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The Immunology Podcast — Natural Sciences
The Immunology Podcast

A podcast featuring conversations with immunologists from around the globe. Brought to by STEMCELL Technologies.

Latest Episodes:

IMMUNOLOGY2025™: Day 4 May 07, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, where we recorded daily episodes highlighting key developments from the previous 24 hours. This is the fourth of five special episodes from the meeting. In this episode, Brenda and Jason discuss how macrophages contribute to lung tissue repair and influence hormone activity, as well as the mechanisms linking MHC-II abnormalities to autoimmune disease pathogenesis.

Featured Products and Resources:

Register: On-Demand Human Immune Cell Isolation Course

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IMMUNOLOGY2025™: Day 4 May 07, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, where we recorded daily episodes highlighting key developments from the previous 24 hours. This is the fourth of five special episodes from the meeting. In this episode, Brenda and Jason discuss how macrophages contribute to lung tissue repair and influence hormone activity, as well as the mechanisms linking MHC-II abnormalities to autoimmune disease pathogenesis.

Featured Products and Resources:

Register: On-Demand Human Immune Cell Isolation Course

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

IMMUNOLOGY2025™: Day 3 May 06, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions on mucosal immunology and the role of T cells in lactogenesis. They also talk about γδ CAR T cells and veterinary immunology — from sharks to elephants.

Featured Products and Resources:

Free mouse immune cell wallchart

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IMMUNOLOGY2025™: Day 3 May 06, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions on mucosal immunology and the role of T cells in lactogenesis. They also talk about γδ CAR T cells and veterinary immunology — from sharks to elephants.

Featured Products and Resources:

Free mouse immune cell wallchart

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Never miss updates about new episodes.
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IMMUNOLOGY2025™: Day 2 May 05, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions on tumor-infiltrating lymphocyte and T-cell receptor therapies, unconventional functions of Tregs, and advances in single-cell RNA sequencing.

Featured Products and Resources:

Register: On-Demand Human T Cell Expansion Course

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Never miss updates about new episodes.
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IMMUNOLOGY2025™: Day 2 May 05, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions on tumor-infiltrating lymphocyte and T-cell receptor therapies, unconventional functions of Tregs, and advances in single-cell RNA sequencing.

Featured Products and Resources:

Register: On-Demand Human T Cell Expansion Course

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

IMMUNOLOGY2025™: Day 1 May 04, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting. Brenda and Jason discuss highlights from talks including immune responses to bacterial infections, p53 reactivation for cancer therapy, and the mechanisms that lead to celiac disease.

Featured Products and Resources:

Stay up-to-date with the latest in immune regulation news.

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IMMUNOLOGY2025™: Day 1 May 04, 2025
Show notes

In May 2025, we attended IMMUNOLOGY2025, the annual meeting of the American Association of Immunologists in Honolulu, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting. Brenda and Jason discuss highlights from talks including immune responses to bacterial infections, p53 reactivation for cancer therapy, and the mechanisms that lead to celiac disease.

Featured Products and Resources:

Stay up-to-date with the latest in immune regulation news.

Subscribe to our newsletter!

Never miss updates about new episodes.
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Ep. 103: “Immunophysiology” Featuring Dr. Henrique Veiga-Fernandes Apr 22, 2025
Show notes

Guest:

Dr. Henrique Veiga-Fernandes is a Full Investigator and Group Leader at the Champalimaud Foundation. He talks about interactions between the nervous and immune systems and how ILC2s regulate blood glucose levels. (43:00)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Acetylcholine Receptor in Autoimmunity – Researchers used cryoelectron microscopy to determine the high-resolution structures of the human adult AChR in different functional states. (5:20)

Skin Damage and Immune Responses – Acute and chronic inflammation in the skin of mice can initiate humoral immune responses to bystander antigens in the gut. (12:35)

Gut Microbes and Th17 Cells – A. faecalis outer membrane vesicles promote intestinal Th17 cell generation. (23:15)

Sex Differences in Pain Sensing – Depleting Tregs cells localized to the meninges of the central nervous system increased the responses of female, but not male, mice to mechanical pain stimuli. (32:00)

Image courtesy of Dr. Henrique Veiga-Fernandes

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Ep. 103: “Immunophysiology” Featuring Dr. Henrique Veiga-Fernandes Apr 22, 2025
Show notes

Guest:

Dr. Henrique Veiga-Fernandes is a Full Investigator and Group Leader at the Champalimaud Foundation. He talks about interactions between the nervous and immune systems and how ILC2s regulate blood glucose levels. (43:00)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Acetylcholine Receptor in Autoimmunity – Researchers used cryoelectron microscopy to determine the high-resolution structures of the human adult AChR in different functional states. (5:20)

