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    Alternative Health

    Biohacking Beauty: The Anti-Aging Skincare Podcast

    Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond “single-molecule” trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ.

    We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.

    Advertise

    Copyright: © Copyright 2026 Young Goose

    • Apple Podcasts
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    Latest Episodes:
    Dr. Cameron Chesnut: THIS is Why Most Plastic Surgery Goes Wrong… Feb 05, 2025
    Show notes

    Many of us think of plastic surgery as a drastic, last-resort solution, but what if the secret to natural, long-lasting results isn’t about doing more, but doing less? The field of facial rejuvenation has evolved dramatically, moving away from overly invasive procedures and toward minimally invasive, high-impact techniques that enhance both appearance and skin health.

    In this episode of Biohacking Beauty, I sit down with Dr. Cameron Chesnut, a pioneer in holistic plastic surgery, to discuss how strategic, small interventions can create incredible, natural-looking results. Dr. Chesnut explains why traditional plastic surgery approaches are outdated, how perception drift is distorting beauty standards, and the biggest mistakes people make with fillers and cosmetic procedures.

    This is a conversation I’ve been wanting to have for a long time because there’s so much misinformation around cosmetic treatments, skin aging, and longevity. We also dive into cutting-edge recovery techniques, including peptides, hyperbaric oxygen therapy, and regenerative medicine, and how these tools are revolutionizing post-surgical healing and long-term results.

    Dr. Cameron Chesnut is a board-certified dermatologist and facial cosmetic surgeon known for his minimally invasive, high-tech approach to plastic surgery. With a background in biohacking, regenerative medicine, and longevity science, he helps patients achieve natural, long-lasting results while prioritizing overall health and well-being.

    We Also Discuss:

    (00:02) Innovations in Biohacking Plastic Surgery

    (09:47) Strategies for Longevity and Anti-Aging

    (18:02) Biostimulatory Fillers' Impacts on Facial Symmetry

    (24:05) Pre-Surgical Peptides and Recovery Optimization

    (31:09) Regenerative Medicine for Enhanced Recovery

    (40:32) Future Trends in Plastic Surgery

    (46:53) Future of Minimally Invasive Plastic Surgery

    (53:00) Holistic Health Strategies for Youthfulness

    (01:06:18) Specialties in Facial Plastic Surgery

    Learn more about Young Goose:


    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/

    Instagram: @young_goose_skincare


    Learn more about Dr. Cameron Chesnut:


    Instagram: https://www.instagram.com/chesnut.md/

    Website: https://www.clinic5c.com/


    Resources:


    Spermidine research: https://www.longevitybioresearch.org/

    Spermidine in health and disease: https://www.science.org/doi/10.1126/science.aan2788


    Jamie McGuire: Leaky Skin Debunked: What’s Really Happening Jan 31, 2025
    Show notes

    Have you ever stopped to think about the invisible forces that are silently aging your skin—and how the right tools can reverse the damage? In this episode of Biohacking Beauty, I’m diving into a fascinating conversation with Jamie McGuire, a skincare expert and passionate advocate for long-term skin health.

    We explored the often-overlooked role of the skin barrier in maintaining youthful, healthy skin and why NAD, the molecule of cellular repair, is a game-changer. From breaking down what “leaky skin” really means to revealing how inflammation and environmental stressors disrupt your skin’s ability to heal, this episode is packed with essential insights for anyone serious about biohacking their skincare.

    Jamie McGuire is a leading skincare consultant and founder of a wellness platform specializing in customized regimens and holistic health. With over 15 years of experience, she helps clients achieve radiant skin through science-backed solutions. Her expertise and educational approach make her a trusted voice in skincare.

    We Also Discuss:

    00:00 - 07:45 - The Science of NAD: Unlocking Skin Repair and Resilience

    07:45 - 16:20 - Leaky Skin Explained: Repairing Your Barrier for Lasting Results

    16:20 - 23:57 - How Inflammation Sabotages Your Skin—and How to Stop It


    Learn More About


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Learn More About


    Jamie McGuire


    • Website: https://www.jamieanneaesthetics.com/skincare
    • Instagram: https://www.instagram.com/jamieanneaesthetics/


    Melissa Boloña: What’s Really Causing Wrinkles (It’s Not What You Think) Jan 29, 2025
    Show notes

    Many of us chase radiant, youthful skin by investing in expensive products, but I’ve learned that the secret to lasting results often lies beneath the surface—literally. Your gut health plays a pivotal role in your skin’s appearance, influencing everything from hydration to inflammation and even premature aging. The more I dive into this topic, the more I realize how understanding the gut-skin connection is key to unlocking healthier, glowing skin.

