JACC Specialty Journals

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Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis | JACC: CardioOncology Feb 17, 2026

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This study analyzes over 2,600 transthyretin V142I variant carriers in the Million Veteran Program and finds significantly elevated risks of heart failure, cardiomyopathy, arrhythmias, neuropathy, and musculoskeletal complications compared with matched controls. Despite these risks, amyloidosis was rarely diagnosed clinically, underscoring major gaps in recognition and the need for earlier identification and multidisciplinary intervention.

February 2026 Full Issue Summary | JACC: CardioOncology Feb 17, 2026

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JACC: CardioOncology Volume 8 Issue 1 Full Issue Summary with Introduction by Dr. Bonnie Ky, Editor-in-Chief

Genotype-Guided vs. Conventional P2Y12 Inhibitors in ACS | JACC: CV Interventions | JACC: Cardiovascular Interventions Feb 13, 2026

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Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Mattio Galli, MD, PhD, discuss a recently published original research paper analyzing the role of genotype-guided escalation or de-escalation of antiplatelet therapy in acute coronary syndrome (ACS).

Bleeding in infarct related cardiogenic shock: DanGer Shock substudy | JACC: CV Interventions | JACC: Cardiovascular Interventions Feb 13, 2026

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Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Rikke Sørensen, MD, PhD, discuss a recently published original research paper from DanGer Shock substudy analyzing the bleeding events in patients with infarct related cardiogenic shock.

Brief Introduction - Sex Disparities in Ischemic Heart Disease in South Asia: The Role of Dietary Factors Feb 06, 2026

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