Good Medicine On The Go

Latest Episodes:

Conversations with Clinicians; Answers to Anorexia with Dr. James Greenblatt, MD Oct 26, 2021

Show notes

It’s time to fundamentally change our treatment model for anorexia nervosa. Check out Dr. Greenblatt, MD's new book, Answers to Anorexia at

https://www.jamesgreenblattmd.com/answers-to-anorexia/

The recovery, relapse, and mortality rates for anorexia are simply staggering. We can’t afford to wait.

Roughly 3 million people in the US over 15 years old have anorexia.
The death rate of anorexia nervosa is 12x higher than the annual death rate from all other causes combined for young women between ages 15-24 years.
Over the last decade, treatment centers are reporting an admission increase of 400% among women over 40yrs.
Traditional psychotherapy is associated with a relapse rate of 50% and a fatality rate higher than any other mental health disorder.

Nutrigenomics and the Big Picture #11 Oct 08, 2021

Show notes

Nutrigenomic testing allows practitioners to identify their patients’ unique genetic differences. These differences can impact nutrient requirements, susceptibility to environmental factors, or predispositions to chronic conditions. Combining nutrigenomic testing with organic acids testing (OAT) provides practitioners with key biomarkers that can be matched to certain genes and allow for the development of personalized nutrition and lifestyle advice. Join us on Monday, October 11th from 6:30-7:15 EST pm when Dr. Denise Furness unpacks a 32-year old female with consistently high B12serum levels, chronic fatigue, and fluctuating thyroid levels case study. Dr. Furness lends her expertise to this infertility, preconception, topic and takes your questions.

Dr. Denise Furness will be using a PureGenomics® and a Great Plains Laboratories® OATS test.

PureGenomics® was developed by Pure Encapsulations to harness the science of nutrigenomics to empower individuals to uncover the relationship between their genes, nutrition, and wellness.

Nutrigenomics and the Big Picture #10 Sep 09, 2021

Show notes

A 35-year old woman, grew up in a rural Pennsylvania farming community. 4 neighborhoods in total and acres and acres of rural farmland. The water source is owned by a private company; the owner is a local farmer. Evidently, the water has been leaking up to 70%. Breast cancer, celiac, asthma are on the rise in the community. One girl died of an asthma attack.

Symptoms

She feels misdiagnosed as a young girl. She feels they are POTS attacks, not anxiety attacks. She would often faint while working at McDonald's. She also has Ellers Danslos Dx, chronic fatigue, and high levels of Epstein bar virus. She constantly has bruises on her legs, and trouble with tendons and ligaments, as well as being super bendy- she has tight muscles and loose joints. She is constantly in PT. Her sister has mast cell activation and asthma. Otherwise nothing else in her family history. SNPs mentioned in this episode for the top objective of addiction Vitamins/Minerals/Omega 3s Category Vit D: GC, DHCR7, CYP2R1 Cognitive and Mental Health Category COMT met/met AA (Executive Function) TPH2 (Serotonin Production)

BDNF (Brain-Derived Neurotrophic Factor)

Energy and Fitness Category

COL1A1 (Tendon or Ligament Injury)

COL5A1 (Tendon or Ligament Injury)

Detoxification Category

SOD2 (Antioxidant Enzymes)

GSTP1 (Environmental Toxins)

Immune Category

TNF-alpha (TNFalpha activation)

Resources

Do you have a reputable water testing company? Let us know! Have questions about how cannabis fits into your toolbox? Email: kara@karawarecoaching.com

Nutrigenomics and the Big Picture #9 Aug 16, 2021

Show notes

A 29-year old man struggling with addiction. When he was younger, he was diagnosed with ADHD/ADD, struggled with focus, parents didn't want to place the patient on medications and didn't know about addressing root causes manifesting these symptoms. He began using drugs in high school and eventually fell into heroin and Alcohol. SNPs mentioned in this episode for the top objective of addiction Vitamins/Minerals/Omega 3s Category Vit A: BCMO1 genes Omega 3: FADS1 genes Vit D: GC, DHCR7, CYP2R1 Riboflavin and Folate: MTHFR c677T and 1298c Cognitive and Mental Health Category COMT val/val GG (Executive Function) DRD2s (Dopamine Receptors) Metabolic and Weight Management Category FTO (Protein Intake. FTO draws upon the dopaminergic pathway)

Resources

Nutrigenomics Case Study Events
2021 GMOTG Events Line-up
PureGenomics
PureGenomics Trait Tutorials
Schedule a complimentary 1:1 Welcome to PureGenomics coaching session
Have questions about how cannabis fits into your toolbox? Email: kara@karawarecoaching.com

Nutrigenomics and the Big Picture #8 Jul 30, 2021

Show notes

A 55-year-old female who has been living with IBS since her early twenties. She had possible food poisoning around 7-years ago. She is eating a whole foods diet yet still has regular exposure to gluten and dairy. The patient adores running, however, is experiencing frequent injuries.

