Peptide of the Week| Weight Loss, Health & Wellness

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**Peptide of the Week| Weight Loss, Health & Wellness**

Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.

Latest Episodes:

Back From China: The Truth About Peptide Sourcing + BPC-157 Questions | Peptide of the Week Q&A #66 Nov 12, 2026

Show notes

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

JD Denham and William T. Haas are back from China and open the show with what they saw, why all raw peptide API comes from China, and why so many people end up with underdosed or fake product. They also share big news: JD's wife is pregnant, and they break down the fertility protocols that worked. Then it's a BPC-157 themed Q&A covering a 20 year old ulcer, rotator cuff surgery recovery for a 62 year old, joint pain at 98 days sober, Hashimoto's and autoimmune RA, and digestion after gallbladder removal. They also preview the mold detox and EBOO series, the new hyperbaric chamber, Trevor Kruder breaking down the China trip, and a possible run of bonus gear episodes.

🔬 Topics Covered

• Why every raw peptide starts in China and why it cannot be made in the USA

• Why about 75% of peptides bought direct from China are underdosed, fake or contaminated

• JD's wife is pregnant: the HCG and Klotho protocol he was running and what Will recommends for fertility

• Can one bottle of BPC-157 pills heal a stomach problem you have had for 20 years?

• Rosacea and dandruff that never go away: the gut bug that may be behind both

• Torn rotator cuff with titanium screws: the triangle injection method and how much Wolverine to use

• The 5 day post-surgery BPC and TB-500 protocol JD ran after his back surgery

• Sore knees, wrists and shoulders at 37 and 98 days sober: what is really going on

• Hashimoto's, hypothyroidism and autoimmune RA: where peptides fit and where they do not

• Mold detox, EBOO, hyperbaric and bonus gear episodes: what is coming next

Chapters:

00:00 – Intro

00:09 – Welcome Back & Will's Name Twin

00:51 – Upcoming Mold Expert & EBOO Blood Cleaning

03:02 – Hyperbaric Chambers: Longevity & Healing

09:08 – Gear Podcast Bonuses & Upcoming Guests

11:52 – China Trip Follow-Up: Raw API vs. Finished Vials

13:07 – Why 75% of Chinese Peptides Fail & Your Risk Tolerance

16:58 – Big News & Fertility Protocols: HCG, Enclomiphene & HMG

26:18 – Today's Compound: How BPC-157 Was Discovered

30:34 – Q&A: BPC & KPV Pills for a 20-Year Stomach Ulcer

36:39 – Q&A: Rotator Cuff Surgery Recovery Stack

44:31 – Q&A: Sore Joints & Tendons at 37 (98 Days Sober)

52:39 – Q&A: Hypothyroidism, Hashimoto's & Autoimmune Stack

1:00:50 – Q&A: BPC & KPV After Gallbladder Removal

1:02:12 – Outro: Skool Community & Feedback Request

Fake Naturals & Deadly Gear Trends with Alex Diago Pt. 1 | Peptide of the Week Podcast Nov 09, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Follow Alex Diago:

Instagram: https://www.instagram.com/diagofit

E-Book: https://diagofit.com/e-book

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Fitness and enhancement coach Alex Diago, known for calling out fake naturals, joins JD Denham and William T. Haas for a raw conversation about gear. He shares how he went from jail to building a massive platform, the mistakes that nearly wrecked him, and why he believes the current wave of extreme social media enhancement is heading somewhere dark. This is part one of two.

🔬 Topics Covered:

• Alex's story: from a skinny 120 pound kid to jail to coaching

• How one viral acne reaction video launched his brand

• Why fake naturals are everywhere and how the marketing works

• Breaking down what a top Olympia level cycle likely looks like

• Why Alex says golden era Arnold is the physique to aspire to

• How cycles climbed from 300mg to 3 to 5 grams per week

• What happens when you stack Tren, orals, and a gram of gear

• The danger of TikTok kids pushing insulin, diuretics, and DNP

• Why Alex says test and growth hormone is all most guys ever need

• Where total testosterone should be: 800 to 1,000 for optimal performance

• Why your first labs should be before the cycle, not a month in

• Pre, mid, and post cycle blood work explained

• What real TRT looks like and why needing an AI means it's a cycle

• Test C vs Test E: why they are the same compound

• Why beginners should never run a test blend or Sustanon

• Half lives, PCT timing, and why most guys start recovery too early

Chapters:00:00 – Intro

00:09 – Welcome & Meet Alex Diago

02:18 – Rebel Years, Jail & Discovering Gear

04:21 – Going Viral With Gear Content

07:22 – Why Fake Naturals Exist & Mike O’Hearn

13:27 – Olympia Insulin Seizure, DNP & Rage Bait Kids

20:28 – Toxic Dosing: A Gram of Tren & Pinning Daily

23:20 – Best Cycle Advice: Just Test & Growth Hormone

26:02 – Alex’s First Cycle: Everything Done Wrong

32:00 – What Counts as TRT vs. a Cycle

34:54 – Anastrozole vs. Letrozole & Test C vs. E

38:38 – Half-Lives, Blends & Starting PCT Correctly

41:43 – Misinformation, TikTok Bro Science & Research Compounds

46:07 – The Dangerous TikTok Crowd & Peptides’ Bad Name

50:20 – Outro

We Went Inside China’s Billion Dollar Peptide Factories (Here’s What We Saw) | Peptide of the Week Nov 05, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Everyone asks where peptides are really made and whether China is bad. JD Denham and William T. Haas recorded this bonus episode live from Guangzhou, China, after spending a week touring tier one manufacturing facilities, sitting in boardrooms with top executives, and walking the world's largest trade fair. Here is what they saw, what surprised them, and why their opinions changed.

🔬 Topics Covered:

• Why we flew to China and what we were looking for

• Where peptides are actually made and why it matters

• What an API is and how raw powder becomes the vial you inject

• The unwritten US and China agreement: China makes the raw materials, the US finishes the product

• Why America can't make raw peptides at scale (hint: EPA standards)

• Inside billion dollar facilities with 15 analytical labs and strict quality control

• Sitting in the boardrooms of two of the largest peptide manufacturers in the world

• Why Chinese business runs on relationships and how one bad dinner can cancel a contract

• Why compounds like Klotho and FLGR-242 are nearly impossible to test independently right now

• The Canton Fair: 75,000 booths vs 184 at Mr. Olympia

• Our biggest fears going in and what we actually found

• Why we think the people are kinder and more respectful than we expected

• Language, trash cans, squat toilets, and other culture shocks

• Why China may have beaten Prague as our favorite trip

• How two guys from a garage went from a pipe dream to a business trip in China

Chapters:

00:00 – Intro & Welcome Back From Guangzhou

00:29 – The Lost AirPods & Translation Headphones

02:18 – Language Barrier: Cantonese vs. Mandarin

04:04 – Why There Are No Trash Cans in China

07:56 – Why We’re in China: Sourcing Raw Peptide APIs

09:18 – How the US–China Peptide Supply Chain Works

10:45 – Touring Tier-One Manufacturing Facilities

14:14 – Doing Business in China: Relationships & Dinners

16:06 – Why Testing New Peptides Is So Hard

18:40 – The Canton Fair: 75,000 Booths

21:13 – What China Is Really Like: First Impressions

25:46 – Heat, Halloween Night & Getting Lost in a Taxi

30:49 – You Can Do It Too: Mindset & Work Ethic

34:06 – Why We Share Everything & Industry Camaraderie

37:00 – Outro

We Tried FLGR-242 & Klotho: The Honest Truth | Peptide of the Week Podcast Nov 04, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

After two episodes with the inventor, JD Denham and William T. Haas break down FLGR-242 and Klotho from their own experience. JD has run FLGR-242 for two and a half months, they both have Klotho in their stack, and they give you the real results, the side effects nobody is talking about, and the one overdose warning you need to hear before you inject.

