Journal of Clinical Oncology (JCO) Podcast

Latest Episodes:

Extending the Reach of Targeted Therapy for Hormone Receptor-Positive Advanced Breast Cancer Apr 17, 2018

Show notes

This podcast discusses a phase II trial evaluating the combination of everolimus and fulvestrant compared to fulvestrant alone in pretreated hormone receptor-positive metastatic breast cancer in terms of context within the current hormone treatment environment and toxicity management.

Late Infectious Death: Asplenic Adult Survivors of Child Cancer Apr 17, 2018

Show notes

This podcast discusses a CCSS study of very late infection-related mortality in asplenic adult survivors childhood cancer, with risk increasing precipitously after age 40.

An International Phase II Trial of Single-Agent Nivolumab for Hodgkin Lymphoma Relapsed or Refractory After Autologous Stem Cell Transplant Mar 27, 2018

Show notes

This podcast describes the extended follow-up of the large International phase II CheckMate 205 study of single-agent nivolumab for patients with relapsed/refractory classical Hodgkin lymphoma after failure from autologous stem cell transplant.

Read the related article on JCO.org.

Exploring a New Delivery Model for Germline Genetic Testing for Patients With Ovarian Cancer Mar 20, 2018

Show notes

This podcast provides comment on the accompanying JCO article "ENGAGE: Evaluation of a streamlined oncologist-led BRCA mutation testing and counseling model for patients with ovarian cancer" by Nicoletta Colombo, et al and evaluates the need for new delivery models for genetic testing for oncology patients.

Is Earlier Treatment Better For Patients? The Case of Docetaxel in Metastatic Castration-Sensitive Prostate Cancer Mar 09, 2018

Show notes

This commentary examines whether patient-reported outcomes were substantially different in men given chemohormonal therapy versus hormone therapy in the CHAARTED randomized controlled trial.

The Decision to Image Breast Cancer Patients with Local-Regional Recurrence Jan 31, 2018

Show notes

This podcast reflects upon a recent retrospective study of breast cancer patients with local regional recurrence, and whether imaging is needed for all such patients.

Read the related article on JCO.org.

The Importance of Reading Clinical Trial Protocols Simultaneously With Published Studies Jan 24, 2018

Show notes

This podcast discusses whether the primary outcomes and study design for the reported trial were properly pre-specified and pre-registered prior to accruing participants.

Understanding the 'Value-Added' by Specialized Pediatric Palliative Care Teams in the Care of Children With Cancer at the End of Life Jan 22, 2018

Show notes

This podcast reviews the aims, methodology, and results of a population-level study that investigates the value of specialized pediatric palliative care services for children with cancer at the end of life, as well as discussing practical ways in which individuals and institutions can immediately apply study findings towards improvement of clinical care, education, and research initiatives.

Survival Following Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for Early-Stage Hepatocellular Carcinoma Jan 12, 2018

Show notes

This podcast reviews the current evidence for using radiofrequency ablation or stereotactic body radiotherapy as primary treatment for nonsurgical management of early stage hepatocellular carcinoma.