Mitolife Radio

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Why I Left the Root Cause Protocol and Thoughts on Iron Deficiency Dec 05, 2025

Show notes

I have been hearing about iron overload since 2012 from various natural health educators. In 2019 the seeds that were sprouted in my mind fully developed as I completely embraced the idea that everybody has iron overload and nobody is iron deficient. I went full steam ahead with that idea for the next several years, making it a core part of my health message.

I practiced what I preached and donated blood twice. The first time I felt superhuman - very mentally clear and energetic. The second time I donated blood it gave me extreme fatigue, brain fog, and muscular weakness that took me a long time to recover from.

This show is not meant to disparage or restart a fight, but to make it crystal clear to those that don't follow me on social media my stance on iron. Many women and even some men (former vegans/vegetarians) are suffering from the symptoms of iron deficiency such as hair loss and fatigue.

Most people are unaware that ascorbic acid suppresses hepcidin at 1000mg dose which increases non-heme iron absorption. That is important to know if you are trying to build your savings account (serum ferritin) with supplementing iron bisglycinate. I also talk about how L-lysine amino acid is underrated for restoring your iron status, the role of vitamin E, and how the widespread heavy metal toxicity makes iron deficiency worse.

I talk about why serum ferritin is in fact an accurate representation of tissue iron stores according to top iron researchers, why zinc is crucial for proper iron metabolism, how you can tell if you are deficient in iron without any bloodwork, the best iron supplements i've found, the permanent brain damage to the baby that occurs if a pregnant women is iron deficient, and I ask why the Root Cause Protocol people never talk about iron deficiency without anemia and the three different stages.

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by George Henner: https://georgehenner.bandcamp.com

Kidney Failure: It is Damaged Mitochondria Nov 29, 2025

Show notes

I receive a lot of health questions about how to remedy various debilitating conditions. One of the more concerning questions I receive frequently is regarding kidney failure. Why is there an epidemic of people with failing kidney function? It comes down to mitochondria dysfunction.

Instead of focusing in one one study like most health educators do, my goal with these short shows is to paint broad strokes and cover the entire subject from a birds eye view all the way down to the mitochondrial level. Most importantly, as I cover various health conditions in future episodes, I will focus very heavily on the solutions, citing research and mechanisms to back up each of the proposed supplements or protocols.

In the case of the kidneys, it comes down to one protein: mitochondrial transcription factor A, or TFAM. When that critical protein inside mitochondria in your kidneys becomes deficient, energy production falls and tissue function decreases, hence, kidney failure. It always comes back to mitochondria.

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by George Henner: https://georgehenner.bandcamp.com

Two studies I referenced:

Mitochondrial Energetics in the Kidneys

https://pmc.ncbi.nlm.nih.gov/articles/PMC5965678/#:~:text=The%20kidney%20is%20one%20of,pressure%20in%20the%20glomeruli5.

Loss of Mitochondrial Transcription Factor A (TFAM) in Tubule Cells Causes Renal Failure

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3346980

Q&A: What the Anti PUFA Crowd Gets Wrong and Melatonin Dosing for Kids Nov 21, 2025

Show notes

In this months Q&A episode I answer listener questions including: What are my thoughts on B vitamins? Should we supplement them or get them from food? What is one thing the anti PUFA crowd gets wrong? What are my thoughts on testing omega 3:6 ratio from a dried blood spot sample? What do I think about Dr Matthew Walker on Diary of a CEO Podcast saying "don't supplement large doses of melatonin"? What is a good dose of melatonin for kids? Have I ever taken melatonin to lower anxiety? What do I think about red light and PEMF mats? What is my parasite strategy? What belief or mindset shift created the biggest change in my health?

I share why I think vitamin B3 as niacinamide/nicotinamide is one of the most important ones to take, how B3 protects against several different types of cancers, why cigars don't protect from pathogens in oysters, the immense stress lowering effect I felt when I stopped demonizing ascorbic acid, zinc, iron, and vitamin D supplements, and why I think the should observe the diets of deer and elk with the PUFA conversation instead of getting lost in analyzing endless research studies.

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

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Some of the studies cited in the show:

NIacinamide skin cancer study

https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/

Niacinamide non hodgkin lymphoma study

https://pubmed.ncbi.nlm.nih.gov/37467318/

PUFAs as Anti-Freeze article:

https://www.anbg.gov.au/cryptogams/underworld/panel-13/index.html

Music by George Henner: https://georgehenner.bandcamp.com

My Heavy Metal Detox Strategy Nov 14, 2025

Show notes

There are many different philosophies in the natural health world about where people should start with their health. Some focus on increasing carbs, some focus on increasing protein, some focus on both. I've heard people in the Ray Peat community say that heavy metal detox is a fad and its not important.

