This Week in Neuroscience

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**This Week in Neuroscience**

A podcast about the nervous system.

Latest Episodes:

TWiN 26: Immunological memory in the brain Jan 31, 2022

Show notes

TWiN reviews evidence in mice that brain neurons encode and retrieve specific immune responses.

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Memory of immunity (Cell)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 25: Thanks for listening Dec 28, 2021

Show notes

TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutrophils that promote neuron survival.

Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung

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Males and females in neuroscience studies (New Scientist)
Brain rotates memories (Quanta)
Odorant receptors in brain (one, two)
Neutrophils promote neuron survival (Nat Imm)
Letters read on TWiN 25
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 24: Social transmission of maternal behavior with Ioana Carcea and Robert Froemke Nov 24, 2021

Show notes

Ioana and Robert join TWiN to discuss their work demonstrating that rodents acquire maternal behavior by social transmission from an experienced mother to a virgin female how to care for a litter via endogenous oxytocin.

Hosts: Vincent Racaniello and Timothy Cheung

Guests: Ioana Carcea and Robert Froemke

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Oxytocin neurons and social transmission of behavior (Nature)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe

TWiN 23: Peripheral nervous system with Bruce Carter Oct 31, 2021

Show notes

Bruce Carter joins TWiN to discuss the peripheral nervous system: the development of nerves that convey sensory information like touch from the tips of your toes to the brain, and Schwann cells, which are necessary for ensuring that those sensory signals are sustained as they travel long distances to the brain.

Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison

Guest: Bruce Carter

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Control of neuron survival by p75 (J Neurosci)
Sympathetic nervous system (Nat Rev Neurosci)
Charcot-Marie-Tooth and PMP22 protein (J Biol Chem)
Satellite glial cells (Nat Rev Neurosci)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 22: It's never lupus Sep 29, 2021

Show notes

TWiN explains how anti-DNA antibodies present in lupus patients bind to GluN2A-containing NMDA receptors, act as positive allosteric modulators, and impair spatial memory.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Lupus autoantibodies bind GluN2A-containing NMDA receptors (Nat Commun)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 21: How do we know if a mouse is hallucinating? Aug 24, 2021

Show notes

TWiN explores a study of hallucination-like perception in mice which supports the idea that hallucinations arise as faulty perceptual inferences due to elevated dopamine in the striatum.

Hosts: Vincent Racaniello, Ori Lieberman, and Timothy Cheung

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Listener poll - please take it
Striatal dopamine and hallucination in mice (Science)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 20: Drifting aromas in the brain Jul 14, 2021

Show notes

While perceptual constancy requires the brain to maintain a stable representation of sensory input, TWiN explores a study showing that odor-evoked responses in the olfactory cortex drift over periods of days to weeks.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Representational drift in olfactory cortex (Nature) (open preprint)
Ed Yong on representational drift (Atlantic)
Letters read on TWiN 20
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 19: Glia 101 Jun 21, 2021

Show notes

On this episode, Vivianne gives a primer on glial cells, with the goal of thinking about the central nervous system holistically and appreciating the different cell types that contribute to its function.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Subscribe (free): iTunes, Google Podcasts, RSS, email

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Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 18: Autism and the gut microbiome with Mauro Costa-Mattioli May 12, 2021

Show notes

Mauro Costa-Mattioli joins TWiN to discuss how his laboratory dissects the contribution of host genetics and the microbiome in complex neurodevelopment disorders such as autism spectrum disorders.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Mauro Costa-Mattioli

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Mauro's work on TWiM 131 and 193
Separating genetics and microbiome in autism (Cell)
Please take our listener poll
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 17: Worms see the light with Michael Nitabach Apr 21, 2021

Show notes

Michael Nitabach joins TWiN to discuss the finding that the nematode C. elegans, which do not have eyes, can discriminate between colors to guide foraging decisions and move them away from harmful bacteria that produce a blue-pigment toxin.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Michael Nitabach

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