VJOncology Podcast

Latest Episodes:

iwCAR-T sessions: clinical advances in GI Cancers Aug 07, 2024

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In this podcast, we join leading experts Randy Hecht from UCLA, Diane Simeone from University of California San Diego, and Ben Schechter from Dana-Farber Cancer Institute as they delve into groundbreaking advancements in GI cancer therapies, as presented at the latest iwCAR-T workshop in Miami, Florida.

Explore the latest updates and insights on translational research in pancreatic cancer, including innovative biopsy techniques and the evolving role of immuno-oncology in treating solid tumors. Discover the potential of new cell therapies like TAC T-cells and the promising Claudin 18.2-targeted therapies, highlighting their efficacy and safety profiles. These discussions underscore the need for continued research in precision oncology and the adaptation of hematologic malignancy successes to solid tumors.

The post iwCAR-T sessions: clinical advances in GI Cancers appeared first on VJOncology.

iwCAR-T sessions: cell therapies for melanoma and sarcomas Jul 26, 2024

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In this week’s podcast, we join experts Allison Betof Warner from Stanford Medicine, Amod Sarnaik from Moffitt Cancer Center, and Elizabeth Loggers from Fred Hutchinson Cancer Center on transformative innovations in cell therapies for melanoma and sarcomas, as presented at the most recent iwCAR-T workshop in Miami, Florida.

Discover the latest updates and perspectives on advanced TIL therapies, including their promising progression-free survival results and new protocols for melanoma-induced brain metastases, along with updates on TCR-based therapies for synovial sarcoma. These developments underscore the need for continued research in adjuvant treatment settings and tumor immunology.

The post iwCAR-T sessions: cell therapies for melanoma and sarcomas appeared first on VJOncology.

iwCAR-T sessions: Advances in breast and gynecological cancers Jul 19, 2024

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In this week’s episode, we join Jennifer Specht from Fred Hutchinson Cancer Center, Saurabh Garg from Moffitt Cancer Center, and Rizwan Romee from Dana-Farber Cancer Institute on pioneering advancements in CAR-T cell therapies for breast and gynecological cancers, as discussed at the recent 6^th annual iwCAR-T workshop in Miami, Florida.

Tune in to learn about the fascinating evolution of ROR1-targeting CAR-T cells for triple negative breast cancer, NK-cell targeting CAR-T therapeutics in ovarian cancer, and combinatorial therapy using dendritic cells against HER2-positive breast cancer. As their development progresses, several challenges and advantages come to light.

The post iwCAR-T sessions: Advances in breast and gynecological cancers appeared first on VJOncology.

iwCAR-T sessions: clinical advances in lung cancer Jul 12, 2024

Show notes

Welcome to another episode of VJOncology! In this episode, we dive into cutting-edge CAR-T cell therapies for the management of lung cancers, discussed at the sixth International Workshop on CAR-T in Miami, Florida.

Join Julian Molina from the Mayo Clinic, Ben Creelan from Moffitt Cancer Center, and Adam Schoenfeld from Memorial Sloan Kettering Cancer Center as they explore innovative CAR-T strategies and their applications in thoracic oncology. They address the challenges of integrating cell therapies in clinical practice, the potential for tumor cell banking, and the implications of tumor microenvironment modulation.

Discover insights into the latest developments in claudin-targeting CAR-T cells for non-small cell lung cancer and the exciting prospects of DLL3-targeting therapies for neuroendocrine tumors. This episode provides a comprehensive overview of the future landscape of cell therapy in lung cancer treatment.

Don’t miss this enlightening discussion! Subscribe and leave a review on your favorite podcast app. Follow us on Twitter at VJOncology and visit vjoncology.com for more content from the International Workshop on CAR-T.

The post iwCAR-T sessions: clinical advances in lung cancer appeared first on VJOncology.

Highlights in colorectal cancer at ASCO and ESMO GI 2024 Jul 05, 2024

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In this week’s podcast, we will discuss the most recent developments in colorectal cancer from the 2024 ASCO and ESMO Gastrointestinal (GI) Annual Meetings held in Chicago, IL and Munich, Germany respectively. Join us as five renowned experts discuss highly anticipated findings from clinical trials across different colorectal cancer subtypes.