For the first half of the show I break down why I think its a great place to start, the biochemistry of exactly how heavy metals harm our cells, how car exhaust contributes to their accumulation, and my thoughts on tracking using HTMA and the Oligoscan.

In the second half I talk about solutions, starting with the most affordable to the least affordable. I reference a study looking at the difference in heavy metal excretion of 5 metals using sweating in a sauna or sweating during exercise and which one they found to be more effective. I talk about why I supplement magnesium, zinc, shilajit, and high dose melatonin everyday, and how fiber and high dose zeolite powder can also help.

This is by no means a comprehensive show that includes every nuance of heavy metal toxicity. The focus was to make it interesting, digestible, and share actionable steps no matter where you are financially.

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by George Henner: https://georgehenner.bandcamp.com

Structured Water and Filtration, Finally Combined Nov 07, 2025

Show notes

Finally, an elegant water filter that actually filters out all contaminants and structures the water at the same time. The Mitolife EZ Flow structured water filter cleans the water in the first four stages, using a combination of a 5 micron sediment filter, KDF55, reverse osmosis, cation resin, and catalytic carbon.

Inbetween those effective filtration processes the water is flowing through stages that make the water "ordered" or "coherant". This includes powerful neodynium magnets and 850 nanometer light on a hydrophilic surface, replicating the research of Dr Gerald Pollack and others on forming structured water in the laboratory. Of all the wavelengths of light, infrared light forms it the best.

It also goes through elite type 1 unpolished shungite from Russia. This has never been done before in any water filter in the world. Containing 95% + carbon, it is a source of "buckminsterfullerine", or C60, an expensive supplement that people take for anti-aging and detoxification purposes. The remaining content of shungite is similar to shilajit with regards to its mineral content, so it is a natural remineralizer, even if just very small trace amounts. People in Russia have been using shungite to purify collected water in the wild since at least the 1700s, but likely much longer. There are also published studies on shungite's EMF protective effects, and we know that man-made EMFs have the ability to make water less coherant. This is my favorite part about this water filter.

Wait, there's more. Then it goes through 100 to 200 vortexes right before it travels up to your spigot. Inbetween draws from the storage tank there is a large build-up of exclusion zone (EZ) water in the infrared light chamber. This is the most exciting product that I've ever released and I am excited for you to experience this water that has a gel-like thicker consistency.

Order the filter: https://www.mitolife.co/products/ez-flow-structured-water-filter

My website: www.matt-blackburn.com

Music by George Henner: https://georgehenner.bandcamp.com

Why I Megadose Melatonin Every Night Oct 31, 2025

Show notes

Dubbed a sleep hormone, melatonin has been branded as a bandaid and short term fix to help you fall asleep. The health influencers told you that its dangerous because it will decrease your body's production if you supplement it. A popular quantum health neurosurgeon once made the ridiculous claim that it changes the shape of your eyeball if you take a melatonin pill, with zero clinical study to back up his claim.

It turns out that melatonin is anti-tumor, anti-viral, anti-anxiety, anti-inflammatory, and protects your mitochondria from a myraid of assaults, one of which being electromagnetic field (EMF) exposure.

In this episode I address the main three myths that are spread about melatonin and explain why they are wrong. I talk about how most of your melatonin is not made in your pineal gland, how simple melatonin powder is the way to go over rectal or other delivery methods, and I reference a few dozen fascinating studies that talk about the various benefits of supplementing melatonin.

Show resources:

https://onlinelibrary.wiley.com/doi/10.1111/jpi.70094

https://pmc.ncbi.nlm.nih.gov/articles/PMC7211589/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6017232/

https://www.spandidos-publications.com/10.3892/ijmm.2024.5352

https://pubmed.ncbi.nlm.nih.gov/38214233/

https://pubmed.ncbi.nlm.nih.gov/30192001/

https://api.doris-loh.com/catalog/April_2023_Melatonin_Dosing_Schedule.pdf

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by George Henner: https://georgehenner.bandcamp.com

Why I Love My Electric Vehicles Off Grid and Mitigating The EMF Oct 17, 2025

Show notes

I have noticed the hatred towards electric vehicles growing the past five years in the natural health world. The topic has become political and there is a clinging to tradition, similar to people that didn't want to abandon the horse and buggy for the automobile, but that will pass with time. I have been saying for years: Why not see the utility and different use cases in both electric cars and gas and diesel cars?