    In this episode of Biohacking Beauty, I sit down with Melissa Boloña, founder of The Beauty and the Broth, to discuss how gut health impacts our skin and why bone broth has become a cornerstone of so many wellness routines. Melissa shares her personal journey of overcoming chronic digestive issues and autoimmunity, and we break down the science behind bone broth’s bioavailability, its role in repairing the gut lining, and how it supports collagen production while reducing inflammation.

    This is a conversation I’ve been wanting to have for a long time because the connection between gut health and skin health is often overlooked. We also dive into common misconceptions about collagen supplements, why sourcing and bioavailability matter, and how simple changes to your routine can have a profound impact on your overall health and appearance.

    Melissa Boloña


    is the founder of The Beauty and the Broth, a wellness brand redefining bone broth with convenience and quality. After overcoming chronic digestive issues and autoimmunity, she became passionate about the gut-skin connection and ancestral nutrition.

    Let's dive in!


    We Also Discuss:

    (00:01) The Power of Bone Broth

    (08:50) Discovering the Benefits of Bone Broth

    (20:30) Exploring Bone Broth Sourcing and Benefits

    (29:57) Exploring Nutrition & Lifestyle Choices

    (35:15) Balancing Business and Wellness Priorities

    (50:22) Navigating Brand Integrity and Decision-Making


    Learn more about:


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare

    Melissa Boloña


    • Website: https://thebeautyandthebroth.com
    • Instagram: https://www.instagram.com/melissabolona


    Dr. Nasha Winters: Is Your 'Healthy' Lifestyle Damaging Your Skin? Jan 22, 2025
    Show notes

    We all want to live longer, healthier lives—but what if the key to longevity isn’t just about doing more, but understanding how your body adapts to stress? From navigating everyday challenges to the science of hormesis, the small, intentional stressors we introduce can either build resilience or break us down.

    In this episode of Biohacking Beauty, I sit down with Dr. Nasha Winters, a pioneer in metabolic oncology and someone I’ve admired for years, to unpack the real story behind resilience and how it ties into beauty, health, and longevity. We dive into how your body’s response to stress—whether it’s from your environment, your relationships, or even your skincare routine—can impact everything from mitochondrial health to cellular repair.

    We also get real about why your sense of purpose isn’t just motivational fluff—it’s a biological powerhouse that can extend your life. Plus, we discuss how building community and avoiding isolation might just be the ultimate biohack.

    Dr. Nasha Winters has over 30 years of experience in metabolic health and mitochondrial optimization. Her work isn’t just about preventing disease—it’s about living with purpose, vitality, and strength.

    This conversation will open your eyes to how the small, everyday choices you make can completely shift your health trajectory. Let’s dive in!

    We Also Discuss:

    (00:01) Biohacking and Integrative Medicine Discussion

    (12:49) Harnessing Hormesis for Health and Wellness

    (26:54) Mindful Practices and Stress Response

    (37:37) Navigating Health and Wellness Journey

    (51:05) Embracing Evolution and Purpose in Wellness

    (01:08:00) Gratitude and Excitement for Reunion

    Learn more about:

    Young Goose

    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Dr. Nasha Winters


    • Website: https://www.drnasha.com/
    • Instagram: https://www.instagram.com/drnashawinters/


    Exfoliation Explained: The Science Behind Smooth Skin Jan 17, 2025
    Show notes

    Most of us have heard of exfoliation, and you may already be incorporating this step into your routine. But did you know that exfoliation plays a pivotal role in keeping your skin radiant and healthy? Think of exfoliation as prepping a canvas before painting. Just like you wouldn't apply fresh paint on a wall without preparing it first, you shouldn't apply skincare products on a layer of dead skin cells.

    Welcome to another episode of the Biohacking Beauty podcast brought to you by Young Goose Skincare! In this episode, host Amitay Eshel, the CEO of Young Goose, dives into an essential step in your skincare routine: exfoliation. He covers why exfoliation is crucial for maintaining healthy skin, and the difference between chemical and mechanical exfoliation. Plus, he shares the importance of understanding the needs of your skin.

