Gladden Longevity Podcast

Latest Episodes:

AI + Early Detection = 😎 - Episode 187 Jul 06, 2023

Show notes

What are the questions your listeners should ask themselves and their doctors right now that could save their lives? Dr. Jeffrey Gladden and Joe Bhakdi discuss that in this episode of the Gladden Longevity Podcast. Jo Bhakdi is the Founder and CEO of Quantgene with the mission to extend the healthy human life span by a decade within a decade. Together with Quantgene's team of scientists and engineers, he is dedicated to introducing cloud, AI, and precision diagnostics into the standard of care to enhance the quality and accessibility of care for everyone and protect human life. Born to scientist parents, Jo grew up with a backdrop of medical research before earning a Master's in Economics from Tubingen University, one of Germany's leading academic institutions. Prior to Quantgene, Jo held executive positions at BDDO and Omnicom with a focus on business model innovation and technology, then founded i2X. This investment platform provides quantitative analytics for biotechnology and technology portfolios. This episode discussed early detection – how it can save lives and how being vigilant can protect you for years to come. They also delve into how there is a care gap in American health care and what can be done to mend it. Should health care be a priority for everyone for a longer life?

Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!

DISCOUNT: Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop (https://gladdenlongevityshop.com/)

-- Dr. Gladden talks about today's podcast interview with Jo Bhakti on the preemptive diagnosis. (00:31) Dr. Gladden speaks about what he has learned about heart attacks. (4:25) Human money comes with strings attached, and caution is needed. (06:36) Dr. Gladden says cheating is a function of stakeholders' investment and interest in the outcome. (8:40) Interest in medicine led to studying economics, strategy, innovation, and venture capital. (11:09) Jo gives details about his journey and starting a new company. (13:43) Jo gives insight that risk is not a bad thing but it means volatility. (14:53) Jo takes us through what Quantgene does. (17:10) DNA sequencing: How it works and challenges. (20:13) Dr. Gladden notes to find something preemptively is hard work. (23:26) "Complex liquid biopsies combine high-tech modalities." (24:06) "Multiple biological ages critical for longevity". (28:39) Dr. Gladden notes that there are some hallmarks of aging. (30:48) Jo believes that cancer mutations happen before the cancer is treated. (34:30) Serenity offers an affordable early detection package. (37:16) Dr. Gladden explains that most people are afraid of being diagnosed. (40:14) Time, identity, and health. (44:12) Many people feel like a lot of diagnosis are untreatable. (46:55) Future systems watch over and optimize health efficiently. (48:43) Jo emphasizes that you need to develop systems for your health. (51:15)

Gladden Longevity Podcast Disclosures

Production & Independence

The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

Medical Disclaimer

The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

Sponsorships & Affiliate Disclosures

To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

Additional Note on Content Integrity

All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

Get The Benefits of Fasting Without Fasting? - Episode 186 Jun 29, 2023

Show notes

In this episode of the Gladden Longevity Podcast, hosts Dr. Jeffrey Gladden, Steve Reiter, and guest Chris Rhodes delve into the multi-faceted benefits of fasting, beyond metabolic factors, for overall health and longevity. Chris Rhodes is a biochemistry graduate from Loyola Marymount University and Nutritional Biochemistry PhD from UC Davis. He completed an Immunology fellowship at Stanford, where he developed a passion for longevity and anti-aging research. Initially, it seemed to be a myth, but Chris soon realized that it's a legitimate area of research with an enormous impact on disease prevention. Chris is dedicated to exploring the science behind longevity to find solutions that can solve the progression of all diseases, which is why he is Co-Founder and CEO at Mimio Health. Mimio is a nutraceutical company pioneering the world's first fasting mimetic supplement designed from clinical research to replicate the cellular health benefits of fasting without the need to fast. In this conversation, they explore fasting's profound impact on key factors such as cholesterol eFlux, inflammation, and oxidative stress while cautioning against hasty and excessive fasting practices. Rhodes provides valuable insights from his research on metabolites and their role in lifespan extension. The three also examine the positive effects of 36-hour fasting and discuss a promising CBD alternative, Pea, as a potential lifespan extender. The episode underlines the importance of consistent longevity practices and provides a comprehensive understanding of fasting as a tool for enhanced health and anti-aging.

Listen to this episode to learn about making 100 the new 30, and living young for a lifetime! --

DISCOUNT: Use promo code "gladden10" to get 10% off your first order of Mimio at http://mimiohealth.com/ !

