Paul Saladino MD podcast - Paul Saladino, MD

Latest Episodes:

152. More myth debunking: TMAO, Neu5gc, Methionine/Glycine balance Feb 28, 2022

Show notes

Throughout my training and practice as a physician, I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.

00:08:33 Podcast begins

00:09:35 What is epidemiology, why is it useful, and when can we use it?

00:12:40 Vegetables + Cardiovascular disease

00:19:40 Interventional studies on vegetables

00:27:22 What is TMAO (Trimethylamine N-oxide)?

00:32:30 Choline and Carnitine

00:37:40 Mainstream literature regarding TMAO

00:41:00 TMAO in fish

00:47:28 What is Neu5gc?

00:56:03 Methionine + Glycine balance, should we worry about excess Methionine from animal foods? Should we supplement with Glycine?

01:11:18 Evolutionary consistency + how much protein should we eat?

Sponsors:

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Shirttail Creek Farm: shirttailcreekfarm.com, use code CarnivoreMD $10 off order of $100 or more

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White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order

Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd

151. How plant defense chemicals may trigger autoimmunity. Is Nicotinamide Riboside BS? Is spirulina BS? Feb 21, 2022

Show notes

00:10:57 Podcast begins

00:13:53 Paul’s framework and the hierarchy of the optimal human diet

00:19:00 Plant defense chemicals

00:19:44 Non-protein amino acids

00:34:14 Clip of Ben Patrick on The Joe Rogan Experience talking about plant defense chemicals

00:39:05 Joe Rogan clip ends

00:39:20 Hormetic properties of plant chemicals

00:43:33 Deep dive on non-protein amino acids

00:45:40 Link between plant toxins and multiple sclerosis

00:50:50 Link between non-protein amino acids and autoimmunity

1:00:00 Is algae BS?

1:04:08 Defense chemicals in seaweed

1:05:42 How to optimize cellular NAD levels

1:14:25 Why you do not need to take supplements (NR and NMN)

Sponsors:

Heart & Soil: www.heartandsoil.co

White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order

IceBarrel: www.icebarrel.com, use code PAUL for $125 off

Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd

Aura: 40% off your first order at www.aura.com/carnivore

150. Nick Bare interviews Paul on The Dangers of Seed oils Feb 14, 2022

Show notes

Nick Bare is an American YouTuber, Author, and entrepreneur. He is the CEO of Bare Performance Nutrition, founder of Embrace The Suck Training Program, and host of The Bare Performance podcast.

00:10:01 Podcast with Nick Bare begins

00:12:19 Hunting and consuming animal blood

00:19:20 Nutrition education and disease management versus biochemistry

00:20:53 Bow hunting and open fire cooking

00:23:53 The history and dangers of seed oils

00:34:53 Linoleic acids versus stearic acids, and saturated fats versus unsaturated fats

00:51:43 Where people are getting most of their linoleic acid, and thoughts on avocado/olive oil

00:57:53 Three main things to eliminate from your diet for improved health

1:02:53 Evolutionarily consistent foods and the sugar industry

1:06:38 Fruit as a primary carb source and Paul’s health journey

1:26:53 Obesity, appetite and weight loss

1:32:23 What is insulin resistance/metabolic dysfunction?

1:42:30 How do we recover from metabolic dysfunction and decrease linoleic acid intake?

1:48:53 Linoleic acid in formula versus breast milk

1:50:53 Avoiding seed oils while eating out

Where to find Nick Bare:

Podcast: The Bare Performance Podcast

Instagram: @thebareperformancepodcast

Twitter: @BarePerformPod

Website: www.bpnsupps.com

149. How to fix mold toxicity with Evan Brand Feb 07, 2022

Show notes

Evan Brand, CFMP, FNTP. Energetic, dedicated, precise, and stubbornly addicted to helping people feel better through functional medicine and creatively crafted and scientifically proven protocols that he’s used to tackle his own health struggles and thousands of clients and practitioners around the world.

00:09:24 Interview with Evan Brand begins

00:11:05 Historical evidence for mold toxicity

00:17:04 Growing and storing grain as a source of mold

00:18:20 Where can humans get exposed to mold toxins?