Skin Damage and Immune Responses – Acute and chronic inflammation in the skin of mice can initiate humoral immune responses to bystander antigens in the gut. (12:35)

Gut Microbes and Th17 Cells – A. faecalis outer membrane vesicles promote intestinal Th17 cell generation. (23:15)

Sex Differences in Pain Sensing – Depleting Tregs cells localized to the meninges of the central nervous system increased the responses of female, but not male, mice to mechanical pain stimuli. (32:00)

Image courtesy of Dr. Henrique Veiga-Fernandes

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Never miss updates about new episodes.
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Ep. 102: “RNA-Binding Proteins” Featuring Dr. Monika Wolkers Apr 08, 2025
Show notes

Guest:

Dr. Monika Wolkers is a Group Leader at the Sanquin Blood Supply Foundation and an Associate Professor at the University of Amsterdam. Her research focuses on RNA-binding proteins and how they affect T cell function. She talks about γδ T cells in immunotherapy, targeting pediatric tumors, and how a sabbatical led her to study RNA-binding proteins. (46:50)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Macrophages in Liver Regeneration – Glutamate supports liver regeneration by stabilizing HIF1α in bone-marrow-derived macrophages. (4:33)

A High-Salt Diet and Depression – A high-salt diet induces depression-like behavior symptoms in mice. (15:30)

A New Broad-Spectrum Antibiotic – The lasso peptide antibiotic lariocidin inhibits the bacterial ribosome. (29:10)

Boosting Antigen Cross-Presentation with STING – Researchers developed a new vaccine technology that stimulates CD8⁺ T cells and shows promise in mouse models of cancer and SARS-CoV-2 infection. (36:45)

Image courtesy of Dr. Monika Wolkers

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Ep. 102: “RNA-Binding Proteins” Featuring Dr. Monika Wolkers Apr 08, 2025
Show notes

Guest:

Dr. Monika Wolkers is a Group Leader at the Sanquin Blood Supply Foundation and an Associate Professor at the University of Amsterdam. Her research focuses on RNA-binding proteins and how they affect T cell function. She talks about γδ T cells in immunotherapy, targeting pediatric tumors, and how a sabbatical led her to study RNA-binding proteins. (46:50)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Macrophages in Liver Regeneration – Glutamate supports liver regeneration by stabilizing HIF1α in bone-marrow-derived macrophages. (4:33)

A High-Salt Diet and Depression – A high-salt diet induces depression-like behavior symptoms in mice. (15:30)

A New Broad-Spectrum Antibiotic – The lasso peptide antibiotic lariocidin inhibits the bacterial ribosome. (29:10)

Boosting Antigen Cross-Presentation with STING – Researchers developed a new vaccine technology that stimulates CD8⁺ T cells and shows promise in mouse models of cancer and SARS-CoV-2 infection. (36:45)

Image courtesy of Dr. Monika Wolkers

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

Ep. 101: “IMMUNOLOGY2025™” Featuring Drs. Stephen Jameson and Bonnie Dittel Mar 25, 2025
Show notes

Guests:

Dr. Stephen Jameson is the President of the American Association of Immunologists, and LMP Professor and Harry Kay Chairman’s Fund Professor in Experimental Pathology at the University of Minnesota Twin Cities. Dr. Bonnie Dittel is the Dr. Gilbert C. White II Endowed Faculty Chair at Versiti Blood Research Institute and Editor-in-Chief of ImmunoHorizons. In this episode, they talk about the upcoming IMMUNOLOGY2025 meeting in Honolulu, Hawaii from May 3-7, 2025. They discuss the highlights of the program, including the President’s Symposium and special sessions for new members. (36:07)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

H5N1 Antibody Responses – Older adults have partial immunity to H5N1 due to exposure to similar influenza strains earlier in life. (4:00)

Macrophages in Kidney Disease – Macrophage RGMb promotes kidney disease by increasing macrophage infiltration. (8:50)

Spatial Transcriptomics of Liver Cancer – A new spatial immune scoring system predicts the risk of recurrence of hepatocellular carcinoma. (18:20)

Neutrophils in the Skin – A population of neutrophils build extracellular matrix rings around wounds. (25:10)

Image courtesy of Drs. Stephen Jameson and Bonnie Dittel

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Never miss updates about new episodes.
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Ep. 101: “IMMUNOLOGY2025™” Featuring Drs. Stephen Jameson and Bonnie Dittel Mar 25, 2025
Show notes

Guests:

