Journal of Clinical Oncology (JCO) Podcast

Latest Episodes:

Deciphering the Heterogeneity Within EGFR-mutant Lung Cancer Apr 20, 2015

Show notes

A meta-analysis of 7 randomized trials comparing EGFR kinase inhibitors to chemotherapy for advanced EGFR-mutant lung cancer has shown that some populations gain greater benefit from targeted therapy – namely never-smokers, woman, and tumor harboring exon 19 deletions.

Precision Immunology: The Promise of Tumor Immunotherapy for the Treatment of Cancer Apr 15, 2015

Show notes

This podcast discusses a novel immunotherapy approach using an allogeneic whole tumor cell vaccine to prime, and a recombinant antigen-encoded bacterial vector to boost, immune responses against pancreatic cancer and explains why this approach may be beneficial in the treatment of advanced pancreatic cancer.

The Importance of Discussing Genetics with Every Breast Cancer Patient Apr 14, 2015

Show notes

In summary, healthcare providers caring for breast cancer patients hopefully recognize the need for consideration of genetic testing in appropriate individuals, and communicate that need to the patient. A discussion about why genetic testing is not appropriate may be as beneficial as one about why it is, and oncology providers should consider briefly discussing genetics with all patients, even if the subject is provider-initiated.

Hematopoietic Stem Cell Transplant for Children With Acute Lymphoblastic Leukemia at BFM Centers: Comparable Results With Matched Sibling Donors and Matched Unrelated Donors Mar 19, 2015

Show notes

Review and comments on BFM experience of ALL hematopoietic transplantation.

Is It Biology or Brawn in Ovarian Cancer Surgery? Feb 09, 2015

Show notes

This podcasts provides perspective on a recent report evaluating disease volume and surgical complexity on post-operative tumor residuum and survival in ovarian cancer patients.

Mirror Views: Reflections of Complementary Perspectives in Patient and Clinician Toxicity Reporting Feb 05, 2015

Show notes

In this podcast, Dr. Claire Snyder discusses how patient-reported outcomes provide a critical perspective to evaluating health conditions and their treatment, and describes several tools available to facilitate the measurement and application of PROs.

Dynamic Evolution of ALK Positive Non-Small Cell Lung Cancers and Management of Associated Brain Metastases Jan 23, 2015

Show notes

An analysis of the PROFILE studies and opportunities for treatment of ALK-rearranged non-small cell lung cancer

Prediction of Breast Cancer Risk After a Benign Breast Biopsy: A Practical Model? Jan 21, 2015

Show notes

The development and practical utility of a model developed in the Mayo benign breast disease cohort to predict invasive breast cancer risk after benign breast disease is described.

Prophylactic Anticoagulation in High-Risk Metastatic Germ Cell Tumor Patients: Who Should We Treat? Jan 21, 2015

Show notes

This JCO Podcast provides observations and commentary on the JCO article, "Large retroperitoneal lymphadenopathy as a predictor of venous thromboembolism in patients with disseminated germ cell tumors treated with chemotherapy" by Amirrtha Srikanthan, et al.

The Risk of Second Cancers for Patients with Endometrial and Rectal Cancer Receiving Radiation Therapy Dec 22, 2014

Show notes

This is an oral commentary on patients with endometrial or rectal cancer, and their risk of developing second malignancies with or without radiation.