    What we discuss:

    [00:02:25] Why skin cell turnover is crucial for maintaining healthy skin

    [00:03:15] Chemical vs. mechanical exfoliation

    [00:04:08] The benefits of proper exfoliation

    [00:08:22] Why understanding the needs of your skin is essential

    Key Takeaways:

    • Exfoliation plays an important role in enhancing the absorption and effectiveness of skincare products. By removing the layer of dead skin cells on the surface of your skin, exfoliation allows the active ingredients in skincare products to penetrate more deeply and work more effectively. This means that your moisturizers, serums, and treatments can better target and address specific skin concerns, resulting in improved overall skincare results.
    • There are two primary types of exfoliation: mechanical and chemical. Mechanical or physical exfoliation entails physically scrubbing the skin using an abrasive substance. In contrast, chemical exfoliation involves using ingredients such as acids or enzymes that dissolve the glue binding the dead skin cells together.
    • Understanding the specific requirements of your skin is vital for effective exfoliation. Oily skin, for instance, often faces issues like excessive dead skin cells and clogged pores. Frequent exfoliation can be beneficial in maintaining a clearer complexion for oily skin types. On the other hand, dry skin may require a gentler approach to exfoliation, as it tends to be more sensitive.

    Learn More about Young Goose:

    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Dr. Mary Alice Mina: Are You Using Too Many Skincare Products? Stop Overthinking Skincare and Do This Instead Jan 15, 2025
    Show notes

    Many of us unknowingly harm our skin with habits we think are helpful. Over-exfoliating, using the wrong products, or skipping sunscreen altogether can damage your skin barrier, leading to dryness, sensitivity, and even premature aging. If your skincare routine feels overwhelming—or worse, ineffective—it might be time to simplify and get back to the basics.

    In this episode of Biohacking Beauty, I sat down with Dr. Mary Alice, a dermatologist with nearly two decades of experience, to dive into how to avoid these common mistakes. We talked about the power of skin minimalism, why your skin barrier is your first line of defense, and how understanding your skin’s unique needs can help you achieve real, long-lasting results.

    We also shared practical advice on building a streamlined routine that works and why less is often more when it comes to skincare. If you’re tired of wasting time and money on products that don’t deliver, this episode is for you.

    Dr. Mary Alice Mina is a procedural dermatologist specializing in skin health and longevity. Over the past two decades, she has helped countless patients transform their skin by focusing on evidence-based treatments and personalized care.

    This conversation will leave you inspired to rethink your routine. Don’t miss it!

    We Also Discuss:

    (00:00) Skin Health and Biohacking Tips

    (17:53) Navigating Skincare Marketing Myths

    (25:00) The Truth About Natural Skincare

    (36:42) The Challenge of Misinformation in Skincare

    (43:51) Menopausal Skin Care Needs

    Learn more about:


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Mary Alice Mina


    • Website: https://www.theskinreal.com
    • Instagram: https://www.instagram.com/drminaskin/


    Paul Sorbo: Performance vs Longevity: Are You Sacrificing One? Jan 08, 2025
    Show notes

    Do you ever feel like your busy life keeps sabotaging your health and skincare goals? Whether it’s travel, work stress, or just too many options to choose from, these roadblocks can leave you stuck and overwhelmed. But what if there was a way to cut through the noise and build routines that work—anytime, anywhere?

    In this episode of Biohacking Beauty, I sit down with Paul Sorbo, an entrepreneur who has spent years revolutionizing the wellness industry, to uncover how to simplify the approach to health and skincare. We dive into the real issue of decision fatigue—why having too many choices leaves you paralyzed—and how to navigate it with smarter systems.

    Paul also shares the inspiration behind his innovative Travel Younger kit—a game-changing approach to staying on track even with a hectic schedule. We discuss the importance of consistency over perfection, the challenges of scaling science-backed products without compromising quality, and why building a healthy lifestyle should feel effortless, not overwhelming.

    This conversation is packed with insights for anyone looking to strike the balance between a busy life and optimal health. From finding needle-moving products to developing routines that stick, this episode will leave you inspired to take control of your health and skincare journey.

    Paul Sorbo is a wellness entrepreneur with over a decade of experience in health optimization. Known for his science-driven mindset, Paul has created innovative solutions like Hop and Morning Routine, blending cutting-edge research with real-world accessibility. His expertise lies in making wellness practical, scalable, and sustainable for people with fast-paced lives.

    We Also Discuss:

    (00:00) Exploring Longevity and Wellness Journeys

    (14:55) Navigating Longevity & Wellness Trends

    (27:08) Empowering Women in Wellness Industry

    (40:33) Travel Younger Campaign Planning and Implementation

    (52:48) Fatherhood Announcement and Appreciation

    Learn more about:

    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare



    Learn more about:


    Paul Sorbo

    Website: gomixtech.com

    Instagram: https://www.instagram.com/pjsorbo/?hl=en


    Nerida Joy: The Small Skincare Habits That Will Transform Your Skin Jan 01, 2025
    Show notes

    What if your skincare routine is missing the key to truly transforming your skin—inside and out?

