The Human Upgrade: Biohacking for Longevity & Performance

Latest Episodes:

How Google X’s Mo Gawdat Made 1 Billion People Happier - Including YOU (Part 1) : 1230 Dec 10, 2024

Show notes

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How.

I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works.

Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy.

Mo dives into the raw science behind happiness and stress—revealing how your brain runs on algorithms that you can actually reprogram. Discover why dopamine might be sabotaging your joy, how to decode the four types of stress, and biohacks that can flip the script on your mental and physical resilience.

He also shares the deeply personal story of how he turned unimaginable tragedy into a global mission for happiness and purpose. Mo’s insights will challenge everything you thought you knew about living a fulfilled life.

What You’ll Learn:

• The happiness algorithm—and how to make it work for you

• Why dopamine addiction is robbing you of joy (and how to fix it)

• The four stress modalities and how to regain control

• Biohacks that build resilience—like cold plunges, gratitude, and micro-habits

• How small mindset shifts can create major life transformations

And don’t miss Part 2, dropping in two days! Dave and Mo explore the intersection of happiness and AI, revealing how to get them both working FOR you instead of against you.

Resources:

2025 Biohacking Conference – https://biohackingconference.com/2025

Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW

Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O

Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/

Danger Coffee – https://dangercoffee.com

Dave Asprey’s Website – https://daveasprey.com

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

Dave Asprey’s Linktree – https://linktr.ee/daveasprey

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

Own an Upgrade Labs – https://ownanupgradelabs.com

Upgrade Labs – https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com

Sponsors:

Neurohacker | Go to https://qualialife.com/dave and use code Dave for 15% off.

Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

Timestamps:

00:00 – Intro

00:31 – Introduction to The Human Upgrade

00:45 – Dave Asprey’s AI Background

01:13 – Introducing Mo Gawdat and His Work

01:51 – From Scary Smart to Unstressable

02:40 – The Journey to Happiness

13:10 – Understanding Stress and Its Mechanisms

17:26 – The Four Modalities of Stress

24:16 – Mental Stress and the Happiness Flowchart

31:34 – Sources of Stress: Trauma, Obsessions, Noise, and Nuisances

33:27 – Understanding Modern PTSD

34:09 – The Role of Obsessions and Noise

36:24 – Biohacking for Resilience

37:58 – The Power of Gratitude

40:12 – The Happiness Equation

54:37 – Dopamine vs. Serotonin

01:03:00 – The Benefits of Cold Therapy

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is Red Meat the Fountain of Youth? Paul Saladino : 1229 Dec 05, 2024

Show notes

Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit?

Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better outcomes. Together, he and Dave challenge assumptions about long-term ketosis, examine its potential downsides, and explore how to optimize diets for energy, gut health, and longevity.

They also tackle controversial topics like the risks of seed oils, the overhyped reputation of “health foods” like quinoa, and the critical roles insulin and nutrient density play in overall wellness. With insights on balancing mTOR, managing omega fats, and incorporating organ meats, this episode offers a nuanced perspective for anyone interested in biohacking, nutrition science, or simply eating smarter.

What you’ll learn:

• Why metabolic flexibility matters more than strict diet rules

• The science behind long-term ketosis and insulin’s broader role in health

• How common “health foods” could be doing more harm than good

• The importance of nutrient-dense animal-based foods for gut and immune health

• How to achieve optimal balance between fat types, mTOR, and longevity markers

Resources:

2025 Biohacking Conference – https://biohackingconference.com/2025

Shop Paul Saladino’s Products – https://heartandsoil.co

Follow Paul Saladino on Instagram – https://www.instagram.com/paulsaladinomd/

Paul Saladino’s Book: The Carnivore Code – https://www.amazon.com/Carnivore-Code-Unlocking-Returning-Ancestral/dp/035846997X

Lineage Provisions – 100% Grass-Fed Beef Tallow – https://lineageprovisions.com/products/100-grass-fed-beef-tallow

Danger Coffee – https://dangercoffee.com

Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

Dave Asprey’s Website – https://daveasprey.com

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

Dave Asprey’s Linktree – https://linktr.ee/daveasprey

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

Own an Upgrade Labs – https://ownanupgradelabs.com

Upgrade Labs – https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com

Sponsors:

- Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.

- LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave.

Timestamps:

• 00:00 Intro

• 00:40 Paul Saladino’s Evolution in Diet

• 01:21 Challenges of a Strict Carnivore Diet

• 03:36 Reintroducing Carbohydrates

• 05:32 Debunking Common Diet Myths

• 13:49 The Problem with Calorie Restriction

• 18:30 The Importance of Food Quality

• 24:08 The Veganism Debate

• 34:15 The Benefits of Organ Meats

• 37:27 Foot Surgery and Bone Density

• 39:23 Mineral Deficiency and Plant-Based Diets

• 40:00 The Truth About Seed Oils

• 41:10 Historical Studies on Seed Oils

• 47:26 Mechanisms and Effects of Seed Oils

• 52:33 Nicotine and Neuroprotection

• 54:12 Oleic Acid and Longevity

• 01:01:44 The Benefits of Animal Fats

• 01:02:32 Odd Chain Fatty Acids and Health

• 01:11:07 Cheese and Dairy Considerations

• 01:13:11 The Impact of Cheese on Health

• 01:14:03 Protein Intake and Longevity

• 01:14:54 Understanding mTOR and Its Effects

• 01:17:35 Ideal Body Fat and Metabolic Health

• 01:24:38 The Role of Omega Fatty Acids

• 01:32:46 ApoB, Insulin Sensitivity, and Longevity

• 01:43:09 Final Thoughts and Product Recommendations

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Why is your Oral Health KILLING you, and what can you do about it?! Naveen Jain : 1228 Dec 03, 2024

Show notes

What are the oral hygiene tips that could save your life?

Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks.

Discover why oral health goes far beyond brushing and flossing, how to optimize your oral microbiome for longevity, and why common mouthwashes may be doing more harm than good. Naveen also introduces cutting-edge solutions from Viome, including personalized oral lozenges and postbiotics, to elevate both your oral and overall health.

In this episode, you’ll also uncover the exact foods to eat and avoid to live a longer, healthier, and more vibrant life.

What you’ll learn in this episode:

• The surprising link between your oral microbiome and chronic disease

• Why bacterial diversity in your mouth is essential for overall health

• How leaky gums drive systemic inflammation and increase health risks

• The dangers of over-sterilizing your mouth and eliminating beneficial bacteria

• Personalized solutions to improve oral and gut health with Viome

• Actionable tips to optimize your oral microbiome for better longevity

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Viome Full Body Intelligence Test (Save $110) – https://www.viome.com/dave

• Viome Instagram – https://www.instagram.com/viome

• Learn More About Viome – https://viome.com

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Sponsors:

-Leela Quantum | Head to https://leelaq.com/DAVE for 10% off.

-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.

Timestamps:

• 00:00 Introduction to Viome and Its Impact on Health

• 00:53 Meet Naveen Jain: Visionary Behind Viome

• 02:41 Understanding the Microbiome and Its Role in Health

• 05:54 The Power of RNA Analysis in Personalized Health

• 12:19 Diet, Microbiome, and Personalized Nutrition

• 29:50 The Importance of Oral and Gut Health

• 39:20 Debating the Benefits of Intermittent Fasting

• 40:08 The Role of Gut Bacteria in Fasting and Diet

• 42:12 Understanding Chronic Inflammation and Diet

• 44:13 The Keto Diet Myths and Realities

• 45:44 Oxalates and Superfoods What You Need to Know

• 49:25 The Concept of Holobiont and Human Health

• 56:21 The Five Pillars of Longevity

• 01:02:04 The Importance of Quality Sleep

• 01:05:18 Purpose and Community for a Longer Life

• 01:09:48 Upcoming Topics and Final Thoughts

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What You DON'T Know About Women’s Health! From Microbiome to Major Impact with Priyanka Jain : 1227 Nov 28, 2024

Show notes

Is this the missing link in fertility?

The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes.

Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic research and AI-powered insights, offering solutions to challenges like bacterial vaginosis, yeast infections, recurrent UTIs, and even infertility. You’ll learn why this critical microbiome plays such a vital role, how hormonal changes and lifestyle impact it, and how personalized approaches can improve reproductive and overall health.

This episode explores not just women’s health but also how understanding the vaginal microbiome can influence relationships, biohacking, and even groundbreaking fertility research. Don’t miss this deep dive into the science and solutions shaping the future of health.

Here’s what you’ll learn in this episode:

• The critical role the vaginal microbiome plays in women’s health and fertility

• How hormonal changes affect vaginal health and microbiome balance

• The link between vaginal microbiome imbalances and conditions like bacterial vaginosis, yeast infections, and UTIs

• Evvy’s innovative approach to using AI and genomics for personalized health insights

• Practical tips for maintaining microbiome health, including probiotics, hydration, and hormone balance

• The connection between the vaginal microbiome and overall quality of life

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Shop at Evvy (Use coupon code DAVE for $10 off!) – https://shareasale.com/r.cfm?b=1862577&u=2810239&m=116251&urllink=&afftrack=

• Follow Evvy on Instagram – https://www.instagram.com/evvy

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Sponsors:

- Calroy | Head to https://calroy.com/dave for an exclusive discount.

Timestamps:

• 00:00 Trailer

• 00:35 Introduction to Vaginal Microbiome

• 01:12 Meet Priyanka Jain of Evvy

• 02:03 Understanding the Vaginal Microbiome

• 04:37 Challenges in Women’s Health

• 09:55 Impact of Lifestyle on Vaginal Health

• 11:22 The Role of Diet and Supplements

• 15:24 Sexual Health and Vaginal Microbiome

• 27:25 Menopause and Vaginal Health

• 31:23 Optimizing Vaginal Health

• 39:31 Exploring Women’s Health Data

• 41:17 The Role of Vaginal Microbiome in Fertility

• 43:44 Affordable Testing and Discount Offers

• 45:31 The Impact of Lubricants on Vaginal Health

• 46:20 Innovative Ideas for Probiotic Products

• 47:29 Audience Questions and Precision Medicine

• 48:04 The Importance of Data in Women’s Health

• 54:31 Marketing and Misinformation in Vaginal Health

• 01:06:34 The Connection Between Diet and Vaginal Health

• 01:12:49 Conclusion and Final Thoughts

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The World’s BEST Alcohol Alternative. Pleasure, Relaxation, and Clarity with TRU KAVA : 1226 Nov 26, 2024

Show notes

Is alcohol losing its grip as the go-to social drink?

Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity.

In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why kava is becoming the drink of choice for those seeking a healthier, more connected lifestyle. Learn how kava impacts neurotransmitters like GABA and dopamine, enhances creativity and emotional grounding, and even helps the body recover from stress and trauma. Discover why kava is taking center stage in the biohacking and sober-curious movements as a new tool for wellness and connection.

Here’s what you’ll learn in this episode:

• Why 41% of Americans and 61% of Gen Z are drinking less alcohol

• What kava is, how it works, and its history as a ceremonial and social beverage

• The science behind kava’s calming and neuroprotective effects

• How kava supports creativity, emotional resilience, and authentic social connection

• Practical uses for kava, including stress relief, sleep enhancement, and travel recovery

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• TRU KAVA – https://www.trukava.com

• TRU KAVA Instagram – https://www.instagram.com/trukava

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Sponsors:

-Quantum Upgrade |Go to https://quantumupgrade.io/Dave for a free trial.

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.

Timestamps:

• 00:00 Intro

• 00:37 Introduction to Alcohol Trends

• 01:57 Meet Cameron George and TRU KAVA

• 02:29 What is Kava?

