Gladden Longevity Podcast

Latest Episodes:

Molecular Hydrogen to Bring the Body into Balance – an Interview with Tyler LeBaron – Episode 17 May 22, 2018

Show notes

On this episode, Tyler LeBaron of the Molecular Hydrogen Institute (MHI) comes on the show to talk about molecular hydrogen and how it can supplement the body for anti-aging and performance. They discuss some of the promise that drinking hydrogen-rich water is showing for Parkinson's patients and in other brain injury therapies.

They consider how the intake of molecular hydrogen aids in ATP production and mitochondrial function. Free radicals can cause damage to your cells, and molecular hydrogen can act as a signaling molecule to upregulate your body to better manage oxidative stress. Our body needs oxidative power and reductive power in balance, and molecular hydrogen can help bring you back to homeostasis.

Hydrogen also helps modulates the system that causes inflammation, which is a major cause of aging.

LeBaron suggests how and when to get hydrogen into your system and offers some warnings about products on the market.

Dr. Gladden talks about some of the ways he uses molecular hydrogen with his patients at Apex.

They also discuss the benefits of being in a "flow state" in your life, during work or working out.

Special Guest:

Tyler W. LeBaron is the Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Institute. His background is in biochemistry and was a 1-year Adjunct Instructor of Physiology. He Interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas.

Learn more at the Molecular Hydrogen Institute.

Follow LeBaron on Facebook.

NAD and Anti-Aging – an Interview with Thomas Ingoglia – Episode 16 May 08, 2018

Show notes

Thomas Ingoglia joined Mark Young at RAADfest 2017 to talk about NAD (Nicotinamide adenine dinucleotide), a molecule showing great potential for its anti-aging effects, as well as helping people with addiction recovery and chronic health conditions.

Ingoglia discusses the treatments available at the NAD Treatment Center, describing what people wanting to maintain their health would get out of the intravenous infusion of NAD offered. This includes an increase in energy, pain reduction, increased physical performance and more.

He also suggests what a person should do in order to live beyond 120.

Listento the Ben Greenfield Fitness podcast with Ingoglia about NAD.

Learn moreabout the NAD Treatment Center and follow them on Twitter @NADTreatmentand on Facebook.

About the guest:

Thomas Ingoglia is the business director at NAD Treatment Center. He is a private investor with a master's degree in finance. In the midst of trading, investing in technology and developing real estate in Costa Rica, Tom became very sick. He was initially prescribed antibiotics, suffered from an adverse reaction and was told that he'd have stomach problems for the rest of his life. In the years that followed, Tom also developed severe food allergies. His symptoms worsened, and he next began dealing with insomnia, anxiety, muscle pain, tedinopathies, joint pain, chronic fatigue syndrome, altered and clouded cognition and headaches. He finally had a mental breakdown in 2008.

After a prolonged period of taking antibiotics, Tom began experiencing tendonitis throughout his fingers, hands, wrists and ankles and feet, so he started taking pain medications to relieve this pain. He had to give up his career in trading because his sole focus for the next eight years would be on finding a cure to his growing symptoms.

Tom's life consisted of working with physical therapists, going to the gym, going to new doctors, and trying new foods to see if it would help. "I was in the prison of constant pain, and would try anything, any place, that might help."

Throughout Tom's eight-year battle, he was prescribed consistently and persistently more medication. For six years, he was taking excessive amounts of Hydrocodone and Tramadol every day.

Tom became obsessed with researching symptoms and treatments and learned about the NAD+ treatment. He visited a clinic, and on Day 7 of his treatment, "It hit me. I started feeling better. I felt amazing. There was a calm that came over me. I felt safe. I just had no cravings for drugs or pain meds. There was no need for them. I just didn't have the excruciating pain that I had before. I felt eight years of pain melting away.

Tom's pain began to dissipate, and he started getting his energy back. "I was so paranoid of relapses, because they had happened in the past, but over the course of the following months I started feeling better, just as the clinic had predicted. Finally, I got my sanity back."

