Solving the Puzzle with Dr. Datis Kharrazian - TopPodcast.com

View Top 200 Chart

Back to Rankings Page

Solving the Puzzle with Dr. Datis Kharrazian — Health & Fitness
Solving the Puzzle with Dr. Datis Kharrazian

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian’s experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases.

Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases.

His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life.

Hashimoto’s: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto’s hypothyroidism. This course has the most complete and current information for managing Hashimoto’s available.

You can find more information at drknews.com.

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Copyright: © Datis Kharrazian

Latest Episodes:

Episode 57: Dr. Joseph Pizzorno’s Insights on Functional Medicine and Environmental Health Oct 28, 2025

Show notes

In this episode, Dr. Kharrazian is joined by renowned physician Dr. Joseph Pizzorno, a pioneering voice in environmental medicine and toxicology. Together, they dive into the hidden world of environmental toxins—discussing the staggering number of chemicals we're exposed to every day, why testing for toxins can be more complex than most realize, and which common exposures may be silently sabotaging our health.

Dr. Pizzorno reveals the challenges in accurately measuring toxic load, the wide differences in our bodies’ abilities to detoxify, and why focusing on exposure and biological damage is often more useful than hunting for specific chemicals in the blood or urine. You'll learn about practical strategies for identifying and reducing toxin exposure, the synergistic effects of multiple chemicals, and simple steps you can take to support your body’s natural defenses.

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Assessing Exposure and Detox Challenges

03:37 "Assessing Synergistic Environmental Toxins"

07:09 "Toxic Load vs. Disease Correlation"

11:24 Tea Habits and Water Concentration

16:24 Chemical Impact on Neurological Health

17:48 Persistent Human-Made Molecules

23:20 Bisphenols Lowering Children's IQ

26:18 Chemical Food Sources & Glyphosate Exposure

28:26 Cerrillini's Impact on Glyphosate Regulation

32:50 "Assessing Kidney Toxicity via EGFR"

36:44 "Enhancing Body Detoxification"

37:42 "Detox Strategy: Sweat and Monitor"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 56: Labs To Monitor In Patients With Hemochromatosis Oct 10, 2025

Show notes

In today’s episode, Dr. Christy Sutton breaks down the crucial markers to monitor for iron overload, from classic liver enzymes and iron panels to the often-overlooked cardiovascular and autoimmune risk factors that can clue you into complications before they become serious. You’ll learn about ancillary labs to watch for side effects in the liver, kidneys, brain, hormones, cardiovascular system, and more. Dr. Sutton unpacks the practical nuances of interpreting test results, why “mildly elevated” liver enzymes should never be dismissed, and how overlapping factors like copper, magnesium, and vitamin deficiencies can shape both diagnosis and management.

Join Dr. Christy Sutton's 6-hour Kharrazian Institute Master Class on Iron Overload & Undiagnosed Anemias and learn the protocols 90% of practitioners miss.

Enroll: pages.kharrazianinstitute.com/sutton-anemia

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Hemochromatosis Patient Lab Monitoring

04:45 Glutathione Testing and Liver Health

06:35 Type 1 Diabetes and Celiac Link

12:24 Hemochromatosis and Cardiovascular Risk

16:29 Copper and Ceruloplasmin Testing Insights

19:49 Copper, Iron, Zinc: Balancing Act

24:09 "Solving The Puzzle" Podcast Promo

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 55: Navigating Anemia Oct 06, 2025

Show notes

Anemia affects millions but is often misunderstood or oversimplified. Anemia isn’t just about having low iron. It means you don’t have enough healthy red blood cells or hemoglobin to get vital oxygen to your tissues, organs, and brain.

Host Chrissy Sutton breaks down the many different forms of anemia, from iron-deficiency to anemia of inflammation, and even discusses why you can actually have too much iron and still be anemic.

We’ll explore how to spot anemia not just with lab work, but by recognizing physical signs like paleness, fatigue, brittle nails, and even changes in your tongue and the whites of your eyes. Dr. Sutton highlights why anemia is more than just feeling tired—it’s tied to everything from exercise intolerance and heart palpitations to developmental delays in children and increased risk for disorders like ADHD.