• 05:03 Kava’s Effects on the Brain

• 06:53 Kava vs. Alcohol

• 08:54 Active Compounds in Kava

• 10:10 Kava’s Safety and Standardization

• 16:17 Kava in Social Settings

• 21:28 Kava and Psychedelics

• 31:26 Kava for Public Speaking and Anxiety

• 34:04 Kava in the Workplace: Enhancing Team Creativity

• 35:22 Kava and Libido: The Unexpected Benefits

• 36:06 Biohacking with Kava: Energy Allocation and Community

• 39:00 Kava’s Role in Meditation and Emotional Awareness

• 42:04 Kava During Pregnancy: Safety and Traditions

• 44:37 Kava’s Neuroprotective Properties: A Deep Dive

• 45:49 Kava and EMF Sensitivity: A Surprising Connection

• 48:39 Kava for Frequent Travelers: Enhancing Mitochondrial Health

• 52:46 Kava and Metabolic Health: Fasting and Fat Burning

• 57:14 Kava Products: Oils, Beverages, and Their Uses

• 01:01:27 The Future of Kava: Social Impact and Cultural Integration

• 01:05:28 Conclusion: The Potential of Kava in Modern Society

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Urolithin A’s Secret to YOUTHFUL ENERGY and the Fight Against Inflammaging : 1225 Nov 22, 2024

Show notes

Have we finally discovered the key to youthful energy, longevity, and cellular health?

In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation.

This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity.

Here’s what you’ll learn in this episode:

• What Urolithin A is and its role in mitochondrial health and cellular energy production

• How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking

• The connection between mitochondrial dysfunction and immune system aging

• Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity

• Why mitochondrial support is critical for combating aging and improving overall performance

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Timeline Nutrition - https://www.timeline.com/dave to get 10% off your first order

• Timeline Instagram – https://www.instagram.com/timeline_longevity/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Timestamps:

• 00:00 Introduction to Longevity and Mitochondria

• 01:28 The Role of Mitochondria in Immune Health

• 03:36 Understanding Inflammaging and Immune Aging

• 07:47 Measuring Immune Health and Inflammation

• 13:33 Urolithin A: A Mitochondrial Booster

• 16:46 Dosage and Effects of Urolithin A

• 26:11 Urolithin A and Exercise Performance

• 28:31 Urolithin A for Skin Health

• 31:34 Collagen and Aging: The Role of MMPs

• 33:27 Personal Experience with MMPs and Recovery

• 35:04 Measuring MMPs and Their Impact on Longevity

• 36:18 Skin Health and Urolithin A

• 38:39 Exploring Urolithin A’s Broader Benefits

• 40:33 Brain Health and Urolithin A

• 43:33 Combining Supplements for Optimal Health

• 45:54 Omega-3s and Mitochondrial Health

• 46:51 Ketones, MCTs, and Urolithin A

• 54:30 Final Thoughts on MitoPure and Supplementation

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Exosomes vs Stem Cells and LIFE-CHANGING Advice with Harvard Physician Dr. Edward Park : 1224 Nov 21, 2024

Show notes

Are exosomes the planet’s ultimate healing tool?!

In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing, explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells.

BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights into life, resilience, and emotional well-being, offering advice that goes far beyond medicine. From the power of forgiveness to breaking free of limiting beliefs, his perspective blends science, spirituality, and practical wisdom for living a better life.

Here’s what you’ll learn in this episode:

• How exosomes work and why they’re being called the future of regenerative medicine

• The key differences between exosomes and stem cells—and which is better for healing

• Real-life applications of exosome therapy for injuries, anti-aging, and overall health

• The potential of exosomes to enhance brain function, reduce inflammation, and promote recovery

• Dr. Park’s advice on emotional resilience, gratitude, and creating lasting change

With over a decade of experience, Dr. Park shares compelling case studies, cutting-edge insights, and practical advice for anyone looking to upgrade their body, mind, and life. Whether you’re managing chronic pain, exploring anti-aging therapies, or seeking wisdom for navigating life’s challenges, this episode has something for everyone.

