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    Alternative Health

    Biohacking Beauty: The Anti-Aging Skincare Podcast

    Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond “single-molecule” trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ.

    We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.

    Advertise

    Copyright: © Copyright 2026 Young Goose

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    Latest Episodes:
    Dr. Doris Day: Reverse Skin Aging By Fixing Inflammation Nov 26, 2025
    Show notes

    We’ve always said that healthy skin starts from within, but few people understand how deeply skin and longevity are connected. Every wrinkle, blemish, or loss of elasticity begins with inflammation and cellular stress that ripple throughout the body.

    In this episode, we sit down with world-renowned dermatologist Dr. Doris Day to explore how the skin doesn’t just reflect your health, it drives it. From managing inflammation to restoring collagen through sleep, nutrition, and resistance training, Dr. Day reveals why true skin longevity starts at the cellular level.

    We also discuss the rise of prejuvenation, the science behind Softwave and exosomes, and how new molecules like RLX201 (ReQ) are changing the way we approach aging. Dr. Day shares how to rethink fillers, balance hormones, and build skin health that lasts decades, not months.

    We Also Discuss:

    (00:00) Blending Dermatology, Health Optimization, and Longevity

    (04:38) How Skin Reflects and Affects Whole-Body Health

    (08:39) Stress, Cortisol, and the Skin-Brain Connection

    (10:17) The Truth About Sunscreen, Hormones, and Menopause

    (13:51) Real Prejuvenation and the Rise of Softwave

    (19:40) RLX201 (ReQ) and the Future of Skin Longevity

    (32:20) Inflammation, Oxidative Stress, and Aging Skin

    (37:56) Critical Thinking and the Future of Longevity Medicine

    (46:18) Fillers, Balance, and the Art of Subtle Enhancement

    (58:42) Longevity Habits for Better Skin and Health

    Find more from Young Goose:

    • Blue Peptide Spray: Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare

    Find more from Dr. Doris Day

    Website: https://dorisdaymd.com

    Instagram: @drdorisday

    LinkedIn: Doris Day, MD



    Fady & Marina: How Real-Time Hormone Data Extends Longevity Nov 19, 2025
    Show notes

    We’ve always believed that data drives better health, but even we were surprised by how powerful hormone data can be. Hormones influence everything from how we age to how our skin repairs itself, yet most people only test them once a year, if at all.

    In this episode, we sit down with Fady and Marina from Eli Health to explore how real-time hormone testing is changing the way we understand health optimization. Their saliva-based technology tracks cortisol and progesterone with over 90 percent lab-comparable accuracy, while their AI-powered app translates results into actionable lifestyle insights.

    We also unpack how cortisol rhythm shapes energy, mood, and skin health, why “cortisol face” is real, and how frequent hormone tracking can help prevent stress-related aging before it appears on the skin. Fady and Marina, founders of Eli Health, are redefining hormone care with a science-driven, ethically designed platform that keeps data and decisions in your hands.

    We Also Discuss:

    (01:07) How At-Home Hormone Testing Works

    (02:28) The Accuracy of Real-Time Cortisol and Progesterone Testing

    (04:20) Understanding Your Diurnal Cortisol Curve

    (07:13) AI-Powered Lifestyle Recommendations for Stress and Sleep

    (10:52) Using Hormone Insights to Personalize Your Routine

    (14:52) Cortisol, Skin Health, and “Cortisol Face”

    (19:22) The Rise of Frequent Hormone Tracking (“Fitbit for Hormones”)

    (24:11) Testosterone and Estradiol: The Next Frontier

    (37:38) Timing Skincare Treatments to Your Hormone Cycle

    (41:33) Ethics, Privacy, and Data Ownership in Health Tech

    (47:52) The Future of Hormone Tracking and Longevity

    Find more from Young Goose:

    • Blue Peptide Spray: Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare

    Find more from Eli Health

    Website: eli.health

    Instagram: @myelihealth

    LinkedIn: Eli Health


    Nathalie Niddam: Peptides, Bioregulators, and the Truth About Skin Longevity Nov 12, 2025
    Show notes

    Everyone online is talking about peptides like they’re the next collagen powder, but most people are skipping the most important part: is your body even in a state to heal?

