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The Immunology Podcast — Natural Sciences
The Immunology Podcast

A podcast featuring conversations with immunologists from around the globe. Brought to by STEMCELL Technologies.

Latest Episodes:

Ep. 78: “Artificial Intelligence and Immunology” Featuring Drs. Jo Viney and Ryan Peckner May 21, 2024
Show notes

Guests:

Dr. Jo Viney is the CEO, President, & Co-Founder and Dr. Ryan Peckner is the Director of Machine Learning & Computational Biology at Seismic Therapeutic. In this special episode recorded in front of a live audience at IMMUNOLOGY2024 in Chicago, they discuss artificial intelligence and its applications in drug discovery and protein engineering. They talk about its limitations, its role in clinical trials, and how scientists can leverage these tools to advance their careers.

Featured Products and Resources:

Catch up on daily summaries of IMMUNOLOGY2024 sessions.

Prepare for your next conference!

Images courtesy of Drs. Jo Viney and Ryan Peckner

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Ep. 78: “Artificial Intelligence and Immunology” Featuring Drs. Jo Viney and Ryan Peckner May 21, 2024
Show notes

Guests:

Dr. Jo Viney is the CEO, President, & Co-Founder and Dr. Ryan Peckner is the Director of Machine Learning & Computational Biology at Seismic Therapeutic. In this special episode recorded in front of a live audience at IMMUNOLOGY2024 in Chicago, they discuss artificial intelligence and its applications in drug discovery and protein engineering. They talk about its limitations, its role in clinical trials, and how scientists can leverage these tools to advance their careers.

Featured Products and Resources:

Catch up on daily summaries of IMMUNOLOGY2024 sessions.

Prepare for your next conference!

Images courtesy of Drs. Jo Viney and Ryan Peckner

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Never miss updates about new episodes.
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IMMUNOLOGY2024™: Day 5 May 08, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting, where Brenda and Jason talk about sessions including the dysfunction of exhaustive T cells enforced by MCT11-mediated lactate metabolism and extrafollicular differentiated B cells, presented by former podcast guest Dr. Frances Lund.

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IMMUNOLOGY2024™: Day 5 May 08, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting, where Brenda and Jason talk about sessions including the dysfunction of exhaustive T cells enforced by MCT11-mediated lactate metabolism and extrafollicular differentiated B cells, presented by former podcast guest Dr. Frances Lund.

Featured Products and Resources:

Prepare for your next conference

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Never miss updates about new episodes.
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IMMUNOLOGY2024™: Day 4 May 07, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting, where Brenda and Jason highlight discussions on tumor-infiltrating lymphocyte therapy, chaired by former podcast guest Dr. Kristin Anderson, as well as fueling T cell fate decision during infection with an initial focus on immunometabolism.

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Download a free ebook on cell separation!

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IMMUNOLOGY2024™: Day 4 May 07, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting, where Brenda and Jason highlight discussions on tumor-infiltrating lymphocyte therapy, chaired by former podcast guest Dr. Kristin Anderson, as well as fueling T cell fate decision during infection with an initial focus on immunometabolism.

Featured Products and Resources:

Download a free ebook on cell separation!

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

IMMUNOLOGY2024™: Day 3 May 06, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason spotlight discussions on cellular responses of microbial and parasitic infection and the immunology of pregnancy with a focus on glycan regulation of fetomaternal tolerance.

Featured Products and Resources:

Explore free immunology wallcharts!

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IMMUNOLOGY2024™: Day 3 May 06, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason spotlight discussions on cellular responses of microbial and parasitic infection and the immunology of pregnancy with a focus on glycan regulation of fetomaternal tolerance.

Featured Products and Resources:

Explore free immunology wallcharts!

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

IMMUNOLOGY2024™: Day 2 May 05, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions including microbial and environmental influences on the gut and recent breakthroughs in emerging therapeutic strategies for chronic inflammatory and fibrotic diseases.

Featured Products and Resources:

Stay up-to-date with the latest in immune regulation news.

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Never miss updates about new episodes.
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IMMUNOLOGY2024™: Day 2 May 05, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions including microbial and environmental influences on the gut and recent breakthroughs in emerging therapeutic strategies for chronic inflammatory and fibrotic diseases.

Featured Products and Resources:

Stay up-to-date with the latest in immune regulation news.

Subscribe to our newsletter!

Never miss updates about new episodes.
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IMMUNOLOGY2024™: Day 1 May 04, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda highlight sessions on innate and innate-like cells and transplant immunology. Discussions include the role of hypothermia in protecting ventilator-induced lung damage and Siglec-E knockout in transplant rejection.

Featured Products and Resources:

Stay up-to-date with the latest in human immunology news.

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Never miss updates about new episodes.
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IMMUNOLOGY2024™: Day 1 May 04, 2024
Show notes

In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda highlight sessions on innate and innate-like cells and transplant immunology. Discussions include the role of hypothermia in protecting ventilator-induced lung damage and Siglec-E knockout in transplant rejection.

