The Human Upgrade: Biohacking for Longevity & Performance

Latest Episodes:

How Fasting Resets Your Biology and Helps You Live Longer – Valter Longo, Ph.D., with Dave Asprey : 812 Apr 08, 2021

Show notes

In this episode of Bulletproof Radio, I’m talking with a godfather of fasting, Professor Valter Longo, Ph.D. He started researching fasting decades before anyone else started paying much attention to it. In 2018, TIME Magazine named Prof. Longo as one of the 50 most influential people in health care for his research on fasting-mimicking diets as a way to improve health and prevent disease.

He’s director of the Longevity Institute at University of Southern California-Leonard Davis School of Gerontology, Los Angeles, and director of the Longevity and Cancer Program at the Italian Foundation of Cancer Research.

“Fasting really in my mind is probably the most powerful way to reset and help regenerate, but also help clear junk and damage that is accumulated,” Prof. Longo says.

Our conversation hits the high points of how and why to fast, and also goes into the research that got us to what we know today and looks at what’s next. We talk about everything from Prof. Longo's foundational research on yeast to the possibility of having future technology that tells us how to fast based on certain blood markers or gut bacteria.

He’s also focused his work on the nutrients present in the fats, proteins and carbs we choose to consume during our fasts.

“Without understanding how nutrients such as proteins and sugars affect cellular function, aging and aging damage, and regeneration, it's difficult to determine the type and quantity of nutrients for optimal longevity,” Prof. Longo says in his book,“The Longevity Diet: Discover the New Science Behind Stem Cell Activation and Regeneration to Slow Aging, Fight Disease, and Optimize Weight.”

Beyond fasting, Prof. Longo created five pillars of longevity related to nutrition and human biology: juventology (the study of youth), epidemiology, clinical studies, centenarian studies, and the study of complex systems.

We also discuss bigger philosophical questions and the ethics surrounding longevity. What would it mean to try and live forever? And what does longevity mean in the face of advancing technology that may boost our life span by 50 to 100 years?

“I think technology is going to take over in the next 50 years and I think bionics is going to take over in the next 50 years,” Prof. Longo says. “It’s going to be a very different world; it’s going to be a very different approach. And it’s going to be an approach that has to do much more with memory and memory transfer, and all kinds of crazy things.”

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VIRTUAL BIOHACKING CONFERENCE MAY 8, 2021

Recharge Your Cells & Upgrade Your Life at this one-day event! Register at https://www.biohackingconference.com

UPGRADE YOURSELF EVEN MORE

Learn directly from Dave Asprey in his new membership group https://ourupgradecollective.com

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How to Get a Handle on Your Histamine – Dr. Becky Campbell with Dave Asprey : 811 Apr 06, 2021

Show notes

In this episode of Bulletproof Radio, you’re going to learn a lot you probably didn’t know about histamine. Turns out histamine is a major neurotransmitter that affects your awareness, food cravings, tiredness and inflammation. I’m talking with Dr. Becky Campbell, a board-certified doctor of natural medicine who focuses on histamine issues based on experiences from her patients and her own life.

Histamine is a very important part of the immune system and plays a role in inflammation in the body. We also need histamine in order to digest food, move our bowels, boost exercise performance, increase attention, and get blood as well as nutrients and oxygen delivered to different parts of the body. But things can go off track.

Histamine intolerance is not a sensitivity to histamine, but an indication that too much of it has built up in the body, or that there is an inability to break it down properly.

So, how could high histamine affect you?

“Migraines, passing out,” Dr. Campbell says. “Eating and having a really fast heart rate for no reason, having anxiety out of the blue for no reason. Any type of dermatitis, or hives, or flushing, random diarrhea, going from sitting to standing and getting dizzy. It's all over the place.”

Fatigue immediately after eating also can be an indicator. “My biggest symptom of histamine intolerance is fatigue,: Dr. Campbell says. “I would eat something that was supposedly healthy for me, like fermented food, and literally felt like I took a sleeping pill.”