Dr. Gladden welcomes everyone to the show. (2:27) Exciting updates on research initiatives for the audience. (02:44) Steve shares that he is so excited about the future of Gladden Longevity. (3:56) Dr. Gladden speaks about how impressed he is with Chris's thoughts and approach. (5:12) Chris goes over his background and motivations. (6:02) Study shows eating three meals beats fasting. (9:30) Dr. Gladden says fasting is incredibly helpful. (11:26) Chris points out that periods of fasting time greater than 24 hours produce better results. (13:00) Fasting triggers cell survival and rejuvenation. (14:27) AMPK activation triggers restorative functions, impacting longevity. (16:29) Dr. Gladden notes that in the longevity space, what you are doing and what you are actually doing may be two completely different things. (18:46) Chris questions the effect of some popular practices and if they are actually beneficial in the long term. (19:41) Chris highlights the benefits of fasting. (22:24) Chris talks about what happens in the body during different nutritional states. (25:37) Cholesterol eFlux: a better indicator than levels. (26:02) Dr. Gladden reminds us that PCSK9 is inherited. (29:25) Fasting benefits: cholesterol, immunity, aging, inflammation. (32:03) AI programs replaced graduate student labor used. (35:23) Chris goes over the list of ingredients they identified, including spermidine. (38:05) PEA molecule enhances mood, eases pain, and improves sports performance. (40:07) Dr. Gladden refers to different types of PEA -the micronized PEA and the ultra-micronized PEA. (43:50) There are different gradations of Pea in the way that it's processed, which is the normal Pea micronized Pea, and then the final form, which is ultra-micronized Pea. (45:04) Mimio helps suppress appetite during weight loss. (47:13) Oxytocin compliments Mimio for weight loss. (50:22) In the healthy aging space, you have things going typically the opposite. (55:03) Starting with fasting to enhance longevity benefits. (58:49) Mimio helps you optimize your fasting. (1:00:35) Dr. Gladden gives a combination that helps you stay way ahead. (1:03:40) Mimio cycling is good for the body's homeostasis. (01:05:43) You don't want to be doing the same thing every day. (1:08:04) Mimio helps mitigate stress from one meal. (01:11:37) Use the code Gladden10 to get 10% off your first order. (1:15:27) Dr. Gladden thanks Chris for the chat and promises to have more discussions as new things come to light. (1:16:05)

Gladden Longevity Podcast Disclosures

Production & Independence

Medical Disclaimer

Use of information from this podcast and any linked materials is at the listener's own risk.

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Additional Note on Content Integrity

Why You Can't Get There Without Genetics and Where to Start - Episode 185 Jun 22, 2023

Show notes

What must you look at to optimize your health and live younger for longer? Join Dr. Jeffrey Gladden, Steve Reiter, and Joe Cohen in this episode of the Gladden Longevity Podcast. Cohen experienced various health issues, such as inflammation, brain fog, fatigue, and digestive problems, which were poorly understood in traditional healthcare. Determined to find better solutions, he delved into learning about his DNA and tracking biomarkers to improve his health. This personalized approach enabled him to optimize his well-being to a level he never imagined. Inspired by his own success, Joe founded SelfDecode, the first direct-to-consumer DNA analyzer and precision health tool. SelfDecode offers accurate insights and health recommendations by utilizing AI-driven polygenic risk scoring. With over 100,000 people benefiting from SelfDecode, Joe aims to empower individuals to embrace precision health and unlock insights from their DNA and biomarkers for optimal well-being. This episode discussed health optimization, genetics, and data's role in well-being. He covered biological age, reversing it with genes and lab data. Joe also emphasized data's importance over traditional beliefs and genetics' role in understanding the body, longevity, atherosclerosis, and polygenic risk scoring, and he shared experiences with testosterone, lab tests, health optimization framework, and addressing food sensitivities. Is there a one size fits all health solution?

Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!

DISCOUNT: Use GLADDEN for 10% off any plan on your genetic testing at www.selfdecode.com

-- Dr. Gladden welcomes everyone to the podcast. (2:10) Learning to surf on a paddle board with Dr. Gladden. (02:31) Dr. Gladden says Joe is an accomplished individual. (3:10) Joe highlights the importance of good mood, energy, immunity, body, sleep, and social interactions. (06:09) Dr. Gladden asks Joe what instigated him to do genetic testing. (8:02) Dr. Gladden wants to know when Joe started doing DNA testing. (10:20) Joe shares that the critical missing piece of biochemistry is genetics. (13:18) Genetic testing refines patient care options. (14:30) Genetic testing needs high-quality sampling. (16:32) How do I improve my health? What should I do? (18:08) Genetics affects how our body responds. (20:55) The functional medicine movement is moving towards looking at individual variants and prescribing based on individual variants. (22:09) Joe says other companies are looking at a few generic variants. (24:46) The algorithm tested on public data predicts diagnoses. (26:04) Joe highlights what they do differently by sharing about imputation. (28:55) There is no 80/20 rule in science. (31:17) Genome sequencing found carrier traits; low impact. (33:00) Dr. Gladden commends Joe's company for reporting details in a way that is actually usable. (35:59) Joe explains how risk scores and recommendations work. (37:30) Joe touches on how genetics are really good as foundational data. (39:53) Genetics aren't destiny, and they adapt to the environment. (41:31) Dr. Gladden says knowing your blueprint is one thing and how it has been expressed is another one. (43:19) Joe notes that cardiovascular disease is a big killer. (45:25) Tests superseded by reverse cholesterol transport method. (46:20) Cardiovascular report: top recommendations, genetic variants. (49:37) You can do a test for any marker that is of interest to you. (52:44) TMAO is made by bacteria in the gut, and your diet determines the level. (54:00) Get summary reports for personalized health journeys. (56:04) Biology has to be balanced, and it's about getting the dose and frequency right. (59:20) Lack of security and privacy in companies. (01:02:50) Joe reveals that they have someone that focuses on data compliance. (1:04:26) DNA testing varies in accuracy and algorithm. (01:07:31) Joe emphasizes how their algorithm is better. (1:09:05) Dr. Gladden talks about where his parents came from. (1:11:39)

Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you'd like us to talk about on the podcast too! Follow us on social media! Instagram: @gladdenlongevity Twitter: @gladdenlongevit Facebook: @GladdenLongevity LinkedIn: @GladdenLongevity For more information on our practice or how to become a client, visit: www.gladdenlongevity.com Call us: 972-310-8916 Or email us: info@gladdenlongevity.com To learn more about Joe Cohen, check out the following: Website: https://selfdecode.com/ https://thejoecohenshow.com/ https://selfhacked.com/ Instagram: https://www.instagram.com/mrbiohacker/ (@mrbiohacker) https://www.instagram.com/selfdecode/?hl=en (@selfdecode) Facebook: https://www.facebook.com/selfdecode/ (@SelfDecode) Twitter: https://twitter.com/thejoecohenshow (@thejoecohenshow) LinkedIn: https://www.linkedin.com/company/selfdecode/ (@SelfDecode) YouTube: https://www.youtube.com/@thejoecohenshow/about TikTok: https://www.tiktok.com/@thejoecohenshow (@thejoecohenshow)

Gladden Longevity Podcast Disclosures

Production & Independence

Medical Disclaimer

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

Sponsorships & Affiliate Disclosures

Additional Note on Content Integrity

What Role Do Medical Foods Play in Living Young? - Episode 184 Jun 15, 2023

Show notes

What roles does sleep play in the effectiveness of nutrition? Join Dr. Jeffrey Gladden, Steve Reiter and Dr. Mike Sinel in this episode of the Gladden Longevity Podcast. Dr. Mike Sinel completed his residency at Cornell University Medical Center & Memorial Sloan Kettering in New York. Dr. Sinel served as Director of Outpatient Physical Medicine at Cedars Sinai Medical Center—an Asst. Clinical Professor at the UCLA School of Medicine, he was also privileged to work closely with chiropractors and owned several medical/chiropractic integrative clinics. In addition, Dr. Sinel lectured on alternative approaches to pain and the mind-body connection at well-known institutions, including UCLA and the Esalen Institute. As a nationally recognized expert in spinal disorders and pain management, Dr. Sinel also authored several scientific articles and two well-known books on back pain, including Back Pain Remedies for Dummies. He is the owner of Physician Therapeutics. He is passionate about reducing the side effects of pharmaceuticals by bringing safe, scientifically proven, encapsulated medical foods as natural alternatives for pain, sleep, obesity, neuropathy, fatigue & cognitive decline. In this episode, they discuss the role of skin care for chronic diseases. As the podcast progresses, they talk about how food can affect chronic inflammation/issues, the mistakes people make when first addressing their need for different nutrition, and the use of medical foods to introduce and maintain optimal nutrition in people living with chronic conditions. How do we use food as medicine or wield amino acids for better health?

Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!

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Dr. Gladden introduces Dr. Mike Sinel, an integrative medicine doctor. (02:19) Dr. Gladden tells Dr. Mike how he feels about doing things differently. (03:53) Back pain mystery; need for holistic treatment. (06:02) Dr. Mike shares how he became a yoga practitioner twenty-five years ago. (07:55) Spirituality and wellness intersect in healing. (09:27) Dr. Mike believes that, to some level, we are all energy. (10:23) Dr. Mike says getting into deep yoga practice was his first thirst for spirituality. (12:03) Holistic medicine references, integrating community resources. (14:24) Encapsulated medical foods balance cellular nutrient demands. (16:40) Dr. Mike thinks amino acids are the precursors to neurotransmitters. (18:56) Safe, effective medical foods with no side effects. (21:04) Dr. Mike says there is a risk-benefit analysis to it. (24:24) Effective therapy for pain at a discounted price. (25:13) The medical officer prescribes Centre AM for fatigue. (27:33) Dr. Gladden explains that you don't want to confuse amino acids with dietary proteins. (28:39) Dr. Mike shares that many people don't have the ingredient they put on their labels or products. (31:48) Regenerative medicine, important basics, biohacking. (32:51) Rapamycin and a-carbo improve longevity. (33:54) Dr. Gladden explains how to deal with sugar. (34:54) Dr. Gladden thanks Mike for being on. (37:15) Mike thanks Steve and Dr. Gladden. (37:55)

