Science Changing Life

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Episode 18 - Biodiversity beyond the horizon: Scripps Research Magazine Feb 18, 2020

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Research discoveries brought to life! In today’s segment, we explore Scripps Research’s Natural Products Discovery Center, a historic natural collection that may hold the key to thousands of future therapies. This article is taken from the Fall 2019 edition of our Scripps Research Magazine. Show notes: Digital version of our Fall 2019 magazine: https://issuu.com/endeavor-scripps-research/docs/magazine_fall2019_pageflipper?embed_cta=read_more&embed_context=embed&embed_domain=www.scripps.edu Subscribe to receive the Scripps Research magazine: https://signup.e2ma.net/signup/1879047/1890109/ The Scientist: Scripps Research acquires Pfizer’s massive microbial library https://www.the-scientist.com/news-opinion/scripps-acquires-pfizers-massive-microbial-library-66923 West Palm Beach News: Local organization works to create new medicine https://www.wpbf.com/article/local-organization-works-to-create-new-medicine-scripps-research-jupiter/30813823 The Shen Lab: https://www.scripps.edu/shen/

Episode 17 - Time is ticking against Lyme: Scripps Research Magazine Jan 13, 2020

Show notes

Research discoveries brought to life! In today’s short story, we find out how medicines designed for our pets are now being repurposed by our scientists to provide a lasting, protective vaccine against Lyme disease. This article is taken from the Fall 2019 edition of our Scripps Research Magazine. Show notes: Digital version of the Scripps Research Fall 2019 magazine: https://www.scripps.edu/news-and-events/connect-with-us/magazine-current-issue/index.html Subscribe to receive the Scripps Research magazine: https://signup.e2ma.net/signup/1879047/1890109/ US News & World Report: The growth and reach of Lyme disease: https://www.usnews.com/news/healthiest-communities/articles/2019-12-10/lyme-disease-diagnoses-grow-in-private-insurance-claims

Episode 16 – David Biello: What Makes a Great Science TED Talk Nov 27, 2019

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David Biello is an award-winning journalist and the scientific curator for TED. Listen as we talk about his favorite areas of science, how to craft a compelling narrative and being obsessed with blind cavefish. Show notes: David’s profile at TED (and book link) https://www.ted.com/speakers/david_biello David’s work at Scientific American https://www.scientificamerican.com/author/david-biello/ TED talk – ‘Clues to prehistoric times, found in blind cavefish’ https://www.ted.com/talks/prosanta_chakrabarty_clues_to_prehistoric_times_found_in_blind_cavefish TED talk – ‘What happens in your brain when you taste food’ https://www.ted.com/talks/camilla_arndal_andersen_what_happens_in_your_brain_when_you_taste_food Social media: Twitter: @dbiello Remember to follow @ScrippsResearch on Twitter, Instagram, Facebook and LinkedIn

Episode 15 – Kristen Johnson & Maria Millan: Regenerative Medicine for Osteoarthritis Jul 21, 2019

Show notes

Dr. Kristen Johnson is a lead investigator at Calibr, the drug discovery division of Scripps Research. Dr. Maria Millan is the President and CEO of the California Institute for Regenerative Medicine (CIRM). Listen as we talk about the world’s largest stem cell bank, restoring healthy cartilage to patients, and the advantages of non-profit research. Show notes: Kristen’s talk in the Scripps Research Front Row Lecture Series https://www.youtube.com/watch?v=WRzQniqUlHo&t=1941s Coverage of KA34 in the San Diego Union Tribune https://www.sandiegouniontribune.com/business/biotech/sd-me-scripps-cartilage-drug-arthritis-20180624-story.html Maria’s profile at CIRM https://www.cirm.ca.gov/about-cirm/cirm-leadership Social Media: Follow @ScrippsResearch on Twitter, Instagram, Facebook and LinkedIn Follow CIRM on Twitter:@CIRMnews ; Instagram:@cirm_stemcells ; Facebook: @California InstituteForRegenerativeMedicine

Ep. 14–Brian Fiske & Jeff Kelly: Accelerating Discoveries to Treat Neurodegenerative Disease May 28, 2019

