Science Changing Life

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Episode 28 – Personalized genetic testing: Scripps Research Magazine Aug 16, 2021

Show notes

We roll on with part 3 of our healthy aging series. We examine the role of our DNA blueprint in the risk of cardiovascular disease, as well as how understanding our personal genetic risk scores could help us avoid that deadly heart attack. This article is taken from the Summer 2021 of our award-winning Scripps Research Magazine. Show notes: Explore the Scripps Research Magazine https://magazine.scripps.edu/

Episode 27 – Overcoming arthritis: Scripps Research Magazine Aug 09, 2021

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In the second of this series on healthy aging, we reveal how Scripps Research scientists are developing interventions to remove stiff, achy joints from the aging equation. This article is taken from the Summer 2021 of our award-winning Scripps Research Magazine. Show notes: Explore the Scripps Research Magazine https://magazine.scripps.edu/

Episode 26 – Cellular secrets to a longer life: Scripps Research Magazine Aug 02, 2021

Show notes

Peer into the future of healthy aging. In this episode (the first of a 5-part series), we shed new light on how our cells and organs work together to influence longevity, and how newly discovered molecules may be able to block biological degeneration. This article is taken from the Summer 2021 of our award-winning Scripps Research Magazine. Show notes: Explore the Scripps Research Magazine https://magazine.scripps.edu/

Episode 25 - Ed Ramos: Reversing diabetes with personalized nutrition May 10, 2021

Show notes

Dr. Ed Ramos is director of Digital Clinical Trials for the Scripps Research Digital Trials Center. Listen as we talk about empowering the individual with wearable health devices, the worst foods for spiking our blood sugar and the importance of lifelong flexibility. Show notes: PROGRESS study enrollment https://progress.scripps.edu/ PROGRESS study explainer video https://www.youtube.com/watch?v=UUdaMojHLuk&t=74s Ed’s bio https://www.scripps.edu/science-and-medicine/translational-institute/about/people/ed-ramos/ Scripps Research Digital Trials Center https://digitaltrials.scripps.edu/

Episode 24- Eric Topol & Andrew Ward: How Spike Protein Discoveries Drove Coronavirus Vaccine Design Dec 23, 2020

Show notes

Another special edition featuring an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Andrew Ward in the Department of Integrative Structural and Computational Biology at Scripps Research. Listen as they talk about structural biology as a gamechanger in coronavirus research, what makes the SARS-CoV-2 spike protein crucial for vaccine design, and what the latest coronavirus mutations mean for the pandemic. Show notes: The Ward Lab: https://ward.scripps.edu/ Dr. Eric Topol’s bio: www.scripps.edu/faculty/topol/ Inside the Lab That Invented the COVID-19 Vaccine: https://www.youtube.com/watch?v=-92HQA0GcI8&amp%3Bfeature=youtu.be Solving the spike protein’s 3D structure: https://www.scripps.edu/newsandviews/e_20160307/ward.html Science, Simplified: How vaccines work against COVID-19 https://youtu.be/uWGTciX795o Scripps Research on social media: Twitter, Instagram: @scrippsresearch Facebook: @ScrippsResearchInstitute LinkedIn: the-scripps-research-institute

Episode 23 – Daphne Lurie: Taking Care of your Mental Health Dec 03, 2020

Show notes

Dr. Daphne Lurie is a California-licensed clinical psychologist and Director of the Counseling and Psychological Services (CAPS) on the Scripps Research La Jolla campus. Listen as we talk about the impact of the COVID-19 pandemic on mental health trends, using mindfulness to become more efficient and ziplining in Costa Rica. Show notes: Daphne’s Scripps Research profile: https://www.scripps.edu/about/campus-resources/counseling-and-psychological-services/about-us/ Counseling and Psychological Services (CAPS) at Scripps Research: https://www.scripps.edu/about/campus-resources/counseling-and-psychological-services/ Other mindfulness resources discussed: A Mindfulness-Based Stress Reduction Workbook - Bob Stahl, Elisha Goldstein The Mindful Self-Compassion Workbook - Kristin Neff, Christopher Germer

Episode 22 – Discovery in an Era of Social Distancing: Scripps Research Magazine Nov 16, 2020

Show notes

Stories brought to life! Today’s audio adventure comes from the Fall 2020 edition of our Scripps Research Magazine. We dive into the adaptations made by institute researchers during the COVID-19 pandemic to ensure both safety and continued scientific discovery. Show notes: Explore our Scripps Research Magazine and subscribe https://www.scripps.edu/news-and-events/connect-with-us/

Episode 21 - Kara Marshall: The Science of Bladder Control Oct 14, 2020

Show notes

Dr. Kara Marshall is based in the Department of Neuroscience at Scripps Research, working as a postdoctoral researcher in Professsor Ardem Patapoutian’s lab. Listen as we talk about the circuitry involved in urination, burst bladders and improv comedy. Show notes: The Patapoutian Lab https://patapoutianlab.org/ Kara’s recent discovery on bladder function https://www.nature.com/articles/s41586-020-2830-7 Deciphering how the body’s cells sense touch https://www.nature.com/articles/d41586-019-03955-w Proprioception: the silent ‘sixth’ sense https://www.vox.com/the-highlight/2019/11/22/20920762/proprioception-sixth-sense

Episode 20 – Eric Topol & Dennis Burton: Antibodies, Vaccines and the Current State of COVID-19 Sep 01, 2020

Show notes

Today’s special edition features an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Dennis Burton, Chair of the Department of Immunology and Microbiology at Scripps Research. Listen as they talk about antibody cocktail treatments, the mystery of “longhaul” COVID-19 symptoms and how close we are to developing a coronavirus vaccine. Transcript of today's episode https://www.scripps.edu/covid-19/videos/topol-burton/index.html Dr. Eric Topol’s bio https://www.scripps.edu/faculty/topol/ Prof. Dennis Burton’s bio https://www.scripps.edu/faculty/burton/ Efficacy of convalescent plasma https://www.sandiegouniontribune.com/business/biotech/story/2020-08-30/hundreds-of-san-diegans-with-covid-19-have-already-been-treated-with-plasma-but-does-it-work “COVID longhaulers” https://www.theatlantic.com/health/archive/2020/08/long-haulers-covid-19-recognition-support-groups-symptoms/615382/ Coronavirus vaccine Q&A with Prof. Dennis Burton https://www.sandiegouniontribune.com/business/biotech/story/2020-07-26/q-a-an-update-on-the-race-for-a-covid-19-vaccine-scripps-research-immunologist-dennis-burton Dr. Eric Topol on social media: Twitter: @EricTopol Instagram: @erictopol1 Scripps Research on social media: Twitter, Instagram: @scrippsresearch Facebook: @ScrippsResearchInstitute LinkedIn: the-scripps-research-institute

Episode 19 – Amanda Roberts: Mice in Outer Space Jul 09, 2020

Show notes

Dr. Amanda Roberts is the Senior Scientific Director of the Mouse Behavioral Core at Scripps Research. Listen as we talk about microgravity as a model of accelerated aging, NASA’s top-secret agents and what happens to slime in space. (Image Credit: Andrew Roberts) Show notes: Amanda’s research profile: https://vivo.scripps.edu/display/RobertsAmanda Replay of the NASA launch (action around ~11 minutes in): https://www.cnbc.com/2019/07/25/spacex-livestream-watch-the-company-launch-nasa-crs-18-on-a-falcon-9.html News coverage of the NASA mouse studies: https://www.nasa.gov/feature/ames/studying-behavior-in-space-shows-mice-adapt-to-microgravity https://qz.com/1597197/nasas-space-station-mice-loved-microgravity/

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