Featured Products and Resources:

Stay up-to-date with the latest in human immunology news.

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

Caleb Lareau — Ep. 77: “Computational and Translational Immunology” Featuring Dr. Caleb Lareau Apr 23, 2024
Show notes

Guest:

Dr. Caleb Lareau is an Assistant Professor at Memorial Sloan Kettering Cancer Center. His lab aims to understand how cells in our bodies adapt, expand, and evolve during the course of our lives, particularly in the immune system. He talks about cross-training in bioinformatics and immunology, and herpesvirus reactivation in CAR T cells.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024, happening May 3-7 in Chicago!

Attend a live show on artificial intelligence in immunology.

The Immunology Round Up

Blocking Lung Injury in Influenza – Scientists developed an inhibitor to block necroptosis in severe influenza infections.

Germinal Center Memory B Cells – IL-4 signaling can regulate memory B cell selection.

Intestinal Barrier Defence – Citrobacter rodentium targets a subset of absorptive intestinal epithelial cells in the mid–distal colon, which stimulate T cells to produce sustained IL-22 signals to mitigate further spread of the pathogen.

Fast-Acting Glucocorticoids – The anti-inflammatory properties of glucocorticoids involve reprogramming of the mitochondrial metabolism of macrophages.

Image courtesy of Dr. Caleb Lareau

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Ep. 77: “Computational and Translational Immunology” Featuring Dr. Caleb Lareau Apr 23, 2024
Show notes

Guest:

Dr. Caleb Lareau is an Assistant Professor at Memorial Sloan Kettering Cancer Center. His lab aims to understand how cells in our bodies adapt, expand, and evolve during the course of our lives, particularly in the immune system. He talks about cross-training in bioinformatics and immunology, and herpesvirus reactivation in CAR T cells.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024, happening May 3-7 in Chicago!

Attend a live show on artificial intelligence in immunology.

The Immunology Round Up

Blocking Lung Injury in Influenza – Scientists developed an inhibitor to block necroptosis in severe influenza infections.

Germinal Center Memory B Cells – IL-4 signaling can regulate memory B cell selection.

Intestinal Barrier Defence – Citrobacter rodentium targets a subset of absorptive intestinal epithelial cells in the mid–distal colon, which stimulate T cells to produce sustained IL-22 signals to mitigate further spread of the pathogen.

Fast-Acting Glucocorticoids – The anti-inflammatory properties of glucocorticoids involve reprogramming of the mitochondrial metabolism of macrophages.

Image courtesy of Dr. Caleb Lareau

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Never miss updates about new episodes.
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Ep. 76: “Innate-Like T Lymphocytes” Featuring Dr. Mitchell Kronenberg Apr 09, 2024
Show notes

Guest:

Dr. Mitchell Kronenberg is a Professor and President Emeritus at La Jolla Institute for Immunology. His lab studies how innate-like T cells adapt to different tissue environments. He talks about his work on MAIT cells and mucosal immunology, as well as his time leading the Institute.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024, taking place May 3-7 in Chicago!

Get updates about new mentorship content from Lab Coats & Life.

The Immunology Science Round Up

Immune System Regeneration – Depleting myeloid-biased HSCs in aged mice restores features of a more youthful immune system.

Gasdermin in Pyroptosis – Gasdermin D N-terminal domain palmitoylation controls gasdermin membrane localization and activation.

Antibody-Drug Conjugates for Cancer – Scientists developed an antibody–drug conjugate that could kill TRBC1⁺ cancer cells in vitro and cure human T cell cancers in mouse models.

Hemorrhagic Fever Cell Receptors – The low density lipoprotein receptor is critical for the Crimean–Congo hemorrhagic fever virus to enter host cells.

Image courtesy of Dr. Mitchell Kronenberg

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Ep. 76: “Innate-Like T Lymphocytes” Featuring Dr. Mitchell Kronenberg Apr 09, 2024
Show notes

Guest:

Dr. Mitchell Kronenberg is a Professor and President Emeritus at La Jolla Institute for Immunology. His lab studies how innate-like T cells adapt to different tissue environments. He talks about his work on MAIT cells and mucosal immunology, as well as his time leading the Institute.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024, taking place May 3-7 in Chicago!

Get updates about new mentorship content from Lab Coats & Life.

The Immunology Science Round Up

Immune System Regeneration – Depleting myeloid-biased HSCs in aged mice restores features of a more youthful immune system.

Gasdermin in Pyroptosis – Gasdermin D N-terminal domain palmitoylation controls gasdermin membrane localization and activation.

Antibody-Drug Conjugates for Cancer – Scientists developed an antibody–drug conjugate that could kill TRBC1⁺ cancer cells in vitro and cure human T cell cancers in mouse models.

Hemorrhagic Fever Cell Receptors – The low density lipoprotein receptor is critical for the Crimean–Congo hemorrhagic fever virus to enter host cells.

