Paul Saladino MD podcast - Paul Saladino, MD

Latest Episodes:

Controversial Thoughts: The Dangers of Sunscreen! Sep 24, 2021

Show notes

Sunlight leads to a healthy microbiome! Sunlight gets such a bad rap these days, but it has SO many benefits that cannot be ignored... You haven't been told the whole story of sunlight, but I do my best to take you down the rabbit hole with me in this video. I talk about the benefits of sunlight beyond vitamin D (immune benefits and more- do we still remember that an immune system works for us?), dangers of mainstream sunscreens and what I recommend instead while you are developing a good base tan. As we head into winter, getting sunlight or UVA/UVB from sunlamps is more important than ever especially with a seasonal virus (ahem!) floating around! #theremembering

127. Is there solid science to support anthropogenic climate change? With Patrick Moore, PhD Sep 21, 2021

Show notes

Patrick Albert Moore is a Canadian industry consultant, former activist, and past president of Greenpeace. Since leaving Greenpeace in 1986, Moore has criticized the environmental movement for what he sees as scare tactics and disinformation, saying that the environmental movement "abandoned science and logic in favor of emotion and sensationalism.” According to Greenpeace, Moore is "a paid spokesman for the nuclear industry, the logging industry, and genetic engineering industry” who "exploits long-gone ties with Greenpeace to sell himself as a speaker and pro-corporate spokesperson"

Time stamps:

0:00:00 Opening thoughts

0:09:30 Podcast begins

0:10:45 The story of polar bears and how they tie into the global warming conversation

0:21:35 The first principle of science: skepticism

0:33:30 Climate and doomsday

0:42:30 Milankovitch cycles and climate change

0:54:30 Carbon dioxide isn't the issue

0:58:55 How growing plants in different levels of C02 affects their size

1:11:30 We are a tropical species

1:15:45 It's clear: temperature rises before the increase in carbon dioxide

1:28:15 The three ways heat moves from one place to another

1:32:30 C02 in the ocean

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Controversial Thoughts: Can an animal based diet help with depression/anxiety? Sep 17, 2021

Show notes

You bet it can!

The current paradigm of mental illness focuses on neurotransmitter derangements, but these are not the root of the problem in depression/anxiety etc., they are a manifestation of underlying inflammation and metabolic dysfunction. Yes. These imbalances underlie almost all chronic illness, yet western medicine sadly continues to focus on symptoms rather than addressing the root cause. What is causing the metabolic dysfunction and inflammation in many mental illnesses? Find out in this week's Controversial Thoughts video. Note: On Rumble and podcast feeds there is a bit of extra content about schmovid I cannot post here. #theremembering

126. Ivermectin, Leaky Gut in COVID, and Vaccine Mandates with Evan Brand Sep 14, 2021

Show notes

Evan Brand is a Podcast Host, Certified Functional Medicine Practitioner, and Nutritional Therapist. He is passionate about healing the chronic fatigue, obesity, and depression epidemics after solving his own IBS and depression issues. He uses at-home lab testing and customized supplement programs to find and fix the root cause of a wide range of health symptoms. His Evan Brand Podcast has over 12 million downloads and counting. He is the author of Stress Solutions, REM Rehab, and The Everything Guide to Nootropics. He offers free 15-minute functional medicine phone consultations to discuss your health symptoms and goals at his site EvanBrand.com

Time Stamps:

0:10:05 Podcast begins with Evan Brand

0:12:50 Where are we at right now with COVID?

0:15:05 Do an Altered Gut Microbiota and an Associated Leaky Gut Affect COVID-19 Severity? https://journals.asm.org/doi/full/10.1128/mBio.03022-20

0:17:00 Microbiota Modulation of the Gut-Lung Axis in COVID-19: https://www.frontiersin.org/articles/10.3389/fimmu.2021.635471/full

0:17:35 SARS-CoV-2 microbiome dysbiosis linked disorders and possible probiotics role: https://www.sciencedirect.com/science/article/pii/S0753332220311392?via%3Dihub

0:26:35 Having family members that won't listen to me

0:30:05 The history of Ivermectin and show-hosts talking bad about it

0:39:50 Why is Ivermectin getting such bad press?

0:53:40 The Media Fell for a Viral Hoax About Ivermectin Overdoses Straining Rural Hospitals: https://reason.com/2021/09/06/ivermectin-overdoses-oklahoma-hospitals-rolling-stone-hoax/

0:54:10 Misleading clinical evidence and systematic reviews on ivermectin for COVID-19: https://ebm.bmj.com/content/early/2021/05/26/bmjebm-2021-111678

1:03:25 Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088823/

1:10:05 People overwhelm themselves with information, but don't take action

1:17:05 All cows are grassfed.. until they get to the feedlot

1:22:50 What causes leaky gut?

