Physionic

Latest Episodes:

Excessive Exercise changes how our Mitochondria behave? [Mitochondrial Dynamics] 2 Apr 07, 2021

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In this episode, we finish up from last week by discussing how mitochondrial "behavior" is affected by excessive exercise, as well as its impact on mitochondrial reactive oxygen generation, which can cause damage to our cells.
Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub
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Is too much exercise detrimental to our mitochondria and blood sugar regulation? Mar 31, 2021

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In this episode, I cover a brand spankin' new study wherein the researchers attempt to answer the question of overdoing exercise and its impact on muscle mitochondria, as well as blood sugar regulation.
Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub
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Weight Loss and its affect on Metabolic Adaptation Mar 24, 2021

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In this episode, we take a look at a study that investigates the impact weight loss/calorie restriction has on metabolic adaptation; we also briefly discuss the idea of metabolic "damage". This is one of a few episodes that I'll be using to cover the topic of metabolic adaptation.
Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328781/?fbclid=IwAR3WSvSpNLzgnwfGh_xyAEx4Txh9z91LnjbW2CFrbbzSS0cM-47MGL4eUxU
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Ketogenic Diet & Ketosis leads to Heart Cell Death [Study Breakdown] Mar 17, 2021

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In this episode, I take us on a brief breakdown of a study looking at the ketogenic diet and its impact on heart cell death, heart size, and mitochondrial content. Some intriguing, potentially alarming, results here, but we'll see what interpretations we can really make on this data - dive in with me!
Study: https://www.nature.com/articles/s41392-020-00411-4
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Burning More Fat DOES NOT mean losing more BODY FAT Mar 10, 2021

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In this episode, I attempt to make it as clear as possible, by comparison of high fat/keto to high carbohydrate diets and how they differ in their ability produce body fat loss, although one promotes greater fat burning/oxidation.
Video Podcast (available at 10am ET): https://youtu.be/Ns0tXvLI-OI
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Metabolic Flexibility: Switching from Carbs to Fat, and Back Again Mar 03, 2021

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In this episode, I give a bit of a higher level view on metabolic flexibility - what is it? Why is it important? Instances of it? How to improve it? That's all covered in this podcast - enjoy!
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Does Water Fasting increase our Mitochondria? Feb 17, 2021

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In this episode, I briefly cover certain aspects of a study that looks into how effective fasting, specifically multi day water fasting, affects our mitochondrial content in our cells (muscle).
Video Podcast: https://youtu.be/KMU1OcGjjLw
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I ran an Experiment on Myself [Muscle Maintenance] and Your Questions Answered Feb 10, 2021

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In this episode, I cover more detail on an experiment I decided to try on myself over the last 10 months wherein I try to maintain my muscle with minimal effort. I answer questions from 10 people who wrote questions out on how I pulled it off, as well as other questions related to fat loss and muscle perseveration.
Video being Discussed [I Ran an Experiment on Myself]: https://youtu.be/qtim_tXkVoQ
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Mutations that affect Muscle Fusion Feb 03, 2021

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In this podcast, we'll be going over a presentation I gave in one of my courses on Muscle Biology - specifically, how certain mutations in a gene can impede muscle cells' ability to fuse, and on top of that, why some people survive it and why others do not.
Study: https://www.nature.com/articles/ncomms16077
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You Can't Have it All [Lifespan vs Health span] Jan 27, 2021

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There is no human condition wherein you will be at peak form in multiple areas. Much like the idea of the generalist vs the specialist - your body can't be a specialist in all ways, and in the same vein, there is no diet that will be the "ultimate" diet that will help you achieve peak-ness in all areas. The discussion of lifespan vs health span is a great example of that, as well as the idea of growth and uncontrolled growth (cancer).
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