It’s a natural response for our body to release histamine, but if we can’t break it down (which can happen from reduced enzyme activity, various gut issues, from vitamin deficiencies and more) it becomes a problem. She shares what foods to avoid and what foods to eat when you’re dealing with histamine intolerance.

The most common high histamine foods include pork, citrus, fermented foods, alcohol, and aged meats and cheeses. If you eat a high histamine food and your body isn’t prepared to break it down, the mast cells that produce it (and other inflammatory chemicals) can just pour it out into the body, resulting in a lot of inflammation.

Dr. Campbell estimates up to 40 percent of people could have some degree of histamine sensitivity. Vitamin C, quercetin and zinc can help.

If you know (or maybe are beginning to think) high histamine negatively affects you, Dr. Becky gives you some great tips so you can identify symptoms and histamine culprits in your diet, and start finding solutions.

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Bonus: ‘Energy’ featuring Dr. Barry Morguelan and Pedram Shojai Apr 02, 2021

Show notes

This episode focuses on energy with two masters dedicated to this work. You’ll hear highlights from their previous interviews with me to get an idea of their styles and areas of expertise.

I hope this preview inspires you to join me and thousands of others at the Virtual Biohacking Conference on May 8, 2021, to Recharge Your Cells & Upgrade Your Life. You’llhear brand new information from these two amazing guests and much more from all the guests who will be presenting.

Dr. Barry Morguelan is a world-class medical doctor and the only western Grand Master of a 5,000-year-old Chinese Source Energy discipline. For more than 20 years, he’s been supporting people through the Energy for Success program. He helps world leaders, entrepreneurs, health-care professionals, scientists, professional athletes, teachers, parents and people from all walks of life and various professions achieve success toward personally defined goals.

Pedram Shojai, a.k.a. The Urban Monk, is a Doctor of Oriental Medicine and master herbalist and acupuncturist. He’s also an acclaimed Qigong Master and Taoist Abbot with a practical approach to modern living. His most recent work, “FOCUS: Bringing Time, Energy and Money into Flow” brings your attention in line with your intention to get the life you want.

VIRTUAL BIOHACKING CONFERENCE MAY 8, 2021

“Recharge Your Cells & Upgrade Your Life” as you join me for a day of learning with expert guests, biohacking tips from beginner to advanced, access to a virtual tech hall, and more. Register at https://www.biohackingconference.com.

UPGRADE YOURSELF EVEN MORE

Learn directly from Dave Asprey in the new membership group https://ourupgradecollective.com.

DAVE ASPREY’S NEW BOOK

“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”

CONNECT WITH DAVE ASPREY

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Conquer Your Cycle at Every Age – Stephanie Estima, D.C., with Dave Asprey : 810 Apr 01, 2021

Show notes

Great In this episode of Bulletproof Radio, Dr. Stephanie Estima encourages women to start the process of owning their health by collecting data on their cycle. That way, women can start to understand their body’s individuality and work with it, not against it.

She’s a doctor of Chiropractic with expertise in female metabolism and body composition who joined me on the show to discuss her new book “The Betty Body: A Geeky Goddess’ Guide To Intuitive Eating, Balanced Hormones, And Transformative Sex.”

The term “Betty” originally came from the fans of her podcast “Better! With Dr. Stephanie,” but it ended up fitting just right for what she stands for as a woman and a doctor. As she says in her book: “Betty is a fully embodied force of nature. Her intuition knows what her body needs and how to attend to herself to nourish, not punish. A Betty is sexiness embodied.”

When you’re in the worst part of your cycle and feel irritable and/or exhausted, Dr. Stephanie says it can be a time to look inwards and re-evaluate how and why you feel the way that you do. You’ll learn about what phases of your cycle are best for what activities; like, what is the best time to do a HIIT workout? Conduct an interview? Launch a new project? Start fasting?

She also explains the ways keto and fasting can negatively impact women, most commonly through bad sleep and hair loss. She says women can manipulate three variables in fasting for more success: the type of fast, the length of fast and the frequency of fast. You learn why you have to pay attention to leptin resistance and what helps to fix keto for women.