Gladden Longevity Podcast Disclosures

Production & Independence

Medical Disclaimer

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

Sponsorships & Affiliate Disclosures

Additional Note on Content Integrity

Ageless Skin: The Connection Between Skincare and Longevity - Episode 183 Jun 08, 2023

Show notes

Do you know how to take care of your skin? Or the current mistake you are making? Join Dr. Jeffrey Gladden and Amitay Eshel in this episode of the Gladden Longevity Podcast. Amitay Eshel is an entrepreneur in the biohacking and beauty fields. He has held executive roles in the health, wellness, and beauty industry for over a decade and has been a business development consultant in that space. As Co-founder and CEO of Young Goose, the biohacking skincare company, and host of the Young Goose's Biohacking Beauty podcast, Amitay has been making waves in his industry through education and innovation. Young Goose embodies his two passions, performance optimization and skin health, with products that boost the functions of natural rejuvenation processes in the skin. In this episode, they discuss skincare, longevity, and best practices for the best skin. As the podcast progresses, they talk about advances in skincare, the difference in approach with Young Goose, and how skincare plays into longevity. Next, Amitay Eshel delves into the science of senescent cells and their implications on aging. Eshel examines how these cells become a big driver of aging as we grow older and infect healthy cells, leading to an accumulation of senescent burden on our skin that drives whole-body aging. He discusses the importance of eliminating these cells from areas exposed to environmental toxins and even reveals that a serum aimed at removing these cells exists. So, what can you do immediately for your best skin?

Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!

DISCOUNT: Get 10% OFF your skin performance products at https://www.younggoose.com/AGEHACKERS using the code: AGEHACKERS10

Steve gives an overview of the discussion with Amitay Eshel. (00:38) Dr. Gladden introduces Amitay Eshel and shares his focus. (3:30) Amitay shares how he started off his career. (6:00) Amitay says that most people like to give labels to things. (7:37) There is a physical toll of special forces training. (8:00) Amitay speaks about navigation training as one of the more difficult trainings. (10:05) Building resilience is the key to success. (11:31) Amitay notes that you are not aging linearly. (13:44) Amitay explains that the question they get the most is – 'How fast do I see a difference?' (15:47) Stress ages people quickly, so best to think of resilience first. (17:04) Dr. Gladden reveals that the antidote to aging is being youthful. (18:48) Red light therapy is an amazing technology. (21:03) Amitay states that one of his favorite topics is senescent cells. (23:47) Amitay gives examples about not being able to mimic the facial expression of others because of the heavy use of Botox. (25:04) Science has shown that people can look at you and infer your biological age. (27:43) The way you treat yourself from the inside will affect the way your skin is. (29:30) Dr. Gladden asks Amitay to talk about how senescence is measured. (31:12) Amitay discloses that one can also have leaky skin. (32:56) Steve asks how you know if your skin isn't detoxifying well, and Amitay shares expert tips for detoxifying for clearer skin (34:37) Amitay clarifies the use of coconut husk. (38:36) Dr. Gladden mentions GHKCU use. (41:28) Amitay says what we call epigenetic expression is true. (45:05) Peptides and marine compounds are the ultimate collagen boost. (47:25) Amitay has a system that he has developed to upregulate certain genetic expressions. (49:18) Amitay emphasizes that the skin cannot break down resveratrol. (51:38) Eliminating senescent cells is a key to slowing aging. (54:30) Amitay lists areas in our body where we can find most senescent cells. (56:12) Amitay explains that the young goose does not grow older after a certain age. (1:00:34) Dr. Gladden thanks Amitay for being on the show. (1:03:25) Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you'd like us to talk about on the podcast too! Follow us on social media! Instagram: @gladdenlongevity Twitter: @gladdenlongevit Facebook: @GladdenLongevity LinkedIn: @GladdenLongevity For more information on our practice or how to become a client, visit: www.gladdenlongevity.com Call us: 972-310-8916 Or email us: info@gladdenlongevity.com To learn more about Amitay Eshel and Young Goose Skincare, check out the following: Website: https://www.younggoose.com/ Facebook: @YoungGooseSkincare https://www.facebook.com/younggooseskincare Instagram: @young_goose_skincare https://www.instagram.com/young_goose_skYincare/ YouTube: https://www.youtube.com/@younggoose4113 LinkedIn: @AmitayEshel https://www.linkedin.com/in/amitay-eshel/

Gladden Longevity Podcast Disclosures

Production & Independence

Medical Disclaimer

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

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Additional Note on Content Integrity

