Journal of Clinical Oncology (JCO) Podcast

Latest Episodes:

Are Partners of Patients HPV-Positive Oropharyngeal Cancer at Increased Risk of Infection and Cancer? Apr 28, 2014

Show notes

This partner study suggests that spouses of people with HPV-positive oropharyngeal cancer do not have elevated oral HPV prevalence and the partners' risk for oropharyngeal cancer remains low.

Planning to Survive: The Role of Physicians Apr 21, 2014

Show notes

This JCO podcast provides observations and commentary on the JCO article, "Provision and discussion of survivorship care plans with cancer survivors: Results of a nationally representative survey of oncologists and primary care physicians" by Danielle Blanch-Hartigan, et al.

Minimal Residual Disease (MRD) Study to Optimize Definition and Therapy of High-Risk Acute Lymphoblastic Leukemia Apr 21, 2014

Show notes

The study provides evidence that several patients with high-risk ALL who show a favorable MRD response to chemotherapy can achieve a cure without stem cell transplantation.

Risk-Reducing Oophorectomy in Women with BRCA1 and BRCA2 Mutations: An Opportunity to Personalize Recommendations for Cancer Prevention Mar 31, 2014

Show notes

This podcast summarizes and provides clinical conclusions of a large international study on ovarian cancer incidence and outcomes in women with BRCA1 and BRCA2 mutations.

Anti-EGFR Monoclonal Antibodies in the First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The PEAK Experience Mar 31, 2014

Show notes

In this podcast, I will discuss first-line usage of anti-EGFR therapies in metastatic colorectal cancer in the context of the PEAK trial findings with a focus on the emerging data surrounding RAS oncogene mutations in treatment selection.

Accuracy of BRCAPRO in Women with Ovarian Cancer Mar 17, 2014

Show notes

This JCO podcast provides commentary on the accompanying JCO article "Underestimation of risk of a BRCA1 or BRCA2 mutation in women with high grade serious ovarian cancer by BRCAPRO: A multi-institution study" by Molly S Daniels, et al, and evaluates the need for BRCAPRO in patients with ovarian cancer and the benefit of identifying germline BRCA and other mutations in this population.

Serious Bevacizumab-Associated Gastrointestinal Toxicity Mar 17, 2014

Show notes

This podcast discusses the results of an analysis of the risk of severe gastrointestinal toxicity associated with the administration of bevacizumab to women with advanced ovarian cancer.

The Efficacy of Bevacizumab Combined with Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer Patients and Its Effects On Patient-Reported Outcomes Mar 17, 2014

Show notes

Observations from the AURELIA trial evaluating bevacizumab combined with chemotherapy in platinum resistant recurrent ovarian cancer patients and results from Patient-Reported Outcomes.

Nivolumab: Promising Survival Signal Coupled with Limited Toxicity Raises Expectations Mar 03, 2014

Show notes

This JCO podcast provides observations and commentary on the JCO article, Survival, Durable Tumor Remission, and Long-Term Safety in Patients with Advanced Melanoma Receiving Nivolumab," by Suzanne Topalian, et al.

Decision Shared or Otherwise-: The Ongoing Evolution of Local Therapy for Breast Cancer Feb 18, 2014

Show notes

Coincident with increased reconstruction with mastectomy are higher rates of mastectomy for early stage cancer and contralateral prophylaxis, suggesting the need for assessment of decision support tools and understanding of the patient perspective.