“We often think that health is this really difficult full-time job that we all need to hire the personal trainer, and the body worker, and the nutritionist, and the chef,” she says. “Once we step into the intuitive nature that our bodies already have and begin to decode the signals, then you really become more attuned with your body rhythms and you'll be able to respond appropriately.”

Add in knowing your metabolic markers, focusing on muscle strength, and eating for nutritional needs, not calorie counting.

Dr. Stephanie shares a lot of knowledge we’ve never had on the show before, and she does it in a way that I find super empowering. Coronal plane exercises and brain health, anyone? Yep, you’ll learn that here, too. She does an incredible job encouraging women to own their period, and through that, their body and their powerful presence in the world.

Enjoy! And get more resources at Dave.Asprey/podcasts.

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VIRTUAL BIOHACKING CONFERENCE MAY 8, 2021

Recharge Your Cells & Upgrade Your Life at this one-day event! Register at https://www.biohackingconference.com

UPGRADE YOURSELF EVEN MORE

Learn directly from Dave Asprey in his new membership group https://ourupgradecollective.com.

DAVE ASPREY’S NEW BOOK

“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”

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Innovative Sex Toys Help Close the Pleasure Gap – Alexandra Fine with Dave Asprey : 809 Mar 30, 2021

Show notes

I talk about sex regularly on Bulletproof Radio because the energy, connection and humanity that’s a part of sexual wellness improves our lives. So does the fun factor.

In this episode, credentialed sexologist Alexandra Fine talks with me about the pleasure gap and ways to close it. After earning her master’s in Clinical Psychology with a concentration in sex therapy from Columbia University, she decided to focus her passion and expertise on the world of sex tech.

Alex and mechanical engineer Janet Lieberman co-founded Dame Products. These are innovative tools and resources for adult sexual well-being: solo play, couples or polyamorous if that’s your preference. Dame’s first product, Eva, became the most crowdfunded sex toy in history. Its second product, Fin, was the first sex toy allowed on Kickstarter.

“We are women designing products that predominantly help people just like us have more fulfilling lives,” Alex said about getting the Fin on Kickstarter. “This isn't about prurient behavior. This isn't about being lewd or crude. This is about living a healthy life.”

Beyond the obvious physical fun, Dame’s meticulously engineered vibrators designed to do three specific things:

start necessary conversations,
listen rather than assume, and
create products that enhance intimacy.

Within five years of its launch, Dame earned critical and popular acclaim, as well as praise in international media, including the New York Times, Forbes, Wired, Vice, BBC and the Today Show. Fast Company recognized Dame as one of the "most innovative wellness companies of 2020,” and Well+Good named Dame a “2020 changemaker.”

Listen on to learn more about how shame-free sex and well-designed sex toys can contribute to your overall health and energy.

More Sexual Health: My recent Sexual Energy Series spanned six episodes #787 to #792 featuring experts ranging from sexual fantasies to women’s health to the evolution of the penis. I’ve also covered tantric sex, orgasms, the psychology of sex and more with other guests through the years.

Enjoy! And get more resources at Dave.Asprey/podcasts.

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VIRTUAL BIOHACKING CONFERENCE MAY 8, 2021

Recharge Your Cells & Upgrade Your Life at this one-day event! Register at https://www.biohackingconference.com

WANT TO UPGRADE YOURSELF EVEN MORE?

Learn directly from Dave Asprey in his new membership group https://ourupgradecollective.com.

DAVE ASPREY’S NEW BOOK!

“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”

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Boost Your Oral, Dental & Throat Health with Probiotics – Prof. John Tagg with Dave Asprey : 808 Mar 26, 2021

Show notes

In this episode of Bulletproof Radio, we’re talking about bugs. The good kinds!

Emeritus professor and microbiologist John Tagg has been researching bacteria since the mid 1970s and has been specifically looking for a probiotic solution to Group A Strep. He’s done this work primarily at the Department of Microbiology and Immunology at the University of Otago in Dunedin, New Zealand. He’s responsible for the isolation and characterization of the first streptococcal bacteriocin and wrote the first major review of the bacteriocins of gram-positive bacteria.

