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    Health & Fitness

    Gladden Longevity Podcast

    On this podcast focused on health and human longevity, Dr. Jeffrey R. Gladden, MD, FACC, examine the latest scientific research, technology, and biohacks to uncover the truth about the human body’s potential for extending both life and health span well past what most people accept as biological facts.

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    Latest Episodes:
    Making Resolutions You Can Keep – Episode 7 Jan 09, 2018
    Show notes

    As 2018 begins, there are things to keep in mind as you set goals for improving health and happiness. New Year's resolutions need to be measurable and have a timetable. Also, we need to create good habits to be able to achieve these goals. Fostering small, good habits set you up for greatness and also give you faster feedback on how well you're doing.

    As people dive into new diets at the start of the year, Dr. Gladden and Mark talk about how no diet is a perfect fit for everyone. You need to pay attention to your own genetic make-up or possibly put yourself at risk.

    This week in longevity science, Robb talks about gene editing and its possibilities for erasing genetic medical conditions. For more information on CRISPR, visit https://www.wired.com/story/what-is-crispr-gene-editing/ and https://gizmodo.com/in-2018-we-will-crispr-human-beings-1821540150.

    Ask yourself: how can I change my mindset to one that opens up my longevity and human performance in 2018?


    Immunity and Aging – An Interview with Dr. Gregory Fahy – Episode 6 Dec 19, 2017
    Show notes

    Dr. Gregory Fahy is a cryobiologist and biogerontologist. He's credited with a many of the breakthroughs in cryopreservation, and he has been working on finding new ways to use already-approved drugs.

    Fahy talks about his work with human growth hormone (HGH) and shares the highlights of the results of his first human trials with it. He talks about what happens around age 62-65 for most people that rapidly increases chances of death.

    Fahy urges people interested in longevity to pay attention to what is on the cutting edge of medicine, he stresses the importance of nicotinamide adenine dinucleotide (NAD) in staying youthful, and he believes there is a profound connection between the immune system and aging.

    Also on the podcast, Mark explains what he means when he says Americans are eating like we're on death row.

    Dr. Gladden expands on HGH and considers some of the drawbacks and complications that could occur when it is used as treatment.

    In This Week in Longevity Science, they discuss peptides as a form of treatment, including how they function in the body and their promising regenerative properties. Research is being done to see how well peptides could work for highly customized medicine, not only for a specific disease but the exact disease within the individual.

    Ask yourself, "How am I going to learn more about this cutting-edge science in order to change the trajectory of my aging?"

    About the Guest:

    Gregory M. Fahy, Ph.D.

    Dr. Fahy earned his B.S. from the University of California at Irvine in 1972 and his Ph.D. from the Medical College of Georgia in 1977 for work on basic aspects of cryobiology. He spent the next 18 years developing methods for preserving whole organs at cryogenic temperatures at the American Red Cross in Maryland. In 1980, he conceived of preserving organs by vitrification. He published the first proof of principle of this concept in Nature in 1985 using mouse embryos as a model system, an event that led to the wide use of vitrification in academic and commercial animal husbandry as well as in human assisted reproduction. In 1995, he won the Grand Prize for Medicine from INPEX for his invention of the first effective computer-operated equipment for perfusing organs with cryoprotective agents. The same year, he left the Red Cross to become Chief Scientist of two biotechnology companies and the Head of the Tissue Cryopreservation Section of the Transfusion and Cryopreservation Research Program at the Naval Medical Research Institute in Bethesda, Maryland. In 1998, he became the Chief Scientific Officer and Vice President of 21st Century Medicine, where he invented several new principles in cryopreservation that have been extraordinarily effective in practical applications ranging from tissues to whole organs. Dr. Fahy's efforts have recently raised the question of whether human suspended animation might be an attainable goal that could allow the human species to survive in deep time as a result of enabling migration from the earth to other habitats in the cosmos.

