On The Pen GLP-1 News

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**On The Pen GLP-1 News**

On The Pen is the leading GLP-1 news podcast and platform covering obesity medicine, FDA actions, drug shortages, access policy, and the business of NuSH therapies. The podcast is in the top 0.5% of all podcasts globally, and On The Pen is a top Substack best-seller.

Latest Episodes:

On The Pen: The Weekly Dose 8.6.24 Aug 06, 2024

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Fortune interview:

https://fortune.com/2024/08/02/eli-lilly-mounjaro-zepbound-weight-loss-ceo-alzheimers-drug/

Tirzepatide shortages (viral tiktok video with 199,000+ views):

Tirzepatide heart trial (viral tiktok video with 90,000+ views)

https://www.onthepen.com/post/zepbound-s-cardiovascular-benefits-and-the-future-of-medicare-coverage

semaglutide pre-diabetes trial:

https://www.sciencedirect.com/science/article/abs/pii/S2213858724001827

Weight Watchers:

https://www.bloomberg.com/news/articles/2024-08-01/weightwatchers-to-cut-jobs-spending-as-business-declines?srnd=homepage-asia&embedded-checkout=true

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

On The Pen: The Weekly Dose 7.30.24 Jul 30, 2024

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Book Email Alerts: https://www.onthepen.com/glp1-book
Altimmune

https://ir.altimmune.com/news-releases/news-release-details/altimmune-announces-publication-clinical-study-pemvidutide

Novo Nordisk Expansion:

https://www.fiercepharma.com/pharma/amid-wegovy-and-ozempic-boom-novo-eyes-new-facility-200-acre-land-buy-denmark

Novo Nordisk Fire:

https://www.thelocal.dk/20240724/danish-emergency-services-put-out-minor-fire-at-novo-nordisk

Novo Nordisk EU Wegovy:

EU agreed to label expansion for Wegovy to reduce heart attack risks
https://www.morningstar.com/news/dow-jones/2024072511614/novo-nordisks-wegovy-gets-eu-regulator-endorsement-to-reduce-heart-risks-update

Roche:

https://www.reuters.com/business/healthcare-pharmaceuticals/roche-fast-track-weight-loss-pill-compete-with-rivals-ft-reports-2024-07-29/
https://www.onthepen.com/post/more-threats-to-lilly-s-tirzepatide-printing-pressWeight Watchers:

Weight Watchers Resignation:

(Madison Muller) https://www.bloomberg.com/news/articles/2024-07-25/weightwatchers-chief-medical-officer-leaves-after-less-than-year

FDA and compounding:

https://www.politico.com/newsletters/prescription-pulse/2024/07/26/compounding-the-glp-1-craze-00171314https://www.onthepen.com/post/compound-tirzepatide-choosing-the-right-sourceFDA and compounding (tiktok video)

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On The Pen: The Weekly Dose 7.23.24 Jul 22, 2024

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On The GLP-1 Pen Book Alerts:
https://onthepen.com/emails
Gan & Lee (China)
https://www.prnewswire.com/news-releases/gan--lee-pharmaceuticals-bi-weekly-twice-a-month-glp-1-receptor-agonist-gzr18-injection-achieved-17-29-weight-loss-at-30-weeks-in-a-phase-iib-clinical-trial-302202575.html
Mazdutide (China):
https://www.fiercebiotech.com/biotech/innovent-bags-another-phase-3-win-next-gen-lilly-glp-1-drug
China:
https://www.reuters.com/business/healthcare-pharmaceuticals/eli-lillys-weight-loss-drug-tirzepatide-gets-approval-china-2024-07-19/
Retatrutide (tiktok video):
https://www.nature.com/articles/s41421-024-00700-0
GLP-1 Temperature Monitor:
https://www.varcode.com
Eli Lilly:
https://www.bioprocessonline.com/doc/how-eli-lilly-s-making-peptides-faster-and-more-reliably-0001

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On The Pen: The Weekly Dose 7.16.24 Jul 15, 2024

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PBM reform in Illinois (tiktok video)

https://x.com/ManOnMounjaro/status/1812833885375332394

FTC on PBM

FDA and social media (tiktok video)

https://news.bloomberglaw.com/health-law-and-business/drug-device-online-misinformation-gets-fda-look-after-10-years

Patient weight-loss expectations

https://www.endocrinepractice.org/article/S1530-891X(24)00564-0/abstract

Wegovy commercial:

https://www.business2community.com/business-news/ozempic-wegovy-maker-novo-nordisk-spends-record-42-m-to-promote-the-drugs-on-tv-is-it-working-02813548

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Amylin and the future of obesity medicine with Dr. Beverly Tchang Jul 13, 2024

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Dave chats with world renowned obesity expert who consults for the likes of Novo Nordisk!
Beverly Tchang, MD is a triple board-certified physician with a focus on obesity medicine. Since 2018, she has been treating patients and training professionals in endocrinology and obesity. Her nationally recognized expertise has led her to extend her knowledge and experience as an advisor to companies, entrepreneurs, and investors who want to learn about modern weight management.
BeverlyTchangMD.com
X: @bevTchangMD

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On The Pen: The Weekly Dose 7.9.24 Jul 08, 2024

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Ozempic reduces cancer risk:

https://www.bloomberg.com/news/articles/2024-07-05/ozempic-may-lower-risk-of-obesity-related-cancers-study-finds

Semaglutide correlated with blindness (tiktok video):

https://www.statnews.com/2024/07/03/ozempic-wegovy-naion-vision-loss-study

15-years as type-2 diabetic results in a 78% chance of have some degree of retinal eye damage

https://www.webmd.com/diabetes/closer-look-diabetic-retinopathy

Update to Mounjaro/ZepBound FDA shortage on 7/2/2024 (tiktok video)
#releasethevials

https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Tirzepatide%20Injection&st=c

Mounjaro KwikPen coming to Australia

News provided by Mimi from Australia (Mimi featured in Live #61 -- part of Retatrutide trials

GIP scientific study:

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16478

semaglutide vs. tirzepatide

https://www.nbcnews.com/health/health-news/zepbound-outperforms-ozempic-wegovy-head-head-weight-loss-study-rcna160630

Keto diet:

https://www.biorxiv.org/content/10.1101/2024.06.14.599117v1

High-price of GLP-1 medications:

https://www.usatoday.com/story/opinion/2024/07/02/biden-sanders-prescription-drug-cost-ozempic-wegovy/74232827007/?tbref=hp

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On The Pen: The Weekly Dose 7.2.24 Jul 02, 2024

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Get OTP Emails: https://www.onthepen.com/emails
Eli Lilly

Eli Lilly sent cease and desist letters to providers of research grade GLP-1s
Exclusive news from onthepen.com that has not been covered by any other source
https://www.onthepen.com/post/generic-versions-of-zepbound-how-recent-news-affects-their-future

Him & Hers:

Him & Hers giving GLP medications without consulting with a doctor
https://hntrbrk.com/hims/

Price for generic liraglutide/Victoza (multiple tiktok videos):

Note: podcast last week announced generic liraglutide from Tera Pharma
Prices as low as $225 for two pens
https://www.goodrx.com/liraglutide?form=carton&dosage=2-pens-of-18mg-3ml&quantity=1&label_override=liraglutide

TROA

Scaled-back TROA bill is passed out of the US House Ways and Means Committee
This version would limit coverage to people who had been taking a weight loss drug for a year prior to enrolling in Medicare
https://www.nbcnews.com/health/health-news/house-committee-passes-bill-allow-medicare-cover-weight-loss-drugs-rcna159248

BI 3034701 (tiktok video):

Boehringer Ingelheim and Gubra start phase 1 trial of BI 3034701 which is retatrutide competitor (GLP-1/GIP/glucagon)
https://www.boehringer-ingelheim.com/science-innovation/human-health-innovation/phase-1-start-novel-triple-agonist-obesity-treatment

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On The Pen: The Weekly Dose 6.25.24 Jun 25, 2024

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Novo Nordisk expansion in the US:
https://www.novonordisk.com/news-and-media/news-and-ir-materials/news-details.html?id=168528

Generic liraglutide
https://www.onthepen.com/post/teva-launches-first-ever-generic-glp-1-a-game-changer-for-diabetes-and-weight-management

New Wegovy Coupon:
https://www.wegovy.com/coverage-and-savings/save-on-wegovy.html

New Mounjaro Card (tiktok video)
https://mounjaro.lilly.com/savings-resources

Tirzepatide (tiktok video):
https://www.reuters.com/business/healthcare-pharmaceuticals/weight-loss-drug-zepbound-resolves-sleep-apnea-up-52-patients-lilly-says-2024-06-21/

Petrelintide
https://www.onthepen.com/post/introducing-petrelintide-discover-the-promise-of-amalyn-agonist-medications-for-weight-loss

Gut bacteria:

Interesting research that shows that type-2 diabetics have more microbiome in their gut that suppresses incretin hormones like GLP-1. This is more evidence that #glp1 medications fix what is biologically broken
https://www.onthepen.com/post/glp-1-slow-responders-gut-bacteria-may-hold-the-key

DACRA:
https://ir.vikingtherapeutics.com/2024-06-24-Viking-Therapeutics-Presents-Preclinical-Data-on-Novel-Dual-Amylin-and-Calcitonin-Receptor-Agonists-at-84th-Scientific-Sessions-of-the-American-Diabetes-Association

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On The Pen: The Weekly Dose 6.18.24 Jun 18, 2024

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PBM Reform Form Letter:

Link to the Letter: https://www.onthepen.com/post/pbm-reform-form-letter-for-elected-representatives

Express scripts (tiktok video on PBM reform):

Link to my video: https://www.youtube.com/watch?v=l0g6RwViOxc

Michigan (tiktok video)

Link (Madison Muller): https://www.bloomberg.com/news/articles/2024-06-12/michigan-s-largest-insurer-to-drop-weight-loss-drug-coverage

Accessibility

Link: https://www.benefitspro.com/2024/06/13/8-ways-to-use-behavioral-science-to-address-obesity/?slreturn=20240614174121

Vivani (tiktok)

Link: https://www.businesswire.com/news/home/20240613953589/en/Vivani-Medical-Announces-FDA-Clears-Investigational-New-Drug-Application-and-Lifts-Clinical-Hold-for-NPM-119-a-Miniature-Long-Term-Subdermal-GLP-1-Drug-Implant

Diet on GLP-1:

Online GLP-1s:

Link: https://www.npr.org/sections/sho

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Zepbound And Liver Disease Jun 12, 2024

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Eli Lilly's phase 2 SYNERGY-NASH study shows tirzepatide effectively resolves MASH and improves fibrosis, offering hope for millions. Read more here: https://www.onthepen.com/post/tirzepatide-shows-promise-in-treating-mash-key-findings-from-the-synergy-nash-study

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