The Best Info on Peptides You've Ever Heard - Episode 182 Jun 01, 2023

Show notes

Do you know that supplementing NAD or glutathione with frequent IVs might be hurting your cell's ability to adapt? Join Dr. Jeffrey Gladden, Steve Reiter and Dr. Seeds in this episode of the Gladden Longevity Podcast. Dr. Seeds is a board-certified orthopedic surgeon practicing medicine for over 27 years and the Founder and Medical Director of the Seeds Scientific Research & Performance Mastermind. He has been honored at the NFL Hall of Fame for his medical expertise and in treating professional athletes. He serves as Professional Medical Consultant for the NHL, MLB, NBA, and NBC's Dancing with The Stars. Dr. Seeds is also a medical researcher and continues to write and publish in the NIH and other medical journals. He is also the author of Peptide Protocols Vol.1, the world's first handbook about peptides written for practitioners. Today at the Seeds Scientific Research and Performance Institute, he is dedicated to bringing Cellular Medicine and the study of Epigenome to the forefront of the medical community through research, training, and improved patient outcomes. His practice is at the Olympic training facility: Spire Institute Geneva, OH, and at the Redox Medical Group, Beverly Hills, CA. This episode discusses how cellular redox is quickly going to become the health goal and how this is where disease, aging, and cancer starts, and that it is also where we can find solutions. As the podcast progresses, they talk about our cell's main job, the balance and the imbalance of oxidation and reduction, and the benefits of achieving cellular redox. They explore various peptides and their ability to maintain homeostasis of redox, improve gut health, decrease anxiety, and aid in recovery after injury or training. Moreover, they touch on the importance of addressing gut health to tackle immune issues and offer dosage recommendations for peptides.

Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!

Dr. Gladden mentions that Seeds was the one that certified him in peptides. (1:15) Dr. Gladden explains that we make peptides in our bodies. (2:24) Dr. Gladden welcomes Dr. Seeds. (4:10) Dr. Gladden explains cellular redox. (6:14) Dr. Seeds shares that his mission was to introduce people to cellular medicines. (8:09) Dr. Seeds speaks about making microfilaments in a cell to keep the structure of the cell symmetrical. (10:35) Dr. Seeds shares that if you're regulating the infrastructure of a cell to keep it at its optimal, and you're keeping the signaling at its optimal, then you're reducing cellular redox issues, and you're reducing problems that create, like fibrosis. (12:40) Dr. Gladden asks Dr. Seed about the interplay between GHKCU and BPC 157. (15:40) Dr. Gladden discloses his observations that injuries seem to heal faster with the use of peptides. (18:03) Dr. Gladden shares that he wakes up feeling 27 every day. (19:50) Dr. Gladden goes over what being nominated means. (21:25) Dr. Gladden emphasizes that people could make a case for using BPC on a daily basis. (24:13) Dr. Seeds says T-regs cells are masters of immune tolerance. (28:00) Dr. Seeds reveals the discovery of zonulin, which is a toxin from the cellular connection in the bowel. (32:25) Dr. Seeds advises that people need to focus on the gut with lots of immune issues. (35:15) Dr. Seeds discloses a peptide that helps with leaky gut. (37:36) Dr. Seeds speaks about one of the best peptides available that can be used intranasal or subcutaneously. (41:28) Dr. Seeds reveals that BDNF is a big player in anxiety and depression. (44:10) Dr. Seeds advises that you must be careful with CMAX because it's more of an activator. (47:40) Dr. Seeds refers to how working with younger kids is a game changer. (50:25) Dr. Seeds says there are good and bad aspects of nicotinamide. (54:25) Dr. Seeds spells out one of the best peptides we have if you know how to use it. (57:00) Dr. Seeds refers to an incredible peptide that only needs to be used for short periods. (59:00) Steve announces that Dr. Seeds has a book on peptides and thanks everyone for listening. (1:00:07)

Gladden Longevity Podcast Disclosures

Production & Independence

Medical Disclaimer

Use of information from this podcast and any linked materials is at the listener's own risk.

Podcast Guest Disclosures

Sponsorships & Affiliate Disclosures

Additional Note on Content Integrity

Can This Blood Test Tell if You Are Going to Have a Heart Attack? - Episode 181 May 25, 2023

