The Incubator

Latest Episodes:

#021 - Journal Club - When to trach?, digital tracheal intubation, rapid vs slow feed increase, female blood-donor = better, and more! Sep 19, 2021

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04:10 - Qualitative indications for tracheostomy and chronic mechanical ventilation in patients with severe bronchopulmonary dysplasia. https://www.nature.com/articles/s41372-021-01165-9

15:40 - Association between Term Equivalent Brain MRI and 2 Year Outcomes in Extremely Preterm Infants: A Report from the PENUT Trial Cohort. https://jpeds.com/retrieve/pii/S0022347621008258

22:46 - Association of Blood Donor Sex and Age With Outcomes in Very Low-Birth-Weight Infants Receiving Blood Transfusion. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783715

29:30 - Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001241.pub8

38:29 - Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial. https://www.nature.com/articles/s41372-021-01018-5.

41:20 - Adverse Events and Associated Factors During Intra-hospital Transport of Newborn Infants. https://www.jpeds.com/article/S0022-3476(21)00859-3/fulltext

46:17 - Digital tracheal intubation and finger palpation to confirm endotracheal tube tip position in neonates: A systematic review and meta‐analysis. https://onlinelibrary.wiley.com/doi/10.1002/ppul.25551

52:41 - The DELUX study: development of lung volumes during extubation of preterm infants. https://www.nature.com/articles/s41390-021-01699-w

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As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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#020 - Dr. Erik Jensen - Bronchopulmonary dysplasia research Sep 12, 2021

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Dr. Erik Jensen is an attending neonatologist in the division of neonatology at the Children's hospital of Philadelphia. He is an assistant professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

Dr. Jensen’s research seeks to improve the long-term respiratory health of premature infants through: (1) clinical and translational studies that aim to develop evidence-based strategies to prevent and treat BPD; (2) novel characterization of disease severity and phenotypes in BPD; and (3) application of health services research techniques to investigate the association between hospital-level factors and neonatal morbidity and mortality.

Dr. Jensen’s research is supported by grant funding from the National Heart Lung and Blood Institute (NHLBI), the National Institute of Child Health and Human Development (NICHD), and the American Lung Association (ALA). He is a member of the International BPD Collaborative pharmacology working group and the International Neonatal Consortium (INC) BPD working group. He has received multiple clinical and research awards.

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#019 - Journal Club - Do we even need car seat tests?, COVID19: Pregnancy/Neonatal outcomes, Breast milk and cardiac function at 1yr, Noise level inside incubators... and more! Sep 05, 2021

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Please find the list of articles discussed in this week’s journal club with links to the full text.

03:15 - Characteristics and Outcomes of Women With COVID-19 Giving Birth at US Academic Centers During the COVID-19 Pandemic. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2782978

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2779182

18:15 - Timing of neonatal stoma closure: a survey of health professional perspectives and current practice. https://fn.bmj.com/content/early/2021/08/18/archdischild-2021-322040

28:12 - Newborn Incubators Do Not Protect from High Noise Levels in the Neonatal Intensive Care Unit and Are Relevant Noise Sources by Themselves. https://www.mdpi.com/2227-9067/8/8/704

38:23 - Cardiac Performance in the First Year of Age Among Preterm Infants Fed Maternal Breast Milk. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783546

45:55 - Race, language, and neighborhood predict high-risk preterm Infant Follow Up Program participation. https://www.nature.com/articles/s41372-021-01188-2

53:30 - Is late treatment with acetaminophen safe and effective in avoiding surgical ligation among extremely preterm neonates with persistent patent ductus arteriosus? https://www.nature.com/articles/s41372-021-01194-4

59:59 - Is it time to study routine car seat tolerance screening in a randomized controlled trial? An international survey of current practice and clinician equipoise. https://www.nature.com/articles/s41372-021-01167-7

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#018 - Dr. Diana Montoya-Williams - Health equity research in neonatology Aug 29, 2021

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Dr. Diana Montoya-Williams is an attending neonatologist in the division of Neonatology at Children’s Hospital of Philadelphia, a clinician scientist in CHOP’s PolicyLab and an assistant professor of Pediatrics in the University of Pennsylvania’s Perelman School of Medicine. She graduated from Harvard College with a degree in the History of Science and received her medical degree from Columbia University. Subsequently, she completed her residency in Pediatrics and her fellowship in Neonatology at the University of Florida. She conducts research on the drivers of racial and ethnic inequities in infant health outcomes. Her recent work has also explored structural and individual factors that confer resilience to poor birth and infant health outcomes among populations vulnerable to discrimination. Dr. Montoya-Williams has a special interest in immigration policies as political determinants of Latinx health outcomes. As a member of CHOP PolicyLab’s Health Equity team, she also engages in legislative and policy advocacy.
Dr. Montoya-Williams can be contacted by email: MONTOYAWID@chop.edu
or via twitter: @DrDianaMW
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As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.