1:24:05 Organs can help with gut, mood, and energy issues!

1:28:50 Biden: it's not about freedom anymore

1:33:20 Leaky vaccines, super-spreads, and variant acceleration

1:35:25 Natural immunity is more effective than vaccinations

1:43:05 "Reinfection" might be because of long-term inflammation, rather than getting the virus twice

1:45:45 Vaccinated and unvaccinated individuals have similar viral loads in communities with a high prevalence of the SARS-CoV-2 delta variant: https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v1

1:48:05 Who gets to decide what is true and what is false?

1:50:35 Where to find more of Evan Brand

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Controversial Thoughts: What does metabolic health really mean? Sep 13, 2021

Show notes

I've spoken a lot about the importance of metabolic health in these crazy times, but what does this really mean? Find out in this week's episode of Controversial Thoughts (also available everywhere else and on podcast feeds) Simply put it means considering body composition (not being obese, overweight or having excess visceral fat), low fasting insulin (I talk a lot about this in this video), low fasting glucose and lower levels of insulin AUC (area under the curve) after eating. It's all in this video! Please share with people you know who may benefit. This is how we truly affect lives positively long term! #theremembering

125. Red meat is a health food, with Stephan Van Vliet Sep 07, 2021

Show notes

Dr. Stephan van Vliet earned his PhD in Kinesiology and Community Health as an ESPEN Fellow from the University of Illinois at Urbana-Champaign and received post-doctoral training at the Center for Human Nutrition in the School of Medicine at Washington University in St Louis. He is currently a member of the Duke Molecular Physiology Institute within the School of Medicine at Duke University. Dr. van Vliet’s research is performed at the . In his work, Dr. van Vliet links food production systems to the nutrient density of food, and their subsequent effects on human metabolic health using high-throughput techniques such as metabolomics and proteomics. Dr. van Vliet’s studies have evaluated the effects of dietary patterns and food sources on protein and lipid metabolism, inflammation, insulin action, body composition, and intracellular signaling pathways that regulate metabolic health.

Time Stamps:

0:10:45 Podcast begins

0:11:45 The news article regarding hot dogs and shortened lifespan and why it is so misleading

0:23:45 Mortality in British vegetarians: review and preliminary results from EPIC-Oxford: https://academic.oup.com/ajcn/article/78/3/533S/4689993

0:26:15 Effects of a DASH-like diet containing lean beef on vascular health: https://www.nature.com/articles/jhh201434

0:27:15 A Mediterranean-style eating pattern with lean, unprocessed red meat has cardiometabolic benefits for adults who are overweight or obese in a randomized, crossover, controlled feeding trial: https://academic.oup.com/ajcn/article/108/1/33/5036105

0:28:45 What is it about ultraprocessed foods that make them so damaging to humans?

0:32:45 The food matrix and why it is important to consider this when doing nutritional research

0:38:45 The whole-food-matrix of meat foods

0:42:58 Elevate Markers of Oxidative Stress and Inflammation in Humans: https://academic.oup.com/jn/article/137/2/363/4664544

0:47:35 Are there specific beneficial compounds found in meat that we should highlight?

0:51:55 Red meat and colon cancer: A review of mechanistic evidence for heme in the context of risk assessment methodology: https://www.sciencedirect.com/science/article/pii/S0278691518302655?via%3Dihub

0:54:50 Health-Promoting Phytonutrients Are Higher in Grass-Fed Meat and Milk: https://www.frontiersin.org/articles/10.3389/fsufs.2020.555426/full

1:05:45 How I have shifted my thought process on phytochemicals and plant foods

1:17:30 Plant-based meat vs. real meat

1:26:15 Stephan's thoughts on organ meat

1:29:15 Current studies Stephan is working on

1:39:35 Being conscious of individuality

1:44:15 Homo sapiens are not adapted to a plant-based diet

1:49:15 What do I think about the people who don't thrive on meat-based diets?

1:54:55 Closing thoughts with Stephan

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Controversial Thoughts: What I think about cheat days! Sep 03, 2021

Show notes

I am not a fan... Check out this week's Controversial Thoughts podcast to hear why... In short, I believe that framing "cheat food," (which is usually junk food, let's be honest) as a reward sabotages long term benefits from a species appropriate human diet = an #AnimalBased diet. Getting to eat the best foods on the planet (meat, organs, fruit. honey= the foods your ancestors have celebrated most for millions of years) is an abundant privilege, not something to be framed as a scarcity. Listen to the end to hear an incredible story about our Whole Package supplement from @heartandsoilsupplements. #theremembering

124. Why you shouldn't wear sunglasses, the light episode With Andy Mant Aug 31, 2021

Show notes

Andy Mant is the Founder of BLUBlox, his passion rests in researching and educating to help empower others to lead an optimal and fulfilling life. Andy’s philosophy is to design products in line with proven academic literature to ensure BLUblox customers get only the best available technology that will actually make a difference to their health and wellbeing. Andy wants to make the science behind light management understandable to all. De-bunking science, offering digestible information that people can utilize and creating meaningful connections with our community will always be his driver.