00:30:00 Mold toxins in dog food

00:37:00 Detoxing mycotoxins + fertility

00:40:23 Synthetic fragrances

00:44:40 Effects of mycotoxins on the endocrine system

00:46:00 Paul’s thoughts on mold contamination in meat

00:52:10 Farming in Central America and soy deforesting the rainforest

00:58:20 Linoleic acid in eggs and breastmilk

1:00:22 Alpha-gal syndrome

1:04:20 Mold detection testing: Urine testing + ERMI home testing

1:13:00 Red yeast rice + statins

00:16:30 Mold injuries

1:18:30 Symptoms of mold toxicity

1:23:45 How can people begin to heal mold injuries

1:27:30 Binders to detox from mold

1:31:50 Candida

1:14:00 Breast implants + mold colonization

1:42:48 Coffee and chocolate are BS

Listen to Paul Saladino on The Evan Brand Show:

Dr. Paul Saladino - Are Vegetables Causing Your Symptoms?

Dr. Paul Saladino MD on Carnivore Code

148. Are the Blue Zones BS or Not? Feb 01, 2022

Show notes

Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. Time Stamps:

00:08:47 Podcast begins

0:9:30 Questioning plant based diets in blue zones

0:10:35 History of the blue zones

0:14:00 Clip of Dan Buettner, inventor of blue zones concept, in an interview with Mark Hyman

0:15:00 Regions of the world left out of the five “blue zones”

0:17:25 Debunking that plant based eaters have decreased mortality. Observational research versus Epidemiology.

0:35:31 Study highlighting that Asian people who increased meat intake have lower cardiovascular disease rates in men and breast cancer rates in women

0:40:46 Study highlighting correlation between red meat and male height

0:43:41 Examining blue zones in detail

1:06:50 Information about the 2022 Animal Based Gathering. (animalbasedgathering.com)

1:07:30 Study highlighting the unexpected effects of red meat in terms of longevity

1:15:00 Creating our own micro blue zones and the negative side effects of plant molecules

Sponsors:

Heart & Soil: www.heartandsoil.co

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

BluBlox: Blublox.com, use code CarnivoreMD for 15% your order

Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt

Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

147. Ask Me Anything (AMA): Fructose, Fish Oil, Maple Syrup, and more… Jan 24, 2022

Show notes

0:09:22:18 Podcast begins

0:11:31 Clip of Ben Patrick on Joe Rogan Podcast discussing animal based eating.

0:21:31 Paul’s commentary on Ben Patrick and Joe Rogan’s conversation.

0:22:01 Fructose fear mongering and thoughts on fruit in an animal based diet.

0:34:45 Connection between Nitric Oxide and insulin resistance.

0:40:23 Thoughts on maple syrup.

0:42:42 Why Paul originally introduced fruit and carbs into his diet.

0:45:35 Hierarchy of foods for humans that are hunter gatherers.

0:47:40 Commentary on Joe Rogan’s diet and thoughts on a chronic accumulation of plant defense chemicals from plant foods.

0:51:25 Reactive hypoglycemia and caffeine.

0:53:40 Omega 3 Fatty Acids: How valuable are they? Should we supplement with fish oil?

0:58:22 Fish oil is bullshit.

1:03:01 Paul shares his Essential and Metabolic Fatty Acid lab results from August 2021.

1:09:53 Nutrient adequacy on an animal based diet.

1:20:30 The Rotterdam study

1:27:00 Xenohormesis and the net negative of plant compounds.

1:30:15 Resveratrol versus fasting, heat and cold and mTOR.

Sponsors:

Heart & Soil: www.heartandsoil.co

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

BluBlox: Blublox.com, use code CarnivoreMD for 15% your order

Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt

Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

Listen to Ben Patrick on Fundamental Health: How to make yourself a world-class athlete (or be free from knee pain forever!) with Knees Over Toes Guy, Ben Patrick

146. Does Red Meat Accelerate Aging, with David Sinclair PhD - UPDATE and REPOST Jan 17, 2022

Show notes

David Andrew Sinclair, PhD is an Australian biologist and professor of genetics. He is also a co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, and is known for his research on aging with a focus on epigenetics.

Time Stamps:

0:35:27 Podcast begins with David Sinclair

0:36:25 Is when we eat more important than what we eat?

0:38:45 What is the connection between time restrictive eating and longevity?

