Healthcare Unfiltered

Latest Episodes:

Episode 78: CRISPR: The Healthcare Technology of the Future Apr 12, 2022

Show notes

Samarth Kulkarni, PhD, CEO of CRISPR Therapeutics, joins the show to chronicle his journey to CRISPR Therapeutics and to break down the ins-and-outs of the technology. He begins by sharing the evolution of CRISPR as a “molecular barcode” and its first viable indication; how he “bets” the technology will have a major footprint in the cancer, diabetes, and cardiovascular disease treatment landscape; shares strategies for shortening the potential time to market for some of the therapies; explains how AI is used in his line of work; and a variety of other topics.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 77: RCTs Under the Microscope with Vincent Rajkumar Apr 05, 2022

Show notes

Recurring guest Vincent Rajkumar (@VincentRK), MD, Mayo Clinic, provides his input on the complexities of randomized controlled trials. The conversation covers the ability of fellowship programs to train fellows in the nuances of clinical trials, how funding is divvied up for different kinds of trials, how trial design is often influenced by expected time for the new drug to get to the market, when the risk is worth taking with the accelerated approval pathway, how to reconcile study designs when studies with similar control arms are published throughout the world, and a whole lot more.Read Dr. Rajkumar’s spotlight piece in The Lancet.https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)61801-1/fulltextCheck out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 76: Leadership and Entrepreneurship with Samer Saab Mar 29, 2022

Show notes

Chadi shifts gears this week to sit down with a renowned business leader: Samer Saab, founder and CEO of the experience management solution company Explorance. Samer sheds light on the challenges of starting and running a successful business, especially during a once-in-a-century pandemic, and the services Explorance offers. The Great Resignation, surveys given to healthcare workers, burnout, immigrant struggles, transparency and flexibility with employees, balancing personal lives with business lives as the leader of a company, lessons in leadership, business values, and a whole host of other topics are covered in this wide-ranging and inspiring interview.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 75: Updates on GU Cancer Advancements with Rana McKay Mar 22, 2022

Show notes

Rana McKay (@DrRanaMcKay), MD, genitourinary oncologist at UC San Diego, joins the show to recap the clinically relevant research presented at the ASCO GU meeting. She begins with a breakdown of the ARASENS, PROpel, and MAGNITUDE trials for prostate cancer; moves to TROPHY-U-01, EV-103, and ATLANTIS trials for urothelial cancer; hits on KEYNOTE-564 for kidney cancer; and names a few other studies along the way that could move the needle in genitourinary cancers in the near future. *Plus – a surprise guest joins the show unannounced. You’ll have to listen to find out who it is!Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 74: The Ketogenic Saga Continues with Nicholas Norwitz and David Feldman Mar 15, 2022

Show notes

Continuing the ketogenic discussion, Chadi hosts Nick Norwitz (@nicknorwitz), PhD, Harvard Medical School, and welcomes back Dave Feldman (@DaveKeto), senior software engineer and entrepreneur, to discuss their recently authored paper “Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a ‘Lean Mass Hyper-Responder’ Phenotype.” The trio discuss the inspiration for the paper, the methodology and survey questions, results and take-home messages, and the broad range of reactions the paper evoked.Read the authors’ discussed research paper.https://academic.oup.com/cdn/article/6/1/nzab144/6446805Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 73: The Enigma of the Pathology Profession with Sanam Loghavi Mar 08, 2022

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Sanam Loghavi (@sanamloghavi), MD, hematopathologist and molecular pathologist at the University of Texas MD Anderson Center, provides a clear picture of pathology as a specialty in this informative episode. Dr. Loghavi argues that medical school curriculum falls short in including pathology as a legitimate specialty for students to pursue, credits and discredits the preconceived notions about what pathology is all about, shares what differentiates good pathologists and exceptional pathologists, breaks down the subspecialties within pathology, comments on the future of artificial intelligence in pathology, and a whole lot more.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 72: Paul Offit: Making Sense of All of Your Vaccine Questions Mar 01, 2022

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Chadi hosts a very renowned, high profile guest – one of the leading vaccine experts in the world and the man co-credited with developing the rotavirus vaccine: Paul Offit (@DrPaulOffit), MD, Director of the Vaccine Education Center and Professor of Pediatrics, Children’s Hospital of Philadelphia. Dr. Offit tackles the hard-hitting questions on everyone’s minds: whether public health policy decisions should be made based on randomized controlled trials during a pandemic, what went into the FDA’s decision to postpone vaccine approval for young children, whether vaccine mandates are moral and justifiable for children, what is the basis behind a third booster dose for adults, and a whole lot more.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 71: Vaccine Hesitancy and Cognitive Bias with Tara Haelle Feb 22, 2022

Show notes

Tara Haella (@tarahaelle), independent science/health journalist, joins the show to discuss her reporting on vaccine hesitancy long before the pandemic (the “trenches of the mommy wars”), how this previous work aligns with today’s COVID vaccine hesitancy, and how cognitive bias plays a substantial part in our individual feelings toward vaccines. Tara explains the longstanding history of vaccine hesitancy, how she came to initially distrust the CDC, how vaccine hesitancy was likely exacerbated by political motives when COVID hit, how much blame public health messaging may have toward COVID vaccine hesitancy, and a host of other interesting, controversial topics.View Tara’s personal website.https://tarahaelle.net/Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 70: Walking America and the World with Chris Arnade Feb 15, 2022

Show notes

Chris Arnade (@Chris_arnade), long-time writer and author of “Dignity: Seeking Respect in Back Row America,” joins the show to discuss his recent experience walking America and how his views on politics and the COVID-19 response have changed as a result. Chris shares his unique upbringing and professional background, ways in which he satisfied his early interest in long walks and what he made of these walks, and how this interest developed into touring the U.S. and photographing the people he encountered. Chadi and Chris discuss the “real America” and break down the “rows” of people in the country, how leaders have failed the lower class when it comes to COVID messaging, and many other interesting topics.Check out “Dignity: Seeking Respect in Back Row America.”https://www.amazon.com/Dignity-Seeking-Respect-Back-America/dp/0525534733Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 69: Baz: The Journey of a True Healer Feb 08, 2022

Show notes

Chadi hosts a truly inspiring pediatrician, author, philanthropist, humanitarian, and self-described “healer”: Noha Baz. Dr. Baz opens up about her unique childhood beginning in France and moving to Lebanon, some harrowing stories about young patients being refused care because of lack of money to pay for treatment, her eventual founding of “Les Petits Soleils” in 1997 to provide medical care for children living in Lebanon not benefiting from health coverage, maintaining her focus despite political turmoil in Lebanon, her deep love for food and how she incorporates it into her work, and a whole lot more.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

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