Time Stamps:

0:08:20 Podcast begins

0:09:00 What is "junk light?"

0:16:00 Whenever we deviate from what our ancestors would have done, we run into problems

0:17:50 What is light.. exactly? And the importance of getting the right light

0:28:10 The effects of blue light on our circadian rhythm at night time

0:33:05 What are the effects on meal timing for our circadian rhythm?

0:41:30 What should you do if you have large variance in your seasons?

0:53:05 Sun tanning vs sun burning.. causes and how dietary changes effect this

1:05:35 What are some practical tips on how to construct our environment?

1:16:20 Is there a certain type of light that improves Hashimoto’s thyroiditis?

1:22:20 Is there an absolute greater amount of infrared light at sunrise and sunset?

1:25:40 What are Andy's thoughts on contact lenses?

1:30:00 Where to find more of Andy's work

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Controversial Thoughts: Do you need to count calories on an Animal Based Diet? Aug 27, 2021

Show notes

This is going to piss off the calories in/calories out zealots, but I say no... Check out this week's episode of Controversial Thoughts to hear why. I believe that our satiety mechanisms have been hijacked, and this causes us to overeat-> obesity->metabolic dysfunction. Blocking CB1 receptors with Rimonabant is incredibly helpful for weight loss and improve cardiometabolic parameters to a greater degree than weight loss would predict... Linoleic acid-> 2-AG and Anandamide (AEA) which bind to CB1, these are endogenous cannabinoids that appear to be overproduced when we eat seed oils... Is everything starting to become clear now? By eating an #AnimalBased diet (meat/organs, least toxic plant foods), you'll be avoiding seed oils and processed sugars that hijack your satiety = no real need to count calories and freedom from calorie counting prison. Don't believe me? Watch the video! #theremembering

123. Ending the debate over seed oils, with Tucker Goodrich Aug 24, 2021

Show notes

Tucker Goodrich is a technology executive in the financial industry who designs, runs, and debugs complex systems in high-risk environments. Areas of expertise include risk management, systems management, and cyber-security. After experiencing some personal health crises and realizing that the ‘solutions’ offered by medical professionals weren’t working or addressing causation he started applying the same approach in research and evaluation of data to his own health issues to determine root causes. His interests have focused on dietary and environmental drivers of chronic disease, including carbohydrate, wheat, and various classes of fats. Specifically, he’s attempting to understand and popularize understanding of the mechanisms driving the diet-derived explosion in so-called chronic diseases (or diseases of civilization). He is active on twitter (@tuckergoodrich, has a blog called Yelling Stop, is an Expert Advisor for the nutrition start-up Nutrita, and has been a guest on numerous podcasts.

Time Stamps:

0:10:16 Podcast begins

0:12:16 Tucker's blog post: https://yelling-stop.blogspot.com/2021/06/thoughts-on-of-rats-and-sidney-diet.html

0:14:16 Compounds that reduce overeating

0:17:16 Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity: https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2012.38

0:23:31 Endocannabinoid signal in the gut controls dietary fat intake: https://www.pnas.org/content/108/31/12904

0:29:56 A Neural Circuit for Gut-Induced Reward: https://www.cell.com/cell/fulltext/S0092-8674(18)31110-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867418311103%3Fshowall%3Dtrue

0:35:46 CRP is a marker of oxidized linoleic acid

0:38:32 Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials: https://pubs.rsc.org/en/content/articlelanding/2017/FO/C7FO00433H

0:43:06 Take a pill or just stop eating so many seed oils?

0:45:16 Low‐Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events: https://www.ahajournals.org/doi/10.1161/JAHA.119.016318

0:49:46 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans: https://pubmed.ncbi.nlm.nih.gov/9844997/

0:54:16 HNE - what is it and why is it important?

0:58:36 Where is linoleic acid even found?

1:02:46 The average amount of linoleic acid in the human diet

1:12:06 Why I don't eat bacon

1:14:46 Just because a study was conducted a long time ago, doesn't mean it should be ruled out

1:20:31 Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73): https://www.bmj.com/content/353/bmj.i1246

1:27:16 When low LDL can result in a higher risk of cardiovascular disease

1:28:31 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis: https://www.bmj.com/content/346/bmj.e8707

1:32:16 Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study: https://pubmed.ncbi.nlm.nih.gov/9989963/

1:40:40 The blood test you should consider getting

1:42:55 The idea of "intralipid"

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