    In this episode, we sit down with longevity expert Nat Niddam to get clear on what peptides actually are, how they work in the body, and where people are getting this conversation dangerously wrong. We talk about the difference between signaling peptides and bioregulator peptides, why inflammation and gut integrity determine whether you’ll see real results, and why “anti-aging for skin” is not as simple as injecting the trendy thing from Instagram.

    We also dig into BPC-157, TB-500, growth hormone secretagogues, and the pineal, thymus, and vascular bioregulators, including when they can accelerate repair, and when they’re a terrible idea. Nat explains why your skin is a mirror of internal stress, mitochondrial function, and recovery, and why trying to force aesthetic results on top of chronic inflammation is like trying to build a house that’s already on fire.

    Nat Niddam is a certified nutritionist, longevity practitioner, and one of the most trusted voices in the peptide and bioregulator space. She helps clients approach repair, recovery, and aging with strategy instead of guesswork.

    We Also Discuss:

    (00:01) What Peptides Really Are, and Why Everyone’s Talking About Them

    (08:45) Inflammation: The Silent Blocker That Stops Peptides from Working

    (18:58) The Longevity Stack: Bioregulators, Immunity, and Cellular Repair

    (29:39) Beginner Protocols: How to Start Peptide Therapy Safely

    (37:31) From Gut to Glow: Peptides, Healing, and Immune Support

    (51:18) The Growth Hormone Question, Repair, Recovery, and Real Risks

    Find more from Young Goose:

    • Blue Peptide Spray: Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Find more from Nathalie Niddam:

    Instagram: https://www.instagram.com/nathalien iddam

    Website: https://www.natniddam.com/


    Karin Adoni: What Most People Miss About GLP-s, Food, Inflammation, and Skin Nov 05, 2025
    Show notes

    What if the secret to better skin isn’t another serum or laser, but lowering inflammation from the inside out?

    In this episode, I sit down with Karin Adoni, a certified holistic nutritionist, to talk about how food, sleep, and everyday toxins shape the way we age. Karin shares how she turned her own recovery from eating disorders into a mission to help women rebuild their metabolism and hormone balance naturally.

    We break down why ultra-processed foods and seed oils accelerate aging, how gut health drives skin health, and why sustainable change starts with real food, clean water, and better sleep, not shortcuts.

    Karin Adoni is a certified holistic nutritionist and founder of Karin Adoni Nutrition. She specializes in helping women heal inflammation, balance hormones, and age well through realistic, empowering nutrition and lifestyle changes.

    We Also Discuss:

    (00:01) From Eating Disorders to Empowered Nutrition

    (07:44) The Real Pillars of Wellness (That Actually Work)

    (13:21) How Food and Inflammation Shape Aging

    (27:06) The Ugly Truth About “Skinny Shots” and GLP-1s

    (34:13) Hormones, Toxins, and the Hidden Drivers of Skin Aging

    (44:35) Building a Personalized Nutrition Plan That Lasts

    Find more from Young Goose:

    • Blue Peptide Spray: Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Find more from Karin Adoni:

    Website: https://karinadoni.com/

    Instagram: @karinadoninutrition/

    Tiktok: @karinadoninutrition



    Joel Marshall: Microneedling, Exosomes & Why RF Isn’t Really Microneedling Oct 29, 2025
    Show notes

    What if the best way to rejuvenate your skin isn’t lasers, peels, or expensive devices, but teaching your skin to repair itself?

    In this episode, Joel Marshall, Founder and CEO of Dp Derm joins us to reveal how modern microneedling has evolved from rollers and stamps into the precision of the Dermapen 4. We explain how controlled micro-injuries stimulate natural collagen production, break down scar tissue, and restore youthful function without the risks of heat-based treatments. He also shares why so-called radiofrequency microneedling is misleading and potentially harmful.

    We also explore the role of exosomes, NAD⁺, vitamin C, and licorice root extract in amplifying results, along with why pre-treatment preparation and post-care are essential for long-term outcomes. Joel’s mission is clear: make skin health accessible and effective through science-driven protocols, not marketing gimmicks.