    Dr. Fahy is a sought-after speaker and problem-solver. He is on the Board of Directors of several organizations concerned with cryopreservation or aging, serves on the Editorial Board of Rejuvenation Research, and has served as a reviewer for numerous journals and granting bodies. He has over 20 patents in fields related to cryopreservation, aging, transplantation, metabolic protection, and the reversal of autoimmunity and immunosenescence, and has many publications in the fields of cryobiology, aging, and nanotechnology.

    He currently serves as Director for Intervene Immune, Inc. Learn more about the projects they are working on and how to become a part of their clinical trials at http://interveneimmune.com/.

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


    The Future of Longevity Research – an Interview with Dr. Aubrey de Grey – Episode 5 Dec 04, 2017
    Show notes

    Dr. Aubrey de Grey is a biological gerontologist on a crusade to defeat aging. He thinks we are within a couple of decades of rejuvenation medicine capable of adding another 30 years to human lifespan, proposing that the first person to live to 1,000 years old may already be alive today.

    In the field of longevity science, there are a few roadblocks, but the biggest one is funding. They discuss why it isn't a higher priority for average people to further this research.

    Mark and Dr. de Grey cover a number of concepts at the forefront of anti-aging, such as whether increasing telomere lengths may be beneficial against aging or may cause side effects.

    Dr. de Grey suggests we learn more about the subject of defeating aging. Then become an advocate for the research, to bring about these medicines faster.

    Mark also asks Dr. de Grey about the morality of pursuing greater longevity for humans.

    Also on the podcast, Mark and Dr. Gladden discuss how the typical medical approach isn't designed to promote longevity but treat the immediate problem. Medicine is still, after all, a business. Reimbursement is always going to trump research.

    They consider de Grey's focus on finding a big breakthrough, versus the approach of making what you have better now, along the way.

    For more information on This Week in Longevity Science, visit https://news.osu.edu/news/2017/08/07/regenerative-med-study/. Dr. Gladden expands on the function of stem cells in regard to these new findings.

    Ask yourself, "How does it change your thinking about the structure of your family, your work, community, etc., when you consider the ability to live 120 robust years?"

    About the guest:

    Dr. de Grey is the biomedical gerontologist who researched the idea for and founded SENS Research Foundation. Learn more at http://www.sens.org/. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.

    Follow de Grey on Twitter @AubreydeGrey and Facebook: https://www.facebook.com/drdegrey/

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


    The Power of Thinking Longevity is Possible – an Interview with Dan Sullivan – Episode 4 Dec 04, 2017
    Show notes

    Dan Sullivan's Strategic Coach® program is how Mark and Dr. Gladden met, and Sullivan describes how he came to imagine a different kind of longevity than most people. He talks about how just thinking differently about the possibilities and changing his mindset about aging has helped him feel better and more capable of achieving his goal of living to 156.

    In Strategic Coach, Sullivan says, "Your eyes only see and your ears only hear what your brain is looking for," which applies directly to the mindset you need to live much longer. In the reverse, he talks about the three factors he believes predispose you to die.

    For information on Vasper, watch this video: https://vimeo.com/159245493

    For more on This Week in Longevity Science, visit the following links:

    • http://bigthink.com/21st-century-spirituality/ketogenic-diets-promote-longevity-and-memory
    • https://www.ucdavis.edu/news/eat-fat-live-longer/

    Dr. Gladden weighs in on the ketogenic diet, offering some tips on how to approach it. However, every body works with food differently, and Gladden says that food may be the most important thing you can pay attention to for your mental and physical performance. Dr. Gladden, Mark and Robb each talk about their individual experiences with ketogenesis.

    Longevity requires the mind to be first, and then you bring your body along. Ask yourself, "What different questions would I be asking today if I knew it was possible to live a vibrant 120 years?"

    About the guest:

    Dan Sullivan is founder and president of The Strategic Coach Inc. A visionary, an innovator, and a gifted conceptual thinker, Dan has over 35 years' experience as a highly regarded speaker, consultant, strategic planner and coach to entrepreneurial individuals and groups. Dan's strong belief in and commitment to the power of the entrepreneur is evident in all areas of Strategic Coach® and its successful coaching program, which works to help entrepreneurs reach their full potential in both their business and personal lives.

