Medical Disruptor™ by Dr. E

Latest Episodes:

You Were Told to Manage Your Diabetes. What If You Could Actually Reverse It? ft Dr. William Hsu Mar 24, 2026

Show notes

You've been told your A1C is "a little high." Maybe your doctor said "watch your diet" and sent you home. Maybe you've been on medication for years and nothing is actually getting better. If that sounds familiar, this episode is going to change how you think about your health.

In this episode of Medical Disruptor, Dr. William Hsu explains why type 2 diabetes is fundamentally a disease of cellular aging and why that changes everything about how we should treat it. He breaks down the Nobel Prize-winning science of cellular autophagy, what actually happens inside your body during a prolonged fast, and why your cells are already programmed to repair and regenerate when given the right conditions.

He also introduces the Fasting Mimicking Diet, a clinically validated five-day nutritional protocol backed by 48 human clinical trials, that activates your body's built-in repair system without requiring a complete lifestyle overhaul.

This is not another conversation about eating less and moving more. This is about giving your body what it needs to actually heal.

What you will learn:

-Why insulin resistance starts 10 to 20 years before your blood sugar looks abnormal

-What diabetes remission actually means and why most patients are never told it is possible

-How 15 days per year of this protocol reduced biological age by a median of 2.5 years in clinical trials

-The one lab marker most doctors skip that could change your entire health picture

Your body has the ability to heal. Most patients are never told that. This episode changes that.

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Chapters

00:00 Why a Harvard Endocrinologist Left Academic Medicine

02:00 What Medicine Gets Wrong About Diabetes

07:00 Why Diabetes Is an Age-Related Disease

13:30 The Nobel Prize Science Behind Your Body's Repair System

19:30 What Is the Fasting Mimicking Diet

25:00 The Clinical Evidence: 48 Trials and Counting

31:00 Pre-Diabetes and False Reassurance: The "Touch of Sugar" Problem

36:00 Why Lifestyle Is One Line and Drugs Are Ten Pages

44:00 Where to Find Dr. Hsu and How to Get Started

Guest Links:

FB: ⁠https://www.facebook.com/prolonfmd/ ⁠

Website: ⁠https://l-nutra.com/

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Where Disease Begins: How Our Environment Affects Our Health Mar 14, 2026

Show notes

Did you know that the air you breathe, the water you drink, and even the food you eat can all affect your health? Believe it or not, your environment can be responsible for up to 70% of your risk for certain illnesses. But how exactly does our environment affect our health? This is a show broadcasted live by Dr. Efrat Lamandre every week with the express purpose of providing free, factual, and practical functional medicine tips to help people prevent disease naturally. Through giving healthy nutrition tips, tips on intermittent fasting, managing stress through diet, and advocating self imrpovement for her patients, Doctor E hopes to help you take control of your health.

Check us out on social media:

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https://www.facebook.com/drefratlamandre

https://www.tiktok.com/@drefratlamandre

#functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting

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What Happens to Your Kidneys When You Eat Too Much Protein ft. Dr. Robin Rose Mar 10, 2026

Show notes

Could your high-protein diet be silently damaging your kidneys?

Kidney decline doesn't announce itself, in fact it builds quietly while you have no idea it’s happening.

Dr. Robin Rose is a physician who found out the hard way. After kidney cancer and losing a kidney, she was told she'd be fine.

She wasn't.

Her GFR dropped to 30. Conventional medicine said monitor and wait. She stopped waiting.

In this episode we talk about:

- Why GFR alone misses early kidney damage

- What the kidney tubules reveal before standard labs catch it

- How too much protein stresses kidneys under pressure

- Why fatigue, brain fog, poor sleep and anxiety may be early warning signs

- What kidney-protective eating actually looks like

- Why toxic burden quietly pushes things in the wrong direction

Dr. Rose went from a GFR of 30 to 68 with one kidney because she stopped waiting for the system to catch up. Your kidneys are already talking.