🔬 Topics Covered:

• Why FLGR-242 is the first peptide people say can rival gear

• Myostatin explained: your body's built-in brake on muscle growth and fat burning

• FLGR-242 vs Follistatin-344 and why selectivity matters

• The albumin binder: how it makes these compounds last for weeks

• Claimed results of 10 to 14 pounds of muscle in 3 to 4 months

• JD's honest 2.5 month review, including the extreme hunger

• Why the hunger can't be timed around a once a week injection

• FLGR-242 dosing: 5mg per week for men, about 2.5mg for women

• Why going above 10mg per week shows diminishing returns

• FLGR-242 vs gear: where it lands compared to Anavar and Winstrol

• What Klotho does for your kidneys and why EGFR matters

• How you know Klotho is working: frequent urination and clear urine

• Klotho's reported effects on sex drive, bone health, and blood pressure

• The big Klotho warning: overdosing acts like an uncontrolled diuretic

• Klotho dosing: 10mcg every two weeks, and never more

• Why they are being cautious: brand new compounds with no controlled human studies

• Blood work first: JD's plan to test off everything before restarting

Chapters:

00:00 – Intro

00:09 – Welcome Back & China Trip Logistics

00:49 – Chinese Business Etiquette: What Not to Do

02:49 – Jet Lag & What to Expect in China

07:55 – Mom's Move & the Dog Debate

14:40 – Today's Compounds: FLGR-242 & Clotho

17:48 – Does FLGR-242 Rival Gear? Modified Follistatin Explained

21:11 – Belgian Blue Cows & Muscle-Sparing Benefits

26:52 – JD's Experience: Hunger & Real Results

29:53 – FLGR-242 Dosing for Men & Women

33:28 – Unknowns, Risks & Your Risk Tolerance

38:00 – Clotho: Kidney Function & Longevity

43:12 – How You Know Clotho Is Working

46:26 – Clotho Dosing & the Diuretic Warning

50:14 – Closing Thoughts & China Trip Outro

Is Your Testosterone Actually Optimized? The TRT Deep Dive | Peptide of the Week Q&A #65 Nov 04, 2026

Show notes

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

JD Denham and William T. Haas go all in on a dedicated TRT episode covering five of the most common hormone questions they get. From a 21-year-old with great total testosterone but terrible free test, to a guy down 115 pounds wondering if he even needs TRT, to the real answer on ball shrinkage and what HCG actually does about it. Plus Dave Palumbo and Alex Diego are coming on the podcast soon and JD announces the upcoming gear deep dive episode.

🔬 Topics Covered

• 21-year-old with total T of 970 but free test of only 5.6: what is actually going on and what to do about it

• Why fasting too hard and eating too little is silently killing your free testosterone at any age

• Down 115 pounds at 43 with total T of 635: can you actually be hormonally optimized without TRT?

• What does hormone optimization actually mean and why does every single peptide work better when you are there

• Why low testosterone is probably behind your anxiety, brain fog, depression and lack of sex drive and not just aging

• Is 1200 total testosterone too high and is 800 too low: the real answer for a 56-year-old on TRT

• Total testosterone is only a quarter of the picture: why free T, estrogen, SHBG and LH tell the real story

• Ball shrinkage on TRT: is it real, how bad does it get, and what does HCG actually do about it

• Should a 44-year-old switch from CJC and Ipa to actual HGH and should he start TRT based on blood work alone

• Why 10,000 steps a day is a lot harder than you think and why walking after every meal changes everything

Chapters:

00:00 – Intro

00:09 – Welcome Back & Hawaii Recap

00:39 – China Trip & Why Addicts Can Do Big Things

03:44 – Finding Your Path & Becoming a Student of Your Craft

07:22 – New Q&A Format: Structured TRT Questions

08:19 – Q&A: High SHBG & Low Free Testosterone at 21

15:57 – Q&A: Should a 48-Year-Old With 582 Total T Start TRT?

20:48 – The 10,000 Step Reality & Post-Meal Walks

25:43 – Q&A: What Does Hormone Optimization Actually Mean?

33:14 – Signs of Low Testosterone & Benefits of Optimizing

38:15 – Upcoming Guests: Palumbo, Alex Diego & a Mold Specialist

42:10 – Q&A: What Is the Optimal TRT Level at 56?