More than a year later, Tom has nearly fully recovered, from both his illness and his cravings for pain medications. He's immersed himself in better understanding the NAD+ that saved his life, along with related treatments, and has engaged two cofounders to assist him in building out a facility to help bring this treatment to others in similar situations.

Preventing Cardiovascular Disease – an Interview with Dr. Jeffry Life – Episode 15 Apr 24, 2018

Show notes

On this episode, we're featuring a special RAAD Fest discussion from last year between Dr. Gladden and Dr. Jeffry Life, a doctor who has focused his practice on healthy aging and helping patients avoiding heart attacks and strokes. He incorporates the Bale-Doneen Method (learn more in the book Beat the Heart Attack Gene) in his treatment plans, which is about aggressively looking for vascular inflammation that causes heart disease and working to stop it.

They discuss some of the testing that can be done to identify vascular risk factors, which fall outside of the normal insurance-based model of healthcare.

Dr. Life describes what he does for himself to improve his own health, fitness and longevity. He and Dr. Gladden discuss hormone replacement and HGH and when it is appropriate treatment.

Special Guest:

In 1997, Dr. Jeffry Life was a board-certified family practice physician who was 59 years old, overweight, poorly conditioned body and in rapidly declining health. He couldn't tie his shoes without losing his breath. His stomach was huge, his muscles and joints ached, and he was miserable. He decided it was time to focus some much-needed medical attention on himself.

Not knowing where to start, he began reading fitness magazines and came across an article that featured the winners of the Body-for-LIFE contest. He followed a low-glycemic/low-fat diet, took supplements, and plunged into a heavy exercise regimen with help from a former Navy Seal personal trainer, Ernie Baul. At the end of 1998, at 60 years of age and after consistently eating right and training right, he became the GRAND CHAMPION in Bill Phillip's 1998 Body-for-LIFE contest.

He continued his commitment to the Fitness Lifestyle, yet despite my hard work and dedication, he started losing ground as he edged toward 63. He was slowly losing muscle mass, and strength and was regaining body fat. His energy level was waning, as was his libido. He had heard about the Anti-Aging Medicine Movement, so he investigated further. He learned a whole new level of protocols and philosophies and immediately agreed to become a patient.

Within a couple weeks, Life started to see and feel a marked shift in his body, mind and spirit. He was once again becoming a vibrant, healthy and happy man. It was life-altering and became the catalyst that moved him from Family Medicine to healthy aging medicine. He wanted every man and woman that struggled as he had to have hope for a better life. Today, at 78 years of age, he is in the best shape of his life. He's in the gym 5 days a week. He has a thriving practice in Charleston, West Virginia (The Life Center for Healthy Aging), and he has authored three books: The Life Plan, Mastering the Life Plan and The Life Plan Diet.

Learn more at https://www.drlife.com/.

Follow him on Twitter @DrLife, Instagram @drjlife and Facebook.

Treating Cancer Outside of the Traditional Protocols – an Interview with Dr. Thomas Incledon, PhD – Episode 14 Apr 10, 2018

Show notes

On this episode, Dr. Gladden and Mark dive into the subject of cancer, inviting Dr. Thomas Incledon of Causenta® Wellnessto talk about a new model of treating cancer patients outside of traditional medicine.

It's often difficult for doctors within the standard healthcare system to break out of typical thinking about cancer treatments. This often prevents new discoveries from being applied to treatment plans, especially when reimbursement is a priority.

Dr. Incledon discusses some alternative treatments they are using at Causenta, including light-based therapy, ozone therapy, and oxidative stress. They also pay careful attention to the order in which they implement therapies for patients, as well as how the rest of the body plays a role in treatment.

They talk about studying different strategies that challenge the metabolic pathways of cancer and what that means for other health management during treatment. Every person is different, and that must be taken into account when planning out therapy.