Dr. Stephen Jameson is the President of the American Association of Immunologists, and LMP Professor and Harry Kay Chairman’s Fund Professor in Experimental Pathology at the University of Minnesota Twin Cities. Dr. Bonnie Dittel is the Dr. Gilbert C. White II Endowed Faculty Chair at Versiti Blood Research Institute and Editor-in-Chief of ImmunoHorizons. In this episode, they talk about the upcoming IMMUNOLOGY2025 meeting in Honolulu, Hawaii from May 3-7, 2025. They discuss the highlights of the program, including the President’s Symposium and special sessions for new members. (36:07)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

H5N1 Antibody Responses – Older adults have partial immunity to H5N1 due to exposure to similar influenza strains earlier in life. (4:00)

Macrophages in Kidney Disease – Macrophage RGMb promotes kidney disease by increasing macrophage infiltration. (8:50)

Spatial Transcriptomics of Liver Cancer – A new spatial immune scoring system predicts the risk of recurrence of hepatocellular carcinoma. (18:20)

Neutrophils in the Skin – A population of neutrophils build extracellular matrix rings around wounds. (25:10)

Image courtesy of Drs. Stephen Jameson and Bonnie Dittel

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Never miss updates about new episodes.
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Peter Doherty — Ep. 100: “Viral Immunity” Featuring Dr. Peter Doherty Mar 11, 2025
Show notes

Guest:

Dr. Peter Doherty is Laureate Professor at the University of Melbourne. He and Dr. Rolf Zinkernagel, the co-recipient of the 1996 Nobel Prize in Physiology or Medicine, discovered how T cells recognize their target antigens in combination with major histocompatibility complex proteins. Beyond this, Dr. Doherty has made significant contributions to studying viral immunity, with a strong focus on how the immune system responds to influenza and other respiratory viruses.

In this episode, he talks about beginning his career as a veterinarian studying sheep and his seminal discoveries on the mechanisms of T cell antigen recognition. He also discusses his ventures into science communication. (38:08)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Microbes on the International Space Station – Researchers generated a 3D map of the microbes and metabolites on surfaces of the International Space Station. (3:40)

T Cell Specificity During Infection – Self-peptide-specific Treg cells promote self-nonself discrimination during infection. (9:15)

Skin Pathogens in Nursing Homes – Scientists investigated the genomic epidemiology of the multidrug-resistant Candida auris in a nursing home. (23:40)

Metabolic Recycling – Phagocytosed bacteria can serve as an alternative nutrient source for macrophages. (29:14)

Image courtesy of Dr. Peter Doherty

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Ep. 100: “Viral Immunity” Featuring Dr. Peter Doherty Mar 11, 2025
Show notes

Guest:

Dr. Peter Doherty is Laureate Professor at the University of Melbourne. He and Dr. Rolf Zinkernagel, the co-recipient of the 1996 Nobel Prize in Physiology or Medicine, discovered how T cells recognize their target antigens in combination with major histocompatibility complex proteins. Beyond this, Dr. Doherty has made significant contributions to studying viral immunity, with a strong focus on how the immune system responds to influenza and other respiratory viruses.

In this episode, he talks about beginning his career as a veterinarian studying sheep and his seminal discoveries on the mechanisms of T cell antigen recognition. He also discusses his ventures into science communication. (38:08)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

Microbes on the International Space Station – Researchers generated a 3D map of the microbes and metabolites on surfaces of the International Space Station. (3:40)

T Cell Specificity During Infection – Self-peptide-specific Treg cells promote self-nonself discrimination during infection. (9:15)

Skin Pathogens in Nursing Homes – Scientists investigated the genomic epidemiology of the multidrug-resistant Candida auris in a nursing home. (23:40)

Metabolic Recycling – Phagocytosed bacteria can serve as an alternative nutrient source for macrophages. (29:14)

Image courtesy of Dr. Peter Doherty

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Never miss updates about new episodes.
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add guest name — Ep. 99: “Inflammation and Innate Immunity” Featuring Dr. Luke O’Neill Feb 25, 2025
Show notes

Guest:

Dr. Luke O’Neill is a Professor and Chair of Biochemistry at Trinity College Dublin, where his research group is focused on exploring the molecular basis of inflammation. His lab endeavors to provide a better understanding of the metabolic regulation of immune cell function and the innate immune system, with the aim of developing novel therapies to treat inflammatory diseases.

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

A Phage Counter-Defense – An orphan antitoxin counter-defense element has been discovered in phages that can overcome a bacterial toxin-antitoxin phage defense system. (5:40)

Pathogenic Memory T Cells – Researchers uncover a pathogenic subset of CD8⁺ memory T-cells that promote tissue inflammation. (14:05)

The Role of Macrophages in Graft-Versus-Host Disease – Scientists show that IL-34 reprograms macrophages to mitigate gastrointestinal complications in GVHD. (23:41)

A New Treatment Path for Nerve Damage – Research suggests that macrophages may play a protective role in preventing neuropathy from developing. (30:19)

Image courtesy of Dr. Luke O’Neill

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Ep. 99: “Inflammation and Innate Immunity” Featuring Dr. Luke O’Neill Feb 25, 2025
Show notes

Guest:

Dr. Luke O’Neill is a Professor and Chair of Biochemistry at Trinity College Dublin, where his research group is focused on exploring the molecular basis of inflammation. His lab endeavors to provide a better understanding of the metabolic regulation of immune cell function and the innate immune system, with the aim of developing novel therapies to treat inflammatory diseases.

