Most skincare is designed to improve how aging looks. But can it change what is happening inside the skin itself?
In this conversation, I sit down with Carolina Reis Oliveira, PhD, co-founder and CEO of OneSkin, to explore what actually drives skin aging at the cellular level. Carolina explains how senescent “zombie” cells, UV exposure, inflammation, hormonal changes and a weakened skin barrier affect how skin functions, not just how it looks.
Get OneSkin's new Rich Cream and the rest of the OS-01 line at:
oneskin.co/KAYLA with code KAYLA.
We break down the benefits and limitations of retinol, why chronic redness and flaking are not signs that a product is working better, and whether popular ingredients such as NAD+ precursors, methylene blue and GHK-Cu can penetrate the skin and remain stable. We also discuss collagen supplementation, red light therapy, hyperbaric oxygen, sauna, exercise, sun exposure and the relationship between skin-barrier health and systemic inflammation.
Carolina also shares the science behind OneSkin's OS-01 peptide and its new Face Rich Cream, including findings related to collagen, hyaluronic acid, elastin, filaggrin, hydration, firmness and fine lines.
In this conversation:
-Why many anti-aging products target visible symptoms rather than the biology of skin aging
-How senescent “zombie” cells contribute to inflammation and tissue decline
-How to use retinol without chronically damaging the skin barrier
-Why ingredient penetration, stability and formulation matter
-How skin-barrier dysfunction may affect inflammation throughout the body
-What collagen, red light, hyperbaric oxygen, sauna and exercise can do for the ski
- What OneSkin found when testing GHK-Cu copper peptides
-Why moisturizer alone may not solve age-related dryness
-How OS-01 is designed to target the underlying biology of skin aging
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/female-longevity-community
Optimize your sleep with the Eight Sleep Pod.
Get up to $350 off at https://www.eightsleep.com/Kayla with code “KAYLA”
Support lean muscle and recovery with PerfectAmino essential amino acids: https://bodyhealth.com/products/perfectamino“Kayla20”
Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Connect with Carolina Reis Oliveira:
Instagram: https://www.instagram.com/carolina.reis.phd/
LinkedIn: https://www.linkedin.com/in/carolina-reis-oliveira-a69b8a27/
X: https://x.com/Carol_roliveira
Learn more about OneSkin:
Shop OneSkin: https://oneskin.pxf.io/LKgxy0
Website: https://www.oneskin.co/
Instagram: https://www.instagram.com/oneskin.co/
LinkedIn: https://www.linkedin.com/company/oneskin/
Scientific publications: https://www.oneskin.co/pages/scientific-publications
#SkinLongevity #SkinHealth #HealthyAging #OneSkin #Retinol #SenescentCells #FemaleLongevity #KaylaBarnes