The question is whether you'll hear them before it 's too late.

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Chapters

[00:00:00] Robin’s unconventional path

[00:05:45] Kidney cancer wake-up

[00:08:40] Why GFR misses early damage

[00:17:53] Kidney-saving lifestyle shifts

[00:35:30] Peptides and kidney repair

Guest Links:

Website: renologyiskidneysuccess.com

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Age Is Just A Number: Taking Control of Having Quality of Life Mar 07, 2026

Show notes

Ever wished you could turn back the clock so to feel great again? Are those birthdays starting to feel like a countdown? Relax, there’s no need to stress! You may not be able to turn back time, but you can rewrite your biology and redefine your health. Imagine being 50 and feeling even better than when you were 30. It's all about taking control of your health, making some lifestyle changes, and getting back that amazing feeling, no matter how old you are. Your age in years? It's just a number - that’s your chronological age. What truly matters is arriving at your best biological age where everyday is a new chance to live life to the fullest! The Knew Method Live is a show broadcasted live by Dr. Efrat Lamandre every week with the express purpose of providing free, factual, and practical functional medicine tips to help people prevent disease naturally. Through giving healthy nutrition tips, tips on intermittent fasting, managing stress through diet, and advocating self improvement for her patients, Doctor E hopes to help you take control of your health. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting

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Your Child's ADHD Might Actually Be Brain Inflammation from Toxic Mold Mar 03, 2026

Show notes

If you're parenting a kid who seems to be changing in real time, more anxious, more reactive, more rigid, more overwhelmed, and you keep getting the same tired answers, this episode is for you. Too often pediatrics treats behavior like the whole story: label it, medicate it, manage it… and then wonder why nothing truly shifts.

In part two of this conversation on Medical Disruptors, I bring back pediatrician and integrative medicine fellow Dr. Pejman Katiraei to go deeper on a missed driver: brain inflammation.

Because "ADHD," anxiety, sensory overload, phobias, obsessive looping, and even rage can be what it looks like when a child's nervous system is stuck in high alert. Not a kid being "difficult."

Pejman explains the brain's immune cells (microglia) in plain English and why, when they're activated, everything can start to feel like a threat. That's when you see fear-based behavior, rigidity, big reactions, and changes that don't match your child's baseline.

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Guest Links:

IG: ⁠https://www.instagram.com/wholistickids/⁠

Website:https://⁠wholistickids.com/people/dr-pejman-katiraei/

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Brain Decline Starts 20 Years Before Alzheimer's and Most Doctors Are Not Looking For It Feb 24, 2026

Show notes

Neurology is amazing in a crisis. Stroke at 3 a.m.? Seizure in the ER? Modern medicine delivers.

But chronic brain issues are different. Migraine. Brain fog. Parkinson’s. Alzheimer’s risk. These often turn into symptom management with a fancy label and a longer medication list.

In this episode of Medical Disruptors, I sit down with neurologist Dr. Ken Sharlin to talk about what comes before the diagnosis gets permanent. Why decline isn’t inevitable. And why the real leverage points aren’t “more meds” or “more supplements”—it’s the inputs that shape inflammation, metabolism, and nervous system stability.

Dr. Sharlin breaks down his 5-part clinical roadmap for brain health, explains why getting the diagnosis right actually matters, and walks through the early drivers that can show up years before symptoms become irreversible.

We also go deep on migraines—what they really are, why your brain can get stuck on high alert, and how you bring the system back under control.

If you want brain health guidance that’s grounded, practical, and not fear-based, hit play.

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Chapters:

[00:00:00] Sharlin’s path

[00:06:10] Acute vs chronic

[00:10:20] Five pillars roadmap

[00:22:40] Alzheimer’s early drivers

[00:34:20] Migraine threat circuitry

Guest Links:

FB: ⁠https://www.facebook.com/SharlinHealthandNeurology⁠

IG: ⁠https://www.instagram.com/sharlinhealthandneurology/⁠

YT: ⁠https://www.youtube.com/@dr.kensharlin1548⁠

Website:⁠https://functionalmedicine.doctor

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What is Hormonal Imbalance and How Does It Impact Health? Feb 21, 2026

Show notes

Does your mood and energy swing up and down? Do you crave sugar or salt? Do you have trouble sleeping? Are you less interested in sex? This could mean your hormones are not in balance. So many things we accept as normal might actually be signs of imbalance.