    Joel Marshall is the Founder and CEO of Dp Derm, the US home of DermapenWorld, and a global leader in professional microneedling technology. He has pioneered safer, smarter, and more effective approaches to skin rejuvenation.

    We Also Discuss:

    (00:01) Microneedling Uncovered: Why Tiny Injuries Transform Skin

    (06:59) Lasers vs. Needles: Why Heat Isn’t Always Better

    (12:10) The RF Controversy: Why It’s Not True Microneedling

    (18:45) Inside the Industry: The Hidden Challenges of Microneedling

    (25:00) Exosomes Explained: The Future of Skin Regeneration

    (35:45) Supercharging Skincare: Can Microneedling Really Boost Absorption?

    (45:38) Red Light, Cold Plunge, and Microneedling—What Actually Works?

    (48:41) Truth or Hype: The Biggest Microneedling Myths Explained

    Find more from Young Goose:

    • Blue Peptide Spray – Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Amplifying Essence – Prime skin for deeper absorption → Amplifying essence
    • The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body Cream
    • Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serums
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare

    Find more from Joel Marshall:

    Website: https://dpderm.com/

    Instagram: @joel_dpderm

    Instagram: @dpderm


    GHK-Cu Explained: The Copper Peptide That Signals Collagen Repair Oct 24, 2025
    Show notes

    Most people hear “copper peptide” and think “trend”. But GHK-Cu isn’t new, it’s a naturally occurring bioregulator your body already uses to repair, rebuild, and rejuvenate skin.

    In this episode of Biohacking Beauty, we break down why GHK-Cu deserves its cult status in longevity skincare. We also unpack how this tripeptide binds copper to signal fibroblasts, activate collagen and elastin genes, and restore damaged tissue at the cellular level. You’ll learn why 3% is the sweet spot for results without irritation, how GHK-Cu works synergistically with retinol, vitamin C, methylene blue, and NAD+, and what makes pharmaceutical-grade sourcing critical for performance.

    If you’ve ever wondered whether GHK-Cu can truly “reset” aging cells or how it compares to retinol, this episode connects the dots between biochemistry and visible results, showing how small, precise molecules can drive profound, measurable change in your skin’s longevity.

    What's Discussed:

    (00:00) What makes ghk-cu more than a “trendy copper peptide”

    (02:20) How fibroblasts, collagen genes, and epigenetics work together

    (07:19) Why 3% ghk-cu is the sweet spot for results without irritation

    (10:22) Retinol, vitamin c, and ghk-cu, the synergy your skin actually needs

    (18:24) Methylene blue, nad+, and the ultimate skin longevity stack

    Find more from Young Goose:

    • Blue Peptide Spray – Cellular hydration meets antioxidant power → Blue Peptide Spray
    • The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body Cream
    • Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serum
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Can Vampire Exosomes Really Rebuild Aging Skin? Here’s the Science Oct 22, 2025
    Show notes

    Exosomes aren’t just a buzzword, they’re nanoscale messengers that deliver the body’s own repair instructions. In this episode of Biohacking Beauty, we unpack the science of platelet-derived, or “vampire,” exosomes and how they go beyond conventional growth factors to target aging at its root.

    You’ll learn how microRNA inside platelet exosomes can reduce senescence signals, trigger collagen and elastin renewal, and activate autophagy for deeper cellular repair. The hosts also explore how formulation stability, ingredient compatibility, and third-party quantification make or break an exosome product.

    If you’ve ever wondered how PRP exosomes compare to traditional PRP facials, or why pairing them with NAD-boosting actives can amplify skin longevity, this episode explains the real mechanisms behind the hype, helping you understand what it takes for skin to truly act younger, not just look it.

    What's Discussed:

    (00:00) Redefining Skin Longevity Through Cellular Repair

    (06:07) How Exosomes Became the Next Frontier in Regenerative Skincare

    (16:00) Why Platelet-Derived Exosomes Deliver the Most Potent Repair Signals

    (23:54) The Real Anti-Aging Data Behind PRP Exosomes

    (32:35) Exosomes vs. Retinoids, Fillers, and Lasers, What the Evidence Shows

    (46:30) Elevating Repair Capacity: Exosomes Meet Rejuve NAD

    Find more from Young Goose:

    • Vampire Exosomes: Experience the world’s highest-potency exosome serum here → Vampire Exosomes
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    The Skincare Ingredients That Don’t Live Up to the Hype Oct 15, 2025
    Show notes

    What if the products you’re being told to buy are doing more harm than good?