Image courtesy of Dr. Mitchell Kronenberg

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

Ep. 75: “Autoinflammatory Diseases” Featuring Dr. Scott Canna Mar 26, 2024
Show notes

Guest:

Dr. Scott Canna is an Associate Professor of Pediatrics (Rheumatology), and Attending Physician, Pediatric Rheumatology and Immune Dysregulation at the Children’s Hospital of Philadelphia. His group studies the mechanisms of immune dysregulation. He talks about auto- and hyperinflammatory diseases and the role of IL-18. He also discusses hemophagocytic lymphohistiocytosis and adapting therapies for children.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024!

Listen to the new Lab Coats & Life Podcast, featuring Brenda and Jason as co-hosts!

The Immunology Science Round Up

Microbial Metabolites in Infectious Diseases – Dietary tryptophan protects against gastrointestinal infection by activating the neurotransmitter receptor dopamine receptor D2.

T Cell Tolerance – Scientists used neural networks and hybrid mice to see how the transcription factor AIRE recognizes gene promoters.

Microbes in Immunotherapy – Lactobacillus johnsonii promotes the production of indole-3-propionic acid, which improves immune checkpoint blockade responsiveness.

Alzheimer’s Disease Microglia – Research suggests a link between genetic risk factors for Alzheimer’s disease and microglial lipid droplet accumulation.

Image courtesy of Dr. Scott Canna

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Ep. 75: “Autoinflammatory Diseases” Featuring Dr. Scott Canna Mar 26, 2024
Show notes

Guest:

Dr. Scott Canna is an Associate Professor of Pediatrics (Rheumatology), and Attending Physician, Pediatric Rheumatology and Immune Dysregulation at the Children’s Hospital of Philadelphia. His group studies the mechanisms of immune dysregulation. He talks about auto- and hyperinflammatory diseases and the role of IL-18. He also discusses hemophagocytic lymphohistiocytosis and adapting therapies for children.

Featured Products and Resources:

Check out the program for IMMUNOLOGY2024!

Listen to the new Lab Coats & Life Podcast, featuring Brenda and Jason as co-hosts!

The Immunology Science Round Up

Microbial Metabolites in Infectious Diseases – Dietary tryptophan protects against gastrointestinal infection by activating the neurotransmitter receptor dopamine receptor D2.

T Cell Tolerance – Scientists used neural networks and hybrid mice to see how the transcription factor AIRE recognizes gene promoters.

Microbes in Immunotherapy – Lactobacillus johnsonii promotes the production of indole-3-propionic acid, which improves immune checkpoint blockade responsiveness.

Alzheimer’s Disease Microglia – Research suggests a link between genetic risk factors for Alzheimer’s disease and microglial lipid droplet accumulation.

Image courtesy of Dr. Scott Canna

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

Ep. 74: “Dengue Pathogenesis” Featuring Dr. Neelika Malavige Mar 12, 2024
Show notes

Guest:

Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and biomarkers. She talks about the disease burden of dengue and her investigations into risk factors for severe disease. She also discusses her research on COVID-19 vaccines and the role of the microbiome in colon cancer, as well as how she’s working to grow research capabilities in Sri Lanka.

Featured Products and Resources:

Register now for IMMUNOLOGY2024, happening May 3 – 7 in Chicago!

Enter to win a free lab coat from the new Lab Coats & Life Podcast.

The Immunology Round Up

SOX17 in Colorectal Cancer – Scientists used AKP organoids to demonstrate that SOX17 orchestrates immune evasion in the early steps of colon cancer.

Tregs in Tumor Immunity – Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade.

Astrocytes in Autoimmunity – Researchers identified astrocyte-derived heparin-binding EGF-like growth factor as a potential therapeutic target in multiple sclerosis.

αβ T Cell Development – By studying patients with pre-TCRα deficiency, scientists found that pre-TCRα may not be absolutely required for αβ T cell development in humans.

Image courtesy of Dr. Neelika Malavige

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Never miss updates about new episodes.
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Ep. 74: “Dengue Pathogenesis” Featuring Dr. Neelika Malavige Mar 12, 2024
Show notes

Guest:

Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and biomarkers. She talks about the disease burden of dengue and her investigations into risk factors for severe disease. She also discusses her research on COVID-19 vaccines and the role of the microbiome in colon cancer, as well as how she’s working to grow research capabilities in Sri Lanka.

Featured Products and Resources:

Register now for IMMUNOLOGY2024, happening May 3 – 7 in Chicago!

Enter to win a free lab coat from the new Lab Coats & Life Podcast.

The Immunology Round Up

SOX17 in Colorectal Cancer – Scientists used AKP organoids to demonstrate that SOX17 orchestrates immune evasion in the early steps of colon cancer.

Tregs in Tumor Immunity – Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade.

Astrocytes in Autoimmunity – Researchers identified astrocyte-derived heparin-binding EGF-like growth factor as a potential therapeutic target in multiple sclerosis.

αβ T Cell Development – By studying patients with pre-TCRα deficiency, scientists found that pre-TCRα may not be absolutely required for αβ T cell development in humans.

Image courtesy of Dr. Neelika Malavige

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Never miss updates about new episodes.
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