Show notes

Dr. Brian Fiske is the Senior Vice President for Research Programs at the Michael J. Fox Foundation for Parkinson’s Disease. Professor Jeff Kelly is in the Department of Chemistry at Scripps Research. Listen as we talk about biomarkers for early disease detection, the importance of long-term human trials, and how Parkinson’s disease could originate in the gut. Show notes: Dr. Fiske’s bio at MJFF https://www.michaeljfox.org/foundation/leaders.html?subcatid=381 Prof. Kelly’s bio at Scripps Research https://www.scripps.edu/faculty/kelly/ Coverage of FDA approval of Tafamidis https://www.scripps.edu/news-and-events/press-room/2019/20190506-fda-approved-tafamidis.html https://www.fda.gov/news-events/press-announcements/fda-approves-new-treatments-heart-disease-caused-serious-rare-disease-transthyretin-mediated Social Media: Twitter/Instagram: @MichaelJFoxOrg Remember to follow @ScrippsResearch on Twitter, Instagram, Facebook and LinkedIn

Episode 13 – Eric Topol: High Performance Medicine – How Technology Can Bring Back Humanity Mar 12, 2019

Show notes

Dr. Eric Topol is the Founder and Director of The Translational Institute at Scripps Research. Listen as we talk about bringing back empathy in medicine, smartphone ultrasounds and the best media for absorbing scientific information. Show notes: Translational Institute at Scripps Research https://www.scripps.edu/science-and-medicine/translational-institute/ Eric’s new book: Deep Medicine https://www.amazon.com/Deep-Medicine-Artificial-Intelligence-Healthcare/dp/1541644638 Current and future applications of technology in healthcare https://www.nature.com/articles/s41591-018-0300-7.pdf The Topol Review on the future of the NHS https://topol.hee.nhs.uk/ Eric’s 2016 Tedx Talk https://www.youtube.com/watch?v=y9nS1b7ifSE Twitter: @EricTopol Facebook: @ScrippsRTI Instagram: @erictopol1

Episode 12 – Arnab Chatterjee: Teaching Old Drugs New Tricks Jan 27, 2019

Show notes

Dr. Chatterjee is the Vice President of Medicinal Chemistry at Calibr, the biotechnology division of Scripps Research. Listen as we talk about re-purposing existing compounds for new diseases, the future of robotics in drug discovery and our favorite Superheroes. Show notes: About Calibr https://www.scripps.edu/science-and-medicine/calibr/about/index.html ReFRAME Initiative https://www.scripps.edu/news-and-events/press-room/2018/20181003-reframe-calibr.html Footage of Calibr’s robots in action https://www.statnews.com/2018/12/10/calibr-drug-compounds-mined-new-treatments/ Use of the ReFRAME library to treat Cryptosporidium infection https://www.pnas.org/content/115/42/10750

Episode 11 – Matthias Pauthner: Novel Approaches to Combat Infectious Disease Dec 10, 2018

Show notes

Matthias is based in the Department of Immunology and Microbiology at Scripps Research, working in Prof. Kristian Andersen’s Lab. Listen as we talk about wearable devices to monitor disease progression, research field-trips to West Africa and fancy nights at the symphony. **p.s. if you enjoyed the Christmas jingle, Matthias and I are currently working on an album** Show notes: Andersen Laboratory https://andersen-lab.com/ CViSB Consortium https://cvisb.org/ Burton Laboratory https://www.scripps.edu/burton/ @mpauthner on twitter @cvisb on twitter @mattmirabilis on Instagram

Episode 10 – Alyssa Shepard: Harnessing Social Media in Science Nov 16, 2018

Show notes

Alyssa is based in the Department of Molecular Medicine at Scripps Research, under the supervision of Prof. Joseph Kissil. Listen as we talk about cancer biology, naked mole-rats and practical tips for improving science communication. Show notes: Kissil Laboratory https://www.scripps.edu/kissil/ Alyssa’s blog https://thecurioussheep.net/blog/ @the_curioussheep on Instagram @_curioussheep on twitter

Episode 9 - Courtney Miller: How To Forget Addictions Oct 18, 2018

Show notes

Prof. Miller is based in the Department of Molecular Medicine at Scripps Research. Listen as we talk about methamphetamine-use disorder, short- and long-term memory formation, and Breaking Bad. Show notes: Prof. Miller’s Scripps Research bio https://www.scripps.edu/faculty/miller/ Pearson Center for Alcoholism and Addiction http://www.pearsoncenter.org/laboratories-pearson-center/ News coverage of recent work https://eurekalert.org/pub_releases/2018-09/sri-ouc091418.php @millerlab3 on twitter

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