Prof. Tagg’s pioneering research led to the discovery of two probiotic bacterial strains. These strains of 'friendly' bacteria are effective in crowding out bad bacteria in the mouth. Both are strains of S. salivarius, which are naturally found in the oral cavity of healthy humans.

One is the world’s first oral probiotic strain from the mouth for the mouth.
The other probiotic strain specifically targets dental and gum health.

Most people don’t have very much of either of these beneficial strains, so a daily supplement is a great way to boost the good bacteria in the mouth to help with throat health, teeth and gum health and bad breath. Prof. Tagg partners with BLIS Technologies to create supplements for throat, dental and oral health.

"The real importance is that the mouth is the portal of entry of most microbes, good or bad, for the human body," says Prof. Tagg. "We have our skin microflora, of course. But I believe that by focusing attention on having a healthy and protective oral microbiota, you cannot only sort of interfere, you can delay or divert infections or disease of the oral cavity, then it can have a flow on effect also to the gut."

You’re going to learn a lot of new information about good bacteria and probiotics from an expert who’s dedicated decades of time, authored more than 230 research publications on the topic and isolated over 2,000 bacterial strains.

Enjoy! And get more resources at Dave.Asprey/podcasts.

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A New Way to Control Your Blood Sugar – BiOptimizers with Dave Asprey : 807 Mar 25, 2021

Show notes

Great PodMonitoring your blood sugar is one of the most important interventions you can make for yourself in order to live long and truly feel good.

If you have diabetes, your cardiovascular disease risk, your cancer risk and your Alzheimer's risk all go up dramatically.

So, what if we were to just put on our thinking hats as biohackers and say, "Which intervention has the highest ROI for reducing my odds of dying from everything?" Regulating your blood sugar would be very, very high on the list, probably more important than exercise, even though exercise can be a method of controlling your blood sugar and exercise and movement are important, no doubt about it. If you didn't move around and your blood sugar was highly regulated, you'd be better off than if you had irregular blood sugar and you moved around. It's that big of a deal.

In this episode of Bulletproof Radio, Wade Lightheart and Matt Gallant are back on the show. This time, they’re letting you know how to get control of your blood sugar spikes and drops, and instead find a stable middle ground.

These two BiOptimizers cofounders have decades of combined experience in health, nutrition and exercise. They really get how the brain and body work together for maximum performance and realize so much of that has to do with our blood sugar.

“Our pancreases are both four and a half times the size per body weight of any species on the planet because we eat so much sugar,” Matt says. “That's what involved in the regulation and distribution of insulin.”

If you don’t manage your blood sugar, there will be consequences. But when you find a way to maintain stable glucose levels, your body learns how to convert glucose into energy more effectively. This leads to better performance. Your body repairs and you have more energy for thinking and moving.

We talk about ketones, carbs and how to keep your blood sugar at a consistent level (even when you have those days where you eat a 4,000 calorie meal). You’ll also learn how you can best collect data on what works for your body and how the active ingredients work in BiOptimizer’s Blood Sugar Breakthrough supplement.

“As great as our product is and it's really awesome, I want to also caution people,” Wade says. “You can't supplement your way out of a bad diet, and you want to take data, and you want to correlate it with biofeedback.”

Enjoy! And get more resources at Dave.Asprey/podcasts.

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WANT TO UPGRADE YOURSELF EVEN MORE?

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“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”cast

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How Fitness Saved a Life and Became a Livelihood – Doug Bopst with Dave Asprey : 806 Mar 23, 2021

Show notes

In this episode of Bulletproof Radio my guest shares an inspiring life story about addiction, adversity and resilience.

Doug Bopst is an award-winning personal trainer, author, speaker and host of the Adversity Advantage podcast. His journey traverses a difficult childhood, an addiction spiral and time in jail.

He credits a judge, a cell mate, and unexpectedly finding faith with 12 years of sobriety and his ability to help others change and reclaim their own lives.

His transformation started with fitness in jail to help him recover from drug addiction. Exercise changed his body, his state of mind and his ability to continuously show up for himself.