Show notes

Do you know the #1 killer of people in the US that kills more people than all cancers combined? Join Dr. Jeffrey Gladden, Steve Reiter, and Rhonda Rhyne in this episode of the Gladden Longevity Podcast. Rhonda Rhyne is a highly accomplished healthcare executive with a Bachelor of Pharmacy and an MBA. Most of her career has been spent in cardiovascular medicine and industry, primarily in medical devices. With experience in General Electric Medical Systems and Cardiodynamics, she became fascinated by the biomarker world, particularly non-invasive cardiac output and single biomarkers such as BNP. Rhonda then became the CEO of Prevencio, leading the company towards developing multi-analyte or multi-protein tests after seeing the potential of these combinations. In this episode, they discuss current diagnostic testing modalities, including exercise/echo/nuclear stress tests, coronary artery calcium scores, cholesterol, single protein blood tests, and genetic scores that have lower accuracy as compared to AI-driven multiprotein blood tests. As the podcast progresses, they look at how Prevencio's HART blood tests were developed through the use of AI to select and combine multiple proteins and optionally clinical parameters in an algorithm and scoring system that has almost 90% accuracy for detecting whether you have heart disease and are at imminent risk of heart attack (HART CADhs), or one year risk of heart attack, stroke or cardiac death (HART CVE). They discuss the negative effects of alcohol on sleep and exercise routines, as well as how the enzyme alcohol dehydrogenase can contribute to aging. Rhonda shares their experience conducting cardiopulmonary exercise tests and strategies for protecting kidneys during contrast dye exposure. We dive into the importance of identifying insulin resistance and understanding genetic expression in predisposition to cardiovascular disease. Finally, we look at a new algorithm combining six parameters for a more accurate diagnosis of coronary artery disease. Do you know you can use the HART tests as a baseline to track and trend your hopeful improvement or deterioration of your heart?

Listen to this episode to learn about making 100 the new 30 and living young for a lifetime!

Dr. Gladden welcomes everyone to the show and shares how he met Rhonda (2:15) Rhonda shares how she got into what she presently does and her background. (3:15) Through proteins, we see how a genetic expression is. (5:33) Dr. Gladden highlights that high-sensitivity troponins and other proteins are being identified as potential markers for heart disease. (7:03) Dr. Gladden observes troponin levels rise in people who exercise but not exercising may show normal ranges. (9:55) Dr. Gladden shares how adiponectin protects arteries from oxidative stress. (12:22) Rhonda reveals that they fed machine learning all the proteins they could get. (14:30) Heart health comes down to a lot of things, not just one. (16:25) Rhonda says they are in the process of collecting data and doing case studies. (18:52) Gene expression can be modulated to achieve balance in the body's complex ecosystem using custom peptides. (21:42) Dr. Gladden says, in his practice, one of the issues he faced was taking care of people's kidneys. (23:28) Rhonda gives information about a test that is not commercialized yet but is just in the process. (26:56) Steve asks about the long-term effects of what Dr. Gladden mentioned. (27:40) Rhonda says the PAD will soon be available. (29:40) Rhonda discloses that, in August, she will have been with the company for ten years. (31:11) Dr. Gladden insinuates that there is a lot more to insulin levels than people realize. (33:23) There are no side effects in getting a simple blood test. (35:26) Rhonda talks about the accuracy of their tests compared to traditional ones. (38:02) Rhonda thanks Steve and Dr. Gladden for the podcast. (38:50)

Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you'd like us to talk about on the podcast too! Follow us on social media! Instagram: @gladdenlongevity Twitter: @gladdenlongevit Facebook: @GladdenLongevity LinkedIn: @GladdenLongevity For more information on our practice or how to become a client, visit: www.gladdenlongevity.com Call us: 972-310-8916 Or email us: info@gladdenlongevity.com To learn more about Rhonda Rhyne and/or Prevencio, check out the following: Website: https://prevenciomed.com/ Phone Number: (425) 576-1200 Linked: https://www.linkedin.com/company/prevencio-inc./ (@PrevencioInc) Facebook: https://www.facebook.com/Prevencioinc/ (@PrevencioInc) Youtube: https://www.youtube.com/channel/UCurfuy5rBjtc-ShYs_Aetpg Twitter: https://twitter.com/RhondaRhyne DISCOUNT: Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop (https://gladdenlongevityshop.com/) Get the supplements mentioned in this episode! CoQ10: https://gladdenlongevityshop.com/products/super-ubiquinol-coq10-100mg-60-softgels?_pos=1&_psq=coq&_ss=e&_v=1.0 Berberine: https://gladdenlongevityshop.com/products/berberine-60-count?_pos=1&_psq=berberine&_ss=e&_v=1.0 Bergamot: https://gladdenlongevityshop.com/products/bergamot-bpf-60ct?_pos=1&_psq=berga&_ss=e&_v=1.0

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How to Access Care Not Covered by Your Insurance - Episode 180 May 18, 2023

