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    Science

    Research To Practice | Oncology Videos

    Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

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    Copyright: Copyright © 2023 Research To Practice. All Rights Reserved.

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    Latest Episodes:
    Non-Small Cell Lung Cancer | Oncology Today with Dr Neil Love: Management of HER2-Altered Non-Small Cell Lung Cancer Feb 21, 2023
    Show notes

    Featuring perspectives from Dr Bob Li, including the following topics:

    • Evolution of targeted therapy for HER2-altered non-small cell lung cancer (NSCLC) (0:00)

    • Incidence and management of HER2 amplifications and mutations in NSCLC (10:45)

    • Role of ErbB/HER protein family biology in lung cancer (19:03)

    • Current and emerging roles of antibody-drug conjugates in lung cancer (33:43)

    • Considerations for clinical trial participation and improving access to care for patients with cancer (55:08)

    • Management of trastuzumab deruxtecan-associated interstitial lung disease (1:03:18)

    • Future of HER2-targeted therapy in lung cancer and beyond (1:14:39)

    CME information and select publications


    Hodgkin and Non-Hodgkin Lymphomas | Laurie H Sehn, MD, MPH Feb 18, 2023
    Show notes

    Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Hodgkin and Non-Hodgkin Lymphomas — Faculty Presentation 2: Follicular Lymphoma and Mantle Cell Lymphoma — Dr Laurie Sehn

    CME information and select publications


    Hodgkin and Non-Hodgkin Lymphomas | Christopher R Flowers, MD, MS Feb 18, 2023
    Show notes

    Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Hodgkin and Non-Hodgkin Lymphomas — Faculty Presentation 1: Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma — Dr Christopher Flowers

    CME information and select publications


    Hodgkin and Non-Hodgkin Lymphomas | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Hodgkin and Non-Hodgkin Lymphomas Feb 18, 2023
    Show notes

    Featuring perspectives from Drs Christopher Flowers and Laurie Sehn, including the following topics:

    • Introduction (0:00)

    • Treatment for Diffuse Large B-Cell Lymphoma (7:45)

    • Management of Hodgkin Lymphoma (35:33)

    • Follicular Lymphoma (41:57)

    • Caring for Patients with Mantle Cell Lymphoma (51:38)

    CME information and select publications


    Thyroid Cancer and Neuroendocrine Tumors | Oncology Today with Dr Neil Love — Thyroid Cancer and Neuroendocrine Tumors Feb 15, 2023
    Show notes

    Featuring perspectives from Drs Jonathan Strosberg and Lori Wirth, including the following topics:

    • Nontargeted Treatment for Thyroid Cancer
      • Introduction (0:00)
      • Case: A woman in her late 60s with poorly differentiated thyroid cancer initially treated with lenvatinib – Dr Wirth (6:05)
    • NTRK Fusions in Thyroid Cancer
      • Case: A woman in her early 60s with metastatic papillary thyroid cancer with an NTRK fusion who received repotrectinib – Eric Sherman, MD (13:27)
      • Case: A man in his early 60s with metastatic papillary thyroid cancer with NTRK fusion who received larotrectinib – Dr Wirth (18:37)
    • RET Mutations/Fusions in Thyroid Cancer
      • Case: A man in his early 40s who presents with metastatic medullary thyroid cancer with a RET mutation – Dr Sherman (21:43)
      • Case: A man in his early 40s with metastatic medullary thyroid cancer with a RET mutation who received selpercatnib – Dr Wirth (27:49)
    • Somatostatin Analogs for Neuroendocrine Tumors (NETs)
      • Case: A woman in her early 50s with a newly well-differentiated small-bowel NET and low-volume liver metastases – Pamela Kunz, MD (33:41)
    • Management of Carcinoid Syndrome with NETs
      • Cases: A man in his early 60s with a well-differentiated small-bowel NET with stable disease on octreotide who is now experiencing increasing diarrhea and a man in his early 60s who received telotristat ethyl for carcinoid syndrome diarrhea – Dr Kunz and Dr Strosberg (41:25)
    • Von Hippel-Lindau-Associated Pancreatic NETs
      • Case: A woman in her late 40s with von Hippel-Lindau syndrome and a pancreatic NET who received belzutifan – Dr Strosberg (49:42)
      • Case: A man in his early 60s with a symptomatic, well-differentiated hypervascular pancreatic NET with bulky liver metastases – Dr Kunz (55:38)

    CME information and select publications


    Multiple Myeloma | Meet The Professor: Optimizing the Management of Multiple Myeloma — Part 4 Feb 14, 2023
    Show notes