Dr. Incledon suggests what things a person should do first when they receive a cancer diagnosis and what to ask their doctor. He also recommends actions we can take to help reduce our risk for cancer, including getting good sleep, getting outside, drinking enough fluid, exercising and eating a variety of colors in your diet.

Ask yourself, "For those dealing with cancer directly or with a loved one, what are you doing outside of mainstream care to supplement treatment?"

About the guest:

Dr. Thomas Incledon, holds a B.S. in Exercise Science, B.S. in Nutrition, M.S. in Kinesiology, and Ph.D. in Exercise Physiology.

Since 1989, Dr. Tom Incledon has been recognized as one of the world's leading experts in the areas of human health and athletic performance. He is the founder and CEO of Causenta Wellness, a cutting-edge wellness and cancer treatment center in Scottsdale, Arizona. Dr. Tom helps individuals from all walks of life to understand the cause of there health issues and move toward optimal health. His clinic helps patients improve their quality of life, and provides transformational results for those seeking to improve their athletic performance.

He belongs to over 30 different scientific organizations and reviews several peer-reviewed journals. Dr. Tom is one of the most sought-after healthcare providers in the United States.

Dr. Tom Incledon's life goal is stated in his own words, "eradicating disease from the face of the Earth." This pursuit has led him to pioneer some of the most revolutionary cancer treatments in the history of medicine. As an example, measuring every gene in a person AND every gene in their cancer cell AND over 1000 cancer biomarkers, then take that data to determine the best strategy to help that person beat cancer. His strategies help patients overcome cancer quickly, painlessly, and dramatically improve their quality of life—placing Causenta at the forefront of cancer treatment.

Known as "The World's Strongest Sports Scientist," he has achieved recognition based on his own experience with health and fitness. His extensive academic understanding of the human body supports his expertise. Dr. Tom set national records in Strongman Competitions. He is best known for completing 19 reps in the 200 lb. Axle Press.

On the supplement and nutrition front, Dr. Incledon is the "go-to" advisor for many of the world's most popular dietary supplement/nutraceutical companies and health magazines. (Including- Men's Health and Muscle & Fitness). More specifically, he excels in creating effective formulations.

Follow Causenta Wellness on Facebookand Instagram.

The Potential of Telomerase for Extending Lifespan with Dr. Bill Andrews – Episode 13 Mar 27, 2018

Show notes

We welcome back Dr. Bill Andrews of Sierra Sciences to further expand on research into telomeres and telomerase for extending lifespan.

Dr. Andrews explains how the existing research shows that there are potential telomere lengtheners, but they are still losing the tug-of-war with telomere shortening. He talks about how lack of funding may be the primary obstacle for telomere breakthroughs.

Dr. Andrews also explains the actual link between telomerase and cancer, which is often misunderstood. They also consider the implications of gene therapy and gene editing in terms of producing telomerase.

The main cause of telomere shortening is a lack of telomerase, though some things accelerate the process, like oxidative stress and inflammation. The doctors list a number of things people can do to reduce oxidative stress, including lifestyle changes and supplements that can help.

Learn more about products by defytime® here.

For information on IsaGenesis®/Product B, visit here.

Learn more about Life Length: https://lifelength.com/

Learn more about RAADfest.

On This Week on Longevity Science, Robb Taylor talks about the potential of Vitamin C to help in cancer therapy. Read more on the blog.

Ask yourself: How serious am I about altering my lifestyle to protect my telomere lengths, and how much of my life, thought process and financial resources should I devote to this?

Special Guest:

Dr. Bill Andrews is the President and CEO of Sierra Sciences. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension, including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey.

Since 1981, Bill Andrews has focused on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as "National Inventor of the Year" in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals.

Bill is also an avid ultra-marathon runner. Born December 10, 1951, he regularly competes in 100k and 100+ mile runs often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High.

You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now.

Follow Sierra Sciences on Facebook and Twitter: @SierraSciences.