Show notes

Join Dr. Jeffrey Gladden, Steve Reiter and Joe Baffone in this episode of the Gladden Longevity Podcast. Joe is Co-Founder and CEO of Annexus Health, the leading healthcare technology company that is revolutionizing the patient access journey by delivering innovative solutions that reduce financial and administrative burdens to improve access, speed, and adherence to critical care. In his role as CEO, Joe takes a servant-leader approach and is as passionate about empowering others as he is about breaking down barriers to patient care. His work overseeing business development, strategy, and culture at Annexus Health is informed by over two decades of experience working in life sciences. Most recently, prior to co-founding Annexus Health, Joe spent seven years as a principal at onPoint Oncology, where he concepted, built, implemented, and monetized cancer access solutions. A devout Christian, Joe relies on his faith, which is central to his personal and professional decision-making. He and his wife, Jeanie, have three children, one of whom Joe has the privilege of working with at Annexus Health. This episode discusses improving the management of the patient care journey in complex disease states and the impact on longevity. As the podcast progresses, they talk about the administrative and financial challenges of the patient care journey in complex disease states as having an outsized impact on longevity. In addition, they consider the meaningful impact in complex disease states that requires provider centricity to be patient-focused and outcome-driven and that disruptive ecosystem-conscious technology approaches can be the most meaningful innovation in our healthcare system.

Listen to this episode to learn about making a 100 the new 30 and living young for a lifetime!

Dr. Gladden welcomes everyone to the podcast. (1:55) Dr. Gladden welcomes Joe to the show. (2:37) Dr. Gladden clarifies if Joe was the primary caregiver for his mom. (4:02) Joe mentions how his grandfather passed away from colorectal cancer. (6:18) Joe details some of the cool things that have happened in his career. (8:51) Dr. Gladden points out how doctors are caught in the middle between pharmaceutical companies' high cancer drug costs and consumers who cannot pay for them. (10:48) Joe explains repurposing data from other sources. (12:58) Dr. Gladden talks about drugs in the pancreatic space that are so expensive but only help patients live two months longer. (15:18) Joe shares that they have fourteen disease states but that they started with cancer. (17:01) Dr. Gladden discusses giving away care for free and keeping a business afloat. (19:58) Joe says that patient outreach is a critical path they are developing. (21:19) Joe reiterates that outreach is critically important, but they still believe it funnels through the provider. (23:38) Joe speaks about how the nonprofit world is challenging to work through to get to the decision-makers. (25:34) Dr. Gladden asks Joe about his plan for the fourteen disease states going forward. (28:14) Joe presents his vision of creating a technology network using its administrative enterprise platform to communicate well with other systems. (30:48) Dr. Gladden wants to know if there is a focus on mental health to get people mental health services. (32:30) Joe highlights one thing patients should do, and it involves owning their healthcare and understanding there are options to help them with challenges. (34:51) Dr. Gladden gives examples of commercial insurance. (36:00) Dr. Gladden notes that many patients are willing to control their healthcare, but what they don't own is the backend of it. (38:19) Dr. Gladden thanks Joe for bringing this information forward. (44:16) Joe thanks everyone. (44:53)

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From Emergency Medicine to Making 100 the New 30 - Episode 179 May 11, 2023

Show notes

Join Dr. Jeffrey Gladden, Steve, and Dr. Ernie Navarro in this episode of the Gladden Longevity Podcast. Ernie Navarro is a Medical Doctor working for Gladden Longevity and has previously worked with Questcare Partners, Envision Health, and Metropolitan Hospital, and studied at New York Medical College. In this episode, you get to hear Dr. Navarro's story, how he ended up at Gladden Longevity, and the impact of Covid vaccines and boosters on aging and longevity. Listen to find out more.

Listen to this episode to learn about making 100 the new 30 and living beyond 120!

