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    Alternative Health

    Mastering Nutrition

    Welcome to the Mastering Nutrition podcast.

    Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person’s metabolism by finding their own unique unlocks.

    He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign’s College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.

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    Copyright: © All contents copyright of Chris Masterjohn.

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    Latest Episodes:
    Is it OK to take two milligrams a day of MK-4? | Masterjohn Q&A Files #215 Mar 09, 2021
    Show notes

    Question: Is it OK to take two milligrams a day of MK-4?Two milligrams, I don't have major safety concerns over, but I would prefer for most people who aren't dealing with a clinical soft-tissue calcification issue take more like 200 micrograms. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    How to feel great on a poor night's sleep? | Masterjohn Q&A Files #214 Mar 08, 2021
    Show notes

    Question: How to feel great on a poor night's sleep?I would say get rid of the poor night's sleep. And so that's go through the checklist of two to four hours of blue light blocking before bed, up to two to four hour, depending on your needs, psychological winding down routine, in which you clear everything off your to-do list, everything off your problem-solving list, focus on a paperback fiction, TV, video games, movies, et cetera. Deal with all those things first, because I don't think there is any magical one-off cure for poor night's sleep. And then if cold exposure helps, then that tells me that boosting norepinephrine is what's helping. So how do you boost norepinephrine? There's a lot of micronutrients involved in norepinephrine synthesis. So vitamin C, copper, salt, lots of things come into play, antioxidants that is. Cold exposure, maca root, coffee are probably the biggest things that you could use. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    What supplements should be taken by someone on PPIs? | Masterjohn Q&A Files #213 Mar 05, 2021
    Show notes

    Question: What supplements should be taken by someone on PPIs?I would first consider what you should do to get off the PPI. And so PPIs Are targeting stomach acid. And so I would first and foremost be thinking of excess histamine might be leading to excess stomach acid. You should probably try to eat a higher-protein diet, unless you're getting negative consequences from poor protein digestion. But if you're poorly digesting your protein, you are going to need more protein to nourish yourself. So I would think a higher protein diet and a multivitamin would really be the best things because there's too many nutrients whose absorption is going to be compromised by that. And then I don't really consider myself a gut specialist, but I would read up on what other people who are specializing in the gut are saying about how to compensate for PPI's with the microbiome, because I would think that would also come into play. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    Could methylglyoxal be causing elevated fasting glucose in low-carbers? | Masterjohn Q&A Files #212 Mar 04, 2021
    Show notes

    Question: Could methylglyoxal be causing elevated fasting glucose in low-carbers?Yes. I did my doctoral dissertation on methylglyoxal so I've covered it in a lot of different contexts, and the basic story is we know that diabetics have high methylglyoxal levels. We know that diabetics have high methylglyoxal-derived advanced glycation endproducts. And we know that this is true even when they're treated. Now that raises the question, does diabetes cause methylglyoxal to increase, or does methylglyoxal cause diabetes? And the answer is both. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    Is it important to hit the AI for total omega-6? | Masterjohn Q&A Files #211 Mar 03, 2021
    Show notes

    Question: Is it important to hit the AI for total omega-6?I think it's totally normal to not meet the AI for Omega-6 and to exceed the AI for Omega-3. Question is really, if you have systemic inflammation going on, you frame this as, should I strive to at least meet the AI for Omega-6 if I have chronic disease/inflammation? Well, if you have chronic disease/inflammation, you might be depleting your Omega-6, which means depleting arachidonic acid, which means you might need more arachidonic acid. If your arachidonic acid levels look good, you shouldn't worry at all about meeting the AI for linoleate as far as I'm concerned. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    How 30 minutes on the elliptical helps my head and neck tension | Masterjohn Q&A Files #210 Mar 02, 2021
    Show notes