46:15 – Total vs. Free Testosterone: The Bank Account Analogy

47:58 – Q&A: Testicular Shrinkage on TRT & HCG

56:15 – Outro: Gear Episode Plans & Coaching Program

FLGR-242 – The Muscle Building Compound That’s Changing Everything Pt. 2 | Peptide of the Week Pod Nov 04, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Part two with Michael Farber goes deep on FLGR-242, the long acting myostatin inhibitor he invented that is helping people gain 10 to 12 pounds of lean muscle in three to four months, without anabolics, without side effects, and regardless of genetics. This is one of the most important muscle building conversations we have ever had on this podcast.

🔬 Topics Covered:

• Why Farber invented FLGR-242 after losing 2+ years of muscle during COVID

• What myostatin actually is and why it is your body's brake on muscle growth and fat burning

• Belgian blue cows, super mice, and real world examples of myostatin mutations

• Why naturally gifted athletes often have partial myostatin mutations and do not even know it

• How FLGR-242 levels the playing field for people not born with athletic genetics

• Expected results: 10 to 12 pounds of lean muscle in 3 to 4 months at 5mg per week

• Why going above 10mg per week produces virtually no additional gains

• Farber personally went to 20mg per week and confirmed no negative health effects above 10mg

• How FLGR-242 was designed to bind ONLY myostatin and why that makes it so safe

• Why Follistatin-344 causes random growth and must be injected locally while FLGR-242 freely circulates

• Brian Johnson's myostatin experiment in Honduras: 2% gain in a year at $50,000 per try

• FLGR-242 vs circular DNA myostatin inhibitors: not even close

• Apelin-13: the ergogenic compound that optimizes fat burning and cardiovascular output simultaneously

• Long acting Thymosin Alpha-1 and Thymosin Beta coming soon

• Bioline: the new appetite and metabolism compound coming down the pipeline

• The albumin binder platform and why it is changing how every compound performs

Chapters:

00:00 – Intro

00:09 – Welcome Back & Will's Mom Moving to Town

01:24 – Appreciating Your Parents While You Have Them

03:29 – Round Two With Michael Farber: Why He Created FLGR-242

06:27 – Myostatin Inhibition Beyond Muscle: Obesity & Fetal Growth

10:02 – Leveling the Playing Field for Natural Athletes

12:21 – Real-World Results: 10–12 Pounds of Lean Muscle in 4 Months

14:44 – Dosing: Why More Than 10 mg a Week Doesn't Help

19:23 – How FLGR-242 Differs From Follistatin 344

24:06 – Safety Record & Gene Therapy Alternatives

27:55 – What's Next: Apelin, Long-Acting Thymosin & Obesity Compounds

30:16 – The Albumin Binder Discovery: MC4R & Amylin Compounds

34:34 – Cancer Drug Trojan Horse Idea

36:40 – Upcoming Launches: Appetite Control & Long-Acting Thymosin Alpha-1

38:44 – Outro

HGH Morning or Night? The Answer Nobody Is Getting Right | Peptide of the Week Q&A #64 Nov 04, 2026

Show notes

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

JD Denham is live from Maui on his honeymoon while William T. Haas holds it down in the studio. This week they go deep on growth hormone in all its forms covering HGH timing for normal vs reduced pituitary function, whether stacking Tesamorelin on top of HGH is a waste of money, how to run your first steroid cycle properly, why FLGR 242 is the first compound JD says can genuinely compete with gear, and what carpal tunnel symptoms after adding Ipamorelin actually mean.

🔬 Topics Covered

• Why taking HGH at night could be silently sabotaging your biggest natural growth hormone pulse

• Is stacking Tesamorelin on top of HGH a waste of money or does it still do something unique?

• Carpal tunnel and joint pain after adding Ipamorelin at only 200mcg: bad sign or great sign?

• Running your first steroid cycle with Test and Primo: why stopping at 8 weeks is the worst mistake you can make

• Should you add FLGR 242 or IGF-1 LR3 to a steroid cycle and what actually happens when you do?

• Why taking HGH on workout days only and skipping rest days is completely backwards

• MK-677 vs Ipamorelin: why one will make you eat everything in sight and the other probably won't affect your hunger at all

• Can you stack HGH, MK-677 and IGF-1 LR3 together or is that just overkill?