Show notes: Dr. Gladden welcomes everyone to the podcast and introduces Dr. Ernie Navarro. (2:00) Trained as an emergency physician, Dr. Gladden asked Dr. Navarro pushed him to think outside the box. (3:05) Dr. Navarro shares that what he missed about ER were the people he worked with and their fun personalities. (4:32) Dr. Gladden shares how medicine has changed over the years and the increased cost of medical care. (6:15) Dr. Gladden reveals that medicine has changed because of the many administrative burdens on doctors. (8:00) Some of the coordinators in the hospital have experience in the medical line but are mostly focused on profit. (10:22) Dr. Gladden reveals how the many administrative duties put on doctors lead to burnout. (12:30) Dr. Navarro shares how his sister was diagnosed with breast cancer at a very young age and had to undergo treatment. (14:08) Dr. Navarro details how his sister passed away from the return of cancer. (15:59) Dr. Navarro said he got tired of the day and night schedule and needed something different. (18:55) Dr. Gladden talks about how he went without pay for four and half years trying to build Gladden Longevity. (22:30) Dr. Navarro discloses that he has had moments where he has doubted himself. (25:24) Dr. Navarro shares insights about the impact that people share that keeps him going. (29:25) Dr. Gladden discloses what he loves about Dr. Navarro. (33:00) "What might have been best last year might not be best this year." (36:10) Dr. Navarro explains that for people getting boosters, their biological age bumps to over fifteen years older. (43:08) Dr. Gladden shares how telomeres shorten after people take boosters. (45:16) Dr. Navarro points out how the booster is not serving anyone at this point. (50:15) The consequence of the Covid vaccine is different from all other vaccines. (53:10) Dr. Gladden shares that too much growth hormone is in itself an aging process. (55:47) Steve thanks everyone for the conversation. (59:12) Dr. Gladden emphasizes that to work with Gladden Longevity, you can just reach out through the website, and you will get a response. (1:00:15) Dr. Navarro points out that mindset is really important in succeeding as a client with Gladden Longevity. (1:01:25) Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you'd like us to talk about on the podcast too! Follow us on social media! Instagram: @gladdenlongevity Twitter: @gladdenlongevit Facebook: @GladdenLongevity LinkedIn: @GladdenLongevity For more information on our practice or how to become a client, visit: www.gladdenlongevity.com Call us: 972-310-8916 Or email us: info@gladdenlongevity.com To learn more about Ernie Navarro, check out the following: Linkedin: https://www.linkedin.com/in/ernesto-navarro-m-d-819b5458 DISCOUNT: Podcast10 (10% off your purchase at the Gladden Longevity Supplement shop https://gladdenlongevityshop.com/) Get the supplements mentioned in this episode! Arterosil: https://gladdenlongevityshop.com/products/arterosil-60ct?_pos=1&_psq=arterosil&_ss=e&_v=1.0 Molecular Hydrogen: https://gladdenlongevityshop.com/products/h2-molecular-hydrogen-30-ct?_pos=1&_psq=hydrogen&_ss=e&_v=1.0 Melatonin: https://gladdenlongevityshop.com/products/melatonin-20mg-60ct?_pos=2&_psq=melatonin&_ss=e&_v=1.0 SPM: https://gladdenlongevityshop.com/products/spm-active-120ct?_pos=1&_psq=spm&_ss=e&_v=1.0

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Is This Better Than Growth Hormone? - Episode 178 May 04, 2023

Show notes

Do you need to establish beginning biomarkers to measure improvements? Join Dr. Jeffrey Gladden and Dustin Baker in this episode of Gladden Longevity. Dustin Baker is the President of BioProtein Technology and creator of BioPro+. With years of experience working intimately with some of the world's most elite professional athletes, trusted physicians, and even international private security / military personnel, his passion remains to help individuals maximize their physiological and cognitive potential safely. Since his 20s, Dustin has been instrumental in the product design and brand development for natural products in the professional athletics, fitness, and medical supply categories. This episode discusses Human Growth Hormone, what it is, what it does, and its benefits and liabilities. As the podcast progresses, they talk about its decline as you age and how you can improve it naturally or with help. In addition, they consider risk factors with synthetic Rx treatments, the availability of other options that are not necessarily synthetic, and the importance of feeling, looking, and performing your best personally and professionally. Listen to find out more.

Listen to this episode to learn about making 100 the new 30 and living beyond 120!

Dr. Gladden welcomes everyone to this edition of the show and welcomes Dustin. (2:07) Dustin says health and nutrition education for children is nonexistent. (4:36) Dr. Gladden notes that "crappy" food is less expensive than quality food. (5:50) Dustin mentions that his weight issues led to bad habits. (8:05) Dustin emphasizes that he always mentions his friend who first motivated him to take fitness seriously. (10:17) Dustin explains that the slightest show of appreciation can significantly impact people's lives. (13:45) Dustin retrospects about how some time back, he never went outside his comfort zone to get better. (15:40) Dustin describes his first mentor, whose entire business was built around human performance. (17:45) Dustin shares that as time passed, he got contracts, referrals, and more jobs based on his previous job and performance. (19:47) Dustin shares that growth factors are cell signals that signal cells to do stuff. (21:40) Dustin highlights his passion of giving men over the age of thirty-five their life back. (23:16) Dustin goes over how living growth factors are extracted from other mammals. (25:24) Dustin discloses that IGF1 seems to be the popular growth factor. (27:48) Dustin comments that IGF is really cool, and it's always good to take a look at what IGF efficiency looks like. (29:26) Dr. Gladden shares an interesting point about how growth factors can promote cancers. (31:53) Dr. Gladden points out that there is a balance of growth factors that are needed. (33:17) Dustin speaks of how Russians are heavily invested in their people's human performance and longevity. (35:33) Dustin tells us how they receive orders from all around the world. (37:07) Dustin reveals that one out of three men suffers from erectile dysfunction issues. (38:55) Dr. Gladden emphasizes that there is no downside to sexual activity. (40:22) Dr. Gladden asks Dustin to list some of the top benefits of the product. (43:25) Dustin recounts the testimony of an athlete who changed his life using the product. (46:18) Dustin expresses how a government agency has been using and testing the product with its elite team. (48:24) Dustin speaks about how physicians were using the BioPro+ for their TRT patients and noticing improvements. (51:23) Dr. Gladden thanks Dustin for his time. (54:14)

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