Sponsors

TRU KAVA | Go to https://trukava.com and enter code DAVE15 at checkout for 15% off

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Dr. Edward Park’s Website: Recharge Biomedical – https://www.rechargebiomedical.com

• Dr. Edward Park’s Book: Exosomes: Songs of Healing – https://www.amazon.com/EXOSOMES-Songs-Healing-Ed-Park/dp/098260632X

• Dr. Edward Park’s YouTube Channel – https://www.youtube.com/channel/UCpp9DlRArB1rKAWNwoouiTg

• Dr. Edward Park on Instagram – https://www.instagram.com/dredpark/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Timestamps:

• 00:00 Introduction to Exosomes and Healing

• 00:48 Understanding Exosomes: Stem Cell Communication

• 01:19 Dr. Edward Park’s Insights on Exosomes

• 02:47 Exosomes vs. Traditional Treatments

• 04:44 Exosomes in Regenerative Medicine

• 07:33 Cost-Effective Regeneration Protocols

• 12:35 Exosomes for Hair Growth

• 14:37 Stem Cells and Brain Health

• 25:33 Banking Stem Cells for Future Use

• 35:27 Epigenetic Age and Longevity Predictors

• 37:48 CRISPR and Gene Editing: Risks and Benefits

• 39:43 Basic Health Tips for Longevity

• 41:02 Spirituality, Past Lives, and Healing

• 42:50 Questioning Medical and Political Narratives

• 47:54 The Importance of Free Speech

• 01:07:40 The Role of Intuition in Medicine

• 01:09:22 Conclusion and Final Thoughts

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is Infrared Light the KEY to Longevity? Detox, Recovery, and Increased Energy with Sunlighten Saunas : 1223 Nov 19, 2024

Show notes

Is biohacking your sweat the secret to vitality?

Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level.

Here’s what you’ll learn in this episode:

• Why infrared saunas excel at detoxing heavy metals and toxins

• How they mimic exercise to boost cardiovascular health and recovery

• The science behind infrared’s impact on mitochondrial energy and longevity

• Surprising benefits for gut health, inflammation, and hormone balance

• Hacks to get the most out of your infrared sauna sessions

Connie shares cutting-edge research and personal insights, offering practical ways to integrate infrared therapy into your routine. Whether you’re looking to recover faster, improve your mood, or support long-term health, this episode delivers the tools you need to take your biohacking game to the next level.

Special Offer: Use code “DAVE” at sunlighten.com to get up to $1,000 off until December 6th!

Sponsors:

-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.

-fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.

Resources:

• Sunlighten Saunas Website – https://www.sunlighten.com/dave/?utm_source=DaveAsprey&utm_medium=Partner&utm_content=Podcast&leadsource=DaveAsprey&utm_campaign=DaveAsprey

• Sunlighten Saunas on Instagram – https://www.instagram.com/sunlightensaunas/

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Timestamps

• 00:00 Introduction to Infrared Saunas

• 00:27 Meet Connie Zack: Leading Voice in Infrared Saunas

• 00:50 The Science Behind Infrared Saunas

• 02:35 Infrared Saunas vs. Traditional Saunas

• 05:41 Health Benefits of Infrared Saunas

• 08:14 Technological Advancements in Infrared Saunas

• 17:36 The Role of LEDs in Infrared Saunas

• 22:37 Practical Tips and Personal Experiences

• 28:14 Detoxing and Energizing with Glutathione

• 28:40 Pre and Post-Sauna Rituals

• 29:05 Habit Stacking in the Sauna

• 29:41 Managing Overheating Devices

• 31:05 Creative Breakthroughs in the Sauna

• 32:14 Scientific Method and Personal Experience

• 36:05 Understanding Glucose Spikes

• 38:44 Longevity Benefits of Infrared Saunas

• 43:27 Infrared Saunas and Skin Health

• 45:29 Extreme Detox Protocols

• 48:28 Grip Strength and Longevity

• 50:34 Customizing Your Sauna Experience

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How to Discover What You TRULY Want—and Ask for It! Featuring the Author of Dave’s Top Book for Women : 1222 Nov 14, 2024

Show notes

What if you could command any room and set boundaries without saying a word?

Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across disciplines like Medical Qi Gong and Systemic Constellations.

Here’s what you’ll learn in this episode:

• How to set clear, unbreakable boundaries in any situation

• Techniques for wielding influence without sacrificing integrity

• Tools to reclaim inner authority and navigate life with confidence

• Practical strategies for handling power dynamics in relationships, work, and beyond

Kasia’s methods have empowered over 4,000 women worldwide to step into leadership roles in every sphere, from personal relationships to professional arenas. In this episode, she shares practical insights on transforming how you’re perceived by others and, more importantly, how you perceive yourself. Whether you’re navigating complex workplace dynamics, strengthening personal boundaries, or seeking clarity in relationships, Kasia’s teachings offer a path to reclaiming the powerful, authentic authority within you.