    In this episode of Biohacking Beauty, I invite you into the often-overlooked fundamentals of skin health and longevity. From avoiding the biggest mistakes in skincare to unlocking the power of ingredients like flavonoids and perfecting your routine, this conversation is packed with actionable insights to elevate your approach to skin wellness.

    I’m joined by Nerida Joy, one of the most experienced professionals in the skincare world. Together, we uncover why proper cleansing is 50% of your regimen, the dangers of overusing aggressive treatments and devices, and how diet, stress, and movement play a surprising role in how your skin behaves.

    You’ll also learn practical ways to assess your skin type at home, spot sub-conditions that need addressing, and build a routine that works for your unique skin needs—without the hype or shortcuts.

    Nerida Joy is a world-renowned esthetician with over 46 years of expertise in skin biology and clinical rejuvenation. Known for her evidence-based approach and holistic techniques, she specializes in optimizing skin health at a cellular level.

    We Also Discuss:

    (00:03) Biohacking Beauty With Skincare Expert Nerida Joy

    (09:15) Understanding Skin Types and Sub-Conditions

    (17:56) Essential Hydration for Healthy Skin

    (29:19) Why Healthy Skin Must Come Before Treatments

    (36:50) The Hidden Dangers of Overusing Skincare Devices

    Learn more about:


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Nerida Joy:


    Website: https://neridajoy.com/

    Instagram: https://www.instagram.com/askneridajoy


    AI in Skincare: Revolution or Overhype? Dec 27, 2024
    Show notes

    Could artificial intelligence revolutionize personalized healthcare and skincare—or is its potential being overstated?

    I had the incredible opportunity to join Stephanie on her Change Life Destiny Podcast to discuss one of the most fascinating topics in healthcare today: the role of AI in shaping the future of personalized health and skincare.

    In our conversation, we explored how AI is being utilized to diagnose conditions, develop smarter skincare solutions, and even redefine how practitioners and patients approach health optimization. But here’s the twist—AI, as powerful as it is, can’t replace human expertise. I shared my perspective on why the balance between cutting-edge technology and practitioner insight is critical for creating strategies that truly work.

    We also touched on the concept of 'prejuvenation,' a proactive approach to enhancing recovery and skin rejuvenation, and shared real-life success stories that demonstrate the remarkable synergy between innovation and expertise.

    This episode is packed with actionable insights and forward-thinking ideas for anyone interested in biohacking, longevity, and achieving optimal skin health.

    We Also Discuss:

    15:52 - 17:19 – The Role of AI in Healthcare: Revolutionizing or Replacing Professionals?

    17:19 - 18:25 – Why Human Expertise Is Essential in the Age of AI

    18:25 - 20:46 – How Young Goose Leverages AI to Empower Practitioners and Patients

    20:46 - 23:35 – Real-World Case Studies: Skin Transformation with AI-Informed Strategies

    23:35 - 25:22 – Introducing ‘Prejuvenation’: Preparing Skin for Optimal Recovery and Results

    Learn More About


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare



    Learn More About Stephanie and The Change Life Destiny Show


    • Website: https://www.changelifedestiny.com/

    Instagram: https://www.instagram.com/changinglifedestiny/


    Stephanie Gray: Your Skin and Hormones Are Talking—Are You Listening? Dec 25, 2024
    Show notes

    What if your skin holds the ultimate key to your overall longevity? Many of us focus on treating the body while overlooking how skin health directly impacts whole-body aging. From senescent cells wreaking havoc to innovative NAD therapies, there's a science to reversing skin aging and unlocking vitality.

    We dive into these fascinating topics in this episode of Biohacking Beauty with guest Dr. Stephanie Gray. Together, we unpack how environmental factors drive 80% of skin aging, the revolutionary role of NAD+ in DNA repair, and how innovative skincare formulations protect against modern-day stressors like EMFs and pollution.

    Dr. Stephanie Gray is a functional medicine practitioner, hormone health expert, and founder of the Integrative Health and Hormone Clinic. With a focus on bioidentical hormone replacement and anti-aging strategies, she has dedicated her career to helping patients balance their hormones, enhance their vitality, and live with purpose.

    We Also Discuss:

    (00:02) Biohacking Beauty and Skin Health

    (08:09) Skin and Whole Body Aging

    (24:52) Skin Barrier Repair and Anti-Aging

    (39:24) Advanced Skincare Regimen and Product Usage

    (55:06) Skincare Regimen and Product Protocol

    (01:07:38) Temperature Modulation for Health and Longevity

    Learn more about:


    Young Goose


    • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
    • Instagram: @young_goose_skincare


    Learn more about Stephanie Gray:


    Website: https://ihhclinic.com/

    Instagram: https://www.instagram.com/stephaniegraydnp/


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