In this long time coming episode I talk about why I love owning electric vehicles being 100% off grid, the expensive lessons i've learned over the years to do it easily, how electric cars can provide ultimate freedom with solar panels, the only two car brands I found that work easily off grid, the details of my off grid setup, and I share one source of information that breaks apart every common myth you've ever heard about EVs.

The biggest focus of the show is on the electromagnetic field exposure that you get riding in them. I talk about radiofrequency (RF), magnetic, and electric fields and specific supplements that fully protect your cells and mitochondria from harmful effects, namely lipid peroxidation. Human health is about adaptation, not putting yourself in a bubble. We can enjoy modern technological advancements without sacrificing our health or sovereignty.

My website: www.matt-blackburn.com

My supplements: www.mitolife.co

Study I referenced: https://pmc.ncbi.nlm.nih.gov/articles/PMC9608227/

Ben Sullins EV myths: https://www.youtube.com/@BenSullinsOfficial/featured

Lipofuscin: Cellular Kryptonite That Nobody Talks About Sep 26, 2025

Show notes

There is a lot of talk about autophagy, or cellular recycling, and apoptosis, programmed cell death, in relationship to circadian rhythm entrainment, ketogenic diets, and intermittent fasting. What I never hear is people talking about lipofuscin, the intracellular kryptonite and shuts down both of those processes by gumming up the lysosomes of our cells. When the garbage recycling center of our cells gets up to 75% full of this nearly non-degradable material, our mitochondria, cell, and tissue function fails.

In this episode I focus on the exact biochemical mechanisms of how lipofuscin causes harm, not just being an inert substance but one that generates inflammation itself, keeping our requirements for antioxidants chronically elevated. I break down its relationship to redox active metals and the fascinating light connection with photo-induced free radical generation.

I talk about why I believe vitamin E to be the best solution. I explain how oxidized vitamin A plays a role in lipofuscin formation, but why we shouldn't join the "vitamin A is a toxin" camp and instead prioritize keeping our vitamin E status up which protects A from oxidation. While there aren't human studies on red light therapy or photobiomodulation for lipofuscin, I share why I bathe myself in front of a red light panel everyday and how I think it works for mitigating lipofuscin. I did not have time for listener questions for this episode but i'll break down the nuances of each part of my CLF protocol (calcification, lipofuscin, and fibrosis) in future episodes.

My website: www.matt-blackburn.com

The CLF Protocol: https://www.matt-blackburn.com/blogs/news/the-clf-protocol-lipofuscin

Mitolife products: www.mitolife.co

Music by Nicholas Jimenez: https://spoti.fi/4cte2nD

Glyphosate: The Pesticide Causing Chronic Disease with Dr Stephanie Seneff Sep 19, 2025

Show notes

In this episode Dr Stephanie Seneff PhD explains how autism, Parkinson's, ADHD, brain fog, anxiety, depression, and hormone disruption are related to the pesticide glyphosate. She talks about the mechanisms of how it affects bacteria and disrupts our ecosystem. I ask her if donating blood lowers glyphosate, potential supplements that can help remove it, and her thoughts on alcohol, cannabis and tobacco as they relate to glyphosate. She talks about why she loves sulfur rich foods, why she isn't a fan of Ozempic and statin drugs, how manganese gets targeted by glyphosate, her thoughts on gluten intolerance, and more.

Stephanie's website: https://stephanieseneff.net

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by Nicholas Jimenez: https://spoti.fi/4cte2nD

Using the Sugar Diet for Weight Loss with Gwenyth Burmingham Sep 12, 2025

Show notes

There is always a new diet circulating and they always get a lot of engagement. What makes the sugar diet unique is that it challenges the mainstream idea that sugar consumption causes weight gain. What the mainstream doesn't tell you is that fatty acids and glucose compete for absorption, so consuming lower fats while consuming a lot of carbohydrates with adequate protein will actually increase the metabolic rate and turn you into a "fat burner" like the keto people talk about.

Gwenyth Burmingham joins us to talk about how she is using this as a short-term tool to support her weight loss goals. She talks about the importance of collagen and gelatin, why she thinks high protein consumption is overhyped, what she consumes everyday on the sugar diet, why she believes everyone has some estrogen dominance, why she likes topical progesterone, and more.

Her website: https://growinggwenyth.com

Her social media: https://www.instagram.com/growing.gwenyth/

My website: www.matt-blackburn.com

Mitolife products: www.mitolife.co

Music by Nicholas Jimenez: https://spoti.fi/4cte2nD

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