    Question: How 30 minutes on the elliptical helps my head and neck tensionSo what the elliptical does is, it doesn't do a whole lot for moving my neck one way or another, but it does a lot for moving my thoracic spine and my shoulders through a pretty defined range of motion, not full range of motion going like this is, but it's a lot of movement through a considerable amount of that range of motion, and I think it's sufficient to give my thoracic spine and my shoulders a lot of circulation of fluid that nourishes the joints and keeps things moving.My experience with this is that 30 minutes on an elliptical three to five days a week, cause improvement. Five days or more cause very marked improvement, three days a week is more like maintenance, and below three days a week... If I had to simplify it, five days a week, 30 minutes a day on the elliptical causes improvement that just gets better week, after week, after week. Three days of 30 minutes on the elliptical per week will maintain whatever improvement I've gotten from doing five days a week, and less than three days a week will cause a regression. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    Why does it take time to be fat-adapted when our body already knows how to burn fat? | Masterjohn Q&A Files #209 Mar 01, 2021
    Show notes

    Question: Why does it take time to be fat-adapted when our body already knows how to burn fat?So the body does need time to get fat-adapted because yeah, the body knows how to burn fat, but fat adaptation is not about the body knowing how to burn fat, it's about the body increasing the expression of enzymes involved in burning fat. So everything that you do in the body requires enzymes. Enzymes are proteins that need to be made. It's going to increase enzymes involved in fat digestion and metabolism if you've been eating fat, and because it's expensive to do that, it's going to cut back on them if you haven't been eating fat. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    What should someone with FH eat if they also have prediabetes? | Masterjohn Q&A Files #208 Feb 26, 2021
    Show notes

    Question: What should someone with FH eat if they also have prediabetes?So first of all, it's a separable component of the diet so you need a low-saturated fat, low-cholesterol diet without necessarily eating a low-fat diet. Then second of all, the effect of that on blood lipids is dependent on the healthfulness of your insulin pathway. And so over time, that's something where you can play the balance between those two things and as you improve your blood glucose handling, you can fit in more carbohydrates to have a fuller dietary effect. For managing blood glucose, and I don't think it's a good idea to condemn all carbohydrates as a means of managing that. I think the best thing would be to get a continuous glucose monitor or a regular glucose monitor. If you're using a regular glucose monitor, use 30 minute, one hour, two hour, three hour, four hour time intervals after a meal and collect a baseline before a meal and look at how do different starches that you don't have an immunological response to... so you don't have to test grains because you don't tolerate them, but other foods that are rich in starches, whether it's carrots, or potatoes, or sweet potatoes, or whatever it is. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    How should I take zinc if it makes me nauseous? | Masterjohn Q&A Files #207 Feb 25, 2021
    Show notes

    Question: How should I take zinc if it makes me nauseous?As far as I know, there's no relationship between the nausea and zinc deficiency. I could be wrong, maybe there's research on it I haven't seen or it could be not researched but I don't think there's a connection. My guess would be that that is either related to her ionizing it faster in the GI tract than you, or something else related to her nausea impulse that might be nutritional, it might be genetic, it might be male/female. You could test out whether a little bit of bone broth or orange juice, or what have you with it buffers that enough to stop the nausea, and if it doesn't, I would just try to take it with a phytate-free meal. And by a phytate-free meal, I mean, a meal that doesn't have any whole grains, nuts, seeds, or legumes. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


    Can familial hypercholesterolemia be managed without statins? | Masterjohn Q&A Files #206 Feb 24, 2021
    Show notes

    Question: Can familial hypercholesterolemia be managed without statins?

    I think there's the general perspective that there's no point in having LDL-C be any higher than 50; therefore, since it doesn't matter, let's provide a sufficient margin of error where we're real confident that getting it down to 100 is great and so why not get it down to 50? If there is any extra protection we get it and we don't lose it.

    So my point of view would be, I would personally rather use a more conservative target of lowering down to 100 or so where the confidence is actually really high, because I'm not convinced by the lack of confidence that there's no neurological downside to pushing it twice as low as that. So that's my general perspective and if this were me, and it'll never be because I can't for the life of me get my total cholesterol above 160, but if it were me I'd be lowering my dose on that out of precaution on the other side.

    If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

    Access the show notes, transcript, and comments here.

    Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


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