Preserving Longevity Through Telomeres - with Special Guest Dr. Bill Andrews - Ep 12 Mar 12, 2018

Show notes

On this episode, we're featuring a special RAAD Fest discussion from last year between Dr. Gladden and Dr. Bill Andrews, one of the leading scientists in telomere research.

Dr. Andrews explains how telomeres work and how the length impacts your life expectancy. Put simply, longer telomeres are always good, and the shortening of them is always associated with disease and cell death.

Dr. Andrews mentions the book, The Telomere Effect by Dr. Elizabeth Blackburn and Dr. Elissa Epel, regarding slowing the shortening of telomeres. They discuss the research into telomerase activators and the hope for working toward lengthening telomeres.

He discusses TAM-818 and TA-65® as means to reduce the rate of telomere shortening and offers up his top three suggestions on what people can do to extend their lives.

Special Guest:

You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now.

Your True Age - Episode 11 Mar 06, 2018

Show notes

On this episode, Mark and Dr. Gladden discuss the many ways your true biological age can be determined, your longevity possibly predicted – and what you can do to improve these factors.

Mark talks about his experience with an ozone therapy machine and Vasper at Dr. Gladden's clinic. Gladden explains the benefits of ozone in the body and how the therapy works, including increasing a molecule called NAD, which allows the cells to make more ATP.

Telomeres are the "timekeepers" for the cell, caps at the ends of your chromosomes.

You can somewhat predict the span of your life by the length of your telomeres, but you can do things to improve telomere lengths. A telomere length can show you're physiologically younger or older than your chronological age. One company that does a thorough test on telomere length is Life Length.

Cell mitochondria make ATP, or energy for cells. Cancer develops in cells that are abnormal and energy-starved. Cancer cells turn on telomerase to re-lengthen their telomeres, possibly making them immortal.

Your lifestyle significantly impacts if you are shortening or lengthening your telomeres.

Exercise, fish oil, meditation, Astragalus (via cycloastragenol, for instance) are tools to preserve the length of your telomeres. Molecular hydrogen can protect against radiation damage to telomeres.

They consider other ways to judge a person's true age, like arterial age, bone age and brain age.

They discuss the mindset that one should develop that places a high value on your health. Many people sacrifice their health in an effort to get more money, but then they spend much of that money trying to recover their health later in life. Mark talks about this in terms of how we experience the life we have, at different ages, and he stresses the importance of making novelty a priority, so our life feels fuller for longer.

Robb Taylor and Dr. Gladden also discuss 5 alternative cancer therapies your doctor might not tell you about. To read a more in-depth article, visit the blog.

Ask yourself, "What can you do to take care of your real asset, your telomeres?"

Gladden Longevity Podcast Disclosures

Production & Independence

The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

Medical Disclaimer

The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

Sponsorships & Affiliate Disclosures

To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

Additional Note on Content Integrity

All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

Improving Sexual Health for Men - Episode 10 Feb 20, 2018

Show notes

On this episode that focuses on men's sexual health, Dr. Gladden, Mark and Robb explore the importance of sexual health on body, mind and longevity. Statistically, people who have more sex live longer, and your ability to perform sexually is a great barometer of the health of your cardiovascular and nervous systems.

They discuss some of chemical responses in the body that occur before, during and after sex, including the release of nitric oxide and oxytocin.

There are many ways we can sabotage our own sex lives, including consuming poor diets, alcohol and other harmful substances. Dr. Gladden talks about how essential nitric oxide is for sexual health and recommends some nitrate-rich foods that can help improve it. Gladden references products, BeetElite® and Neo40®, from https://www.humann.com/, which can be good supplements to increase your dietary nitrates. They discuss how popular erectile dysfunction drugs like Cialis®, Levitra® and Viagra® work and explain that they'll still only be as good as the nitric oxide we already have in our bodies.

