The Incubator

Latest Episodes:

#031 - Dr. Kristyn Beam MD & Dr. Andrew Beam - Artificial intelligence in the neonatal ICU Nov 21, 2021

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Join us this week for a fascinating discussion about artificial intelligence in neonatology with doctors Kristyn and Andrew Beam.
Dr. Kristyn Beam is an attending neonatologist at Beth Israel Deaconess Medical Center in Boston, MA. She is also an Instructor in the Department of Pediatrics at Harvard Medical School. Her research focuses on machine learning applications for neonatal data with a focus on improving our decision-making in the NICU at the point of care and ultimately improving neonatal outcomes.
Dr. Andrew Beam is an assistant professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, with secondary appointments in the Department of Biomedical Informatics at Harvard Medical School and the Department of Newborn Medicine at Brigham and Women’s Hospital. His research develops and applies machine-learning methods to extract meaningful insights from clinical and biological datasets, with a special focus on neonatal medicine.

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As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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#030 - Journal Club - Risk of cancer after phototherapy, neurodevelopment of IUGR babies, COCHRANE review of early steroids for BPD....and more Nov 14, 2021

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As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.

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1:20 - Update on Phototherapy and Childhood Cancer in a Northern California Cohort. https://publications.aap.org/pediatrics/article-abstract/148/5/e2021051033/181342/Update-on-Phototherapy-and-Childhood-Cancer-in-a?redirectedFrom=fulltext

10:55 - Hour-Specific Total Serum Bilirubin Percentiles for Infants Born at 29–35 Weeks’ Gestation. https://www.karger.com/Article/FullText/519496

19:55 - Neurodevelopmental Outcomes following Intrauterine Growth Restriction and Very Preterm Birth. https://www.jpeds.com/article/S0022-3476(21)00667-3/fulltext

29:05 - Enteral Iron Supplementation in Infants Born Extremely Preterm and its Positive Correlation with Neurodevelopment; Post Hoc Analysis of the Preterm Erythropoietin Neuroprotection Trial Randomized Controlled Trial. https://jpeds.com/retrieve/pii/S0022347621006867

40:50 - Caffeine is a respiratory stimulant without effect on sleep in the short-term in late-preterm infants. https://www.nature.com/articles/s41390-021-01794-y

48:06 - Lung Ultrasound for Prediction of Bronchopulmonary Dysplasia in Extreme Preterm Neonates: A Prospective Diagnostic Cohort Study. https://jpeds.com/retrieve/pii/S0022347621006612

53:45 - Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001146.pub6/full

61:14 - A novel and accurate method for estimating umbilical arterial and venous catheter insertion length. https://www.nature.com/articles/s41372-021-01121-7

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#029 - Keliana O’Mara, PharmD - Pharmacists in the NICU, opportunities and challenges. Nov 07, 2021

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Keliana O’Mara, PharmD, is a Pharmacist and the Neonatal Intensive Care Unit Pharmacy Specialist at WakeMed Health and Hospitals. Keliana is a graduate of UNC Eshelman School of Pharmacy. She completed her PGY1 at Moses Cone Health System and a neonatal pharmacotherapy research fellowship at Women’s Hospital of Greensboro. Her areas of research interest include neonatal pain and sedation management, dosing accuracy of medication delivery devices in neonates and pediatrics, neurodevelopmental impact of medication use in neonates, and individualized pharmacokinetic/pharmacodynamics dosing in neonates.

You can reach out to Keliana for collaboration and questions at:
keliana.omara@gmail.com
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#028 - Journal Club - Neonatal Covid, Teaching foreign languages to babies, HIE seizures during rewarming, and more.... Oct 31, 2021

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04:00 - Neonatal MIS-C: Managing the Cytokine Storm. https://pediatrics.aappublications.org/content/early/2021/10/19/peds.2020-042093

17:33 - Randomized clinical trial investigating the effect of consistent, developmentally-appropriate, and evidence-based multisensory exposures in the NICU. https://www.nature.com/articles/s41372-021-01078-7

29:29 - Association of Increased Seizures During Rewarming With Abnormal Neurodevelopmental Outcomes at 2-Year Follow-up. https://jamanetwork.com/journals/jamaneurology/fullarticle/2784930

37:20 - Randomized Trial to Increase Speech Sound Differentiation in Infants Born Preterm. https://jpeds.com/retrieve/pii/S0022347621010283

46:36 - Language function following preterm birth: prediction using machine learning. https://www.nature.com/articles/s41390-021-01779-x

48:45 - The bacterial gut microbiome of probiotic-treated very-preterm infants: changes from admission to discharge. https://www.nature.com/articles/s41390-021-01738-6

56:30 - Prioritization framework for improving the value of care for very low birth weight and very preterm infants. https://www.nature.com/articles/s41372-021-01114-6

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#027 - Dr. Benjamin Rattray - On the impact of stories from the NICU Oct 24, 2021

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Dr. Benjamin Rattray is a newborn critical care physician in North Carolina where he serves as Associate Medical Director of Neonatal Intensive Care at the Cone Health Women’s and Children’s Center. He completed a pediatric residency and a neonatal-perinatal medicine fellowship at Duke University Medical Center, holds an MBA from LSU Shreveport, and is a Certified Physician Executive. He lives with his wife, three children, and a Golden Retriever in Greensboro, North Carolina.
He is the author of the book WHEN ALL BECOMES NEW: A DOCTOR'S STORIES OF LIFE, LOVE, AND LOSS.