Sponsors

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.

-LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave.

Resources:

• 2025 Biohacking Conference – https://biohackingconference.com/2025

• Kasia Urbaniak’s Website – https://www.kasiaurbaniak.com

• Kasia Urbaniak’s Book: Unbound: A Woman’s Guide to Power – https://www.kasiaurbaniak.com/unbound

• The Academy – Practical Training for Women on Power and Influence – https://www.kasiaurbaniak.com/the-academy

• Kasia Urbaniak on Instagram – https://www.instagram.com/kasiaurbaniak/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Timestamps:

• 00:00 Introduction to the Human Upgrade

• 01:07 Meet Kasia Urbaniak: Author of Unbound

• 02:52 Exploring Power Dynamics

• 04:46 The Role of Emotions in Power

• 14:50 Embodiment and Somatic Work

• 32:58 The Power of Voice and Presence

• 48:22 Collective Intelligence and Intuition

• 54:50 Facing Fears and Intuition

• 55:15 Male vs. Female Intuition

• 56:01 The Power of Erotic Energy

• 57:13 Welcoming Emotions and States

• 59:10 Role-Playing and Personas

• 01:00:06 Teaching Women to Speak Up

• 01:02:04 Energetic Dynamics in Relationships

• 01:04:35 Victimhood and Healing

• 01:19:54 The Power of Asking

• 01:29:40 Money and Emotional Alchemy

• 01:31:53 Shameless Money Conversations

• 01:44:00 Final Thoughts and Upcoming Events

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How to Optimize Your Brain for WORK: Achieving Hyper-Efficiency with Dr. Mithu Storoni : 1221 Nov 12, 2024

Show notes

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless?

In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments.

Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output.

Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day.

Sponsors

-Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

-Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.

Resources:

• Dr. Mithu Storoni’s Website – https://www.mithustoroni.com

• Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storoni – https://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/

• Dr. Mithu Storoni on Facebook – https://www.facebook.com/drmithustoroni/

• Dr. Mithu Storoni’s LinkedIn – https://www.linkedin.com/in/mithu-storoni-0488872a/

• Dave Asprey’s Website – https://daveasprey.com

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books

• Danger Coffee – https://dangercoffee.com

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com

• Own an Upgrade Labs – https://ownanupgradelabs.com

• Upgrade Labs – https://upgradelabs.com

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com

Timestamps

• 00:00 – Introduction to Brain Complexity

• 00:29 – The Human Upgrade with Dave Asprey

• 01:42 – Meet Dr. Mijtu Storoni

• 02:16 – Understanding Brain Efficiency

• 02:57 – The Role of Astrocytes

• 04:37 – Brain Adaptability and Environment

• 06:55 – Biohacking and Environmental Signals

• 08:34 – Power vs. Efficiency Debate

• 11:26 – The Importance of Glial Cells

• 18:10 – The Brain as a Predictive Machine

• 23:14 – Nutrition and Brain Health

• 32:33 – The Gut-Brain Connection

• 36:36 – Eye Health as a Proxy for Brain Health

• 40:47 – Aligning the Brain: The Blue Dot Network

• 41:54 – Understanding Brain Gears and Stress Management

• 42:27 – Maintaining the Goldilocks Zone for Optimal Brain Function

• 43:09 – The Role of Creativity and Daydreaming

• 44:28 – Strategies to Stay in Optimal Mental States

• 47:44 – Biohacking for Enhanced Efficiency

• 51:00 – The Science Behind Flow States

• 57:09 – Harnessing Innate Curiosity for Mental Efficiency

• 01:03:46 – Breathing Techniques for Mental Regulation

• 01:13:32 – The Importance of Ultradian Rhythms

• 01:17:40 – Practical Tips for Efficient Breaks

• 01:21:20 – Conclusion: Embracing Hyper Efficiency

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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