In this fascinating study from UCSD, researchers demonstrate for the first time that time-restricted-feeding (TRF), or intermittent fasting, can synchronize neuronal tissue clocks. This results in the Alzheimer's disease mice to have better sleep, improved sleep length, less irritability, better metabolic dynamics, reduced plaque load and improved plaque clearance, and improved abeta42/abeta40 ratio, with memory improvements almost equal to healthy mice. Let's review.
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References (Aug. 25, 2023)
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Overview of Circadian Rhythms - PMC
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Zeitgeber times (ZT) when NOR tasks were carried out. ZT 0 corresponds... | Download Scientific Diagram
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What's Tau Got to Do With it? - InVivo Biosystems
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The Use of Mebendazole in COVID-19 Patients: An Observational Retrospective Single Center Study - PMC
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High Morning Blood Glucose | ADA
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IJMS | Free Full-Text | Phosphorylation Signaling in APP Processing in Alzheimer’s Disease
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