VJOncology Podcast

Latest Episodes:

The multidisciplinary use of ctDNA in gastrointestinal cancers Feb 02, 2022

Show notes

Gastrointestinal (GI) cancer remains one of the leading cause of global cancer mortality. The current standard for diagnosing GI cancers via biopsy is costly and invasive, as well as lacking in reliability. As such, these methods are not used for screening and the majority of GI cancers are diagnosed in the advanced stages of cancer progression, when curative surgery is inadequate and patients must resort to other forms of treatment. When discovered and treated in the early stages, there is a much greater chance of curing GI cancers.

Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) are biomarkers that are released from the tumor into the plasma of patients. These liquid biopsies offer a non-invasive method for the screening and early diagnosis of GI cancers, holding the potential to improve survival rates for this patient population.

In this podcast, Scott Kopetz, MD, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, Naureen Starling, BSc, FRCP, MD, The Royal Marsden NHS Foundation Trust, London, UK and Justin Mencel, MBBS, The Royal Marsden NHS Foundation Trust, London, UK, discuss the use of ctDNA to screen for GI cancer, and the use of CTCs in determining minimal residual disease, including for the detection of microscopic amounts of disease following surgery.

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Breast Cancer Sessions: Highlights from SABCS 2021 with Lisa Carey & Aleix Prat Jan 14, 2022

Show notes

The San Antonio Breast Cancer Symposium 2021 featured exciting developments in early and advanced breast cancer, basic science, and translational research.

In this podcast, we had the opportunity to hear from Lisa A. Carey (UNC Lineberger, Chapel Hill, NC) and Aleix Prat (Hospital Clínic Barcelona, Barcelona, Spain) who discuss advances in breast cancer care and management, including highlights from the meeting, as well as recent updates from the MONALEESA studies.

The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.

The post Breast Cancer Sessions: Highlights from SABCS 2021 with Lisa Carey & Aleix Prat appeared first on VJOncology.

Immunotherapy updates from SABCS 2021 with Heather McArthur & Kevin Kalinsky Jan 04, 2022

Show notes

The success of immunotherapy in the treatment of solid tumors has created hope for its potential in breast cancer. The San Antonio Breast Cancer Symposium 2021 showcased an array of updates in breast cancer care and management, including updates on pivotal trials evaluating the use of immunotherapy in breast cancer.

In this podcast, we hear from leading experts, Kevin Kalinsky (Emory University, Atlanta, GA) and Heather McArthur (UT Southwestern Medical Center, Dallas, TX) who discuss the latest advances in immunotherapy for breast cancer presented at the hybrid SABCS 2021 meeting and what the latest research means for the clinic.

The Breast Cancer Podcasts on VJOncology are supported by Seagen. Seagen have no influence over the production of the content.

The post Immunotherapy updates from SABCS 2021 with Heather McArthur & Kevin Kalinsky appeared first on VJOncology.

The Lung Cancer Sessions: Advances in EGFR-mutated NSCLC Nov 25, 2021

Show notes

The Lung Cancer Sessions from VJOncology aim to provide interesting perspectives from leading experts on the big topics in lung cancer research. In this podcast, Ross Camidge, MD, PhD, of University of Colorado, Aurora, CO, chairs a lively discussion on the latest advances and standard clinical practices in EGFR-mutated NSCLC, including EGFR testing, options for first-line treatment, and developments in immunotherapy.

He is joined by Rosario Garcia Campelo, MD, of Coruña University Hospital, A Coruña, Spain, Natasha Leighl, MD, MMSc, FRCPC, of Princess Margaret Cancer Center, Toronto, Canada, and Alexander Spira, MD, PhD, FACP, of Virginia Cancer Specialists, Fairfax, VA.

The post The Lung Cancer Sessions: Advances in EGFR-mutated NSCLC appeared first on VJOncology.

ISLB 2021: Current standards and future directions for liquid biopsy Nov 12, 2021

Show notes

Liquid biopsy is an exciting field, with many promising advances in recent years. In this podcast, we cover a range of possible uses of liquid biopsy throughout all stages of patient care, from early diagnosis and screening to post-treatment monitoring. We also discuss some of the key challenges that need to be overcome and think about the future of liquid biopsy research.