Hormones balance is critical not only for sexual health, but for overall health. It's not just about hormones levels the blood but also the metabolites that show up in the urine you expel. Gladden references the DUTCH (dried urine test for comprehensive hormones) test that he uses in his practice to examine hormone levels for patients. When critical hormone levels go down, we lose our ability to handle our environment, perform sexually and end up at risk for cancers and other physiological problems. They consider the different ways testosterone can be delivered as a supplement to aid in libido and sexual health.

Dr. Gladden and Mark briefly talk about peptides, short chains of amino acids that are being experimented with for their health benefits. Melanotan and PT-141 may help improve libido and erectile function; Epithalon may improve orgasmic quality for people.

Sex begins in the mind, so if there are challenges, it's essential to heal the biology as well as the psychology. Mark describes how neuro-associations can lead to difficult-to-break post-traumatic stress responses, and he explains when hypnosis might be able to help you. They consider how pornography can affect a person's ability to perform sexually, on chemical and psychological levels. When it comes to improving your sex life with your partner, continuous communication and engagement is essential for long-term compatibility.

Ask yourself, "What can I do today to move in a direction that optimizes my biology and my psychology for my sexual health?"

How to Exercise for Longevity - Episode 9 Feb 06, 2018

Show notes

First and foremost, it's crucial to envision that you'll still be able to do athletic activities when you're into your 80s, 90s and beyond. Dr. Gladden explains that he's getting older chronologically, but he's getting younger physiologically – and he speaks on his mindset that sets him up for success.

The Doctor recommends getting a cardio pulmonary stress test before starting a new exercise plan, to avoid injury or catastrophic health problems like a heart attack. Another test that helps identify potential physiological problems ahead of time is the MET-TEST.

They discuss different kinds of physical training, including HIIT (high intensity interval training) and the need to develop a cardio baseline by exercising at a slower heartrate over an extended period of time. The recommend spreading out the kind of workouts that you do, to spare yourself from injury and build different muscle groups. Gladden provides some other tips on preventing injury, as well as how to cope and maintain strength if you do get injured. Gladden also talks about Fortetropin®, a myostatin inhibitor that helps people build muscle by decreasing the way muscle is broken down.

They talk about the benefits of "loading your frame" to improve skeletal, tendon and ligament strength, then they discuss balance training and how to incorporate it into your life.

Creating a habit of doing something every day is much better for your body and mind rather than only pushing your body to its limits once or twice a week. Play is also critical when you exercise, for keeping your mind and body youthful.

In This week in Longevity Science, they discuss Klotho, what is being called "the longevity protein," as it could one day play a vital role in helping treat potentially deadly conditions. For more information on the subject, visit https://wisdomtolive.com/longevity-protein-could-save-lives-improve-health/.

Key takeaways:

Before you start an exercise plan, be safe, get tested, and work out smart to prevent injury.
For your mindset, focus on being fast, agile and strong at every age.
Develop the habit of exercise in small, sustaining steps.
Variety in exercise is a necessity.
Keep exercise fun and try new things.

For this week's empowering question, ask yourself, "How would you change your training now if you want to be engaged in your favorite activity years, or even decades, from now?"

What Your Doctor Should Tell You – Episode 8 Jan 23, 2018

Show notes

This week's episode focuses on the difference between what your doctor's visit should sound like versus the few minutes the average doctor spends with a patient. Dr. Gladden explains why these short visits prevail in the current health care system, and they discuss how you need to change your mindset about who is responsible for keeping you healthy.

They talk about the dangers of NSAIDs and a how most people use them. When anti-inflammatory drugs are used regularly, the root cause of the inflammation is often not addressed and is allowed to continue to cause damage. They discuss inflammation and how it leads to aging.

This Week in Longevity Science also focuses on the average time a doctor spends with patients, questioning how much your healthcare provider can actually address your well-being in that short time. Dr. Gladden recommends how to get more out of your visits.

For a unique perspective, Dr. Gladden goes through real results from some of Mark's own tests after a recent visit – showing step by step how this critical set of data can be used to extend Mark's lifespan.

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