Journal of Clinical Oncology (JCO) Podcast

Latest Episodes:

Better Outcome of Chemo-Irradiation of Head and Neck Cancer in High-Patient-Volume Institutions Dec 08, 2014

Show notes

In a randomized RTOG study of chemotherapy concurrent with accelerated vs standard fractionated radiotherapy for head and neck cancer, it was found that patients treated in institutions who accrued a large number of patients had better outcomes compared with those treated at low-volume institutions, highlighting the importance of referring patients with advanced cancer to high-volume centers.

Is There a Future for Cyclooxygenase-2 Inhibition in Non-Small Cell Lung Cancer? Dec 01, 2014

Show notes

This podcast reviews the available data from clinical trials using cyclooxygenase-2 inhibition with chemotherapy in non-small cell lung cancer and provides a perspective on patient selection and future directions.

The Treatment of Insomnia in Cancer Patients Dec 01, 2014

Show notes

This four-arm randomized controlled trial of cognitive behavioral therapy for insomnia in cancer patients confirmed its effectiveness but did not demonstrate benefit from the addition of a daytime wakefulness-promoting agent.

The Biopsy Study: How the Use of Multiple Colposcopic-Directed Biopsies Improves Detection of Cervical Precancers Nov 25, 2014

Show notes

This podcast is a review of the submitted article by Dr. Wentzensen and colleagues regarding multiple cervical biopsies at the time of colposcopy and the implications for the management of cervical dysplasia.

Intensified Frontline Chemoimmunotherapy with R-ACVBP May Improve Outcomes for Younger Patients with Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma Nov 25, 2014

Show notes

A secondary analysis of a multicenter randomized trial suggests that the R-ACVBP regimen may improve outcomes in younger patients with the non-germinal center B-cell subtype of diffuse large B-cell lymphoma.

A Positive Study of DTC-Guided Secondary Adjuvant Treatment in Early Breast Cancer: Ready for Prime Time? Nov 25, 2014

Show notes

Modifying therapy based upon positive DTCs in breast cancer.

A Second Course of Radiation Therapy for Painful Osseous Metastases Improves Patient Function and Quality of Life Nov 25, 2014

Show notes

NCIC SC.20 demonstrates that a second course of radiation for painful osseous metastases significantly improves patients quality of life and function.

Adjuvant Trastuzumab Passes the Test of Time Nov 25, 2014

Show notes

Long-term follow up from the landmark, NCI-sponsored adjuvant trastuzumab trials confirms the clinical benefits and clinical safety of this important therapy.

Prognostic Value of BRAF V600 E Mutation in Papillary Thyroid Cancer Nov 25, 2014

Show notes

This podcast provides a commentary on the association of braf mutation and thyroid cancer showing an increase risk of recurrence in patients with thyroid cancer that harbor this mutation.

Biochemotherapy: As Time Goes By? Nov 25, 2014

Show notes

In this podcast, the results of the S0008 adjuvant intergroup trial are discussed and placed in the context of current advances in melanoma treatment.