• Why Klotho may be the most underrated compound for anyone running gear and what it is actually doing for your kidneys

• Every single person listening should be taking glutathione and here is exactly why

Chapters:

00:00 – Intro

00:09 – Welcome Back & Live From Maui

01:49 – Why Vacation and Rest Matter

03:20 – How Muscle Actually Grows: Recovery & HGH Timing

04:58 – Training Intensity, Dorian Yates & Muscle Group Splits

11:12 – Steroids Don't Replace Hard Work

13:49 – Why Legs, Back & Deadlifts Matter

17:10 – China Trip & Shoutout to the Team

18:35 – Buying a Whole American Wagyu Cow

22:01 – Q&A: HGH vs. Secretagogues for a 34-Year-Old Woman

28:46 – Q&A: Ipamorelin Carpal Tunnel & Joint Pain

34:19 – Q&A: Stacking HGH With Tesa, Ipa & Sermorelin

41:35 – Q&A: Peptides While Running Test & Primo

56:10 – Q&A: HGH, MK-677 & IGF-1 LR3 Timing

1:03:11 – Q&A Format Feedback, Skool & Outro

The Man Who Invented Klotho & FLGR-242 – Michael Farber Pt. 1 | Peptide of the Week Podcast Nov 04, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

This is not a conversation about peptides. This is a conversation with the man who invented two of the most talked about longevity compounds on the planet. Dr. Michael Farber joins JD Denham and William T. Haas to break down Klotho and FLGR-242 from the ground up. Who created them, why he created them, how they actually work in the body, and where medicine is heading in the next 20 years.

🔬 Topics Covered:

• Who is Dr. Michael Farber and his 35 years in biochemistry and 150 patents

• Why he invented Klotho to save his own kidney after losing his right kidney in his teens

• How Klotho regulates phosphate and calcium and why that matters for kidney function

• The feedback loop of kidney disease that has never been reversible until now

• People going from an EGFR of 40 back up to 70 and beyond on Klotho

• Why Klotho makes NAD work dramatically better through the SIRT1 pathway

• Klotho and the blood brain barrier: clearing toxic plaque buildup without entering the brain

• Why Dr. Farber considers Klotho more important for longevity than FLGR-242

• How the albumin binder platform works and why it allows bi-weekly dosing

• Klotho dosing: 10 micrograms every two weeks for healthy individuals, every 11 to 12 days for kidney dysfunction

• What happens if you overdose Klotho and why it is strictly range-bound

• FLGR-242: the long-acting myostatin inhibitor that is outperforming all expectations

• Why FLGR-242 dosing is nothing like Follistatin-344 and must not be confused

• The future of medicine: synthetic organs, CRISPR, fetal genetic optimization, and living to 120

• Dr. Farber consumed a bottle of painkillers a week for decades. In the last 18 months he has taken two or three total.

Chapters:

00:00 – Cold Open: Living With Kidney Disease for 40 Years

00:45 – Intro

00:54 – Welcome Back & Meeting Dr. Michael Farber

02:50 – Why He Created Klotho: Losing a Kidney

05:10 – Klotho Results: 10 mcg & Rising eGFR

07:34 – The Albumin Binder Breakthrough

12:28 – How Klotho Works in the Body

14:53 – Klotho, NAD+ & FLGR-242 Synergy

20:13 – Cardiovascular Health & Restored Libido

21:54 – Klotho Dosing: 10 mcg Every 11–14 Days

24:52 – Separating Hype From Reality

27:14 – Overdose Risks & Checking Urine Output

29:42 – Feeling “Reborn”: Life After Kidney Disease

36:30 – The Future of Longevity: Organs & CRISPR

45:12 – Outro & Part 2 Preview

Should You Ever Stop Taking R? The Truth About Long Term Use | Peptide of the Week Q&A #63 Nov 04, 2026

Show notes

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

JD Denham and William T. Haas sit down for a focused all-R episode covering the most common questions they get about "R". From whether you actually need to stop between cycles, to building a stack from scratch as a brand new female, to using R with breast cancer history, to whether Cagrilintide is worth bridging with over the holidays. Plus Dr. Mike Farber, creator of FLGR 242 and Klotho, is coming on the podcast next week and JD has been running FLGR long enough to say it is giving gear a serious run for its money.

