Rapid Response

Latest Episodes:

Resurrecting dire wolves is just the beginning for Colossal Biosciences’ Ben Lamm Dec 23, 2025

Show notes

In this encore episode of Rapid Response, we revisit a scientific breakthrough that set the internet ablaze: The ‘de-extinction’ of the dire wolf. While many celebrated Colossal Biosciences’ announcement, the experiment also sparked controversy throughout the scientific community — namely the ethics of birthing and re-wilding extinct animals, and whether Colossal’s dire wolf puppies are the real thing. Colossal’s co-founder and CEO Ben Lamm joined Rapid Response to take us inside the dire wolf journey, revealing how the startup attracted a roster of celebrity investors, and what the company’s technology means for not only conservation and biodiversity, but potentially the future of human health.

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AI in 2026: hype, whiplash, and… home robots? with Dr. Rana El Kaliouby Dec 19, 2025

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How should leaders prepare for AI’s accelerating impact on work and everyday life? AI scientist, entrepreneur, and Pioneers of AI host Dr. Rana El Kaliouby returns to Rapid Response to share her predictions for the year ahead — from physical AI entering the real world to what it means to onboard AI into your org chart. El Kaliouby also cuts through today’s biggest AI headlines, including the chatbot arms race, Instacart’s dynamic pricing controversy, and whether we’re really living through an AI bubble.

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Lessons of Rapid Response for 2026 Dec 16, 2025

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This year delivered whiplash: geopolitics, tariffs, and technology all shifting at once. And heading into 2026, the disruption isn’t easing up. In this special episode, host Bob Safian distills five hard-won lessons from Rapid Response this year on how to lead when the ground won’t stop moving. You’ll hear standout moments from Brian Chesky, Clara Shih, Marc Lore, José Andrés, and more, with practical takeaways for turning uncertainty into advantage.

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Can philanthropy rescue local journalism? Dec 12, 2025

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When the U.S. government cut funding for local news stations, the Knight Foundation moved quickly to help stabilize a rapidly eroding industry. President and CEO Maribel Pérez Wadsworth joins Rapid Response to unpack the evolving roles of philanthropy and government, and why philanthropic organizations must learn to move at the speed of the news cycle. Wadsworth also explores what traditional journalists can learn from digital creators, the risks of crossing political leaders, and how to stay impartial in an increasingly polarized environment.

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Kara Swisher takes on big tech, from Apple to Nvidia Dec 09, 2025

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Can ChatGPT dethrone Gemini? Is Tim Cook capable of leading Apple into the next wave of AI? As 2025 winds down, journalist and podcast host Kara Swisher joins Rapid Response to cut through the noise and decode what’s really happening across OpenAI, Meta, Google, and more. Swisher also sizes up the state of Disney, Netflix, and the escalating bidding war for Warner Bros. Discovery. And in classic Swisher fashion, she doesn’t hold back — weighing in on Elon Musk’s eye-popping potential pay package, Mark Zuckerberg’s costly misfires at Meta, and what the future of AI means for human health and cognition.

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Hollywood’s AI rampage, with The Ankler’s Janice Min Dec 05, 2025

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Is Hollywood truly prepared for the existential threat AI poses? The Ankler CEO Janice Min returns to Rapid Response to dissect AI’s seismic impact on the entertainment industry — from “synthetic performances” and collapsing production jobs to the buzz around OpenAI’s animated film, Critterz. Min also weighs in on the brewing Warner Bros. Discovery bidding war, Netflix’s expansion into video podcasts, and Disney’s high-stakes standoff with YouTube.

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Embrace the multihyphenate career, with Chief’s Alison Moore Dec 02, 2025

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A recent New York Times headline — “Did Women Ruin the Workplace?” sparked a firestorm across social media. Bob Safian welcomes a leader pushing back on this notion with data and nuance: Alison Moore, CEO of Chief, the prestigious network for senior women executives. Drawing from an exclusive nationwide survey of women leaders, Moore unpacks how evolving career paths are being misread, why women-centered spaces remain vital, and the rise of the multihyphenate leader. As a former HBO executive, Moore also reveals how she’s applying lessons from Game of Thrones to Chief, and how she stays attuned to the cultural pulse, from AI to shifting leadership expectations.

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Labubu, FOMO, and the live shopping boom, with Whatnot’s Grant LaFontaine Nov 28, 2025

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While digital live shopping has been popular for years in Asia, the phenomenon has only recently begun to take off in the U.S., thanks in large part to the rise of retail disruptor Whatnot. The platform’s co-founder and CEO, Grant LaFontaine, joins Rapid Response to share how his team has managed to evoke the feel of in-person shopping inside an online experience, why he weighs “fun” versus FOMO as a customer-engagement tool, and how Whatnot’s breakthrough is influencing other retailers and brands. LaFontaine also digs into the startup’s response to deep-pocketed rivals like eBay, and why he believes the viral Labubu trend is here to stay.

This episode is brought to you by Stripe.

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Beyond the Parade: Macy’s navigates tariffs, turbulence and retail evolution Nov 25, 2025

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This Thursday marks the 99th annual Macy’s Thanksgiving Day Parade, and Macy’s Inc. chairman and CEO Tony Spring joins Rapid Response with a behind-the-scenes preview of what to expect. It’s been a tumultuous year for the legacy retailer, shaped by new tariffs, shifting consumer habits, and the constant flip between “wartime” and “peacetime” leadership. Spring shares why his team is now on “version twenty-seven of the plan,” how Macy’s is entering the AI era, and what it really means to court the next generation of shoppers while staying grounded in “balance, not hype.”

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Rebuilding American courage and character, with General Stanley McChrystal and Baratunde Thurston Nov 21, 2025

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What does it mean to be a courageous leader in 2025? Former U.S. General Stanley McChrystal joins futurist and culture critic Baratunde Thurston on stage at Masters of Scale Summit in San Francisco to discuss the responsibility of leaders today, the importance of character, and the weight of being an active citizen in democracy. Considering President Trump’s deployment of the National Guard, McChrystal explores the role of the military in civil society, and how the military is poised to evolve in the wake of AI.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

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