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    Business

    The Full Ratchet (TFR): Venture Capital and Startup Investing Demystified

    The podcast dedicated to demystifying Venture Capital. Nick Moran and Nate Pierotti interview VC’s & Startup Founders and on how they build great technology startups.

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    Copyright: © 2022

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    Latest Episodes:
    495. From CTO to $500M AUM: Entry Point Discipline, Why People Matter at Every Stage, and the AI-Driven Future of Banking (Victor Orlovski) Nov 03, 2025
    Show notes

    Victor Orlovski of R136 Ventures joins Nick to discuss From CTO to $500M AUM: Entry Point Discipline, Why People Matter at Every Stage, and the AI-Driven Future of Banking. In this episode we cover:

    • Exit Strategies and Market Challenges
    • Risks and Opportunities in Late-Stage Investments
    • Banking and FinTech Challenges
    • Future of Financial Markets and AI in Banking
    • Impact of AI on Financial Institutions
    • Role of Founders in the AI Era

    Guest Links:

    • Victor's LinkedIn
    • Victor's X
    • R136's LinkedIn
    • R136's Website

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 437. Why Founders Must Hold Their Ground, Why Investors Must Break Their Rules, and How Both Survive the Chaos (Binatti, Schroepfer, Ruscio) Oct 30, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Daniela Binatti of Pismo
    • Mike Schroepfer of Gigascale Capital
    • Joseph Ruscio of Heavybit

    We asked guests for the most important piece of advice that they'd share with folks early in their venture career.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 436. Visionary Founders, From Steve Jobs to Brian Armstrong, and the Leaders Blending Life Sciences and Technology (Schuler, Saxena, Bussgang) Oct 27, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Barry Schuler of DFJ Growth Ventures
    • Shashank Saxena of Sierra Ventures
    • Jeff Bussgang of Flybridge Capital

    We asked guests to discuss the most visionary founder that they've worked with and what makes them so special.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 435. Why Complacency Kills Momentum, The Cost of Over-Diligence, and Accepting the Limits of Control (Walsh, Wang, Hudson) Oct 23, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Shamin Walsh of BAM Ventures
    • Casber Wang of Sapphire Ventures
    • Charles Hudson of Precursor Ventures

    We asked guests to tell the most important lesson they've learned in their career.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    494. The Techstars Refresh, Why Bigger Isn't Better, Investing in the Seed-Strapping Era, and Why Quantum May Dwarf Every Tech Shift (David Cohen) Oct 20, 2025
    Show notes

    David Cohen of Techstars joins Nick to discuss The Techstars Refresh, Why Bigger Isn't Better, Investing in the Seed-Strapping Era, and Why Quantum May Dwarf Every Tech Shift. In this episode we cover:

    • Refocusing TechStars
    • Programs and Deal Structure
    • Selection Process and Follow-On Investments
    • Successful Programs and Founder Network
    • Geographic Distribution and AI-First Companies
    • Seed Strapping and Capital Efficiency
    • Vertical Networks and Emerging Technologies
    • Future of Venture and Trends

    Guest Links:

    • David's LinkedIn
    • David's X
    • Techstars' LinkedIn
    • Techstars' Website

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 434. How LPs Judge Performance, Managing Founder Conflict, and The Blind Spots Investors Must Confront (Schuler, Niehenke, Agarwal) Oct 16, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Barry Schuler of DFJ Growth Ventures
    • Alexander Niehenke of Scale Venture Partners
    • Medha Agarwal of Defy

    We asked guests to share the best question they've ever been asked by an allocator.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 433. The Art of Sensing Greatness, From Analytical to Intuitive Investing, and the Case for Industry Outsiders (Hsieh, Hilaly, Maples) Oct 13, 2025
    Show notes

    n this special segment of The Full Ratchet, the following Investors are featured:

    • Vince Hsieh of Cypress Growth Capital
    • Aaref Hilaly of Bain Capital Ventures
    • Mike Maples of Floodgate

    We asked guests to describe the biggest change to their investment philosophy over the course of their career

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 432. The Pain of Passing: Missed Bets on Uber, DoorDash, and Great Founders Who Proved Them Wrong (Shapiro, York, Dash) Oct 09, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Craig Shapiro of Collaborative Fund
    • Kyle York of York IE
    • Somesh Dash of IVP

    Each investor highlights a situation where they decided not to invest, why they passed, and how it played out.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    493. From Data Science to Drug Design: How AI Shifts Discovery, Target Validation, and Portfolio Construction (Jim Tananbaum) Oct 06, 2025
    Show notes

    Jim Tananbaum of Foresite Capital joins Nick to discuss From Data Science to Drug Design: How AI Shifts Discovery, Target Validation, and Portfolio Construction. In this episode we cover:

    • Data Science and Investment Approach
    • Investment Practices and Market Conditions
    • China's Role in Biotech and Regulatory Considerations
    • Impact of AI on Biotech and Healthcare
    • Healthcare Adoption of AI and Preventive Measures
    • Payers and Insurance Companies' Role
    • Lessons from Successful Investments
    • Generating Liquidity in a Sluggish Market
    • Future of GLP-1 Agonists

    Guest Links:

    • Jim's LinkedIn
    • Jim's X
    • Foresite's LinkedIn
    • Foresite's Website

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


    Investor Stories 431. Level Heads Build Enduring Companies, The Power of Persistence, and Why Conviction is Everything (Saxena, Delk, Rizik) Oct 02, 2025
    Show notes

    On this special segment of The Full Ratchet, the following Investors are featured:

    • Shashank Saxena of Sierra Ventures
    • Ryan Delk of Primer
    • Chris Rizik of Renaissance Venture Capital

    We asked guests for the most important piece of advice that they'd share with folks early in their venture career.

    The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area.

    We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.

    Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.


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