This episode also unpacks the confusing overlap between high ferritin from inflammation versus hemochromatosis, goes in-depth on the impact of pregnancy and menstruation on iron levels, and shares actionable tips for both clinicians and patients.

To learn more, enroll in the Master Class “Iron Overload and Undiagnosed Anemias” at https://pages.kharrazianinstitute.com/sutton-anemia

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Anemia and Heart Strain Connection

10:13 Low Iron Risks in Pregnancy

11:40 Early Pregnancy Iron Supplementation

18:14 Acid Reducers Impact Iron Levels

26:50 Pregnancy: Nutrient Absorption Challenges

31:43 "Decoding Iron Deficiency Causes"

34:08 Iron Deficiency Anemia Symptoms

40:51 Vitamin A Deficiency Risk Factors

47:24 "Copper's Role in Iron Regulation"

53:34 Diagnosing Hemolytic Anemia

54:26 Managing Aplastic Anemia Basics

01:01:52 Lead Cabinet Toxicity Solved

01:06:09 Ferritin Management Without Blood Removal

01:11:14 Digestive Challenges of Low Stomach Acid

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 54: Understanding Dyslexia and Childhood Processing Disorders Sep 28, 2025

Show notes

In this episode, Dr. Kharrazian dives into childhood developmental disorders, with a special focus on dyslexia and processing challenges. Learn why children struggle with reading, writing, or social interaction and how sensory and motor coordination issues are linked to brain development.

The conversation breaks down the different types of developmental disorders, from learning and sensory processing to motor skills, psychological health, and communication abilities. Dr. Kharrazian will clarify what dyslexia really is and explore its genetic roots, signs, symptoms, and why early diagnosis is critical.

You’ll also hear insights on sensory processing disorders, motor tics, behavioral challenges, and how functional medicine can support children—and adults—facing these challenges by optimizing brain health and development.

To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Identifying Learning Disorder Pathways

05:15 Dyslexia Awareness and Diagnosis Progress

15:37 "Dyslexia-Induced Cognitive Fatigue"

19:40 Early Dyslexia Impact on Children

25:35 Dyslexia: Genetics and Coping Strategies

30:01 Dyslexia Screening: Nine Yes Indicators

33:17 Supporting Dyslexia: Diagnosis and Brain Health

37:23 Factors Impacting Brain Development

46:34 Neurorehab: Develop Weak Brain Areas

48:17 Sensory and Motor Disorders in Autism

54:02 Frontostriatal Pathway and Tics

01:00:47 "Understanding PANDAS/PANS in Children"

01:08:19 Comprehensive Child Development Disorder Checklist

01:09:25 "Pediatric Functional Medicine Overview"

01:14:30 Functional Medicine & Nutrition Education

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 53: Functional Medicine Approaches to Childhood Neurodevelopmental Disorders Sep 16, 2025

Show notes

In this episode, Dr. Kharrazian dives into the rising rates and complexities of childhood developmental disorders, such as autism, ADHD, dyslexia, and sensory processing issues, and discusses why so many parents and even healthcare professionals feel overwhelmed or unsupported when it comes to helping these children thrive.

Whether you’re a healthcare practitioner, parent, or someone interested in the foundations of healthy brain development, this conversation will give you an understanding of childhood developmental challenges and actionable tools to make a difference.

To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Muscle Mass Essential for Longevity"

03:05 Sarcopenia Significantly Increases Mortality Risk

08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise

10:56 Gut-Muscle Axis: Impact on Fitness

13:09 Gut-Muscle Connection: Sarcopenia Insights

17:33 Muscle Metabolism and Protein Sufficiency

20:02 Protein Intake Crucial for Muscle Maintenance

25:30 Muscle Issues: Causes and Solutions

27:26 Creatine: Muscle Boost and Benefits

32:19 Accelerated Muscle Aging Process

35:52 Improving Muscle Metabolism with Autophagy

38:58 Statins Linked to Muscle Dysfunction

40:00 Statin Impact on Muscle Health

43:08 Trigger Points and Myofascial Pain

48:17 Myofascial Syndromes and Muscle Dysfunction

52:52 Functional Medicine Training and Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 52: The Impact of Bone and Joint Health on Chronic Illness Recovery Sep 08, 2025