Heinz-Josef Lenz from the University of Southern California first comments on the expanded efficacy analysis from the Phase III CheckMate 8HW study in MSI-H/dMMR metastatic colorectal cancer and Sara Lonardi from the Veneto Institute of Oncology in Padua, Italy, discusses the health-related quality of life outcomes from the trial. John Strickler from Duke University then provides 32 month follow-up data from the MOUNTAINEER trial of tucatinib and trastuzumab in HER2+ colorectal cancer. Additionally, listen to insightful perspectives from Major Lee, The University of Pennsylvania, and David Tougeron, Poitiers University Hospital, on practice changing trials in colorectal cancer.

The post Highlights in colorectal cancer at ASCO and ESMO GI 2024 appeared first on VJOncology.

Skin Cancer Highlights at ASCO 2024 Jun 24, 2024

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Welcome to another episode of VJ Oncology Podcasts! Today, we spotlight key advances in skin cancer research shared at ASCO 2024. Join us as six leading experts reveal groundbreaking findings from recent clinical trials.

First, Georgina Long from the University of Sydney discusses the NADINA trial, a landmark Phase III study on neoadjuvant immunotherapy for melanoma. Next, Omid Hamid from The Angeles Clinic presents early results from a Phase I trial of IMC-F106C in metastatic cutaneous melanoma. Hear insights from Meredith McKean, Sapna Patel, Joseph J. Sacco, and Rodabe Amaria on innovative therapies and trial results shaping the future of skin cancer treatment. Tune in for these and more exciting updates!

The post Skin Cancer Highlights at ASCO 2024 appeared first on VJOncology.

iwCAR-T sessions: Clinical Advances in Head and Neck Cancer and Brain Tumors Jun 07, 2024

Show notes

Welcome to another episode of VJ Oncology! In this episode, we delve into pioneering CAR-T strategies for head and neck cancers and brain tumors, as discussed at the recent iwCAR-T workshop in Miami, Florida.

Join Kedar Khartani from Moffitt Cancer Center and Susanna Baumeister from Dana-Farber Cancer Institute as they explore groundbreaking CAR-T approaches and clinical trials targeting glioblastoma and neuroblastoma. They address the challenges and future prospects of commercializing these therapies, particularly for rare and pediatric cancers.

Discover the exciting developments in ALK-targeting CAR-T cells for neuroblastoma and new antigen-selected TIL therapies for head and neck cancers. This episode offers valuable insights into the evolving landscape of cell therapy in oncology.

Don’t miss this informative discussion! Subscribe and leave a review on your favorite podcast app. Follow us on Twitter at VJ Oncology and visit vjoncology.com for more content from the iwCAR-T workshop.

The post iwCAR-T sessions: Clinical Advances in Head and Neck Cancer and Brain Tumors appeared first on VJOncology.

ELCC 2024 Highlights May 24, 2024

Show notes

This week, we bring you key highlights from European Lung Cancer Congress (ELCC) 2024, which took place in Prague, Czech Republic, including the EVOKE-02, IMscin002, FLAURA2, MARIPOSA-2 and PAPILLON clinical trials. Hear from Federico Cappuzzo, AUSL della Romagna-Ravenna, Ravenna, Italy, Natalia Valdiviezo, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru, Alexander Spira, Next Oncology-Virginia VCS, Joshua Sabari, NYU Langone Health, New York, NY, as they talk on exciting results in lung cancer.

The post ELCC 2024 Highlights appeared first on VJOncology.

Key Updates at ESMO Breast 2024 May 17, 2024

Show notes

In today’s episode, we bring you key highlights from ESMO Breast 2024, diving into important discussions surrounding the latest research and clinical data regarding breast cancer. We bring insights from top field experts, set to enlighten you on new breakthroughs and developments, including updates from the DESTINY-Breast02 trial as well as first-line CDK4/6 inhibitor clinical data in HR+/HER2-advanced breast cancer.

The post Key Updates at ESMO Breast 2024 appeared first on VJOncology.

Bladder Cancer Awareness Month Part II: Management of UC in the UK May 10, 2024

Show notes

In this podcast, we continue to commemorate Bladder Cancer Awareness Month in May with a special limited series, where we invite a special guest to discuss and share their expert perspectives within this ever evolving field. This week, Rob Jones, MD, PhD, University of Glasgow, Glasgow, UK, will be talking about first-line treatment paradigms in bladder cancer, survivorship challenges, and the current state of bladder cancer treatment in the UK.

The post Bladder Cancer Awareness Month Part II: Management of UC in the UK appeared first on VJOncology.

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