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria.

The Immunology Science Round Up

A Phage Counter-Defense – An orphan antitoxin counter-defense element has been discovered in phages that can overcome a bacterial toxin-antitoxin phage defense system. (5:40)

Pathogenic Memory T Cells – Researchers uncover a pathogenic subset of CD8⁺ memory T-cells that promote tissue inflammation. (14:05)

The Role of Macrophages in Graft-Versus-Host Disease – Scientists show that IL-34 reprograms macrophages to mitigate gastrointestinal complications in GVHD. (23:41)

A New Treatment Path for Nerve Damage – Research suggests that macrophages may play a protective role in preventing neuropathy from developing. (30:19)

Image courtesy of Dr. Luke O’Neill

Subscribe to our newsletter!

Never miss updates about new episodes.
Subscribe

Ep. 98: “IUIS 2025: Waltzing into the Future of Immunology” Featuring Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman Feb 11, 2025
Show notes

Guests:

Dr. Wilfried Ellmeier is a Co-Chair of the Scientific Planning Committee at the International Union of Immunological Societies (IUIS) and Professor of Immunobiology and Head of the Institute of Immunology at the Medical University of Vienna. Dr. Laurence Zitvogel is a Keynote Speaker at IUIS 2025 and a Professor and Group Leader at Gustave Roussy. Dr. Dan Littman is also a Keynote Speaker at IUIS 2025 and Professor of Cell Biology and Helen L. and Martin S. Kimmel Professor of Molecular Immunology at NYU Langone. This episode features a discussion on the upcoming IUIS 2025 Congress taking place August 17-22 in Vienna, Austria. They talk about what to expect at the meeting, highlights from this year’s program, and where to explore in Vienna. (42:25)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria!

The Immunology Science Round Up

An African Microbiome Atlas – A cross-sectional gut microbiome study sampled 1,801 women from Burkina Faso, Ghana, Kenya, and South Africa. (3:33)

Understanding Transplant Rejection – Inducing tolerance to immunodominant indirect CD4⁺ T cells prolongs graft survival. (7:38)

SARS-CoV-2 Evolution – A modeling approach predicts SARS-CoV-2 variant dynamics on the basis of immunity and cross-neutralization. (25:00)

Tregs in the Meninges – Meningeal Tregs are a multifaceted safeguard of brain homeostasis at steady state. (31:01)

Images courtesy of Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman

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Never miss updates about new episodes.
Subscribe

Ep. 98: “IUIS 2025: Waltzing into the Future of Immunology” Featuring Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman Feb 11, 2025
Show notes

Guests:

Dr. Wilfried Ellmeier is a Co-Chair of the Scientific Planning Committee at the International Union of Immunological Societies (IUIS) and Professor of Immunobiology and Head of the Institute of Immunology at the Medical University of Vienna. Dr. Laurence Zitvogel is a Keynote Speaker at IUIS 2025 and a Professor and Group Leader at Gustave Roussy. Dr. Dan Littman is also a Keynote Speaker at IUIS 2025 and Professor of Cell Biology and Helen L. and Martin S. Kimmel Professor of Molecular Immunology at NYU Langone. This episode features a discussion on the upcoming IUIS 2025 Congress taking place August 17-22 in Vienna, Austria. They talk about what to expect at the meeting, highlights from this year’s program, and where to explore in Vienna. (42:25)

Featured Products and Resources:

Register now for IMMUNOLOGY2025, taking place May 3-7 in Honolulu, Hawaii.

IUIS 2025 is taking place August 17-22 in Vienna, Austria!

The Immunology Science Round Up

An African Microbiome Atlas – A cross-sectional gut microbiome study sampled 1,801 women from Burkina Faso, Ghana, Kenya, and South Africa. (3:33)

Understanding Transplant Rejection – Inducing tolerance to immunodominant indirect CD4⁺ T cells prolongs graft survival. (7:38)

SARS-CoV-2 Evolution – A modeling approach predicts SARS-CoV-2 variant dynamics on the basis of immunity and cross-neutralization. (25:00)

Tregs in the Meninges – Meningeal Tregs are a multifaceted safeguard of brain homeostasis at steady state. (31:01)

Images courtesy of Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman

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Never miss updates about new episodes.
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