Show notes

In this episode, Dr. Datis Kharrazian explains what happens to our muscles as we age and why maintaining muscle mass is crucial for mobility, bone density, cognition, metabolic and immune health, and recovery from chronic illness. You’ll hear actionable insights about sarcopenia (age-related muscle loss), the muscle-gut connection, the power of myokines, and how hormones, nutrition, and strategic exercise can make a life-or-death difference.

You’ll hear evidence-based guidance on protein intake, key nutrients, common causes of dysfunctional muscle metabolism, and how to identify and address issues like statin-induced myopathy and abnormal muscle tone.

To dive deeper, enroll in the Kharrazian Institute’s Degenerative Joint, Muscle, and Bone Conditions Course.

Sign up here: https://pages.kharrazianinstitute.com/ki-bone-joint

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Muscle Mass Essential for Longevity"

03:05 Sarcopenia Significantly Increases Mortality Risk

08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise

10:56 Gut-Muscle Axis: Impact on Fitness

13:09 Gut-Muscle Connection: Sarcopenia Insights

17:33 Muscle Metabolism and Protein Sufficiency

20:02 Protein Intake Crucial for Muscle Maintenance

25:30 Muscle Issues: Causes and Solutions

27:26 Creatine: Muscle Boost and Benefits

32:19 Accelerated Muscle Aging Process

35:52 Improving Muscle Metabolism with Autophagy

38:58 Statins Linked to Muscle Dysfunction

40:00 Statin Impact on Muscle Health

43:08 Trigger Points and Myofascial Pain

48:17 Myofascial Syndromes and Muscle Dysfunction

52:52 Functional Medicine Training and Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 51: How Bone, Joint, and Muscle Health Influences Chronic Disease Recovery Aug 26, 2025

Show notes

In this episode, you’ll learn how movement directly influences your metabolism, immune system, brain function, and even the diversity of your gut microbiome. Dr. Kharrazian explains the critical role of messenger proteins released during physical activity, why maintaining muscle mass and bone density is key to longevity, and how inflammation can undermine your body’s ability to recover.

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Introduction to the Podcast

00:30 How Physical Movement Impacts Health

01:54 Bone Volume, Osteopenia, and Health Consequences

02:56 Toxic Chemicals, Bone Loss, and Aging

03:50 Muscle Mass, Sarcopenia, and Mortality

04:38 Movement, Depression, and Brain Chemistry

05:15 Movement, Myokines, and Immune Function

05:59 Microbiome Diversity, Gut Health, and Inactivity

06:32 Overtraining Syndrome and its Red Flags

07:11 Exercise, Mitochondrial Health, and Chronic Disease

07:49 Movement & Brain Health: Repair, Mood, and Cognitive Disorders

08:25 Sedentary Lifestyle in Children & Sarcopenia Risks

09:45 Medical Management of Osteoporosis and Arthritis

10:55 Inflammation, Muscular and Skeletal Degeneration

12:16 Body Fat, Skinny Fat, and Inflammation

12:46 Insulin Surges and Systemic Inflammation

13:31 Microbiome, Leaky Gut, and Chronic Inflammatory Disease

16:04 Food, Environmental Toxins, and Inflammation

18:09 Protein Intake and Recovery from Chronic Disease

19:12 Sleep, Sleep Apnea, and Bone Health

19:57 Regenerative Medicine Therapies

21:34 Conclusion and Podcast Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 50: The Role of Relationships and Support in Managing Autoimmunity May 06, 2025

Show notes

In this episode, we dive into the environmental and lifestyle factors that impact autoimmunity. From evaluating case reviews to understanding the significance of relationships, stress, and sleep, we explore how these elements shape autoimmune diseases. Discover how proper lifestyle medicine is crucial, and why it’s more than just about supplements. Learn about sleep disorders, chemical exposures, and the role of circadian rhythms in modulating the immune system. For more details, visit drknews.com.

