This Week in Neuroscience

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TWiN 5: Anosmia and COVID-19 Apr 18, 2020

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Bob Datta joins TWiN to reveal the findings of his laboratory on expression of SARS-CoV-2 entry genes in the olfactory epithelium and the implications for anosmia associated with COVID-19.

Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, Erin Calipari and Vincent Racaniello

Guest: Bob Datta

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Expression of SARS-CoV-2 entry genes in nasal olfactory epithelium (bioRxiv)
Expression of SARS-CoV-2 entry genes in nasal olfactory epithelium (bioRxiv)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 4: It's a trap! Jan 09, 2020

Show notes

Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons.

Hosts: Andres Bendesky, Jason Shepherd, and Vincent Racaniello

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Arc is a repurposed retrotransposon gag protein that mediates intercellular RNA transfer (Cell)
Drosophila gag-like ARC1 (Cell)
Letters read on TWiN #4
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 3: Gambling on dopamine Dec 18, 2019

Show notes

Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction.

Hosts: Ori Lieberman, Erin Calipari,Jason Shepherd, and Vincent Racaniello

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Dopamine neurons encode reward probability and uncertainty (Science)
Letters read on TWiN #3

Intro music is by Ronald Jenkees.

Send your neuroscience questions and comments to twin@microbe.tv

TWiN 2: Cells that fire together wire together Nov 05, 2019

Show notes

The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing.

Hosts: Ori Lieberman, Andres Bendesky,Jason Shepherd, and Vincent Racaniello

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Links for this episode