    He is author of over 30 publications, including The Great Crossover, The 21st Century Agent, Creative Destruction and How The Best Get Better®. He is co-author of The Laws of Lifetime Growth and The Advisor Century.

    Dan is married to Babs Smith, his partner in business and in life. They jointly own and operate The Strategic Coach Inc., with offices in Toronto, Chicago, and the U.K.

    Follow Dan on Twitter @StrategicCoach and Facebook: https://www.facebook.com/StrategicCoach/

    For information on his business strategies and programs, visit https://www.strategiccoach.com/

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


    A Learner's Mindset – Episode 3 Dec 04, 2017
    Show notes

    One of the biggest challenge to living longer is getting over the accepted idea that people can't live well much longer than they do now. Just because we haven't seen it with our own eyes does not mean it's impossible. We must take the first step to ask the right questions rather than being confined by our own experiences.

    Mark talks about what some researches have concluded about a change that happened in the history of humans that may have caused a dramatic change in average lifespan.

    They reveal one of the most dangerous products/pollutants ever made that finds its way into our systems, discuss just how important water is and suggest what you should be drinking.

    They also start considering some of the many problems with the current insurance and "healthcare" systems, showing how living to 120 means you'll be an outlier working outside of those systems.

    Cancer is something that can be detected much sooner than most doctors ever test for, and Dr. Gladden talks about what helps cancer thrive that we can eliminate or reduce from our diet.

    They also conclude how health and aging relate to one another.

    For more information on This Week in Longevity Science, visit:

    https://www.sciencedaily.com/releases/2017/06/170621103123.htm

    Dr. Gladden weighs in about this news regarding olive oil and what you should and should not do with the popular ingredient.

    Finally, ask yourself, "What can I do to cultivate a mindset that enables me to believe I can function at a younger age?"

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


    Where Do I Start Living Beyond 120? - Episode 2 Nov 29, 2017
    Show notes

    Living beyond 120 years doesn't mean just flipping a switch, but it requires a slow on-ramp of changing your habits. However, this journey should start today at whatever condition your body is currently in.

    Diet and exercise isn't a one-size fits-all prescription for every person, as genetics play an important role in how your body processes certain foods and responds to different physical activity. Precision is the key to real health optimization.

    When it comes to eating well, we need to start thinking of food as a means to support our mission of health. This doesn't mean becoming a fanatic about food, but Dr. Gladden and Mark explain what foods should be avoided and how to choose better nutrition and establish better eating strategies.

    They suggest sustainable changes that you can make now to begin your path to healthy longevity.

    Read more about This Week in Longevity Science: http://www.independent.co.uk/life-style/health-and-families/health-news/scientists-key-to-longevity-italy-acciaroli-centenarian-mediterranean-diet-a7230956.html

    To learn more about 23andMe® genetic analysis: https://www.23andme.com/

    See how to apply your genetic findings to your health plan at NutraHacker: https://nutrahacker.com/

    Learn about the type of activity your physiology benefits from here with Athletigen: https://athletigen.com/

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


    What Does Living Beyond 120 Really Mean? – Episode 1 Nov 29, 2017
    Show notes

    Where does the goal of 120 years come from? What does it really mean to live that long?

    Host Mark Young and longevity expert Dr. Jeffrey Gladden explain the basics of what people need to extend their health span farther than most people ever realize is possible.

    They consider the evidence that proves what the body is capable of and the "astronaut mindset" that we need to achieve it. Dr. Gladden explains the impact of our genes and how much you can control the fate of your own health, including focusing on the overall eco-system of your body.

    The current health care system is a broken one, where it only treats sick people. Dr. Gladden explains what changed his thinking about his own health and that of his patients. He started shifting his approach and learning how to improve health.

    Read more about this week in Longevity Science: http://www.einstein.yu.edu/news/releases/1200/maximum-human-lifespan-has-already-been-reached-einstein-researchers-conclude/

    What would you do if you had an extra 40 or 50 years of lifespan?

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.


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