    In this episode of Biohacking Beauty, we strip it back to unfiltered opinions, no scripts, no fluff, just real talk about the ingredients and habits that get way too much attention in skincare.

    We call out why certain “hero” ingredients, like high-dose niacinamide, may actually backfire with chronic use, and why collagen powders in hot coffee aren’t the miracle they’re sold as. We dig into the over-exfoliation trap, explain why protecting your barrier is the foundation for every other biohack, and spotlight methylene blue as one of the most underutilized longevity tools for skin.

    At the end of the day, trends will come and go, but your skin cells don’t follow hype — they respond to biology. This episode will change the way you think about your routine.

    What's Discussed:

    (00:07) The skincare lies influencers keep repeating

    (00:40) Niacinamide: hero ingredient or hidden problem?

    (10:28) The next-gen ingredients that actually reprogram skin aging

    (22:08) Myths that won’t die: pores, collagen drinks & celebrity skincare lines

    (29:23) Why your skin barrier is the foundation of true longevity skincare

    Find more from Young Goose:

    • Blue Peptide Spray – Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serums
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Spirulina: The “Blue-Green” Secret Behind Youthful Skin Oct 10, 2025
    Show notes

    Most people know spirulina as a superfood: a bright green powder you toss into smoothies.

    But what happens when this blue-green algae becomes a skincare ingredient?

    In this episode of Biohacking Beauty, we go behind the science to explain why spirulina deserves a place in your longevity routine.

    We break down how its unique peptides, antioxidants, and minerals defend against oxidative stress, boost collagen, and calm inflammation, all while keeping skin hydrated and resilient. We also share how spirulina fights acne, supports barrier repair, and even offers mild UV protection.

    You’ll hear how Young Goose sources Spirulina AP, a purified, heavy-metal-free extract with clinical data behind it, and why the way it’s formulated makes all the difference between irritation and true repair.

    If you’ve ever wondered whether spirulina works better in your smoothie or on your skin, this short and science-packed episode clears it up.

    What's Discussed:

    (00:00) Blue Peptide Spray + Why Spirulina Deserves the Spotlight

    (03:42) How Spirulina Fights Aging, Inflammation, and Collagen Loss

    (07:23) Spirulina for Acne, Hydration, and Brightening

    (11:40) The Truth About Using Spirulina Orally vs. Topically

    (16:29) Is Spirulina the Next Big Skincare Trend, or an Evergreen Classic?


    Find more from Young Goose:

    • Blue Peptide Spray – Cellular hydration meets antioxidant power → Blue Peptide Spray
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    PRP, Red Light & Skincare Myths That Age You Faster Oct 08, 2025
    Show notes

    What if the most popular skin treatments today are quietly accelerating aging beneath the surface?

    In this episode of Biohacking Beauty, we go unfiltered, sharing the procedures we actually trust, the ones we avoid, and the rules we’re not afraid to break.

    We explain why microneedling with PRP remains the gold standard for regeneration, why red light therapy is the ultimate mitochondria hack, and how pairing it with our Ladder Serum doubles the results. We also reveal why your skin’s metabolic state, NAD+ levels, senescence, and mitochondrial function determine how well any treatment works.

    Along the way, we cut through Instagram hype, debunk outdated myths, and reveal what actually holds up to real skin biology. You don’t want to miss this one.

    We Also Discuss:

    Why Most Skincare Hacks Fail at the Cellular Level

    The Hidden Damage Behind “Hot” Procedures

    Rules We Break for Better Skin

    Face Taping vs. Botox and Other Surprises

    The Skincare Habits That Age You Faster

    Ingredients That Don’t Deserve the Hype

    The Molecules That Could Redefine Skin Longevity

    Where Most People Waste Their Skincare Budget

    eBook Mentioned in This Episode: The Longevity Skin Protocol: Biohacking Your Way to Age Reversal

    Find more from Young Goose:

    • The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body Cream
    • Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serum
    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


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