“I was finally able to get comfortable being uncomfortable,” Doug says. “I was finally able to face my fears and face my emotions, really, head on, and learn to channel a lot of that pain into something good.”

Post-jail time, he found new ways to manage his emotions. Where before he would have used drugs to respond to negative thoughts and feelings, he began relying on exercise, which built up his self-confidence.

“When I was working out, it wasn't necessarily as much to get in shape as it was for me to relearn how to deal with my emotions in a way that was conducive to who I wanted to become,” Doug says.

Doug also shares how his self-support system developed over time, and the importance of a full healthy lifestyle, not just a good fitness routine. For him, feeling good isn’t just about exercise, but a network of family, faith, therapy, meditation and eating right.

He encourages the people that he trains to find their own version of a full, healthy life. No one thing can be a solution, but instead it’s all a part of journey of self-forgiveness, healing and finding the things that feel good for you.

“A lot of this stuff that I've been doing is simply to help people, give people hope, whether that's somebody who's struggling with addiction, whether that's a parent, whether that's somebody who's just struggling to feel better about themselves,” Doug says. “That's my main mission right now.”

Enjoy! And get more resources at Dave.Asprey/podcasts.

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WANT TO UPGRADE YOURSELF EVEN MORE?

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Mini-Episode: Cool Facts Friday #9 Mar 19, 2021

Show notes

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Enjoy!

Here’s the current lineup for episode #9:

Sleep may pre-date brain activity.
Genes could contribute to daytime nap needs.
Dopamine links aerobic fitness and cognition.
Eat bad food as a kid; pay the price into adulthood.
Green light relief for migraines.

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Self-Heal with Intermittent Fasting & Inner Bonding – Margaret Paul, Ph.D., with Dave Asprey : 805 Mar 19, 2021

Show notes

In this episode of Bulletproof Radio, we find out how my guest, 81-year-old Margaret Paul, Ph.D., has sustained intermittent fasting (IF) for more than 50 years!

Although IF may be a newer concept with regard to health and wellness, research has been happening for decades. And some people have been following IF for that long because it works for their own biology.

“I started intermittent fasting when I was about 30,” Margaret says. “And it's been fantastic in my life. I started learning about food in my early 20s, because I was a sickly kid, and I just didn't want to be sick. … I'm grateful that I found out about intermittent fasting before it was even a word. I mean, they didn't call it that then, but that's what it was.”

She was ahead of her time with fasting and also with the inner emotional, mental and spiritual work that rounds out a healthy life.

She’sa bestselling author and popular MindBodyGreen writer. She holds a Ph.D. in psychology, is a relationship expert, public speaker, consultant and artist. Her latest book is “Diet For Divine Connection: Beyond Junk Foods and Junk Thoughts to At-Will Spiritual Connection.”

“My brain is very sharp. I've worked probably at this point 60 hours a week. I'm highly creative,” she says. “I love my work. I've been doing it for a very long time, and I have no desire to slow down.”

Margaret co-created the powerful Inner Bonding® self-healing, six-step process. This program guides people through finding and defining their own inner worth. It allows you to let go of your wounded-ego voice that tells you you’ll never be good enough and instead operate from a higher connection of love and truth.

“If you don't know how to love yourself, you don't get filled up with love, you don't have anything to share,” Margaret says. “So, you're always trying to get it. Get the love, get the approval, get the attention. Inner Bonding® is about teaching you how to do that for yourself, so that you can share that with others.”

Margaret talks about ways people abandon themselves on an emotional level, like staying in their head and disconnecting from their body, judging themselves, blaming others and numbing out with addictions. During this episode, she shares how you can move beyond these patterns, access your internal higher guidance, and maintain a level of higher frequency with inputs like healthy organic foods and the practice of self-love.

Enjoy! And get more resources at Dave.Asprey/podcasts.

Got a comment, idea or question for the podcast? Submit via this form.

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!

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WANT TO UPGRADE YOURSELF EVEN MORE?

Learn directly from Dave Asprey in his new membership group https://ourupgradecollective.com.

DAVE ASPREY’S NEW BOOK!

“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.