We often link hormone problems to sex hormones like estrogen, progesterone, and testosterone. However, the reality runs deeper.

When our hormones are not balanced, it can cause all sorts of problems, from mood swings to unexplained weight gain, and constantly feeling tired. But don’t worry Dr. E has your back, she has the answers to how you can start to balance your hormones and get back to feeling your best.

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Why Most Depression Treatments Fail and What to Do Instead Feb 17, 2026

Show notes

You've tried the medications. You've done the therapy. You still don't feel like yourself, and nobody has a real answer for why.

In this episode, I sit down with board-certified psychiatrist Dr. Aruna Nammi, who has spent her career asking the question conventional psychiatry refuses to take seriously: what if the treatment is the problem?

Dr. Nammi breaks down what she calls Psychiatry 2.0, a root-cause approach to depression and anxiety that starts where conventional psychiatry refuses to look.

She walks through the six-month protocol that gets her patients 90% better, what you can start doing right now without a prescription, and why "noncompliant" is what doctors call patients who trust their own bodies over a broken system.

Your body has been telling you something is wrong. This episode is for everyone who has been waiting for someone to finally listen.

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Chapters

[00:00:00] Why psychiatry shifts

[00:03:00] Omega-3 and psychosis

[00:07:30] Medical causes missed

[00:16:55] Psychiatry 2.0 framework

[00:55:00] What to do now

Guest Links:

FB: https://www.facebook.com/trinergyhealth/

IG: https://www.instagram.com/trinergyhealth

YT: https://www.youtube.com/@trinergyhealth6998

Website: https://psychiatry2.com/

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The Real Culprit Behind Heart Disease Feb 14, 2026

Show notes

Heart Disease is the number one killer in America AND... It’s NOT because of cholesterol The truth is that Heart Disease is caused by CHRONIC INFLAMMATION. It’s not as simple as taking cholesterol meds, its so much more! Dr. E will explain the surprising truth behind heart disease. This is a show broadcasted live by Dr. Efrat Lamandre every week with the express purpose of providing free, factual, and practical functional medicine tips to help people prevent disease naturally. Through giving healthy nutrition tips, tips on intermittent fasting, managing stress through diet, and advocating self imrpovement for her patients, Doctor E hopes to help you take control of your health.

Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting 00:00 Introduction 01:14 Debunking The Myth About Heart Disease 07:55 The Inflammation Connection 12:12 WHAT SHOULD I DO? 16:52 Recap

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How Mouth Breathing Is Ruining Your Teeth, Your Sleep, and Even Your Face Shape Feb 11, 2026

Show notes

You breathe through your mouth at night and think nothing of it. Maybe you snore. Maybe your kid does. Your dentist never mentioned it. Your doctor said it was normal.

In this episode of Medical Disruptors, I sit down with Dr. Norma Cortez, a biological airway dentist who starts where most dentistry stops: breathing.

We get into why cavities are often preventable, why "I avoid sugar" isn't the full shield people think it is, and how mouth breathing can quietly shift the oral microbiome, change your face shape, and compromise your sleep without a single provider flagging it.

Dr. Cortez breaks down why the tongue matters more than most people realize, how craniofacial growth shapes the airway, and why myofunctional therapy can change the trajectory early, before kids grow into bigger, harder-to-fix problems.

This episode connects the dots between your mouth, your inflammation, and the answers no one thought to look for.

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Chapters

[00:00:46] Snoring changes everything

[00:06:42] Cavities are preventable

[00:12:21] Tongue and airway

[00:27:56] Root canals debate