Learn more at benjaminrattray.com.

Purchase Dr. Rattray's book on amazon @ https://amzn.to/3juLpfv
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This podcast is proudly sponsored by Chiesi.

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#026 - Journal Club - Detecting bacteremia earlier, viral infections in BPD babies, quality of life for adult premies.... and more Oct 17, 2021

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02:12 - Health-Related Quality of Life from Adolescence to Adulthood Following Extremely Preterm Birth. https://www.jpeds.com/article/S0022-3476(21)00326-7/fulltext

12:45 - Low Birth Weight as an Early-Life Risk Factor for Adult Stroke Among Men. https://www.jpeds.com/article/S0022-3476(21)00632-6/fulltext

19:25 - Bloodstream Infections in Preterm Neonates and Mortality-Associated Risk Factors. https://www.jpeds.com/article/S0022-3476(21)00561-8/fulltext

31:01 - In‐Hospital Respiratory Viral Infections for Patients with Established BPD in the SARS‐CoV‐2 Era. https://onlinelibrary.wiley.com/doi/10.1002/ppul.25714

39:07 - Neighborhood Disadvantage and Early Respiratory Outcomes in Very Preterm Infants with Bronchopulmonary Dysplasia. https://www.jpeds.com/article/S0022-3476(21)00643-0/fulltext

47:57 - Family history of asthma influences outpatient respiratory outcomes in children with BPD. https://onlinelibrary.wiley.com/doi/10.1002/ppul.25603

50:23 - End-of-Life Care Related Distress in the PICU and NICU: A Cross-Sectional Survey in a German Tertiary Center. https://www.frontiersin.org/articles/10.3389/fped.2021.709649/full

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#025 - Dr. Jimmy Turner - Burnout and moral injury in medicine Oct 10, 2021

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Dr. Jimmy Turner is a practicing anesthesiologist at Wake Forest. Dr. Turner hosts the physician philosopher podcast and blog where he take an uncurated and unapologetic look into physician life. He also cohosts the podcast Money meets medicine with Ryan Inman where they discuss finance topics that healthcare providers desperately need to know. He is also the author of the book The Physician Philosopher's Guide to Personal Finance. And finally, he is the founder of the alpha coaching experience which helps empower physicians who feel trapped in medicine and helps them practice medicine on their own terms.
https://thephysicianphilosopher.com
https://thephysicianphilosopher.com/podcasts/the-physician-philosopher/
https://thephysicianphilosopher.com/podcasts/money-meets-medicine/
https://coaching.thephysicianphilosopher.com/alpha-coaching-experience
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This podcast is proudly sponsored by Chiesi.

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#024 - Updates and Announcements (short) Oct 07, 2021

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#023 - Journal Club - End tidal vs TransCutaneous CO2, Sepsis in ELBW, Precedex vs morphine, burnout in pediatric fellows … and more! Oct 03, 2021

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03:20 - Use of Antenatal Corticosteroids at 22 Weeks of Gestation. https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2021/09/use-of-antenatal-corticosteroids-at-22-weeks-of-gestation

09:40 - Parent Preferences for Transparency of Their Child’s Hospitalization Costs. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2784398

19:55 - Monitoring of carbon dioxide in ventilated neonates: a prospective observational study. https://fn.bmj.com/content/early/2021/08/02/archdischild-2021-322138

31:00 - Medication Use in the Neonatal Intensive Care Unit and Changes from 2010-2018. https://www.jpeds.com/article/S0022-3476(21)00860-X/fulltext

37:50 - Early-Onset Sepsis Among Very Preterm Infants. https://pediatrics.aappublications.org/content/148/4/e2021052456

46:15 - Dexmedetomidine versus intermittent morphine for sedation of neonates with encephalopathy undergoing therapeutic hypothermia. https://www.nature.com/articles/s41372-021-00998-8

53:40 - Survival prediction modelling in extreme prematurity: are days important? https://www.nature.com/articles/s41372-021-01208-1

58:50 - Association of time of first corticosteroid treatment with bronchopulmonary dysplasia in preterm infants. https://onlinelibrary.wiley.com/doi/10.1002/ppul.25610

62:30 - Burnout and Perceptions of Stigma and Help-Seeking Behavior Among Pediatric Fellows. https://pediatrics.aappublications.org/content/148/4/e2021050393

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#022 - Dr. Minesh Khashu - NEC research, Fathers in the NICU and the future of neonatology Sep 26, 2021

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Pr Minesh Khashu is a clinical leader reimagining healthcare with a focus on systemic wide transformation, continuous quality improvement and family centered care. Prof Khashu has held multiple hospital, regional and national leadership roles in neonatal and perinatal care. Professor Minesh Khashu is a neonatologist at University Hospitals Dorset. He is the founder of the special interest group NEC (SIGNEC; signec.org). He also works actively on advocating for fathers' involvement in the NICU, and to that end, collaborated on the development of the neonatal DadPad app.
https://signec.org
https://thedadpad.co.uk/neonatal/
Check out his NEC paper on the use of bowel US: https://pubmed.ncbi.nlm.nih.gov/32398270/
You can get in touch with Dr. Khashu via:
Twitter - @mkrettiwt
Email - mineshkhashu@gmail.com
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