    Featuring perspectives from Dr Noopur Raje, including the following topics:

    • Introduction (0:00)

    • Case: A man in his early 80s who presents with renal failure (creatine = 7) and standard-risk multiple myeloma (MM) — Swati Vishwanathan, MD (14:22)

    • Case: A man in his late 60s with a large sternal plasmacytoma — Warren S Brenner, MD (20:35)

    • Case: A man in his early 60s who presents with multiple bone lesions and t(4;14), (1q21+) MM — Hans Lee, MD (23:21)

    • Case: A man in his late 30s with standard-risk MM who receives RVd followed by autologous stem cell transplant and has been on maintenance lenalidomide for 3.5 years — Yanjun Ma, MD (32:32)

    • Case: An asymptomatic woman in her mid 60s with quadruple-refractory MM with multiple prior serious infections — Neil Morganstein, MD (40:38)

    • Faculty Survey (53:19)

    • Case: A woman in her mid 70s with MM who developed severe peripheral neuropathy from induction RVd — Ranju Gupta, MD (57:45)

    CME information and select publications


    Non-Small Cell Lung Cancer | Oncology Today with Dr Neil Love: Management of Metastatic Non-Small Cell Lung Cancer without an Actionable Mutation (Companion Faculty Lecture) Feb 13, 2023
    Show notes

    Featuring a slide presentation and related discussion from Dr Edward Garon, including the following topics:

    • Immune checkpoint inhibitor therapy for treatment-naïve advanced non-small cell lung cancer (NSCLC) without an actionable mutation (0:00)

    • Duration of immunotherapy in the frontline setting for NSCLC with no targetable mutation (13:43)

    • New treatment strategies for relapsed or refractory NSCLC with no targetable mutation (16:25)

    • Management of antibody-drug conjugate-associated toxicity (19:08)

    • Activity of antibody-drug conjugates alone or in combination with anti-PD-1 antibodies (26:18)

    CME information and select publications


    Non-Small Cell Lung Cancer | Oncology Today with Dr Neil Love: Management of Metastatic Non-Small Cell Lung Cancer without an Actionable Mutation Feb 13, 2023
    Show notes

    Featuring an interview with Dr Edward Garon, including the following topics:

    • Treatment of non-small cell lung cancer (NSCLC) today versus prior to the availability of immune checkpoint inhibitors (0:00)
    • Current and emerging roles of antibody-drug conjugates in NSCLC (3:30)
    • Optimal workup for patients presenting with metastatic NSCLC; role of biomarker assessment (5:02)
    • Considerations for the addition of an anti-CTLA-4 antibody to the treatment regimen for NSCLC (17:30)
    • Correlation between immune-related toxicity and the efficacy of immune checkpoint inhibitors (21:47)
    • Case: A woman in her mid 60s with multiple comorbidities presenting with NSCLC with a KRAS G12A mutation, pleural effusion and extensive bone metastases (24:35)
    • Case: A man in his mid 50s with a long smoking history presenting with squamous cell carcinoma of the lung (31:07)
    • Case: A woman in her early 60s with NSCLC with an EGFR L858R mutation who is relapsing after treatment with multiple therapies (37:22)
    • Language barriers leading to disparities in clinical trial enrollment (44:38)

    CME information and select publications


    Myeloproliferative Neoplasms | Oncology Today with Dr Neil Love: Key Presentations on Myeloproliferative Neoplasms from the 2022 ASH Annual Meeting Feb 09, 2023
    Show notes

    Featuring perspectives from Dr Srdan Verstovsek, including the following topics:

    • Overview of current issues in the management of myeloproliferative neoplasms (MPN) (0:00)
    • Treatment strategies for patients with myelofibrosis (MF) progressing after ruxolitinib (14:46)
    • Correlation of molecular characterization and response to ruxolitinib in patients with MF (23:57)
    • Rationale for and efficacy with combined inhibition of Bcl-2 and Bcl-xL for MPN (44:38)
    • Targeting calreticulin mutations for MPN (52:02)
    • Advances in the management of polycythemia vera (57:54)
    • Developments in the care of patients with essential thrombocythemia (1:04:43)
    • Future directions in the clinical care of patients with MPN (1:12:46)

    CME information and select publications


    Gynecologic Oncology | Krishnansu S Tewari, MD Feb 08, 2023
    Show notes

    Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Gynecologic Oncology — Faculty Presentation 2: Endometrial and Cervical Cancer — Dr Krishnansu Tewari

    CME information and select publications


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