Longevity Optimization with Kayla Barnes-Lentz

Twitter:https://x.com/femalelongevity

Website:https://www.kaylabarnes.com/

Spotify:https://open.spotify.com/show/4OLWWn22...

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Learn more about Dr Chris Masterjohn’s work:

Website: https://www.chrismasterjohn-phd.com/Instagram: https://www.instagram.com/chrismasterjohn/YouTube: https://www.youtube.com/@chrismasterjohn

Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy and Bone Health Jan 29, 2026

Show notes

In this episode, Dr. Jessica Shepard, board-certified OB/GYN and Chief Medical Officer of Hers, shares that the FDA just removed the black box warning on hormone replacement therapy after 23 years.

We discuss what actually happened with the WHI study that created all the fear around estrogen and breast cancer, and why the research never actually supported that narrative.
Dr. Shepard explains why you shouldn't wait until menopause to start the HRT conversation and how starting in your perimenopausal years can make all the difference for long-term health. Dr. Shepard shares the essential labs she runs on patients including ApoB, HbA1c, and thyroid optimization, plus the longevity metrics women should be tracking.
We also get into supplement recommendations including why she recommends 10 grams of creatine daily, the role of inflammation in aging, and how estrogen is naturally anti-inflammatory which is why women see increased cardiovascular risk and metabolic dysfunction after menopause.

Kayla's social + website:

Instagram: kaylabarnes

TikTok: femalelongevity

https://kayla-barnes-lentz.circle.so/...

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Dr. Jessica Shepherd's social + website:

Website: https://www.jessicashepherdmd.com/

Instagram: https://www.instagram.com/jessicashepherdmd/

Transform Your Health: https://eudemonia.net/?utm_source=podcast&utm_medium=kayla-podcast&utm_campaign=jessica-shepherd

Dr. Khanh Nguyen - The Blood Swap: Why Doctors Are Replacing Your Plasma With THIS Jan 22, 2026

Show notes

What if your blood is what’s making you sick and the key to reversing it is removing it?

In this episode, I sit down with Dr. Khanh Nguyen, a regenerative and anti-aging physician, to explore therapeutic plasma exchange and the rising use of young plasma. We talk detox, autoimmune disease, aging, peptides, and why your blood might be holding you back.

Kayla's social + website:

Instagram: kaylabarnes

TikTok: femalelongevity

Follow Her Female Protocol: https://www.protocol.kaylabarnes.comDr. Khanh's social + website:

Instagram: https://www.instagram.com/regenwithdrnguyen/

Website: Austin Regenerative Therapy

Dr. Ann Shippy, MD - The Fertility Alarm: Why 1 in 31 Kids Now Has Autism Jan 15, 2026

Show notes

Is your environment silently sabotaging your fertility?

Dr. Ann Shippy joins the show to reveal how hidden toxins, mold, and overlooked cellular damage may be accelerating ovarian aging and how to reclaim your fertility before it’s too late. From infertility misdiagnoses to rising autism rates, we dive deep into the tests most doctors never run, and the real impact your body’s toxic load has on future generations.

Kayla's social + website:

Instagram: kaylabarnes

TikTok: femalelongevity

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Dr. Ann Shippy social + website:

Instagram: https://www.instagram.com/annshippymd/
Website: https://annshippymd.com/

Ashley Koff, RD - Dietitian Reveals: The Hormone Problem That Makes You Eat Everything Jan 08, 2026

Show notes

Ashley Koff is a registered dietitian and author who spent 20 years discovering that weight and health aren't separate issues, they're connected through "weight health hormones." After her own struggles with restrictive eating despite doing everything "right," a functional medicine doctor helped her understand what was actually broken, and that was, her body's natural hormone function.

In this episode, Ashley explains why GLP-1 medications like Ozempic work, who actually needs them, and the critical foundational work required to avoid devastating rebounds. She reveals why current dietary guidelines fail women, shares her free weight health hormone assessment, cuts through the seed oil controversy, and offers practical strategies for eating healthy on any budget.

If you're confused about nutrition, frustrated that eating healthy isn't working, or curious about GLP-1 medications, this conversation provides the clarity you've been missing.

Guest’s socials + website:

Instagram: @ashleykoffapproved

Website: https://thebetternutritionprogram.com/

Kayla's social + website:

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Dr. Will Bulsiewicz, MD - The #1 Nutrient for Longevity That Everybody Still Ignores Jan 01, 2026

Show notes

In this video, Dr. Will Bulsiewicz shares his transformation from an overweight, depressed gastroenterologist to a gut health expert after meeting his now-wife changed his entire approach to food. He reveals why 95% of Americans are fiber deficient and how this single nutrient could be the key to longevity. Dr. B breaks down the science of the gut microbiome, explains why hyperpalatable foods force us to overeat 500 extra calories per day, and shares actionable strategies for rebuilding your gut health in as little as 3-5 days.

Guest’s socials + website

Instagram: @theguthealthmd

Website: https://theguthealthmd.com/

Kayla's social + website:

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

How to Make 2026 Your Healthiest Year Ever (Complete Guide) Jan 01, 2026

Show notes

Women don’t fail January — January fails women. Nearly 80% of New Year health goals are abandoned within weeks, not because of discipline, but because most plans ignore female biology. That’s why I created the 30-Day Female Longevity Challenge — a physiology-first way to prepare calmly and build health that actually lasts. Save $50 with code 2026. https://kayla-barnes-lentz.circle.so/checkout/female-longevity-challenge-2026?coupon_code=2026When you join, you also get one full year access to my female membership for on-going accountability, my monthly AMAs, a female support community, access to my 20 other courses and more! Optimizing your home: https://www.youtube.com/watch?v=Ni5GFTRWjikHome inspection: https://www.youtube.com/watch?v=8si4I1Bt5nMAt home health tracking: https://www.youtube.com/watch?v=23RUCOpBCE8&t=235s

Kayla's social + website:

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Dr. Sarah E. Hill, PhD - PMS Expert: Get Through Your Cycle Easier With These Simple Tricks Dec 18, 2025

Show notes

In this conversation, Kayla sits down with Dr. Sarah E. Hill, PhD to talk about the science behind PMS, cycle syncing, and why most health advice completely fails women. Dr. Hill explains the three main causes of PMS symptoms, natural hormonal shifts, one-size-fits-all protocols designed for men, and lack of cellular resilience.

Join the most comprehensive female-specific community for health and longevity optimization. After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.

https://kayla-barnes-lentz.circle.so/...

Follow Dr Sarah:

Instagram - https://g2ul0.app.link/KjuJon93HOb

Twitter - https://g2ul0.app.link/UFHinMb4HOb

Website - https://g2ul0.app.link/f3JSWDd4HOb

Kayla's social + website:

Instagram: / kaylabarnes

TikTok: / femalelongevity