes it away - I hope you enjoy!
Garrett's Contact Information:
IG: @garryScary
Twitter: @garryscary
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Coronavirus Q&A; Bad Study on Effectiveness of Masks Apr 08, 2020

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In this episode, we'll be continuing our discussion of CoVID-19 coronavirus, as well as jumping into a bit of data in a study discussing the effectiveness of masks.
Study: https://www.nature.com/articles/s41591-020-0843-2/figures/1
Video:
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Responding to the Coronavirus Conspiracy Theorists Mar 25, 2020

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In this episode, I spend the entire time discussing the multitude of comments I have (and will) receive on my latest coronavirus video - hopefully you get some information out of it, at least.
Coronavirus Video: https://www.youtube.com/watch?v=j1lcAINElzY
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