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#017 - Journal Club - The DO NOT cool for HIE paper, Autism & prematurity, NRP vs PALS, NEC vs SIP management ... and more Aug 22, 2021

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Please find the list of articles discussed in this week’s journal club with links to the full text.

01:36 - Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00264-3/fulltext

16:48 - Preterm or Early Term Birth and Risk of Autism. https://pediatrics.aappublications.org/content/early/2021/08/10/peds.2020-032300

25:40 - Neonatal resuscitation in the NICU; Challenges beyond NRP. https://onlinelibrary.wiley.com/doi/10.1111/apa.16057

31:15 - Improving Compliance with a Rounding Checklist through Low- and High-technology Interventions: A Quality Improvement Initiative. https://journals.lww.com/pqs/Fulltext/2021/07000/Improving_Compliance_with_a_Rounding_Checklist.21.aspx

38:59 - Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial. https://journals.lww.com/annalsofsurgery/Abstract/9000/Initial_Laparotomy_Versus_Peritoneal_Drainage_in.93407.aspx

51:27 - Automated Explainable Multidimensional Deep Learning Platform of Retinal Images for Retinopathy of Prematurity Screening. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2779454

54:00 - Neonatal mortality prediction with routinely collected data: a machine learning approach. https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-021-02788-9

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#016 - Dr. Brodsky & Dr. Martin - Authors of Neonatology Review Aug 15, 2021

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Dr. Brodsky and Dr. Martin are the authors of the renowned books titled Neonatology Review. This series, well known to every neonatal trainee, is currently in its third edition. They have also published other books including Neonatology Review Images and Neonatology Review: Questions & Answers.
Dr. Dara Brodsky is an Associate Professor at Harvard Medical School. She is the Director of Education for the department of Neonatology at Beth Israel Deaconess Medial Center. She is also the Editor-in-Chief of NeoReviews.
Dr. Camilia R. Martin is an Associate Professor of Pediatrics at Harvard Medical School, and the Associate Director of the Neonatal Intensive Care Unit and Director for Cross-Disciplinary Research Partnerships in the Division of Translational Research at Beth Israel Deaconess Medical Center Boston, MA.
You can in touch with them by email at:
Dr. Brodsky: dbrodsky@bidmc.harvard.edu
Dr. Martin: cmartin1@bidmc.harvard.edu
Their books can be purchased at the following website:
https://www.lulu.com/spotlight/neonatologyreview/
______________________________________________________________________________________________________
As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!

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#015 - Journal Club - Hydrocortisone and neurodevelopment, Precedex post-op, frequency of spontaneous PDA closure after discharge, high-dose caffeine, and more... Aug 08, 2021

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As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!
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Please find the titles and links to the articles mentioned in this week's journal club and timestamps for your convenience:
02:30 - Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years’ Corrected Age: Follow-up of a Randomized Clinical Trial. https://jamanetwork.com/journals/jama/article-abstract/2782313
07:50 - Postnatal Corticosteroids to Prevent or Treat Bronchopulmonary Dysplasia. https://www.karger.com/Article/FullText/515950
18:30 - Temporal Trends in Neurodevelopmental Outcomes to 2 Years After Extremely Preterm Birth. https://jamanetwork.com/journals/jamapediatrics/article-abstract/2782149
26:00 - An assessment of dexmedetomidine as an opioid-sparing agent after neonatal open thoracic and abdominal operations. https://www.nature.com/articles/s41372-021-01175-7
32:23 - Association of time of day and extubation success in very low birthweight infants: a multicenter cohort study. https://www.nature.com/articles/s41372-021-01168-6
39:27 - Caffeine citrate for apnea of prematurity—One dose does not fit all a prospective study. https://www.nature.com/articles/s41372-021-01172-w
43:40 - Early High-Dose Caffeine Improves Respiratory Outcomes in Preterm Infants. https://www.mdpi.com/2227-9067/8/6/501
48:35 - Low Rate of Spontaneous Closure in Premature Infants Discharged with a Patent Ductus Arteriosus: A Multicenter Prospective Study. https://jpeds.com/retrieve/pii/S0022347621007022
55:36 - Effects of single family room architecture on parent–infant closeness and family centered care in neonatal environments—a single-center pre–post study. https://www.nature.com/articles/s41372-021-01137-z
60:53 - Asynchronous telemedicine for clinical genetics consultations in the NICU: a single center’s solution. https://www.nature.com/articles/s41372-021-01070-1
64:00 - Cortical hemodynamic activity and pain perception during insertion of feeding tubes in preterm neonates: a randomized controlled cross-over trial. https://www.nature.com/articles/s41372-021-01166-8