Patient's top objectives

1. IBS

2. Mood

3. Energy

4. Weight

5.) Recurring Injuries

Vitamins/Minerals/Omega 3s:

· PEMT (rs7946) (Choline)

· BCMO1(rs12934922) (Vit A)

· BCMO1(rs7501331 (Vit A)

· CYP2R1(rs10741657) (Vit D)

· GC(rs2282679) (Vit D)

· DHCR7(rs12785878) (Vit D)

Gastrointestinal Category:

· FUT2 (rs601338) (Microbial Diversity in Small Intestine)

· MCM6(rs4988235 (Lactose Intolerance)

Cognitive and Mental Health Category:

· COMT (rs4680) (Executive Function)

· TPH2 (Serotonin)

Exercise and Fitness Category:

· COL1A1(rs1800012) (Tendon and Ligament Injury)

· COL5A1(rs12722) (Tendon and Ligament Injury)

Resources

Nutrigenomics and the Big Picture #7 Jul 23, 2021

Show notes

A 45-year-old female who is inquiring about bio-identical hormones for depression, anxiety, and weight gain.

Patient's top objectives

1. Hormones

2. Mood

3. Weight

COMT Val/Val (wild type)

COMT met/met (homozygous)

SNPs (genetic variants) mentioned in this minisode:

Vitamins/Minerals/Omega 3s category:

· PEMT (rs7946) (Choline)

Cognitive Health and Memory category:

· COMT (rs4680)

Detoxification category:

· COMT (rs4680) (Estrogen Metabolism)

· GSTP1 (rs1695) (Glutathione Peroxidase)

· SOD2 (rs4880) (Antioxidant Enzymes)

Resources

Nutrigenomics and the Big Picture #6 Jul 16, 2021

Show notes

A 57-year-old male CEO, with problems with memory. Pt has borderline blood pressure. Problems with memory started with taking a statin. Pt also has issues with borderline blood sugar HGA1C is 5.8 and bloating. Loses weight by avoiding fats and carbs

Patient's top objectives:

1. Memory

2. Borderline blood sugar

3. Borderline blood pressure

SNPs (genetic variants) mentioned in this minisode:

Cardiovascular category:

· SLCO1B1(rs4149056)

· ACE (rs4343)

· AGT (rs699)

· CYP1A2 (rs762551)

· LIPC (rs1800588)

· PPARD(rs2016520)

Metabolic Weight-Management category:

· MC4R(rs17782313)

· FTO (rs9939609)

Resources

Nutrigenomics and the Big Picture #5 Jul 10, 2021

Show notes

31-year old male, placed on Ritalin in the second grade, whose top objectives are anxiety and depression, especially in the winter months, food aversions, year-round allergies

SNPs (genetic variants) mentioned in this minisode:

Vit/Min/Omega 3s category:

BCMO1 (rs12934922, rsrs7501331) (Vit A)
GC (rsrs2282679), (Vit D)
CYP2R1(rs10741657) (Vit D)
DHCR7(rs12785878) (Vit D)
FADS1 (rs174537, rs174546, rs174547) (Omega 3s)
MTHFD1 (rs2236225) (Choline)
PEMT (rs7946) (Choline)

Cognitive Health and Memory category:

COMT (rs4680) (Executive Functioning)
ANKK1/ DRD2 (rs1800497) (Dopamine Receptors)
DRD2 (rs2283265) (Dopamine Receptors)
DRD2 (rs1076560) (Dopamine Receptors)

Resources

Nutrigenomics Case Study Events
2021 GMOTG Events Line-up
PureGenomics
PureGenomics Trait Tutorials
Schedule a complimentary 1:1 Welcome to PureGenomics coaching session
Methylation Genetics: Why Choline is Often the Missing Link

Email me for a summary of our Good Medicine On the Go (GMOTG) May case study event! You can read how these events can assist you with the interpretation and application of patients' genetic profiles to steer your clinical decision-making.

Nutrigenomics and the Big Picture #4 Jul 02, 2021

Show notes

A 57-year old female patient, Dx with Hashimotos, has felt/been sick for 12+ years. Hx of mold illness, heavy metal toxicity, extreme fatigue, anxiety, vision problems, difficulty thinking, can’t lose weight.

The patient has a clean DF/GF diet; has done AIP in past. No alcohol, limited caffeine. Eats very clean diet, loads of vegetables and plant matter. Beverages mostly water. Limited red meat. Snacks on nuts.

Top objectives:

“Can’t lose weight” /cellulite
High cholesterol/triglycerides.
AnxietyFatigue
Vision problems
Difficulty thinking

SNPs (genetic variants) mentioned in this minisode:

vit/Min/Omega 3s category:

BCMO1 (rs12934922, rsrs7501331) (Vit A)
GC (rsrs2282679) (Vit D)
CYP2R1(rs10741657) (Vit D)
DHCR7(rs12785878) (Vit D)
FADS1 (rs174537, rs174546, rs174547) (Omega 3s)

Immune Health category:

IL-6 (rs1800795)

Resources:

Email me for a summary of our Good Medicine On the Go (GMOTG) May case study event! You can read how these events can assist you with the interpretation and application of patients' genetic profiles to steer your clinical decision-making.

Nutrigenomics and the Big Picture #3 Jun 25, 2021

Show notes

A35-year old working mom of 3. The patient says “I am young but I feel so old.” It is hard for her to enjoy life and time with her kids when she is always feeling tired, foggy-headed, and achy all over.

Top objectives: