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Stop Guessing: Your Genes Reveal the Best Diet & Workout
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Dr. Sam Shay - Genetics Testing
FitGenesUSA.com
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In this episode of Over 40 Fitness Hacks, I sit down with returning guest Dr. Sam Shay, Functional Medicine Certified Practitioner and Western Hemisphere Director of FitGenes USA, to explore the latest advancements in genetic testing for health, fitness, and longevity. Building on our previous conversation about the "10 Pillars of Health," Dr. Shay explains why genetic testing provides the blueprint for making smarter decisions about nutrition, exercise, recovery, and biohacking.
Dr. Shay discusses how most genetic reports overwhelm people with hundreds of confusing data points, while FitGenes focuses on prioritizing the most actionable genes related to inflammation, mitochondrial function, detoxification, vitamin D metabolism, methylation, cardiovascular health, and fat metabolism. Instead of generating information overload, the goal is to provide clear lifestyle recommendations that have the greatest impact.
We also dive into one of the most fascinating aspects of the conversation: using genetics to determine your ideal diet. Dr. Shay explains how copy number analysis of the AMY1 gene can reveal whether your body is naturally better suited for a ketogenic, paleo, Mediterranean, or higher-carbohydrate diet. He shares how discovering his own genetic carb tolerance dramatically improved his energy, digestion, mood, and overall health after years of following the wrong eating plan.
Beyond nutrition, we discuss how genetics can guide exercise programming by identifying whether you're genetically predisposed for endurance or power training, your risk for exercise-induced inflammation, collagen strength, injury susceptibility, and recovery needs. Dr. Shay emphasizes that many people unknowingly overtrain simply because they're following popular fitness trends instead of training according to their genetic blueprint.
Dr. Shay also gives viewers an inside look at the redesigned FitGenes reports, showing how they summarize key recommendations on a single page—including ideal diet, top nutrient priorities, exercise type, recovery strategies, and food sensitivities—making the information practical for both practitioners and everyday users.
Throughout our discussion, we talk about why genetics should be one of the first investments for anyone interested in biohacking or longevity. Unlike other health metrics that change over time, your DNA never changes, making genetic testing a lifelong roadmap that can help guide future lab work, supplementation, nutrition, and training decisions.
If you're interested in personalized health optimization and want to stop guessing which diets, supplements, or exercise programs are right for you, this episode provides an excellent introduction to how genetic testing can help create a personalized blueprint for lifelong health and performance.
If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:
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Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.
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