Research To Practice | Oncology Videos

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**Research To Practice | Oncology Videos**

Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

Latest Episodes:

Breast Cancer | Oncology Today with Dr Neil Love: HER2-Positive Metastatic Breast Cancer Jan 26, 2023

Show notes

Featuring an interview with Professor Giuseppe Curigliano, including the following topics:

Vision for treating and curing HER2-positive metastatic breast cancer (mBC) in the future (0:00)
Optimal treatment of HER2-positive mBC with brain metastases (7:42)
Screening for and management of T-DXd-related interstitial lung disease (17:32)
Gastric toxicities associated with the tucatinib/trastuzumab/capecitabine regimen and with T-DXd; differences in the toxicity profiles of these therapies between patients with HER2-positive and HER2-low breast cancer (23:50)
Approach to endocrine therapy for triple-positive disease; emerging data with the AKT inhibitor capivasertib (28:43)
Case: A woman in her mid 40s with a family history of breast cancer and upper limb soft tissue sarcoma who presents with a right breast lump and axillary adenopathy on self-examination (35:44)

CME information and select publications

Targeted Therapy in Non-Small Cell Lung Cancer | Gregory J Riely, MD, PhD Jan 24, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Targeted Therapy for Non-Small Cell Lung Cancer — Faculty Presentation 2: Therapeutic Approaches for Patients with Other Actionable Genomic Alterations — Dr Gregory Riely

CME information and select publications

Targeted Therapy in Non-Small Cell Lung Cancer | Zofia Piotrowska, MD, MHS Jan 24, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Targeted Therapy for Non-Small Cell Lung Cancer — Faculty Presentation 1: Management of Non-Small Cell Lung Cancer with an EGFR, ALK or ROS1 Abnormality — Dr Zofia Piotrowska

CME information and select publications

Targeted Therapy for Non-Small Cell Lung Cancer | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Targeted Therapy for Non-Small Cell Lung Cancer Jan 24, 2023

Show notes

Featuring perspectives from Drs Zofia Piotrowska and Gregory Riely, including the following topics:

Introduction: What Is Targeted Therapy? (0:00)
EGFR-Activating Mutations (12:23)
EGFR Exon 20 Insertion Mutations (27:54)
ALK and ROS1 Rearrangements (31:31)
HER2 Mutations (36:17)
NRG1 Fusions (45:39)
RET Fusions (49:07)
MET Exon 14 Mutations (53:10)
KRAS G12C Mutations (56:01)

CME information and select publications

Chronic Lymphocytic Leukemia | Deborah Stephens, DO Jan 20, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Chronic Lymphocytic Leukemia — Faculty Presentation 2: Treatment of Relapsed/Refractory CLL; Novel and Investigational Strategies — Dr Deborah Stephens

CME information and select publications

Chronic Lymphocytic Leukemia | Jennifer R Brown, MD, PhD Jan 20, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Chronic Lymphocytic Leukemia — Faculty Presentation 1: Optimizing the First-Line Management of Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) — Dr Jennifer Brown

CME information and select publications

Chronic Lymphocytic Leukemia | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Chronic Lymphocytic Leukemia Jan 20, 2023

Show notes

Featuring perspectives from Drs Jennifer Brown and Deborah Stephens, including the following topics:

Introduction: First-Line Treatment of Chronic Lymphocytic Leukemia (0:00)
Combining Bruton Tyrosine Kinase (BTK) Inhibitors with Venetoclax; Venetoclax Consolidation (36:57)
Noncovalent BTK Inhibitors; Pirtobrutinib (42:59)
CAR T-Cell Therapy; Lisocabtagene Maraleucel (51:26)
Richter's Transformation (56:31)

CME information and select publications

Multiple Myeloma | Meet The Professor: Optimizing the Management of Multiple Myeloma — Part 3 Jan 19, 2023

Show notes

Featuring perspectives from Dr Shaji Kumar, including the following topics:

Introduction (0:00)
Case: A woman in her early 70s with standard-risk newly diagnosed multiple myeloma (NDMM), "borderline transplant-eligible," receiving daratumumab-RVd, with transportation limitations and missed treatments — Neil Morganstein, MD (11:50)
Case: A woman in her early 50s with Stage III, high-risk NDMM (1q21+), multiple bone lesions and acute renal impairment after RVd and transplant, now on the DRAMMATIC trial — Vignesh Narayanan, MD (24:43)
Cases: A man in his early 60s with relapsed t(11;14) multiple myeloma (MM) and renal failure after RVd and ASCT, now on venetoclax/bortezomib/dexamethasone and a woman in her mid 50s with high-risk t(11;14) smoldering MM — Amany R Keruakous, MD, MS and Hans Lee, MD (32:59)
Case: A man in his late 70s with transplant-ineligible NDMM who received daratumumab with lenalidomide/dexamethasone but discontinued daratumumab because of a severe rash — Yanjun Ma, MD (41:32)
Case: A man in his mid 80s with a history of non-muscle-invasive bladder cancer, now with multiregimen-refractory MM and biochemical disease progression — Spencer Henick Bachow, MD (45:49)

CME information and select publications

Breast Cancer | Joyce O'Shaughnessy, MD Jan 17, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Breast Cancer — Faculty Presentation 2: Metastatic Breast Cancer — Dr Joyce O'Shaughnessy

CME information and select publications

Breast Cancer | Professor Peter Schmid, FRCP, MD, PhD Jan 17, 2023

Show notes

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Breast Cancer — Faculty Presentation 1: Localized Breast Cancer — Professor Peter Schmid

CME information and select publications