We are joined by four speakers from the International Society of Liquid Biopsy (ISLB) Virtual Meeting 2021, Professor David Gandara, from UC Davis Comprehensive Cancer Center in Sacramento, California, Professor Natasha Leighl, from the Princess Margaret Cancer Center in Toronto, Canada, Professor Heinz Josef Lenz, from the University of Southern California, in Los Angeles, California, and Professor Catherine Alix-Panabieres from the University Medical Center of Montpellier in France.

The post ISLB 2021: Current standards and future directions for liquid biopsy appeared first on VJOncology.

Prostate Cancer Highlights from ESMO 2021 with Robert Jones Oct 28, 2021

Show notes

The European Society for Medical Oncology (ESMO) 2021 Congress saw many exciting clinical trials presented from across the field of oncology, some of which are paving the way for new standards of care for patients. Among the biggest readouts for the field of prostate cancer were the STAMPEDE (NCT00268476), PEACE-1 (NCT01957436), and ARCHES (NCT02677896) studies. In this podcast, we are joined by Robert Jones, MD, PhD, from the University of Glasgow and Beatson West of Scotland Cancer Centre, Glasgow, UK, as he provides an overview of the biggest news in prostate cancer from ESMO 2021.

The post Prostate Cancer Highlights from ESMO 2021 with Robert Jones appeared first on VJOncology.

The GU Cancer Sessions: Bladder Highlights from ESMO 2021 Oct 19, 2021

Show notes

VJOncology has assembled a group of leading genitourinary cancer experts to examine and discuss the latest developments in bladder cancer presented at the European Society for Medical Oncology (ESMO) 2021 Annual Meeting.

Listen to this insightful roundtable discussion featuring Laurence Albiges, Gustave Roussy Institute, Villejuif, France, and Enrique Grande, MD Anderson Cancer Center Madrid, Madrid, Spain, to hear about ground-breaking erdafitinib data from NORSE in metastatic or locally advanced urothelial carcinoma, as well as VESPER in muscle-invasive bladder cancer (MIBC). They additionally examine innovative data on pembrolizumab in combination with anti- Ephrin-B2 sEphB4-HSA in advanced urothelial carcinoma.

The post The GU Cancer Sessions: Bladder Highlights from ESMO 2021 appeared first on VJOncology.

The Skin Cancer Sessions: Highlights from ASCO 2021 Oct 07, 2021

Show notes

VJOncology has assembled a panel of world-renowned skin cancer experts to examine and discuss the exciting advances in skin cancer presented at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting.

In this exclusive podcast, James Larkin, MD, PhD, Royal Marsden Hospital, London, UK, is joined by Rodabe Amaria, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, Ana Arance, MD, PhD, Hospital Clínic de Barcelona, Barcelona, Spain, and Paolo Ascierto, MD, National Tumor Institute, Milan, Italy.

Listen to this insightful roundtable discussion to learn about the latest clinical trial data in skin cancer, including updates in adjuvant pembrolizumab in the KEYNOTE-054 and S1404 trials, as well as neoadjuvant ipilimumab plus nivolumab in OpACIN-neo trial. Additional topics of discussion include long-term follow-up in the CheckMate 067 and COLUMBUS trials, relatlimab plus nivolumab in RELATIVITY-047, lenvatinib in the anti-PD-1 refractory space in LEAP-004, and much more.

The post The Skin Cancer Sessions: Highlights from ASCO 2021 appeared first on VJOncology.

The Lung Cancer Sessions: Highlights from ASCO 2021 Oct 07, 2021

Show notes

Following the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting, VJOncology brought together a group of leading lung cancer experts to offer their perspectives on the latest research advances presented at the meeting and how they could impact lung cancer care in the future.

In this exclusive post-ASCO podcast, Melissa Johnson, MD, Sarah Cannon Research Institute, Nashville, TN, is joined by Lizza Hendriks, MD, PhD, Maastricht University, Maastricht, Netherlands, and Heather Wakelee, MD, Stanford University, Stanford, CA, as they delve into the latest practice-changing lung cancer data.

Listen to this esteemed panel discuss adjuvant trials including IMpower010, CTONG1103 and IMPACT, as well as biomarkers of response. The panel also cover targeted therapies including KRAS inhibitors such as sotorasib, HER3-directed antibody-drug-conjugates, as well as the treatment of lung cancer with EGFR exon 20 insertions.

The post The Lung Cancer Sessions: Highlights from ASCO 2021 appeared first on VJOncology.

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