Real Life Pharmacology &#8211; Pharmacology Education for Health Care Professionals

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Food and Supplement Drug Interactions May 16, 2024

Show notes

On this episode of the Real Life Pharmacology Podcast, I cover some of the most common food and supplement drug interactions.

The 3 G’s can potentially increase the risk of bleeding in patients on anticoagulants and antiplatelets. I discuss what supplements these are.

There are some vitamins that can cause drug interactions. Vitamin C is a supplement that can alter the absorption of some medications.

Metal cations like iron can bind certain medications and reduce absorption. I discuss which medications are most likely to be affected.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Vonoprazan Pharmacology – New Esophagitis Medication Class! Episode 326 May 09, 2024

Show notes

On this episode, I discuss the new medication vonoprazan and where it will likely be used in practice.

Vonoprazan is from a brand new class of medication called “PCAB”. I discuss this medication and its pharmacology in this podcast episode.

Drug interactions and cost are the two major downsides of this medication that will likely limit its use compared to the PPIs.

CYP3A4 inducers like rifampin, carbamazepine, and phenytoin should not be used with vonoprazan. They will reduce the effectiveness of vonoprazan.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

10 Commandments of Polypharmacy Part 2 of 2 May 02, 2024

Show notes

Today’s sponsor of the 10 Commandments of Polypharmacy podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you.

FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use the discount code: RLPPOD

Here is part 2 of 2 on the final 5 of the 10 commandments of polypharmacy.

6. Thou shalt identify limits for medications not intended for chronic use as well as not continue a medication indefinitely for symptoms that have an expected short duration

7. Thou shalt not start a medication from a similar medication class without appropriate rationale

8. Thou shalt not initiate a medication without considering medications that may treat duplicate conditions – Kill two birds with one stone

9. Thou shalt consider eliminating or reducing medications at every medication review

10. Thou shalt be willing to accept risk in discontinuing a medication if they were willing to accept the risk of initiating a medication

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Ten Commandments of Polypharmacy – Part 1 Apr 25, 2024

Show notes

On this special episode, I provide some real-life examples and layout 5 of my 10 commandments of polypharmacy.

Today’s sponsor of the 10 Commandments of Polypharmacy podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you.

FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use the discount code: RLPPOD

Here are the first 5 commandments that are addressed in the podcast.

1. Thou shalt not start, ask for, dispense, or administer medication without reviewing a medication list that is accurate, up to date, and complete with over-the-counter medications and supplements

2. Thou shalt consider utilizing non-drug approaches and interventions to solve patient problems before initiating medication

3. Thou shalt assess if a medication is effective before adding a new medication for the same condition

4. Thou shalt consider any new symptom is an adverse effect of another medication until proved otherwise

5. Thou shalt not start a medication without an appropriate indication and assessing appropriate lab work

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Top 10 Anticoagulant Drug Interactions Apr 18, 2024

Show notes

Today’s sponsor of the Top 10 Anticoagulant Drug Interactions podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you.

FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use the discount code: RLPPOD

Apixaban is one of the most commonly used anticoagulants and there are some drug interactions you need to be aware of. Take a listen and find out!

Warfarin concentrations can substantially be elevated by drugs that inhibit CYP2C9. I cover a few of them in my top 10 anticoagulant drug interactions.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Top 10 SSRI Drug Interactions Podcast Apr 11, 2024

Show notes

Today’s sponsor of the Top 10 SSRI Drug Interactions podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you.

FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use the discount code: RLPPOD

In this podcast episode, I discuss how to navigate SSRI drug interactions and identify some of the most common medications that have additive serotonergic activity.

SSRIs have antiplatelet activity. I discuss how to navigate using other medications that may increase bleed risk in combination with SSRIs.

Paroxetine and fluoxetine inhibit CYP2D6 I discuss how this can affect the benefits of tamoxifen therapy.

Fluvoxamine is a nasty medication with regard to the number of and significance of drug interactions. I outline important fluvoxamine interactions in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Travoprost Pharmacology Apr 04, 2024

Show notes

On this episode, I discuss travoprost pharmacology, adverse effects, administration, and much more on this podcast episode.

Travoprost is used to reduce intraocular pressure in the management of glaucoma. I discuss the mechanism of action and adverse effects.

Travoprost is a prostaglandin analog that can help reduce intraocular pressure and reduce the risk of the potential complication of blindness.

Growth of eyelashes is a unique adverse effect associated with travoprost.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Beers Criteria Podcast Part 2 or 2 Mar 28, 2024

Show notes

On this podcast episode, I finish up my breakdown of the Beers Criteria.

I cover the use of sliding-scale insulin and sulfonylureas in geriatric patients. Hypoglycemia is a major concern with both of these diabetes management strategies.

PPIs show up on the Beers criteria list as they can increase the risk of C. diff, pneumonia, fractures, and GI malignancies.

Metoclopramide has dopamine antagonist activity and can increase the risk of EPS and tardive dyskinesia.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Beers Criteria Podcast Part 1 or 2 Mar 21, 2024

Show notes

In this podcast episode, I break down some of the most common medications that show up on the Beers criteria list.

I discuss cardiovascular medications in this podcast episode, including rivaroxaban and warfarin, and why they show up on the Beers list.

Alpha-blockers who up on the Beers list as these medications are inappropriate to use for the management of hypertension.

The Beers criteria addresses the use of aspirin in primary prevention. I break down what the criteria state and why it should be avoided in general.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)