🔬 Topics Covered

• Do your R receptors actually burn out and do you need to cycle off?

• The best way to time your R doses around the weekend when cravings hit hardest

• Building a peptide stack from absolute zero as a 33-year-old female athlete

• Why taking too many peptides at once is costing you money and answers

• Hormone breast cancer history on R: what is safe and what is not

• Why fatigue on R almost always comes down to one thing nobody wants to hear

• AOD vs Tesamorelin vs HGH for a 45-year-old male trying to lose his last 20 pounds

• Does 5-Amino-1-MQ actually block NAD or is that completely backwards?

• The cognitive and fat burning stack for a 40-year-old Marine on TRT and R

• FLGR 242 is the first peptide JD says is genuinely giving gear a run for its money

Chapters:

00:00 – Cold Open: Should You Stop "R"?

01:00 – Intro

01:09 – Welcome Back & VIP Zoom Call Updates

03:44 – Website, Trusted Sources & Coaching Updates

04:59 – Upcoming Guest: Dr. Mike Farber (FLGR-242 & Clotho)

08:21 – Q&A: Bridging Between "R" Cycles With Cagrilintide

15:24 – Q&A: Building a Peptide Stack as a Beginner

28:22 – Q&A: Low Energy on Reta After Breast Cancer

38:22 – Q&A: AOD-9604 & CJC After Major Weight Loss

46:18 – Q&A: Do 5-Amino-1MQ & NAD+ Conflict?

51:41 – Outro & Next Episode Preview

52:46 – "R" Takeaways Recap

Melanotan 1 vs 2 vs PT-141 – Tanning, Arousal & What Nobody Tells You | Peptide of the Week Podcast Nov 04, 2026

Show notes

JD's Socials: https://hoo.be/jddenhamofficial

Will's Socials: https://hoo.be/williamthaas

Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

They all live in the same family but they are NOT the same. JD Denham and William T. Haas break down Melanotan 1, Melanotan 2, and PT-141, what makes each one different, the real side effects nobody warns you about, and some stories that will make you think twice about your dosing before a big meeting.

🔬 Topics Covered:

• How melanin actually works and why some people tan and others burn

• Melanotan 1: the safest of the three, FDA approved as Scenesse for sun-sensitive skin conditions

• Why MT1 does not cross into the brain and what that means for side effects

• MT1 and psoriasis: real results people are seeing stacked with BPC and TB-500

• Melanotan 2: broader spectrum, crosses into the brain, tanning plus arousal plus appetite suppression

• Why MT2 causes more flushing, more nausea, and darker freckles than MT1

• Spontaneous erections on MT2 and why Will does not sleep well on it

• PT-141 discovered as a metabolite of MT2 and why it works on the brain not the blood vessels

• Why PT-141 and Cialis together may be overkill but actually makes sense

• FDA approval of PT-141 as Vyleesi for low sexual desire in women

• Why PT-141 works for both men and women when Cialis does not

• JD's wife approved. Real world experience from both of them

• Why your hormones must be optimized or none of this works the way it should

• Dosing breakdown: MT1, MT2, and PT-141 injectable and nasal spray

• Why you do NOT take any of these before a first date or an important meeting

• When to stop because your friends are telling you that you look purple

Chapters:

00:00 – Cold Open: PT-141 Stories

01:21 – Intro

01:30 – Welcome Back & Mold Recovery Update

03:28 – Upcoming Guest Dr. Mike Farber & New Peptides

06:16 – Live VIP Workout & Bicep Measuring Contest

07:46 – Carnivore vs. Carbs & Upcoming Gear Episode

09:56 – Searching Every Peptide Mention on the Website

10:57 – Social Media Bans & Industry Camaraderie

14:24 – Today’s Compounds: The Melanotan Family

15:05 – Melanotan 1: How It Tans

23:42 – Melanotan 2: Tan, Libido & Appetite

29:49 – PT-141: Arousal, Marriage & Women

38:10 – Dosing, Mixing & Nasal Sprays

42:04 – Outro, VIP Calls & Live Workout

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