Immune

Latest Episodes:

Immune 86: Where did the SARS-CoV-2 antibodies go? Nov 26, 2024

Show notes

Immune explains how distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense, and failure to establish durable SARS-CoV-2-specific plasma cells in the bone marrow long-lived compartment after mRNA vaccination.

Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
Nasal mucsosal macrophages, neuronal maintenance, and pathogen defense (Mucos Immunol)
No long lived memory B cells after SARS-CoV-2 mRNA vaccination (Nat Comm)
Time stamps by Jolene. Thanks!

Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Immune 85: Immune trade-offs Oct 29, 2024

Show notes

Immune explores the immunological diversity in the upper airway, including memory B and T cells and germinal center B cells, and how chronic infection with Plasmodium parasites leads to development of B cell cancers.

Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
Immune memory diversity in human upper airway (Nature)
How Plasmodium infection promotes B cell cancers (Cell)
Time stamps by Jolene. Thanks!

Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Immune 84: Gender-affirming therapy and immune responses with Petter Brodin Sep 24, 2024

Show notes

Petter Brodin joins Immune to discuss immune system adaptation in individuals assigned female sex at birth and undergoing gender affirming testosterone therapy (trans-men).

Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker

Guest: Petter Brodin

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Links for this episode

MicrobeTV Discord Server
Petter Brodin on TWiV 568
Gender-affirming testosterone treatment (Nature)
Time stamps by Jolene. Thanks!

Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Immune Booster #9: Autoimmune diseases with Mark Shlomchik Sep 10, 2024

Show notes

From the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Mark Shlomchik to talk about his career and the research of his laboratory on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis.

Hosts: Cindy Leifer and Steph Langel

Guest: Mark Shlomchik

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Content in this podcast should not be construed as medical advice.

Immune Booster #8: Immunology, metabolism, and exercise physiology with Heather Caslin Sep 03, 2024

Show notes

From the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Heather Caslin to talk about her training and the research of her laboratory on how diet and exercise affect innate immune cells in health and disease.

Hosts: Cindy Leifer and Brianne Barker

Guest: Heather Caslin

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Content in this podcast should not be construed as medical advice.

Immune 83: Immune cells eating other cells Aug 27, 2024

Show notes

Immune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness.

Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
Microglia shape cortical development and behavior (Cell)
Neutrophil trapping by mast cells (Cell)
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Immune Booster #7: Emerging viruses with David Martinez Aug 20, 2024

Show notes

From the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with David Martinez to talk about his career, the research of his laboratory on viral pathogens of global health importance, and his advice to be persistent and enjoy the journey.

Hosts: Cindy Leifer and Steph Langel

Guest: David Martinez

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Content in this podcast should not be construed as medical advice.

Immune Booster #6: From Ghana to heat shock with Robert Binder Aug 13, 2024

Show notes

From the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Robert Binder to talk about his career, the research of his laboratory on the role of heat shock proteins in cancer immunosurveillance, and the importance of inspiring students as early as possible to think about science.

Hosts: Cindy Leifer and Brianne Barker

Guest: Robert Binder

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Content in this podcast should not be construed as medical advice.

Immune Booster #5: Infections and the gut microbiome with Rafael Polidoro Aug 06, 2024

Show notes

From the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Rafael Polidoro to talk about his career, the research of his laboratory on how the gut microbiome modulates the local and systemic immune responses during infections.

Hosts: Cindy Leifer and Steph Langel

Guest: Rafael Polidoro

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Content in this podcast should not be construed as medical advice.

Immune 82: Bat antibodies are hot Jul 30, 2024

Show notes

Immune reviews the local and systemic responses after human SARS-CoV-2 challenge infection, and how bat antibodies display elevated antigen binding strength and diversity at higher temperatures that are characteristic of flight.

Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!

Links for this episode