Immune

Latest Episodes:

Immune 4: Putting the immunotherapy CAR T before the cancer Jan 23, 2018

Show notes

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Synthetic Immunoreceptors for Cancer Therapy (Trend Mol Med)
Engineering immune cells to treat cancer (Cell)
Engineering T cells for fungal infections (PNAS)
CAR T cells for AIDS (PLoS Path)
CAR T cells (NIH)
Image credit
Letters read on Immune #4

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Cindy - What's In A Name? Steph - Novel Targets Vincent - Friendly Penguin

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to immune@microbe.tv

Immune 3: Two epitopes, four serotypes, and a partridge in a pear tree Dec 16, 2017

Show notes

Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody against Zika virus.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Links for this episode

Model for dengue ADE (Scitable)
Dengue ADE in humans (Science)
Dengvaxia discussion (TWiV 471)
Bi-specific antibody to Zika virus (Cell)
Building Zika Virus
Letters read on Immune #3

Weekly Science Picks

Cindy - Questions answered about starving polar bear video Steph - Deep Work by Cal Newport and Grad Student Tax Vincent - Making art with Excel

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to immune@microbe.tv

Immune 2: Lymphocytes after dark Nov 25, 2017

Show notes

Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph are circadian - it is dependent on the time of day.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Circadian clocks control lymphocyte trafficking (Immunity)
Lymph node image credit
Letters read on Immune #2

Weekly Science Picks

Cindy - Men ask more questions than women at a scientific conference (PLoS One) Steph - House just voted to bankrupt graduate students Vincent - Trump's Legacy: Damaged Brains

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to immune@microbe.tv

Immune 1: Some like it hot Oct 31, 2017

Show notes

Cindy, Steph, and Vincent launch a new podcast, Immune, and reveal how warm temperature protects against atherosclerosis by regulating monocyte migration into the blood.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Links for this episode