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#014 - Dawn Raffel - The incredible story of Martin Couney (Book club episode) Aug 01, 2021

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Dawn Raffel's book: The Strange Case of Dr. Couney was chosen as one of NPR’s best books of 2018 and awarded a 2019 Christopher Award for books that affirm the highest values of the human spirit.
As Dawn Raffel recounts, Dr. Couney used incubators and careful nursing to keep previously doomed infants alive, while displaying these babies alongside sword swallowers, bearded ladies, and burlesque shows at Coney Island, Atlantic City, and venues across the nation. How this turn-of-the-twentieth-century émigré became the savior to families with premature infants—known then as “weaklings”—as he ignored the scorn of the medical establishment and fought the rising popularity of eugenics is one of the most astounding stories of modern medicine. Dr. Couney, for all his entrepreneurial gusto, is a surprisingly appealing character, someone who genuinely cared for the well-being of his tiny patients.
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As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

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#013 - Journal Club - Clonidine and NAS, aerosolized surfactant, Following baby back home, and more... Jul 25, 2021

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01:50 - Reviewing recordings of neonatal resuscitation with parents. https://fn.bmj.com/content/106/4/346

10:55 - Associations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS https://fn.bmj.com/content/106/4/392

19:28 - A Retrospective Review Following the Addition of Clonidine to a Neonatal Abstinence Syndrome Treatment Algorithm. https://www.frontiersin.org/articles/10.3389/fped.2021.632836/full

25:03 - Trial of aerosolised surfactant for preterm infants with respiratory distress syndrome. https://fn.bmj.com/content/early/2021/06/09/archdischild-2021-321645

30:15 - Interface leakage during neonatal CPAP treatment: a randomised, cross-over trial. https://fn.bmj.com/content/early/2021/06/28/archdischild-2021-321579

33:55 - Changes in Physicians' Perceptions and Practices on Neonatal Pain Management Over the Past 20 Years. A Survey Conducted at Two Time-Points. https://www.frontiersin.org/articles/10.3389/fped.2021.667806/full

39:02 - The Experience of Housing Needs Among Families Caring for Children With Medical Complexity. https://pediatrics.aappublications.org/content/148/1/e2020018937

47:10 - Home Visiting for NICU Graduates: Impacts of Following Baby Back Home. https://pediatrics.aappublications.org/content/148/1/e2020029397

52:25 - An Infant Carrier Intervention and Breastfeeding Duration: A Randomized Controlled Trial. https://pediatrics.aappublications.org/content/148/1/e2020049717

56:37 - Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States. https://pediatrics.aappublications.org/content/148/1/e2020030007

58:41 - Human milk feeding and cognitive outcome in preterm infants: the role of infection and NEC reduction. https://www.nature.com/articles/s41390-021-01367-z

61:27 - Validity of Random Triglyceride Levels in Infants Receiving Parenteral Nutrition. https://www.frontiersin.org/articles/10.3389/fped.2021.601915/full

62:40 - Degree of ventriculomegaly predicts school-aged functional outcomes in preterm infants with intraventricular hemorrhage. https://www.nature.com/articles/s41390-021-01631-2

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#012 - Juliette Lee RN - Adult Premie and Pediatric Nurse Jul 18, 2021

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Juliette Lee is a pediatric nurse from Cambridge in the U.K. She was born extremely preterm in the 1990's and has since worked with other adult preterm to create the adult premie advocacy network (www.adultpreemies.com).
She also took part in a large study of former preterm adults that you can find at the following link: https://pubmed.ncbi.nlm.nih.gov/31732683/
This was undoubtedly a great discussion.
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As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

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