0:43:54 What causes us to age?

0:45:46 Epigenetic change.

0:52:03 What causes DNA breaks?

0:55:28 What plant foods create DNA breaks?

0:57:13 PARP enzymes

1:00:46 Where does NAD come from? How do we make it? What enzymes use it?

1:04:50 NAD recycling pathway.

1:12:13 Sirtuins.

1:24:14 What are the other longevity genes? (AMP kinase and mTOR) How are they connected to sirtuins?

1:31:50 Does being in a ketogenic state increase NAD?

1:40:30 Xenohormesis and plant molecules.

1:45:50 Resveratrol trials.

1:51:55 mTOR.

1:57:25 David’s thoughts on animal protein.

2:04:03 Meat consumption in relation to the environment and regenerative agriculture.

2:11:28 Where to find David Sinclair.

David’s info:

https://genetics.med.harvard.edu/sinc...

https://lifespanbook.com/

Instagram: @davidsinclairphd

Twitter: @davidasinclair

Sponsors:

Heart & Soil: www.heartandsoil.co

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

The Cold Plunge: TheColdPlunge.com, use code CarnivoreMD for $111 off your cold plunge

Eight Sleep: https://www.eightsleep.com/carnivoremd use code “CARNIVOREMD” to save $150

Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt

145. Heidi Montag (The Hills) Interviews Paul about Animal Based 30 Jan 11, 2022

Show notes

Heidi Blair Pratt is an American television personality and singer. In 2006, she rose to prominence as one of the original cast members on The Hills, a former MTV reality television series. In 2007, Montag began working on her debut album, Superficial, which was released in January 2010. Montag and her husband Spencer Pratt, who was also featured on The Hills, have received much negative attention in the media, notably for their participation on the second season of I'm a Celebrity... Get Me out of Here!. In 2010, Montag gained further attention after having ten plastic surgery procedures done in a single day.

Time Stamps:

0:09:50 Podcast begins with Heidi Montag

0:12:20 Do I wear sunscreen in Costa Rica? What do I recommend for skin protection?

0:25:20 What about soaps and skin care products in general? Do I use toothpaste?

0:29:00 What do I recommend for makeup products for women?

0:34:20 How to make healthy eating a living for chldren easier and more socially accepted?

0:41:05 How bad is wine and adult indulgences? Can you get all your nutrients from meat, organs, and fruit?

0:49:50 Plants and defense mechanisms

0:58:05 How much fruit should someone eat per day?

1:02:20 Are there any supplements I recommend?

1:08:50 Is there a risk to eating raw foods? Is there a risk to taking Heart & Soil supplements?

1:10:05 What about chicken and pigs?

1:14:50 What about water? Does shower water matter?

Sponsors:

Heart & Soil: www.heartandsoil.co

Animal-Based Gathering: https://www.animalbasedgathering.com/

Force of Nature Regenerative meats: Forceofnature.com use code CarnivoreMD22 for $15 off your entire order

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

144. 2022 Kick Off Ask Me Anything (AMA): Cholesterol, Skin Care, Liver, and More Jan 04, 2022

Show notes

Time stamps:

0:03:15 Podcast begins, my framework for everyone, should you listen to me?

0:09:00 What is the most ancestrally-consistent, nutrient-dense, and least offending diet for humans?

0:15:55 First question: What to reply to friends who say "I am killing myself"

0:20:00 Second question: What role does animal-based eating have on coronary artery disease?

0:24:15 Third question: What skin care products would you recommend for the face and eczema?

0:28:55 Doesn't the sun age us?

0:29:30 Fourth question: How can a child improve their gut microbiome?

0:31:15 Fifth question: What could be causing my muscle twitches?

0:33:30 Sixth question: Is the liver a filter for toxins? What are the benefits of eating liver?

Sponsors:

Heart & Soil: www.heartandsoil.co

Force of Nature Regenerative meats: Forceofnature.com

BluBlox: Blublox.com, use code CarnivoreMD for 15% your order

Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

143. The best of the Fundamental Health podcast, 2021 year in review Dec 28, 2021

Show notes

Sponsors:

Heart & Soil: www.heartandsoil.co

White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order

BluBlox: Blublox.com, use code CarnivoreMD for 15% your order

Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt

Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

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