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/

00:00 Patient Screening and Case Review Process

07:55 Sleep's Impact on Immune Function

11:27 Rheumatoid Arthritis: Sleep's Vital Role

16:15 Stress, Autoimmunity, and IL-17 Dynamics

22:13 Exercise & Autoimmunity: Personalized Approach

26:57 Chemical Bio-Transformation: Can vs. Can't

31:17 Chemical Sensitivity and Immune Response

37:45 BPA Study on Autoimmunity Impact

44:16 "Identifying Active Heavy Metal Exposure"

50:48 Chemical & Immune Tolerance Issues

54:42 Avoiding Challenge Tests: Prioritize Immune Reactivity

01:01:47 Optimizing Liver Detox and Nutrition

01:06:54 Glutathione Protocol for Heavy Metals

01:11:03 Glutathione Inhalation for Lung Health

01:14:38 Dr. Kharrazian Podcast Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 49: Navigating Parasitic Infections Feb 10, 2025

Show notes

In this episode of "Solving the Puzzle with Dr. Datis Kharrazian," we dive into the intricate world of gastrointestinal health, focusing specifically on the common pathogen Helicobacter pylori (H. pylori) and various parasites affecting the human body. Dr. Kharrazian as explores the pathophysiological mechanisms of these infections, their clinical presentations, and the potential systemic health issues they can trigger, including autoimmune diseases, cardiovascular risks, and gastrointestinal disturbances.

Learn more at drknews.com

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/

00:00 H. Pylori Pathogenesis Explained

05:45 H. Pylori: Symptoms and Risks

11:58 H. Pylori's Broad Health Impact

19:24 Urea Breath Test for H. Pylori

25:40 Digestive Health Supplement Strategies

32:05 Malaria Symptoms and Transmission Overview

36:49 Dormant Malaria Parasite Reactivation

39:24 Asymptomatic Malaria: Hidden Transmission Risk

46:07 Parasite Transmission Via Poor Hygiene

51:12 Deworming Benefits for HIV Patients

57:24 Mixed Results in Autoimmune Disease Treatment

01:04:05 "Chronic Infections and Immune Function"

01:06:46 Sleep's Role in Immunity

01:14:47 Bile Acids: Key Immune Regulators

01:21:25 Mucosal Immunity and Microbiome Health

01:22:37 Factors Affecting Microbiome Diversity

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Episode 48: Neurological Health and Interventions with Randy Vawdry, NP-C Feb 07, 2025

Show notes

In today's episode, Dr. Kharrazian interviews Randy Vawdry, NP-C, a respected nurse practitioner who has carved a niche in the realm of functional medicine. With a background ranging from nursing home care to urgent care, Randy brings a wealth of practical experience to our discussion about neurological health and treatment. We dive into his innovative approaches to neurological health, exploring how metabolic health, hormone optimization, and understanding traumatic brain injuries can revolutionize patient care. Randy shares invaluable insights from his clinical practice and educational endeavors, shedding light on how practitioners can master the complexities of brain health to improve outcomes for themselves, their patients, and even their loved ones.

SIGN UP HERE: http://pages.kharrazianinstitute.com/vawdrey-neurological-disorders

Learn more at kharrazianinstitute.com

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/

00:00 Master Class with Expert Clinician

04:26 Optimizing Neurological Health Priorities

06:35 Value of Mastering Functional Medicine

10:16 Prioritize Brain Health for Practitioners

13:18 Simplifying Complex Concepts

17:40 Lifestyle Medicine and Hormone Optimization

20:41 Rethinking Functional Medicine Approach

24:35 Functional Medicine's Inexperience Problem

28:33 "Symptoms Are the Disease"

29:17 Lifestyle Choices and Alzheimer's Prevention

33:59 "Promoting Continuous Glucose Monitoring"

37:19 Master Class on Neurological Care

39:27 Podcast Disclaimer and Dr. Kharrazian's Disclosures

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Related Podcasts